‘Sink or swim’: an evaluation of the clinical characteristics of individuals with High Bone Mass. Osteoporosis International. Celia L Gregson et al. University of Bristol, Musculoskeletal Research Unit.

Online Resource table 2

Characteristics of High Bone Mass index cases who participated compared with those who did not participate

HBM
participants
(Z ≥ +3.2) / HBM
Non-participants
(Z ≥ +3.2) / p value
n / 258 / 284
Female (%) / 203 (78.7%) / 217 (76.4%) / 0.527
Caucasian (%) / 255 (98.8%) / 273 (96.1%) / 0.078
Earliest DXA scan date / 16-Jul-92 / 11-Nov-92
Latest DXA scan date / 05-Mar-10 / 04-May-10
Age (years) / 59.9 (56.2, 63.6) / 60.4 (58.7, 62.1) / 0.341
Weight (kg) / 86.2 (81.4, 90.9) / 85.6 (83.4, 87.7) / 0.922
Height (cm) / 168.5 (166.0, 171.1) / 166.3 (165.1, 167.5) / 0.013
BMI (kg/m2) / 29.3 (24.5, 34.0) / 31.0 (28.8, 33.1) / 0.196
sBMD(mg/cm2)
Right hip (R) / 1305.9(1201.7, 1410.1) / 1271.6(1226.4, 1316.9) / 0.323
Left hip (L) / 1311.6(1250.3, 1372.9) / 1263.3(1235.4, 1291.2) / 0.012
Max hip (of L & R) / 1315.0(1254.8, 1375.1) / 1267.4(1240.0, 1294.8) / 0.012
L1 / 1396.9 (1320.3, 1473.5) / 1415.6(1380.8, 1450.5) / 0.436
L2 / 1513.5(1435.5, 1591.6) / 1547.6(1512.1, 1583.1) / 0.164
L3 / 1613.9(1532.0, 1695.9) / 1660.3(1623.1, 1697.6) / 0.072
L4 / 1613.1(1517.6, 1708.5) / 1658.6(1615.2, 1701.9) / 0.129
DXA Z scores
Right hip (R) / 3.29 (2.85, 3.74) / 3.21 (3.01, 3.40) / 0.564
Left hip (L) / 3.52 (3.10, 3.93) / 3.29 (3.11, 3.47) / 0.089
Max hip (of L & R) / 3.40 (3.07, 3.73) / 3.25 (3.11, 3.40) / 0.158
L1 / 4.07 (3.64, 4.50) / 4.29 (4.10, 4.48) / 0.106
L2 / 4.61 (4.16, 5.07) / 4.80 (4.60, 5.00) / 0.198
L3 / 5.27 (4.79, 5.75) / 5.42 (5.21, 5.64) / 0.326
L4 / 5.25 (4.73, 5.77) / 5.39 (5.16, 5.63) / 0.385

DXA: Dual energy X-ray absorptiometry. L1 to L4 indicate sequential lumbar vertebrae.

Complete data from 542 (86.2%) of 629 index cases identified were available (with Z score at total hip or L1 ≥+3.2). Means and 95% CIs presented. p values: χ2 for categorical variables and linear regression for continuous variables. sBMD: Standardized Bone Mineral Density calculated as;

Lumbar spine sBMD = 1000 [1.0550 (BMDHologic- 0.972) + 1.0436] & sBMD = 1000 [0.9683 (BMDLunar – 1.100) + 1.0436], Total hip sBMD = 1000 [1.008 x BMDHologic + 0.006] & sBMD = 1000 [0.979 x BMDLunar – 0.031] (23;24)