2014 Hopkins C.A.R.E.S

Summer Program Symposium:
Celebrating 20 Years of the Summer Internship Program

July 30, 2014
Armstrong Medical Education Building

1:00-4:30 p.m.

Schedule

1:00- 1:50p.m. / Welcome
Keynote Speakers:
Roger H. Reeves, PhD
Rajini Rao, PhD
Recognition of 20 years of the Summer Internship Program
AMEB, 1st Floor Auditorium
2:00- 2:55p.m. / Poster Session 1
AMEB, 2nd Floor Lobby
SSSP, MERIT, Odd Numbers
2:00- 3:55p.m. / Oral Presentations
AMEB, 1st Floor Auditoriums
3:00-3:55p.m. / Poster Session 2
AMEB, 2nd Floor
P-STAR, SURE, Even Numbers
4:00- 4:30p.m. / Closing: Roy Ziegelstein, M.D., Vice Dean for Education
Outstanding Students Awards
AMEB, 1st Floor Auditorium
Presentation of Certificates
AMEB, 1st Floor Lobby

Keynote Speakers

Roger H. Reeves, PhD

Dr. Roger Reeves is a professor of physiology at the Johns Hopkins University School of Medicine. Dr. Reeves is also on faculty at the McKusick-Nathans Institute for Genetic Medicine. Dr. Reeves received his B.S. from Bowling Green State University in 1975 and his Ph.D. from the University of Maryland in 1983. His postdoctoral work took place at Johns Hopkins University and he joined the faculty in 1983.

He has studied various aspects of Down syndrome for the last 25 years. He is currently the co-Director of the Down Syndrome Cognition Project, whose goal is to develop precise, sensitive and quantitative tests for cognitive problems in DS, and to correlate the overall impact with genetic factors that may contribute to a better or worse outcome. Dr. Reeves and his lab recently demonstrated a possible drug to normalize cerebellar hypoplasia which has unexpected positive consequences on learning and memory in a mouse model of DS.

Among other honors, Dr. Reeves was awarded the Sisley-Lejeune Award for Translational Research in Intellectual Disabilities in 2012.

Rajini Rao, PhD

Rajini Rao is Professor of Physiology at the Institute for Basic Biomedical Research of the Johns Hopkins University School of Medicine. She received her PhD in Biochemistry in 1988 from the University of Rochester. Following postdoctoral training in Genetics at Yale University, she was recruited to Johns Hopkins in 1993, rising through the ranks to become Professor in 2004. Her research specialty is to understand how transport of ions across cell membranes relates to human health and disease.Her laboratory was the first to discover the endosomal Na+/H+ exchangers (eNHE) and recognize them as distinct from those at the plasma membrane. These transporters have now been implicated in a range of neurological disorders including autism, attention deficit hyperactivity disorder, epilepsy, mental disability and Christianson’s syndrome. Currently, Dr. Rao combines the use of yeast and neurobiological models to determine how mutations in eNHE lead to neurological disease.

Dr. Rao's academic activities are divided between education, mentoring and research. As the Director of the Graduate Program in Cellular & Molecular Medicine, she oversees a multi-departmental training program with a focus on translational research that includes approximately 130 faculty mentors and 150 graduate students (Ph.D., M.D. /Ph.D. and D.V.M/Ph.D.). She is also a faculty mentor in other graduate programs at the School of Medicine (Biochemistry, Cell & Molecular Biology, and Cellular & Molecular Physiology) where she teaches graduate and medical students. Dr. Rao plays an active role in advocating for women and minority groups in academia. She chairs the Committee on Professional Opportunities for Women at the Biophysical Society, where she has assumed multiple leadership roles.

2014 Hopkins C.A.R.E.S. Summer Programs

Biophysics Research for Baltimore Teens (BRBT):

Biophysics for Baltimore Teens (BRBT) gives Baltimore City public school teens an opportunity to learn laboratory skills for basic biomedical research through a paid 8-week internship. The interns’ exposure to laboratory research will begin with classroom instruction and instructor-supervised laboratory sessions. Promising, interested students will be invited back for a second summer internship of research in an active biophysics research lab. BRBT is offered through the Johns Hopkins Program in Molecular Biophysics (PMB) and PMB graduate students on both campuses will mentor BRBT interns.

Center Scholars Program (CSP):

The Center Scholars Program, developed by CTY and Dr. Andrew Feinberg’s Center for Excellence in Genome Science (CEGS), is designed to encourage CTY qualified, historically underrepresented minority students to explore careers in scientific research, particularly the field of genomics.

Diversity and Academic Advancement Summer Institute (DAASI):

The Diversity and Academic Advancement Institute (DAASI) is a partnership between Johns Hopkins School of Medicine Office for Student Diversity and Thread (formerly the Incentive Mentoring Program, IMP). The goals are to three fold: (1) Academic Assistance: Provide a comprehensive, engaging curriculum to bolster participants’ academic self-confidence and capabilities; (2) Service, Life Skills, and Team Work: Create opportunities for participants to learn important life and professional skills through work opportunities and service learning experiences; and (3) Visualizing Success: Expose them to science and health educational pathways so that they may visualize the possibility of pursuing careers in science.

Institute for NanoBiotechnology Research Experience for Undergraduates (INBT):

The Institute for NanoBiotechnology at Johns Hopkins University offers undergraduate students from colleges and universities around the country a chance to participate in research projects in the exciting and rapidly growing area of NanoBiotechnology, a place where biology, medicine, and nanotech meet. Our goal is to promote the interest and completion of a PhD. We provide students with a graduate-level research experience for 10 weeks, where the student is exposed to cutting edge research lab, professional development seminars, and various academic experiences.

The Johns Hopkins Internship in Brain Science Program (JHIBS): Project Pipeline Baltimore: The long-term goal of the JHIBS program is to significantly increase the pool of qualified under-represented professional candidates from Baltimore in the neurosciences and mental health medicine through an eight-week summer research and enrichment experience that targets high school juniors and seniors. The program will provide the necessary exposure, knowledge, and career-long mentoring, to help propel students toward a trajectory as a STEM professional. The program has been in existence for seven years funded by the Cohen Foundation and jointly this year with a grant from the National Institutes of Mental Health

Medical Education Initiative for Teens (MERIT):

MERIT aims to inspire students fromBaltimore Cityto pursue careers in health care by preparing them for the multiple challenges that lie ahead. MERIT Scholars learn the importance of leadership, cooperation, and reflection while cultivating a deep understanding of their individual roles in solving America’s health disparities through a holistic approach including weekly Saturday sessions, mentoring, and summer internships. MERIT Scholars leave the program with an intense passion for eliminating health inequalities, a clear vision of how to become a health care professional, a toolkit of knowledge and skills necessary for achieving graduate degrees, and a close-knit community of peers and mentors who will continue to work collaboratively toward their collective goal of becoming agents of positive change in their communities.

Psychiatry Summer Training and Research Program (P-STAR):

The Psychiatry Summer Training and Research (P-STAR) program offers undergraduates interested in Behavioral and Biological Sciences the opportunity to work for ten weeks under the guidance of a faculty member at Johns Hopkins Medicine. Through one on one work with a faculty mentor, students gain hands on experience in academic research and clinical environments. Students will have participate in many activities such as conducting research alongside leading principal investigators, shadowing physicians at the Johns Hopkins Hospital Psychiatry Outpatient clinic and attending clinical teaching rounds on units. Students also will participate in research seminars, weekly-journal clubs, and personal lunchtime discussions with doctors involved in cutting-edge research. We will have students work in both a laboratory and clinical setting to provide in-depth exposure to Translational Psychiatry, especially that on schizophrenia and related disorders.

Pulmonary and Critical Care Medicine Summer Internship Program (PCCM):

The Division of Pulmonary and Critical Care Medicine hosts undergraduate students each summer as part of an NIH funded program to enhance diversity in biomedical sciences. Students from around the United States and Puerto Rico join faculty for a ten week, research focused experience that extends from Memorial Day weekend through the first week of August. Students are matched with mentors based on their interests. Students work on specific research projects under the supervision of their mentor. Projects span a broad range of research, from the basic science of endothelial or epithelial cell biology to asthma epidemiology. In addition to the research experience, students participate in a weekly journal club, during which they present primary research articles to their peers and members of the faculty. Students also attend a seminar series featuring faculty members from Johns Hopkins and the NIH. This forum provides students with the opportunity to interact with faculty members and hear different perspectives on issues related to career development. Students interested in clinical medicine are given the opportunity to “round” with the Johns Hopkins Medicine residents, providing a glimpse of life in clinical medicine as a resident at an academic institution.

Stanley Summer Scholars Program (SSSP):

The goal of the Stanley Summer Scholars Program of the Stanley Division of Developmental Neurovirology, Department of Pediatrics, is to foster enthusiasm for the study of the etiology, pathology, immunology, prevention and treatment of serious psychiatric diseases such as schizophrenia and bipolar disorder. By offering students the opportunity to gain laboratory experience while working closely with a mentor from the Stanley Division, we hope to encourage the pursuit of careers in basic, translational or clinical research focusing on major mental illnesses. Research performed in the Stanley Division is interdisciplinary and projects are available in a number of fields including molecular biology, immunology, virology, parasitology, cell culture, animal behavior and neuroscience. Program activities include weekly lectures by faculty & postdoctoral fellows describing different aspects of mental illness research, weekly lab meetings, attendance of Schizophrenia and Mood Disorders Rounds in the Department of Psychiatry and a poster/oral presentation by students at the end of the summer.

Summer Internship Program Basic Science Institute (SIP/BSI):

The Summer Internship Program (SIP) provides intensive experience in research laboratories to college students of diverse backgrounds, including underrepresented minority students, students from economically disadvantaged or underserved backgrounds, and students with disabilities. The purpose of this exposure to biomedical and/or public health research is to encourage students to consider PhD research careers in science, medicine and public health.

Summer Urological Research Experience (SURE):

The Summer Urological Research Experience (SURE), is an undergraduate research internship that provide students an opportunity to move beyond the classroom learning experience to gather the knowledge and skills needed to pursue a career founded in the biomedical sciences. SURE is designed to provide a one of a kind research experience to students in the hope to foster an interest in students in the areas of urological and cancer research.Hosted by the James Buchanan Brady Urological Institute, SURE provides a unique opportunity for young scientists to work alongside some of the leading researchers in urology and oncology while utilizing a broad range of techniques and methodologies. Utilizing the Department’s translational research program, young researchers are able to see how research done at the bench can be translated into patient care. In addition to the vast amount of research experience that is gained during the program, students also attend numerous lectures and seminars given by the University's and theDepartment's numerous gifted faculty that will prepare them for the paradigms, problems, and technologies in biomedical research.

Oral Presentations

Auditorium East

Session 1

2:00-2:10 / MERIT / Beverly Danh / Asthma
2:10-2:20 / MERIT / Kahlid Fowlkes / HIV/AIDS
2:20-2:30 / BRBT / Joshua Garza / BRBT Science Boot camp
2:30-2:40 / MERIT / Christiona Harris / Teen Pregnancy
2:40-2:50 / Basic Science / Alexandriya Emonds / Motor Adaptation in Split-Belt Treadmill Walking

Session 2

3:00-3:10 / MERIT / Karen Hernandez / Alcohol/Drug Abuse
3:10-3:20 / MERIT / Lidia Hernandez / Suicide
3:20-3:30 / INBT / Elliot MacKrell / Immunomodulation via nanoparticle-mediated hyperthermia and ionizing radiation to enhance resistance against distal tumors
3:30-3:40 / PCCM / Stephan Maman / Mechanisms Involved in Hypoxia-inducible Factor 1 Dependent Upregulation of Aquaporin 1
3:40-3:50 / Basic Science / Maxine Garcia / Alterations in Striatal Volume in the Deer Mouse Model of Primary Stereotypy

Auditorium West

Session 1

2:00-2:10 / INBT / Florencia Velez-Cortes / Programmed actuation of photopatterned hydrogel by DNA-crosslink
2:10-2:20 / MERIT / Savannah Tripp / Heart Disease
2:20-2:30 / MERIT / Precious Tatum / Lupus
2:30-2:40 / Basic Science / Emily Robitschek / Mustering troops for the body's war on cancer: polymeric protein complexes to activate the adaptive immune response
2:40-2:50 / MERIT / Jamia Marriott / Depression

Session 2

3:00-3:10 / MERIT / Taylar Reed / Schizophrenia
3:15-3:25 / BRBT / Candice Jennings / BRBT
3:30-3:40 / MERIT / Joshua Neal / Eating Disorders
3:45-3:55 / Basic Science / Brandi Temple / Preclinical studies using bioactive compounds to develop novel chemoprevention strategies for breast cancer

Poster Presentations

Session 1 (2:00-2:50)

# / Name / Program / Title
1 / Esteban Urias / BRBT / BRBT Science Boot camp
3 / Aviva Braier / CSP / DNA Methylation in Response to Estrogen Treatment in Postpartum Depression Biomarkers
5 / Sophia Caldera / CSP / Methylation and Genetic Variation of the IL-6 Receptor Associated with Age-Related Inflammation
7 / Adriana Gonzalez / CSP / Bioinformatic Analysis and Computational Modeling of miRNA Regulatory Behavior
9 / Chris Hadinono / CSP / Building a High Throughput Bioreactor to Culture Induced Pluripotent Stem Cells into Cerebral Organoids
11 / Brandon Lau / CSP
13 / Gabriela Memba / CSP / The Effects of Leptin on Locomotor Activity, Feeding Behavior, Motivation, in OB/OB Mice
15 / Savannah Burrell / DAASI / Organ Donations
17 / Shaniya Dwight / DAASI / Colorectal Cancer
19 / Diamond Eveline / DAASI / Tissue Engineering
21 / Tamiaya Ford / DAASI / Orthopedic Surgery
23 / Donte Godwin / DAASI / Security at Johns Hopkins
25 / Tyriq Lee / DAASI / Cell Tissue Engineering
27 / Desirae McKoy / DAASI / David Rubenstein Children's Health Center
29 / Devin Mobley / DAASI / Heart Cells
31 / Sierra Atwater / INBT / The Synergistic Effects of Interleukin-6 (IL-6) and Interleukin-8 (IL-8) on Cancer Cell Motility