International Conference organised by the

European Directorate for the Quality of Medicines & HealthCare (EDQM), Council of Europe

CERTIFICATION PROCEDURE

1992 - 2012: 20 Years of Experience

22-23 March 2012

Duration: 1.5 days, Location: Palm Beach Hotel, Larnaca, Cyprus

Working language: English

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PROGRAMME

Thursday, 22 March 2012

8:00-9:00 Registration

9:00-9:10 Opening remarks

Dr Susanne Keitel, Director of the European Directorate for the Quality of Medicines & HealthCare (EDQM), Council of Europe

Welcome Address

Mr George Antoniou, Ministry of Health, Pharmaceutical Services, Republic of Cyprus

PLENARY SESSION

Moderator: Dr Mike Morris, Chair of the Certification Steering Committee

9:10-9:25 The Evolution of the European Pharmacopoeia and its impact on the Certification procedure

Dr Marianne Ek, Chair of the European Pharmacopoeia Commission

9:25-9:45 New developments in Certification and place of the procedure within the European regulatory framework

Dr Jean-Louis Robert, Chair of the Joint CHMP/CVMP Quality Working Party and Former Chair of the Certification Steering Committee

9:45-10:15 ‘Remember the Pioneers’

Why did we invent the Certification Procedure? - Could not live without it!

Prof. Per Helboe, First Chair of the Technical Advisory Board (TAB) for the Certification Procedure

Where do we stand after 20 years of running the certification procedure? A review

Dr Wilhelm Schlumbohm, Assessor for the Certification Procedure and Former Member of the TAB, BVL, Germany

10:15-10:45 Coffee break

10:45-11:05 Use of CEPs outside Europe: Health Canada’s experience

Dr Amirthini Rajkumar, Health Canada

11:05-11:25 Use of CEPs outside Europe: Therapeutic Goods Administration’s experience

Dr Michael Pass, Therapeutic Goods Administration, Australia

11:25-11:45 Inspections of API manufacturers: What is new? What are the new challenges to face? Opportunities of international collaboration

Mr Olivier Gross, Scientific Administrator, EMA

11:45-12:05 Inspections of API manufacturers: Experience of the EDQM

Dr Thomas Hecker, Inspector, EDQM, Council of Europe

12:05-12:35 Discussion

12:35 -14:00 Lunch break

WORKSHOP SESSIONS

There will be three parallel workshops (1st Session: 14:00-15:30 and 2nd Session: 16:00-17:30)

You are required to choose two workshops you wish to participate in when registering.

Time / Workshop 1 / Workshop 2 / Workshop 3
1st Session
14:00-15:30 / Process description and definition of starting materials / The EDQM inspection programme and international collaboration in the area of inspections of API manufacturers / Quality of antibiotics and fermentation products
15:30-16:00 / Coffee Break
2nd Session
16:00-17:30
(Repeated) / Process description and definition of starting materials / The EDQM inspection programme and international collaboration in the area of inspections of API manufacturers / Quality of antibiotics and fermentation products

§  WORKSHOP 1: Process description and definition of starting materials

Moderator: Dr Andrew McMath, Scientific Administrator, EDQM, Council of Europe

o  National assessor taking part in Certification

Dr Cornelia Nopitsch Mai, Federal Ministry of Health, Germany

o  Industry representative

Mrs Hilde Vanneste, Cefic/APIC

o  National Inspector

Mr Lionel Viornery, Afssaps, France

§ WORKSHOP 2: The EDQM inspection programme and international collaboration in the area of inspections of API manufacturers

Moderator: Dr Thomas Hecker, Inspector, EDQM, Council of Europe

o  U.S. Food and Drug Administration - FDA

Dr Janice Soreth, Deputy Director, FDA Europe Office, Liaison to EMA

o  Therapeutic Goods Administration – TGA – Australian Inspectorate

Mr Bill Turner, Office Head of the Office of Manufacturing Quality

o  European Medicines Agency - EMA

Mr Olivier Gross, Scientific Administrator

§ WORKSHOP 3: Quality of antibiotics and fermentation products

Moderator: Mrs Hélène Bruguera, Head of the Certification of Substances Division, EDQM, Council of Europe

o  Quality of fermentation products

Prof. Jos Hoogmartens, Chair of the EDQM Group of Experts on Antibiotics

o  New EU Guideline on antibiotics

Dr Tone Agasoster, Norwegian Medicines Agency

o  European Pharmacopoeia (Ph. Eur.) monographs for fermentation products

Dr Jan W. H. Smeets, Expert of the EDQM Group of Experts on Antibiotics


Friday, 23 March 2012

PLENARY SESSION

Moderator: Dr Susanne Keitel, Director, EDQM, Council of Europe

9:00-10:00 9:00-10:00 Feedback from the Workshops

Dr Mike Morris, Chair of the Certification Steering Committee

10:00-11:50 The Interests, Use and Limits of Certificates: Viewpoints from the industry and regulatory authorities

Industry Associations

10:00-10:10 European Federation of the Pharmaceutical Industries and Associations (EFPIA)

Dr Georges France, Vice President Global Quality Strategy & International Affiliate Quality & Compliance (Novartis, Switzerland)

10:10-10:20 European Generic Medicines Association (EGA)

Dr Elli Souli, Regulatory Affairs Supervisor (Medochemie Ltd, Cyprus)

10:20-10:30 Association of the European Self-Medication Industry (AESGP) – Views of the self-care Sector

Dr Christelle Anquez-Traxler, Regulatory and Scientific Affairs Manager (AESGP)

10:30-10:40 European Chemical Industry Council (Cefic) / Active Pharmaceutical Ingredients Committee (APIC)

Mrs Hilde Vanneste, Associate Director Global CMC Regulatory Affairs (Janssen Pharmaceutica NV, Belgium)

10:40-10:50 China Chamber of Commerce for Import & Export of Medicines & Health Products (CCCMHPIE)

Dr Ming Xu, Vice President (CCCMHPIE)

10:50-11:20 Coffee break

11:20-11:40 Regulatory authorities from Europe

Mr Malcolm Dash, MHRA, United Kingdom

11:40-12:15 Discussion

12:15-12:45 The benefits and cross-functional links between the Certification procedure, the European Pharmacopoeia, the EMA and National Authorities

Dr Jean-Louis Robert, Chair of the Joint CHMP/CVMP Quality Working Party and Former Chair of the Certification Steering Committee

12:50 Close of meeting

13:00 Lunch

For further information, please contact the EDQM Public Relations Division & Documentation:

Mrs F. Baumgarthen, Tel.: +33 (0)3 88 41 28 24 *, Fax: +33 (0)3 88 41 27 71 *,

E-mail:

Postal address: EDQM, 7 allée Kastner, CS 30026, F-67081 Strasbourg, France

* Leave out 0 if calling from outside France