Supplementary Table 1

Prognostic factors for overall survival analyzed by multivariable Cox proportional hazard ratio.

Factors / Univariate / Multivariate
No. / HR / 95% CI / P / HR / 95% CI / P
Sex
Male
Female / 44
35 / 0.457 / 0.174-1.197 / 0.111
Age (years)
≤60
>60 / 53
26 / 1.605 / 0.663-3.883 / 0.294
Operation period
2000-2009
2010-2015 / 34
45 / 0.418 / 0.131-1.336 / 0.141
Perirenal location / 73 / 0.464 / 0.133-1.610 / 0.226
Organ invasion / 35 / 4.795 / 1.828-12.574 / 0.001 / 2.566 / 0.375-17.561 / 0.337
No. of resected organ
Less than 3
3 or more / 65
14 / 4.604 / 1.652-12.830 / 0.004 / 3.798 / 0.823-17.519 / 0.087
Operation method
No nephrectomy
Only mass excision
Combined organ resection
Combined nephrectomy
Only nephrectomy
Combined organ resection / 9
2
35
33 / 109.2
0.958
3.754 / 5.115-2332.3
0.202-4.533
0.985-14.299 / 0.004
0.003
0.957
0.053 / 127.62
1.406
9.766 / 2.492-6535.4
0.093-21.360
1.242-76.776 / 0.036
0.016
0.806
0.030
Histologic margin
Unknown
Positive / 59
20 / 2.535 / 1.035-6.209 / 0.042 / 6.713 / 1.191-37.831 / 0.031
Differentiation
WDPLS
DDLPS and others / 31
48 / 2.891 / 1.074-7.779 / 0.036 / 3.046 / 0.145-64.057 / 0.474
FNCLCC Grade
1
2
3 / 33
28
13 / 1.757
5.749 / 0.449-6.878
1.708-19.349 / 0.022
0.418
0.005 / 1.113
6.126 / 0.198-6.266
1.314-28.567 / 0.040
Radiotherapy / 34 / 0.397 / 0.151-1.043 / 0.061

WDLPS Well-differentiated liposarcoma, DDLPSDe-differentiated liposarcoma

Supplementary Figure 1.Examples of cases included in the study. A, A huge mass with core located above the right renal artery abutting the perirenal fat with no displacement. B,A huge liposarcoma displacing the right kidney to the midline of the abdomen.C,An infrarenal liposarcoma inducing hydronephrosis of the right kidney.

Supplementary Figure 2. A Kaplan-Meier overall survival curve of patients with retroperitoneal liposarcoma near the kidney B Survival curves of patients divided by operation method analyzed with multivariable Cox analyses for prognostic factors on overall survival.

A.

B.