Addional data file 1
Fold change
Accession ID / Gene Name
(Annotated January 14, 2004) / Cytogenetic Position / T2D vs. C / T2DN vs. C / T2DN vs. T2D / Broad Function
AA043551 / UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 / 3q28 / 2.05 / -4.29 / -8.77 / enzyme
H29513 / hypothetical protein FLJ10193 / 17p11.2 / 4.11 / -1.59 / -6.52
N91101 / EST / 3.52 / -1.59 / -5.61
AA456156 / uroporphyrinogen III synthase (congenital erythropoietic porphyria) / 10q25.2-q26.3 / 4.09 / -1.20 / -4.91 / enzyme
H65231 / EST / 4.25 / -1.09 / -4.63
W76331 / leukotriene B4 12-hydroxydehydrogenase / 9q32 / 4.70 / 1.02 / -4.60 / enzyme
H54629 / tumor necrosis factor (ligand) superfamily, member 10 / 3q26 / 4.28 / -1.06 / -4.54 / signal transducer
W95626 / EST / 1.95 / -2.30 / -4.50
AA424575 / hematopoietic cell-specific Lyn substrate 1 / 3q13 / 4.93 / 1.10 / -4.47 / nucleic acid binding
W95480 / similar to RIKEN cDNA 2310038H17 / 13q33.1 / 4.58 / 1.07 / -4.29
W80591 / hepatocellular carcinoma-associated antigen 59 / 9q34.2 / 2.76 / -1.38 / -3.81
AA487681 / ornithine decarboxylase antizyme 1 / 19p13.3 / 3.30 / -1.11 / -3.68 / enzyme inhibitor
R22065 / Homo sapiens transcribed sequences / 1.52 / -2.40 / -3.66
AA132094 / down-regulator of transcription 1, TBP-binding (negative cofactor 2) / 1p22.1 / 3.63 / 1.02 / -3.55 / nucleic acid binding
H20442 / hypothetical protein FLJ20507 / 2q11.2 / 1.85 / -1.89 / -3.50
AA056734 / KIAA1110 protein / 12p13.33 / 3.34 / -1.04 / -3.46
AA130671 / stromal cell derived factor receptor 1 / 15q22 / 2.11 / -1.62 / -3.41
AA192419 / biliverdin reductase A / 7p14-cen / 3.14 / -1.08 / -3.40 / enzyme
R54105 / dihydropyrimidinase-like 5 / 2p23.3 / 2.25 / -1.48 / -3.34
N23112 / protein kinase, AMP-activated, alpha 1 catalytic subunit / 5p12 / 2.36 / -1.39 / -3.28 / enzyme
AA487262 / hypothetical protein MGC20235 / 17q21.31 / 2.58 / -1.27 / -3.28
AA401853 / proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 / 12q24.31-q24.32 / 3.55 / 1.11 / -3.20 / ligand binding or carrier
R99220 / like mouse brain protein E46 / 22q13.31 / 2.36 / -1.34 / -3.17 / unknown
H57273 / EST / 2.74 / -1.14 / -3.11
W04713 / transcription factor RAM2 / 7p15.3 / 1.59 / -1.95 / -3.09
T54164 / EST / 2.15 / -1.39 / -2.98
AA453202 / nuclear receptor subfamily 1, group D, member 1 / 17q11.2 / 2.84 / -1.05 / -2.98 / nucleic acid binding
W95076 / Homo sapiens transcribed sequences / 2.45 / -1.21 / -2.96
H55907 / GrpE-like 1, mitochondrial (E. coli) / 4p16 / 3.82 / 1.29 / -2.96 / chaperone
H22568 / solute carrier family 36 (proton/amino acid symporter), member 4 / 11q14.3 / 2.04 / -1.44 / -2.94
AA410383 / chemokine (C-X-C motif) ligand 13 (B-cell chemoattractant) / 4q21 / 1.95 / -1.49 / -2.90 / signal transducer
AA436372 / zinc finger protein 151 (pHZ-67) / 1p36.2-p36.1 / 3.17 / 1.10 / -2.87 / ligand binding or carrier
W74657 / Kruppel-like factor 2 (lung) / 19p13.13-p13.11 / 1.94 / -1.47 / -2.86 / nucleic acid binding
AA180453 / EST / 1.60 / -1.77 / -2.83
AA174088 / Homo sapiens transcribed sequences / 2.73 / -1.04 / -2.83
H79353 / Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide / 1q23 / 3.37 / 1.22 / -2.75 / signal transducer
AA173888 / Homo sapiens transcribed sequence with weak similarity to protein ref:NP_060312 / 1.74 / -1.54 / -2.68
AA070487 / hypothetical protein MGC34132 / 3p14.2 / 2.06 / -1.29 / -2.66
H91216 / Homo sapiens histone 1, H2ac, mRNA (cDNA clone IMAGE:6526471), partial cds / 2.79 / 1.06 / -2.63
R33841 / EST / 2.28 / -1.15 / -2.62
AA411900 / Mov10l1, Moloney leukemia virus 10-like 1, homolog (mouse) / 22q13.33 / -1.07 / -2.79 / -2.62
AA055807 / Homo sapiens transcribed sequences / 1.86 / -1.39 / -2.60
H68845 / peroxiredoxin 2 / 19p13.2 / 2.40 / -1.08 / -2.58 / enzyme
W57767 / similar to ENSANGP00000010412 / 1p34.1 / 1.28 / -2.00 / -2.56
R38300 / EST / 2.18 / -1.17 / -2.55
R93875 / nucleosome assembly protein 1-like 1 / 12q21.1 / 2.95 / 1.16 / -2.54
R37411 / guanine deaminase / 9q21.11-21.33 / 1.29 / -1.93 / -2.49
H85355 / EST / 1.29 / -1.91 / -2.47
H20570 / KIAA1391 protein / 11q23.2 / 1.75 / -1.41 / -2.46
AA599078 / signal recognition particle 54kDa / 14q13.2 / 2.06 / -1.20 / -2.46 / ligand binding or carrier
R66235 / EST / 1.65 / -1.48 / -2.43
AA461492 / similar to fibrillar collagen precursor / 5q33.1 / 2.25 / -1.08 / -2.43
AA447598 / Homo sapiens transcribed sequences / 2.13 / -1.13 / -2.42
AA453925 / KIAA0157 protein / 10q26.2 / 1.96 / -1.22 / -2.39
AA490771 / UV radiation resistance associated gene / 11q13.5 / 2.89 / 1.21 / -2.39
R06378 / Homo sapiens clone DT1P1B6 mRNA, CAG repeat region / 1.87 / -1.28 / -2.39
N48080 / G-protein coupled receptor 88 / 1p21.3 / 1.49 / -1.57 / -2.34 / signal transducer
N40202 / Homo sapiens transcribed sequences / 1.73 / -1.34 / -2.32
AA521389 / tumor protein p53 binding protein, 1 / 15q15-q21 / 1.45 / -1.59 / -2.30 / ligand binding or carrier
W72231 / x 006 protein / 17p13.1 / 2.21 / -1.04 / -2.29
H71314 / EST / -1.02 / -2.35 / -2.29
AA182680 / ubiquitin specific protease 9, Y-linked (fat facets-like, Drosophila) / Yq11.2 / 1.56 / -1.47 / -2.28 / enzyme
R01272 / hypothetical protein FLJ20618 / 22q12.2 / 1.95 / -1.17 / -2.28
N47954 / hippocalcin like 4 / 1p34.2 / 1.87 / -1.22 / -2.27
T88816 / EST / -1.02 / -2.32 / -2.27
R25825 / N-acetylgalactosaminidase, alpha- / 22q13-qter / 1.66 / -1.36 / -2.25 / enzyme
AA056580 / 44050 protein / 10q24.2 / 1.84 / -1.22 / -2.25
N24157 / chromosome 6 open reading frame 35 / 6q25.3 / 2.17 / -1.04 / -2.25
H48677 / caldesmon 1 / 7q33 / 2.75 / 1.22 / -2.25
R95913 / chromosome 14 open reading frame 117 / 14q24.2 / 1.29 / -1.73 / -2.23
H18433 / Homo sapiens transcribed sequences / 1.01 / -2.18 / -2.21
H16637 / vascular cell adhesion molecule 1 / 1p32-p31 / 1.77 / -1.24 / -2.20 / cell adhesion
AA676749 / dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A / 21q22.13 / 1.56 / -1.41 / -2.20 / enzyme
AA421266 / WD repeat domain 5 / 9q34 / 1.40 / -1.55 / -2.18
AA004816 / Homo sapiens clone ZI25H08 mRNA sequence / 1.37 / -1.59 / -2.18
H78182 / EST / 1.39 / -1.57 / -2.18
AA416984 / hypothetical protein MGC27085 / 3q26.31 / 1.83 / -1.19 / -2.16
AA454880 / EST / 1.96 / -1.11 / -2.16
N66068 / ubiquitin specific protease 42 / 7p22.2 / 1.94 / -1.11 / -2.16 / enzyme
H66005 / Homo sapiens transcribed sequences / -1.06 / -2.29 / -2.16
N73201 / EST / 1.52 / -1.42 / -2.15
T41149 / heterogeneous nuclear ribonucleoprotein R / 1p36.11 / 1.39 / -1.54 / -2.15 / nucleic acid binding
W35203 / chitobiase, di-N-acetyl- / 1p22 / 1.88 / -1.14 / -2.14
W72621 / RING1 and YY1 binding protein / 3p14.2 / 1.93 / -1.11 / -2.14 / transcription factor binding
W67228 / Homo sapiens transcribed sequence with weak similarity to protein ref:NP_060312 / 1.21 / -1.76 / -2.13
H85454 / potassium voltage-gated channel, delayed-rectifier, subfamily S, member 1 / 20q12 / -1.06 / -2.25 / -2.13 / ligand binding or carrier
AA456595 / hypothetical protein MGC12904 / 9q33.1 / 1.96 / -1.08 / -2.12
AA476221 / hypothetical protein FLJ30932 / 19p13.2 / 1.85 / -1.14 / -2.11 / nucleic acid binding
AA634028 / major histocompatibility complex, class II, DP alpha 1 / 6p21.3 / 1.17 / -1.80 / -2.10
AA454165 / zinc finger protein, X-linked / Xp21.3 / 1.49 / -1.40 / -2.09 / nucleic acid binding
R56219 / cadherin 8, type 2 / 16q22.1 / 1.92 / -1.09 / -2.09 / cell adhesion
N66591 / retinoblastoma binding protein 6 / 16p12.2 / 1.36 / -1.53 / -2.08 / ligand binding or carrier
AA443557 / protocadherin 1 (cadherin-like 1) / 5q32-q33 / 2.38 / 1.15 / -2.07
T83098 / adducin 2 (beta) / 2p14-p13 / 2.11 / 1.02 / -2.07 / ligand binding or carrier
AA451781 / dynactin 6 / 8p12-p11 / 1.41 / -1.47 / -2.07 / enzyme
AA490902 / guanylate kinase 1 / 1q32-q41 / 2.44 / 1.18 / -2.07 / enzyme
R58974 / EST / 1.06 / -1.95 / -2.06
R47893 / chemokine (C-C motif) ligand 3-like 1 / 17q21.1-q21.3 / 1.13 / -1.83 / -2.06
W00946 / hypothetical protein MGC7036 / 12q24.31 / 1.44 / -1.42 / -2.05
AA398949 / PCTAIRE protein kinase 3 / 1q31-q32 / 1.54 / -1.33 / -2.05
N47208 / hypothetical protein MGC24995 / 1p32.3 / 1.74 / -1.17 / -2.04
AA448641 / E2F transcription factor 4, p107/p130-binding / 16q21-q22 / 1.22 / -1.67 / -2.04 / nucleic acid binding
R80235 / Mdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse) / 12q14.3-q15 / 1.12 / -1.82 / -2.03
N73278 / Homo sapiens mRNA; cDNA DKFZp586I1823 (from clone DKFZp586I1823) / 1.25 / -1.63 / -2.03
AA608988 / testis specific protein, Y-linked / Yp11.2 / 1.19 / -1.71 / -2.03
R16838 / cytochrome P450, family 17, subfamily A, polypeptide 1 / 10q24.3 / 1.72 / -1.18 / -2.03 / enzyme
H21074 / Homo sapiens clone 24626 mRNA sequence / 1.27 / -1.60 / -2.03
AA459572 / protein phosphatase 1, regulatory subunit 7 / 2q37.3 / 1.86 / -1.09 / -2.02 / enzyme
AA034183 / hypothetical protein FLJ23027 / 14q32.32 / 1.31 / -1.54 / -2.02
H42037 / Homo sapiens full length insert cDNA YO61A08 / 1.35 / -1.49 / -2.01
N49526 / v-myb myeloblastosis viral oncogene homolog (avian) / 6q22-q23 / 1.57 / -1.28 / -2.01
AA487192 / Homo sapiens, clone IMAGE:3453158, mRNA / 1.99 / -1.01 / -2.01
AA453991 / hypothetical protein MGC3222 / 3p25.1 / 1.74 / -1.15 / -2.01
T90767 / cyclin T1 / 12pter-qter / 1.57 / -1.28 / -2.00
T63981 / hypothetical protein MGC16202 / 10q23.33 / 1.39 / -1.44 / -2.00
AA676590 / telomeric repeat binding factor 2 / 16q22.1 / 1.64 / -1.22 / -2.00
AA455126 / ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c (subunit 9), / 12q13.13 / 1.14 / -1.75 / -2.00 / ligand binding or carrier
AA127234 / psoriasis susceptibility 1 candidate 1 / 6p21.3 / 1.67 / -1.20 / -2.00
R01619 / Homo sapiens transcribed sequence with moderate similarity to protein pir:E54024 / 2.18 / 1.11 / -1.96
H21520 / rap2 interacting protein x / 4q21.1 / 2.01 / 1.03 / -1.94
H01039 / Homo sapiens transcribed sequence with strong similarity to protein pir:A47501 ( / 3.26 / 1.68 / -1.93
AA485974 / golgi autoantigen, golgin subfamily b, macrogolgin (with transmembrane signal), / 3q13 / 2.30 / 1.20 / -1.93
R22856 / Homo sapiens transcribed sequence with weak similarity to protein ref:NP_071431 / -1.18 / -2.25 / -1.92
N51290 / Homo sapiens cDNA FLJ43343 fis, clone NT2RI3008055 / -1.34 / -2.56 / -1.90
N51842 / Homo sapiens cDNA FLJ10967 fis, clone PLACE1000798. / -1.10 / -2.09 / -1.90
N52043 / chromosome 6 open reading frame 65 / 6p12.1 / -1.14 / -2.15 / -1.89
N47443 / KIAA0390 gene product / 19q13.11 / 2.03 / 1.08 / -1.88
AA130193 / acheron / 15q22.32 / 2.67 / 1.42 / -1.88 / nucleic acid binding
N63864 / Homo sapiens transcribed sequences / 2.01 / 1.08 / -1.86
AA620669 / Homo sapiens transcribed sequences / -1.27 / -2.34 / -1.84
AA186686 / prostaglandin E synthase 2 / 9q34.13 / -1.20 / -2.14 / -1.79 / ligand binding or carrier
AA099855 / popeye domain containing 2 / 3q13.33 / -1.98 / -3.52 / -1.78
AA004803 / Homo sapiens transcribed sequences / -1.25 / -2.19 / -1.76
AA609332 / Homo sapiens transcribed sequences / -1.22 / -2.11 / -1.73
H70813 / hypothetical protein FLJ11457 / 2q31.1 / -1.42 / -2.45 / -1.72
W70051 / M-phase phosphoprotein 9 / 12q24.31 / 2.00 / 1.21 / -1.65
AA045342 / hypothetical protein FLJ23047 / 3q12.3 / -1.63 / -2.66 / -1.63
W45165 / capping protein (actin filament) muscle Z-line, beta / 1p36.1 / 2.04 / 1.29 / -1.57 / ligand binding or carrier
AA029647 / late envelope protein 3 / 1q21.3 / -1.54 / -2.41 / -1.56
AA099404 / hypothetical protein MGC22793 / 7q22.1 / -1.36 / -2.10 / -1.55
N74052 / Homo sapiens transcribed sequences / -1.68 / -2.61 / -1.55
R00809 / calcium channel, voltage-dependent, alpha 2/delta subunit 2 / 3p21.3 / -1.35 / -2.09 / -1.54
AA497030 / Homo sapiens transcribed sequences / -1.42 / -2.19 / -1.54
AA026686 / EST / 2.28 / 1.48 / -1.54
N22827 / ferredoxin 1 / 11q22 / -1.31 / -2.02 / -1.54 / ligand binding or carrier
N39408 / cyclin-dependent kinase 5, regulatory subunit 2 (p39) / 2q35 / -1.43 / -2.19 / -1.53
AA663828 / calmodulin 3 (phosphorylase kinase, delta) / 19q13.2-q13.3 / 2.02 / 1.32 / -1.53 / ligand binding or carrier
AA464568 / proteasome (prosome, macropain) 26S subunit, ATPase, 4 / 19q13.11-q13.13 / -1.71 / -2.58 / -1.51 / enzyme
AA460669 / CDC26 subunit of anaphase promoting complex / 9q32 / -1.87 / -2.81 / -1.50
N48571 / Homo sapiens full length insert cDNA clone YY74A01 / 2.04 / 1.36 / -1.50
AA035347 / glucosamine (N-acetyl)-6-sulfatase (Sanfilippo disease IIID) / 12q14 / 2.27 / 1.55 / -1.46 / enzyme
AA459868 / Homo sapiens cDNA clone IMAGE:3453243 / -2.77 / -4.05 / -1.46
AA431181 / thyroid hormone receptor-associated protein, 95-kD subunit / 19p13.3 / 2.42 / 1.67 / -1.45 / transcription factor binding
AA401482 / Homo sapiens, clone IMAGE:4821566, mRNA / -1.43 / -2.01 / -1.41
H64601 / interleukin 17 receptor B / 3p21.1 / -1.62 / -2.27 / -1.40 / signal transducer
AA432106 / hypothetical protein FLJ11046 / 3q12.3 / -1.44 / -2.02 / -1.40
AA164782 / CocoaCrisp / 8q13.3 / -1.49 / -2.08 / -1.39
AA489028 / squamous cell carcinoma antigen recognised by T cells 3 / 12q24.1 / -1.50 / -2.08 / -1.38
AA074079 / Homo sapiens, clone IMAGE:5302006, mRNA / -1.75 / -2.41 / -1.38
AA401438 / Homo sapiens transcribed sequences / -2.05 / -2.81 / -1.37
N78703 / Homo sapiens transcribed sequence with weak similarity to protein ref:NP_062553 / -1.50 / -2.04 / -1.35
W32296 / Homo sapiens transcribed sequences / -1.55 / -2.08 / -1.34
AA461092 / RNA binding motif protein, X-linked / Xq26 / -2.06 / -2.75 / -1.34 / nucleic acid binding
H10995 / Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 35907 / -1.67 / -2.20 / -1.32
N30704 / EST / -1.95 / -2.56 / -1.32
AA401437 / KIAA1799 protein / 1p31.3 / -1.61 / -2.09 / -1.30
R76782 / O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polyp / Xq13 / -2.35 / -2.98 / -1.27
W67368 / Homo sapiens transcribed sequence with weak similarity to protein ref:NP_060312 / -2.12 / -2.66 / -1.26
H94739 / putative MAPK activating protein PM20,PM21 / 1p36.13 / -2.11 / -2.65 / -1.26
AA481789 / EST / -1.80 / -2.19 / -1.22
AA459692 / Homo sapiens transcribed sequences / -1.89 / -2.29 / -1.21
AA463458 / glutathione synthetase / 20q11.2 / 2.02 / 1.68 / -1.20 / enzyme
N69913 / Homo sapiens cDNA FLJ42666 fis, clone BRAMY2020050 / -2.35 / -2.77 / -1.18
H94944 / v-ral simian leukemia viral oncogene homolog A (ras related) / 7p15-p13 / -1.96 / -2.30 / -1.18 / enzyme
AA004810 / Homo sapiens transcribed sequences / 2.36 / 2.03 / -1.17
W69913 / EST / -2.44 / -2.84 / -1.16
N73846 / Zinc finger, FYVE domain containing 19 / 15q14 / -1.73 / -2.01 / -1.16
N90968 / Homo sapiens transcribed sequences / 2.18 / 1.90 / -1.15
AA455146 / acetyl-Coenzyme A synthetase 2 (ADP forming) / 20q11.23 / -2.21 / -2.50 / -1.13 / enzyme
AA192453 / EST / -1.87 / -2.11 / -1.13
N51883 / Homo sapiens transcribed sequences / 2.05 / 1.81 / -1.13
AA429034 / HGFL gene / 22q12.2 / 2.32 / 2.06 / -1.13
R96522 / EST / -1.88 / -2.03 / -1.08
AA460963 / Homo sapiens transcribed sequence with strong similarity to protein ref:NP_07897 / -2.36 / -2.53 / -1.07
AA609746 / Homo sapiens transcribed sequences / -1.96 / -2.09 / -1.07
T84703 / Homo sapiens transcribed sequences / 3.36 / 3.18 / -1.06
AA443094 / translocase of outer mitochondrial membrane 40 homolog (yeast) / 19q13 / 2.03 / 1.93 / -1.05 / transporter
AA488526 / nucleolar and coiled-body phosphoprotein 1 / 10q24.32 / 2.03 / 1.95 / -1.04 / ligand binding or carrier
W74216 / peptidoglycan recognition protein-I-beta precursor / -1.96 / -2.02 / -1.03
R92199 / Homo sapiens transcribed sequence with weak similarity to protein ref:NP_060265 / -2.08 / -2.12 / -1.02
AA025268 / centaurin, beta 5 / -2.61 / -2.61 / 1.00
AA152178 / neuron navigator 2 / 11p15.1 / 2.95 / 3.03 / 1.03
H48389 / Homo sapiens transcribed sequences / -2.25 / -2.18 / 1.03
AA148200 / TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa / 11p15.3 / -2.19 / -2.11 / 1.04 / nucleic acid binding
AA400412 / RAD9 homolog B (S. cerevisiae) / 12q24.13 / -2.25 / -2.06 / 1.09
AA401392 / TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 5 / Xq22.1 / -2.33 / -2.12 / 1.10
N22297 / hypothetical protein FLJ90430 / 7q11.21 / 1.80 / 2.01 / 1.11 / ligand binding or carrier
AA489498 / salvador homolog 1 (Drosophila) / 14q13-q23 / -2.33 / -2.07 / 1.12
AA486104 / proline synthetase co-transcribed homolog (bacterial) / 8p11.2 / -2.29 / -2.03 / 1.13 / unknown
AA102634 / TNF receptor-associated factor 5 / 1q32 / -2.22 / -1.91 / 1.16 / ligand binding or carrier
L06499 / ribosomal protein L37a / 2q35 / -2.44 / -2.09 / 1.17 / nucleic acid binding
AA621001 / Homo sapiens transcribed sequences / 4.64 / 5.49 / 1.18
AA136071 / Homo sapiens transcribed sequences / -2.31 / -1.95 / 1.19
R87840 / intercellular adhesion molecule 5, telencephalin / 19p13.2 / 1.93 / 2.30 / 1.19
R53428 / ATP-binding cassette, sub-family A (ABC1), member 5 / 17q24.3 / -2.07 / -1.71 / 1.21 / ligand binding or carrier
R70174 / ubiquitin specific protease 13 (isopeptidase T-3) / 3q26.2-q26.3 / -3.40 / -2.76 / 1.23 / enzyme
R06321 / hydroxymethylbilane synthase / 11q23.3 / 1.94 / 2.39 / 1.24 / enzyme
AA088428 / Homo sapiens transcribed sequences / -2.13 / -1.71 / 1.24
N72116 / solute carrier family 11 (proton-coupled divalent metal ion transporters), membe / 12q13 / -2.77 / -2.20 / 1.26 / transporter
AA453283 / protocadherin beta 16 / 5q31 / -2.80 / -2.21 / 1.27
AA180455 / EST / -2.31 / -1.80 / 1.28
N50770 / esophageal cancer associated protein / 16p13.11 / 1.62 / 2.08 / 1.28
R69790 / hypothetical protein MGC4701 / 4p16.3 / -2.20 / -1.68 / 1.31
H88521 / G protein-coupled receptor 48 / 11p14-p13 / -2.67 / -1.98 / 1.35
R41724 / Homo sapiens transcribed sequences / 1.49 / 2.06 / 1.38
H89664 / amyloid beta (A4) precursor-like protein 2 / 11q23-q25 / 1.49 / 2.06 / 1.38
N64009 / KIAA1199 protein / 15q / -2.38 / -1.71 / 1.39
R97788 / Ring-box 1 / 22q13.2 / -2.78 / -2.01 / 1.39 / enzyme
AA620404 / hypothetical protein LOC90850 / 16p13.3 / -2.51 / -1.78 / 1.41
AA496930 / reversion-inducing-cysteine-rich protein with kazal motifs / 9p13-p12 / -2.02 / -1.43 / 1.42 / enzyme inhibitor
R64066 / Homo sapiens transcribed sequences / -2.05 / -1.45 / 1.42
AA013260 / tribbles homolog 2 / 2p25.1 / 1.51 / 2.19 / 1.45 / enzyme
R39179 / Spir-2 protein / 16q24 / -2.10 / -1.44 / 1.45
N51068 / Homo sapiens cDNA FLJ42364 fis, clone UTERU2027591, moderately similar to Human / -2.01 / -1.38 / 1.46
AA608770 / Homo sapiens transcribed sequence / -2.19 / -1.49 / 1.47
W61116 / mitogen-activated protein kinase kinase kinase 14 / 17q21 / -2.02 / -1.32 / 1.53 / enzyme
AA187595 / Ring finger protein 3 / 4p16.3 / -2.25 / -1.47 / 1.53
AA447480 / ARG99 protein / 12p11.23 / -2.01 / -1.29 / 1.56
R07897 / EST / 1.34 / 2.11 / 1.57
AA609348 / KIAA1576 protein / 16q23.1 / -2.37 / -1.47 / 1.61 / enzyme
AA457501 / cytochrome b reductase 1 / 2q31.1 / -2.45 / -1.52 / 1.61
T98662 / ribosomal protein S25 / 11q23.3 / 1.52 / 2.47 / 1.62 / nucleic acid binding
AA058314 / lectin, galactoside-binding, soluble, 3 (galectin 3) / 14q21-q22 / 1.35 / 2.18 / 1.62 / ligand binding or carrier
AA450062 / prostate differentiation factor / 19p13.1-13.2 / 1.29 / 2.10 / 1.62
AA169724 / protein arginine N-methyltransferase 6 / 1p13.3 / 2.00 / 3.24 / 1.62 / enzyme
AA165208 / Homo sapiens transcribed sequences / -2.09 / -1.28 / 1.64
AA169807 / Homo sapiens cDNA FLJ42602 fis, clone BRACE3011271, moderately similar to Patch / 1.26 / 2.08 / 1.65
N21546 / topoisomerase (DNA) III alpha / 17p12-17p11.2 / 1.30 / 2.18 / 1.67 / enzyme
AA133566 / general transcription factor IIE, polypeptide 2, beta 34kDa / 8p21-p12 / 1.20 / 2.04 / 1.69 / nucleic acid binding
AA164712 / FLJ00166 protein / 3q27.2 / -2.34 / -1.38 / 1.70
AA453859 / alcohol dehydrogenase 5 (class III), chi polypeptide / 4q21-q25 / 1.22 / 2.09 / 1.71 / enzyme
AA401111 / glucose phosphate isomerase / 19q13.1 / 1.35 / 2.32 / 1.72 / enzyme
AA609304 / Homo sapiens transcribed sequence with weak similarity to protein ref:NP_060312 / -2.03 / -1.18 / 1.73
AA045481 / RAP2C, member of RAS oncogene family / Xq25 / 1.29 / 2.23 / 1.73 / enzyme
T56874 / UPF2 regulator of nonsense transcripts homolog (yeast) / 10p14-p13 / -2.07 / -1.20 / 1.73 / nucleic acid binding
W32523 / signal recognition particle 72kDa / 4q11 / -2.05 / -1.18 / 1.74
AA137266 / nuclear ubiquitous casein kinase and cyclin-dependent kinase substrate / 1q32.1 / 1.18 / 2.07 / 1.75
T53907 / coatomer protein complex, subunit beta 2 (beta prime) / 3q23 / -2.25 / -1.28 / 1.75 / signal transducer
AA443948 / C-terminal tensin-like / 17q21.2 / 1.15 / 2.01 / 1.76
AA457232 / transcriptional regulator protein / 17q25.3 / -2.08 / -1.18 / 1.76
AA608977 / Homo sapiens transcribed sequences / 1.22 / 2.14 / 1.76
R53940 / Homo sapiens transcribed sequences / 1.24 / 2.19 / 1.77
T68464 / hypothetical protein FLJ30596 / 5p13.2 / -2.67 / -1.50 / 1.78
R33030 / EST / 1.45 / 2.60 / 1.79
T98663 / proteasome (prosome, macropain) subunit, beta type, 2 / 1p34.2 / -2.40 / -1.34 / 1.79 / enzyme
AA521490 / limkain b1 / 16p13.13 / 1.46 / 2.63 / 1.80
AA598637 / chaperonin containing TCP1, subunit 4 (delta) / 2p15 / 1.13 / 2.05 / 1.81 / chaperone
H77772 / Homo sapiens transcribed sequence with weak similarity to protein ref:NP_060219 / 1.17 / 2.13 / 1.83
R34957 / EST / 1.14 / 2.10 / 1.84
AA521469 / GTP binding protein 1 / 22q13.1 / 1.28 / 2.36 / 1.84
N70122 / ATPase, H+ transporting, lysosomal V0 subunit a isoform 2 / 12q24.31 / -2.59 / -1.41 / 1.84
R76394 / protease, serine, 23 / 11q14.1 / -3.42 / -1.85 / 1.85 / enzyme
AA261796 / multiple endocrine neoplasia I / 11q13 / 1.41 / 2.62 / 1.85 / ligand binding or carrier
N51632 / peptidase (mitochondrial processing) alpha / 9q34.3 / -2.81 / -1.52 / 1.86 / enzyme
H11270 / mannosidase alpha class 2B member 2 / 4p16.2 / -2.01 / -1.07 / 1.87 / enzyme
T87324 / EST / 1.15 / 2.19 / 1.90
T64905 / paired-like homeodomain transcription factor 2 / 4q25-q27 / 1.06 / 2.01 / 1.90 / nucleic acid binding
AA083032 / cyclin G1 / 5q32-q34 / 1.16 / 2.21 / 1.91
AA504327 / EST / 1.25 / 2.39 / 1.92
T49530 / lipase, endothelial / 18q21.1 / 1.06 / 2.07 / 1.95 / enzyme
AA486919 / ribosomal protein L28 / 19q13.4 / 1.07 / 2.08 / 1.95 / nucleic acid binding
H29555 / Homo sapiens clone 25248 mRNA sequence / 1.16 / 2.27 / 1.96
R33353 / EST / 1.06 / 2.09 / 1.96
H99213 / Homo sapiens transcribed sequences / 1.35 / 2.65 / 1.97
AA610071 / Homo sapiens transcribed sequences / -2.48 / -1.25 / 1.98
AA456400 / adenylosuccinate lyase / 22q13.1 / 1.08 / 2.16 / 2.00 / enzyme
W31540 / KIAA1450 protein / 4q32.1 / -3.24 / -1.62 / 2.00
AA461424 / ephrin-B2 / 13q33 / -1.12 / 1.79 / 2.00 / signal transducer
AA451903 / RNA binding motif protein 9 / 22q13.1 / -1.48 / 1.36 / 2.01 / nucleic acid binding
T71879 / complement component 2 / 6p21.3 / -1.18 / 1.71 / 2.01 / defense/immunity protein
T47813 / macrophage stimulating 1 (hepatocyte growth factor-like) / 3p21 / -1.06 / 1.91 / 2.01 / defense/immunity protein
H61608 / gene trap ankyrin repeat / 4q21.1-q21.21 / -1.42 / 1.42 / 2.01
R99627 / chromosome 6 open reading frame 203 / 6q21 / 1.01 / 2.04 / 2.02
AA496121 / Homo sapiens transcribed sequences / -1.28 / 1.57 / 2.02
R13558 / activated leukocyte cell adhesion molecule / 3q13.1 / -1.17 / 1.72 / 2.02 / cell adhesion
H21071 / baculoviral IAP repeat-containing 1 / 5q13.1 / -1.79 / 1.13 / 2.02 / apoptosis inhibitor
H09245 / KIBRA protein / 5q35.1 / -1.76 / 1.15 / 2.02
R99918 / Homo sapiens transcribed sequences / 1.50 / 3.03 / 2.03
AA629904 / ADP-ribosylation factor related protein 1 / 20q13.3 / 1.22 / 2.49 / 2.04 / enzyme
H94554 / EST / -1.21 / 1.68 / 2.04
N29376 / myeloid cell nuclear differentiation antigen / 1q22 / -1.24 / 1.65 / 2.05 / nucleic acid binding
R26960 / peripheral myelin protein 22 / 17p12-p11.2 / 1.28 / 2.62 / 2.05
W04996 / periphilin 1 / 12q12 / 1.12 / 2.29 / 2.05
AA026631 / Ran GTPase activating protein 1 / 22q13 / -1.33 / 1.55 / 2.05 / enzyme activator
AA496541 / KIAA0317 gene product / 14q24.2 / -1.25 / 1.64 / 2.05 / enzyme
R70084 / EST / 1.13 / 2.33 / 2.05
R10541 / hypothetical protein FLJ11526 / 5q33.2 / -1.05 / 1.96 / 2.05
AA465017 / DnaJ (Hsp40) homolog, subfamily B, member 2 / 2q32-q34 / -1.19 / 1.73 / 2.06 / chaperone
AA454207 / abhydrolase domain containing 2 / 15q26.1 / -1.23 / 1.67 / 2.06 / enzyme
N47797 / Homo sapiens, clone IMAGE:5223057, mRNA / -1.18 / 1.76 / 2.07
T41207 / EST / -2.74 / -1.33 / 2.07
AA186804 / ERO1-like (S. cerevisiae) / 14q22.1 / -1.25 / 1.67 / 2.08
T83861 / EST / -2.26 / -1.08 / 2.08
AA446231 / Homo sapiens transcribed sequences / -1.68 / 1.24 / 2.08
N21032 / EST / -1.41 / 1.48 / 2.08
AA465366 / leukotriene A4 hydrolase / 12q22 / -2.03 / 1.03 / 2.09 / enzyme
AA459318 / tumor protein D52 / 8q21 / -1.08 / 1.94 / 2.09
R73539 / formin 2 / 1q43 / -1.71 / 1.22 / 2.09
N91302 / myeloid/lymphoid or mixed-lineage leukemia3 / 7q34-q36 / -1.21 / 1.74 / 2.10
R33335 / EST / 1.09 / 2.29 / 2.10
T91080 / EST / 2.19 / 4.62 / 2.11
H82706 / inhibitor of DNA binding 2, dominant negative helix-loop-helix protein / 2p25 / -1.56 / 1.36 / 2.11
N76587 / CDC42 binding protein kinase beta (DMPK-like) / 14q32.3 / -1.84 / 1.15 / 2.12 / enzyme
N95358 / myosin IB / 2q12-q34 / -1.64 / 1.29 / 2.13
H28984 / phosphatidylserine synthase 1 / 8q22 / -1.72 / 1.24 / 2.13
N95657 / cyclin fold protein 1 / 10p11.22 / -1.56 / 1.38 / 2.15
AA456931 / cytochrome c oxidase subunit VIc / 8q22-q23 / -1.49 / 1.45 / 2.15 / enzyme
N26823 / retinoblastoma binding protein 6 / 16p12.2 / -1.34 / 1.61 / 2.16 / ligand binding or carrier
N53616 / melanoma ubiquitous mutated protein / 19p13.3 / -1.07 / 2.02 / 2.16
H48793 / Homo sapiens transcribed sequences / -1.30 / 1.66 / 2.16
AA054287 / RNA binding motif protein 3 / Xp11.2 / -1.42 / 1.52 / 2.16 / nucleic acid binding
W94419 / UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase / 5q33.2 / -1.71 / 1.27 / 2.16
T62865 / aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) / 1p35.1-p36.23 / -1.36 / 1.59 / 2.16 / enzyme
AA427595 / SHB (Src homology 2 domain containing) adaptor protein B / 9p12-p11 / -1.62 / 1.33 / 2.17 / signal transducer
AA454005 / hypothetical LOC151256 / 2q33.2 / -1.10 / 1.97 / 2.17
R08790 / Homo sapiens transcribed sequences / -1.28 / 1.69 / 2.17
R44822 / phosphoribosyl pyrophosphate synthetase-associated protein 1 / 17q24-q25 / -1.33 / 1.63 / 2.17 / enzyme
AA033564 / DiGeorge syndrome critical region gene 6-like / -1.45 / 1.50 / 2.17
AA609783 / Homo sapiens mRNA; cDNA DKFZp586A0618 (from clone DKFZp586A0618) / -1.30 / 1.68 / 2.18
AA464962 / hypertension-related calcium-regulated gene / 8q24-qter / 1.37 / 3.01 / 2.19
AA431201 / hypothetical protein FLJ33915 / 12q24.33 / -1.23 / 1.79 / 2.20
H56424 / EST / 1.09 / 2.39 / 2.20
AA011281 / Homo sapiens transcribed sequences / -1.83 / 1.21 / 2.20
AA620477 / serine hydroxymethyltransferase 2 (mitochondrial) / 12q12-q14 / -1.32 / 1.68 / 2.21
T69732 / Homo sapiens transcribed sequences / 1.01 / 2.22 / 2.21
R63342 / EST / -1.41 / 1.57 / 2.21
AA172096 / endoplasmic reticulum thioredoxin superfamily member, 18 kDa / 1p32.3 / -1.66 / 1.33 / 2.22 / ligand binding or carrier
W94106 / casein kinase 1, epsilon / 22q13.1 / 1.11 / 2.48 / 2.24 / enzyme
AA598483 / Tax1 (human T-cell leukemia virus type I) binding protein 1 / 7p15 / -1.24 / 1.80 / 2.24 / apoptosis inhibitor
H79047 / insulin-like growth factor binding protein 2, 36kDa / 2q33-q34 / -1.46 / 1.53 / 2.24 / ligand binding or carrier
AA521422 / THAP domain containing 11 / 16q22.1 / -1.22 / 1.84 / 2.24 / nucleic acid binding
AA402855 / polymerase (DNA directed), beta / 8p11.2 / -1.40 / 1.60 / 2.24 / enzyme
AA457330 / calpain 6 / Xq23 / -1.13 / 1.98 / 2.24 / enzyme
H83178 / ubiquitin specific protease 49 / 6p21.1 / -1.38 / 1.63 / 2.24
N75745 / interleukin 2 receptor, gamma (severe combined immunodeficiency) / Xq13.1 / -1.14 / 1.97 / 2.24 / signal transducer
AA002007 / Homo sapiens mRNA; cDNA DKFZp564D193 (from clone DKFZp564D193) / -2.39 / -1.06 / 2.25
H46487 / mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase / 22q13.1 / -1.70 / 1.33 / 2.25 / enzyme
H81199 / hypothetical protein MGC2198 / 5q35.3 / -1.05 / 2.14 / 2.25
H48099 / KIAA1972 protein / 16q13 / -1.42 / 1.60 / 2.27
T67106 / G protein-coupled receptor 86 / 3q24 / -1.14 / 1.99 / 2.27
AA455481 / centromere protein B, 80kDa / 20p13 / -1.50 / 1.51 / 2.27 / nucleic acid binding
H56345 / EST / -2.23 / 1.02 / 2.28
R05336 / EST / -1.45 / 1.58 / 2.29
AA429856 / Homo sapiens transcribed sequences / -1.40 / 1.64 / 2.29
N35341 / similar to RIKEN cDNA 1810055D05 / 3q27.2 / -1.74 / 1.32 / 2.29
AA143436 / ras homolog gene family, member D / 11q14.3 / -1.18 / 1.94 / 2.30 / enzyme
R10185 / protein kinase, lysine deficient 1 / 12p13.3 / -1.71 / 1.35 / 2.30
AA007364 / EST / -1.74 / 1.33 / 2.31
R99167 / Homo sapiens transcribed sequences / -1.56 / 1.50 / 2.33
R68492 / Homo sapiens LOC145188 (LOC145188), mRNA / -1.38 / 1.70 / 2.33
W84714 / Homo sapiens transcribed sequences / -1.08 / 2.16 / 2.34
W55997 / F-box and leucine-rich repeat protein 11 / 11q13.1 / -1.26 / 1.86 / 2.34 / ligand binding or carrier
AA411876 / ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast) / 7q32 / -1.14 / 2.05 / 2.34 / enzyme
N57872 / alanine-glyoxylate aminotransferase (oxalosis I; hyperoxaluria I; glycolicacidur / 2q36-q37 / -1.18 / 2.00 / 2.36 / enzyme
T73468 / EST / 1.38 / 3.30 / 2.39
H11792 / splicing factor, arginine/serine-rich 10 (transformer 2 homolog, Drosophila) / 3q26.2-q27 / -1.60 / 1.50 / 2.39 / Nucleic acid binding
R11335 / hypothetical protein KIAA1991 / 11q13.3 / -1.35 / 1.78 / 2.41
W21482 / chromosome 1 open reading frame 38 / 1p35.3 / -1.10 / 2.19 / 2.42
H90225 / hypothetical protein MGC8974 / 1p33-p32.1 / -1.81 / 1.34 / 2.42
H60491 / EST / -1.38 / 1.75 / 2.42
AA262988 / brain-derived neurotrophic factor / 11p13 / -1.43 / 1.70 / 2.42 / signal transducer
AA443688 / GTP cyclohydrolase 1 (dopa-responsive dystonia) / 14q22.1-q22.2 / -1.77 / 1.37 / 2.42 / enzyme
AA192527 / fucosyltransferase 8 (alpha (1,6) fucosyltransferase) / 14q24.3 / -1.09 / 2.24 / 2.44
H15504 / annexin A7 / 10q21.1-q21.2 / -1.25 / 1.96 / 2.44 / anticoagulant
AA427667 / T cell receptor alpha locus / 14q11.2 / -1.08 / 2.26 / 2.45 / signal transducer
AA480995 / methylene tetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofol / 2p13.1 / -1.50 / 1.64 / 2.45 / enzyme
H50747 / Homo sapiens transcribed sequence with weak similarity to protein pir:JC5238 (H / -1.24 / 1.99 / 2.47
R00418 / EST / -1.27 / 1.95 / 2.47
T88698 / protein phosphatase 2, regulatory subunit B (B56), gamma isoform / 14q32 / 1.02 / 2.53 / 2.48
W03686 / Homo sapiens transcribed sequence with moderate similarity to protein ref:NP_060 / -1.21 / 2.07 / 2.49
N53169 / apolipoprotein C-III / 11q23.1-q23.2 / 1.09 / 2.71 / 2.49 / transporter
AA598840 / polyhomeotic-like 2 (Drosophila) / 1p34.3 / -1.13 / 2.25 / 2.53
AA406081 / eukaryotic translation initiation factor 4A, isoform 2 / 3q28 / -1.34 / 1.90 / 2.54 / Enzyme
H16454 / small nuclear ribonucleoprotein D1 polypeptide 16kDa / 18q11.2 / -1.50 / 1.70 / 2.55 / Nucleic acid binding
N66433 / KIAA1223 protein / 4q28.1 / -1.66 / 1.55 / 2.56
N48197 / Homo sapiens transcribed sequences / -1.75 / 1.47 / 2.57
AA448468 / EST / -2.05 / 1.27 / 2.59
AA427688 / protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform / 19q13.41 / -2.19 / 1.20 / 2.62 / Enzyme
M17886 / ribosomal protein, large, P1 / 15q22 / -1.29 / 2.04 / 2.63 / nucleic acid binding
AA398218 / Non-metastatic cells 3, protein expressed in / 16q13 / -1.31 / 2.01 / 2.63 / Enzyme
N55067 / RAD23 homolog B (S. cerevisiae) / 9q31.2 / 1.08 / 2.88 / 2.65 / nucleic acid binding
W85927 / EST / -2.82 / -1.06 / 2.66
W69379 / hypothetical protein FLJ25059 / 11p14.1 / -1.41 / 1.92 / 2.70 / Enzyme
AA187982 / KARP-1-binding protein / 1q44 / -1.06 / 2.57 / 2.71
AA425755 / deleted in lymphocytic leukemia, 1 / 13q14.3 / -1.94 / 1.42 / 2.74
R78725 / EST / -1.21 / 2.36 / 2.86
AA047340 / hypothetical protein from EUROIMAGE 1977056 / 15q22.33 / -1.45 / 1.99 / 2.88
W02483 / Homo sapiens transcribed sequence with moderate similarity to protein ref:NP_057 / -1.02 / 2.84 / 2.89
H95077 / Homo sapiens transcribed sequences / 1.00 / 2.88 / 2.89
H89664 / amyloid beta (A4) precursor-like protein 2 / 11q23-q25 / -1.48 / 1.97 / 2.91
AA464121 / myosin, light polypeptide 5, regulatory / 4p16.3 / -1.87 / 1.57 / 2.95 / ligand binding or carrier
R66006 / acyl-Coenzyme A dehydrogenase, long chain / 2q34-q35 / -1.10 / 2.70 / 2.98
H91631 / hypothetical protein MGC15416 / 16p13.3 / -2.11 / 1.47 / 3.10
AA460156 / EST / -1.88 / 1.67 / 3.14
H51765 / paternally expressed 10 / 7q21 / -1.36 / 2.35 / 3.19 / nucleic acid binding
H22856 / EST / -2.12 / 1.51 / 3.21
AA450037 / KIAA0033 protein / 11p15.3 / 1.05 / 3.50 / 3.32 / Transporter
AA521243 / mitochondrial ribosomal protein L19 / 2q11.1-q11.2 / -3.28 / 1.19 / 3.90 / structural protein
H53949 / EST / -1.09 / 3.61 / 3.92
W70234 / dipeptidylpeptidase 4 (CD26, adenosine deaminase complexing protein 2) / 2q24.3 / -1.55 / 2.57 / 4.00 / Enzyme
T63031 / nuclear receptor co-repressor 2 / 12q24 / -1.19 / 3.46 / 4.10
N52315 / chromosome 13 open reading frame 10 / 13q22.2 / -1.20 / 3.74 / 4.47
T48312 / endosulfine alpha / 1q21.3 / -2.08 / 2.33 / 4.85 / signal transducer
AA464979 / hypothetical protein FLJ21820 / 2p24.2 / -1.82 / 3.67 / 6.70 / Enzyme
AA454153 / hypothetical protein LOC149837 / 20p13 / -8.24 / 1.89 / 15.54
T2D: type 2 diabetes mellitus without nephropathy
T2DN: type 2 diabetes mellitus with nephropathy
C: controls without diabetes and nephropathy
Values indicate differential expression at p<0.05. Significant regulation indicated a 2-fold change between groups using a common error model and a modified z test. All 2-fold changes were statistically significant at p<0.05 after FDR correction for multiple comparisons.