EMBO WORKSHOP
Common Regulatory Mechanisms in Haemopoiesis and Neurogenesis
WEDNESDAY 3RD OCTOBER
SESSION 13.00 pm – 6.30pm
Ligands and Receptors during Organogenesis – I(Chair : Dimitris Kioussis)
3.00-3.30M SaarmaStructure and signaling by GDNF-receptor complexes
3.30-4.00C IbanezNeurotrophic Factors: A Window into Nervous System Development and Function
4.00-4.30V PachnisThe role of Ret signaling in enteric nervous system development.
4.30-5.00Coffee Break
5.00-5.30R MebiusCellular and molecular mechanisms in lymph node development
5.30-6.00D KioussisLymphoid organogenesis and Ret signalling
6.00-6.30G KolliasMesenchymal cell targeting by TNF as a common pathogenic principle in chronic inflammatory
joint and intestinal diseases
7.00-8.30POSTER SESSION - CHEESE AND WINE
THURSDAY 4TH OCTOBER AM
SESSION 2 9.00am – 1.00pm
Ligands and Receptors during Organogenesis – II(Chair : Ruediger Klein)
9.00-9.30A EichmannCommon cues for vessel and nerve guidance
9.30-10.00K Sainio VEGF-C Promotes Proliferation and Survival of the Ret-Dependent Sympathetic Progenitors in
Peripheral Nervous System
10.00-10.30J MilbrandtAxonal protection by Nmnat expression
10.30-11.00Coffee Break
11.00-11.30R KleinEphrin/Eph signaling during remodeling of neuronal and vascular networks
11.30-12.00R AdamsControl of vascular morphogenesis by axon guidance molecules
12.00-12.30M ColesRole of Eph receptor and Ephrin Ligands in foetal thymus development
12.30-12.45 M GuthridgePhosphoserine/phosphotyrosine binary switches in the cytoplasmic tails of cytokine and growth factor receptors control cell survival, proliferation and differentiation.
1.00-3.00Lunch Break
THURSDAY 4TH OCTOBER PM
SESSION 33.00pm – 6.30pm
Chromosomes and Gene Expression(Chair : Richard Flavell)
3.00-3.30R FlavellChromosomal dynamics in cytokine gene expression
3.30-4.00F GrosveldLong range interactions and transcription factor networks
4.00-4.30R GrosschedlRegulation of B lymphopoiesis by EBF proteins
4.30-5.00Coffee Break
5.00-5.30P CharnayMolecular mechanisms of hindbrain segmentation
5.30-6.00 G YancopoulosVelociGene coupled with VelocImmune yield Dll4 as a Tumor Angiogenesis Target
6.00-6.15G MorroneZinc Finger protein 521: A candidate regulator of Haematopoiesis and Neurogenesis
6.15-6.30M VargaThe critical haematopoietic regulator Scl/Tal1 is also involved in vertebrate optic tectum
development
7.00DINNER
FRIDAY 5TH OCTOBER AM
SESSION 49.00am – 1.00pm
Signalling Mechanisms in Development and Function(Chair : David Wilkinson)
9.00-9.30V TybulewiczRole of Rac GTPases and their exchange factors in lymphocyte development and activation
9.30-10.00L FeltriLaminin-initiated signals that shape the development of peripheralnerves
10.00-10.15S. CarrascoRas binding to RasGRP1 defines a mechanism for decoding DAG signals
10.15-10.30A TsagaratouCYLD: A key molecule in T cell development
10.30-11.00Coffee Break
11.00-11.30F RadtkeNotch signaling in lymphopoiesis
11.30-12.00D WilkinsonRoles of Lunatic Fringe and Notch signalling in primary neurogenesis
12.00-12.15E KramerRet function in motor and dopaminergic neurons
12.15-12-30P Melgar-RojasThe role of Notch signalling during embryonic hematopoiesis 2 activity
1.00Lunch Break
FRIDAY 5TH OCTOBER PM
SESSION 53.00pm – 6.30pm
Imaging: from molecules to organs(Chair : Anne Eichmann)
3.00-3.30F BatistaImaging the B cell response to antigen in vivo and at high molecular resolution
3.30-3.45S TaravirasCo-ordination of cellular proliferation and differentiation:The role of the cell cycle inhibitor
Geminin in immune and nervous system development and homeostasis
3.45-4.00A JohnEssential role of the C2H2 zinc finger transcription factor Bcl11a during nervous system
development
4.00-4.15L PoljakJak-1/Smad-signaling dependent gene expression and brain repair reaction
4.15-4.30A FloraA new role for the E-protein Tcf4/E2.2 in the development of the mammalian nervous system
4.30-5.00Coffee Break
5.00-0-5.30F CostantiniThe role of GDNF/Ret signaling in renal branching morphogenesis
5.30-5.45P Gilardi-Hebenstreit Krox20 controls the transcription of its various targets in the developing hindbrain according
to multiple modes
5.45-6.00K GoetzOlig2 is a direct target of Iroquois transcription factors
6.00-6.15A KenneyInsulin Receptor Substrate 1 is an essential node of mitogenic cross-talk between the Sonic
hedgehog and Inulin-like growth factor signalling pathways in neural precursors
6.15-6.30C LancrinThe Haemangioblast generates haematopoietic cells through the formation of a haemogenic
endothelium intermediate stage
DEPARTURE