Patient and Public Preferences for Health States Associated with AMD

Selected Journal Articles Year 2 (2012-2013)

2013

Multi-cycle recovery of lactoferrin and lactoperoxidase from crude whey using fimbriated high-capacity magnetic cation exchangers and a novel ‘rotor-stator’ high-gradient magnetic separator

Brown, G.N., Müller, C., Theodosiou, E., Franzreb, M., & Thomas, O.R.T. (2013) Biotechnol Bioeng, 110(6), 1714 –1725. doi: 10.1002/bit.24842.

Patient and public preferences for health states associated with AMD

Butt, T., Dunbar, H. M., Morris, S., Orr, S., & Rubin, G. S. (2013) Optom Vis Sci, 90(8), 855-60. doi:10.1097/OPX.0b013e3182962318.

Innovation in biopharmaceutical manufacture
Davidson, A., Farid, S.S. (2013) Bioprocess Int. 11(9) (in press)

Continuous protein purification using functionalized magnetic nanoparticles and aqueous micellar two-phase systems

Fischer, I., Gärtner, Hsu, C-C., Müller, C., Overton, T.W., Thomas, O.R.T., & Franzreb, M. (2013) J Chromatogr A, 1305, 7-16. doi: 10.1016/j.chroma.2013.06.011

Chromatography modelling to describe protein adsorption at bead level

Gerontas, S., Shapiro, M.S., Bracewell, D.G.(2013) J Chromatogr A, 1284, 44-52. doi: 10.1016/j.chroma.2013.01.102

FpFs as IgG mimetics

Khalili, H., Godwin, A., Choi, J. W., Lever, R., Khaw, P. T., & Brocchini, S. (2013). Bioconj Chem. doi: 10.1021/bc400246z [Epub ahead of print]

Identifying analytics for high throughput bioprocess development studies

Konstantinidis S., Kong S., & Titchener-Hooker N. (2013). Biotechnol Bioeng, 110 (7), 1924–1935, doi: 10.1002/bit.24850

An ultra scale-down characterization of low shear stress primary recovery stages to enhance selectivity of fusion protein recovery from its molecular variants

Lau E.C., Kong S., McNulty S., Entwisle C., Mcilgorm A., Dalton K.A., Hoare M. (2013). Biotechnol Bioeng, 110 (7), 1973–1983. doi: 10.1002/bit.24865

Designing cost-effective biopharmaceutical facilities using mixed-integer optimization
Liu, S., Simaria, A.S., Farid, S. S., & Papageorgiou, L. (2013). Biotechnol Prog. doi: 10.1002/btpr.1795 [Epub ahead of print]

Mixed integer optimisation of antibody purification processes
Liu, S., Simaria, A.S., Farid, S.S. and Papageorgiou, L.G. (2013) Computer Aided Chemical Engineering, 32: 157–162. doi 10.1016/B978-0-444-63234-0.50027-0

Multiobjective optimisation of production, distribution and capacity planning of global supply chains in the process industry

Liu, S., & Papageorgiou, L. G. (2013). OMEGA International Journal of Management Science, 41, 369-382. doi:10.1016/j.omega.2012.03.007

Preparation and characterisation of amphotericin B-copolymer complex for the treatment of leishmaniasis

Mohamed-Ahmed, A. H. A., Les, K. A., Brocchini, S., & Croft, S. L. (2013). Polym Chem, 4 (3), 584-591. doi:10.1039/c2py20425h

Noncovalent complexation of amphotericin-B with Poly (α-glutamic acid)

Mohamed-Ahmed, A. H., Les, K. A., Seifert, K., Croft, S. L., & Brocchini, S. (2013). Mol Pharm, 10 (3), 940-950. doi:10.1021/mp300339p

Anti-leishmanial activity, uptake and biodistribution of an amphotericin B - poly(α-glutamic acid) complex

Mohamed-Ahmed, A. H., Seifert, K., Yardley, V., Burrell-Saward, H., Brocchini, S., & Croft, S. L. (2013). Antimicrob Agents Chemother. doi:10.1128/AAC.02343-12

Integrated system for temperature-controlled FPLC comprising improved copolymer modified beaded agarose adsorbents and a travelling cooling zone reactor (TCZR) arrangement

Müller, T.K.H., Cao, P., Ewert, S., Wohlgemuth, J., Liu, H., Willett, T.C., Theodosiou, E., Thomas, O.R.T. & Franzreb, M. (2013) J Chromatogr A, 1285, 97-109. doi: 10.1016/j.chroma.2013.02.025.

In situ modification of chromatography adsorbents using cold atmospheric pressure plasmas
Olszewski, P., Willett, T.C., Theodosiou, E., Thomas, O.R.T., & Walsh, J. L. (2013) Appl Phys Lett, 102, 202104-1 – 20104-5. doi: 10.1063/1.4807931.

Characterisation of ilomastat for prolonged ocular drug release

Parkinson, G., Gaisford, S., Ru, Q., Lockwood, A., Khalili, A., Brocchini, S., & Sheridan, R. (2013). AAPS PharmSciTech, 13 (4), 1063-1072. doi:10.1208/s12249-012-9832-1

A case-study investigating physico-chemical characteristics that control the function of a liposomal adjuvant
Perrie, Y., Kastner, E., Kaur, R., & Wilkinson, A. (2013). Vaccines & Immunotherapeutics, 9, 1374 – 1381. doi:10.4161/hv.24694

Optimising the design and operation of semi-continuous affinity chromatography for clinical and commercial manufacture

Pollock, J., Bolton, G., Coffman, J., Ho, S. V., Bracewell, D. G., & Farid, S. S. (2013). J Chromatogr A, 1284, 17-27. doi:10.1016/j.chroma.2013.01.082

Fed-batch and perfusion culture processes: economic, environmental, and operational feasibility under uncertainty

Pollock, J., Ho, S. V., & Farid, S. S. (2013). Biotechnol Bioeng, 110 (1), 206-219. doi:10.1002/bit.24608

The solution structure of rabbit IgG accounts for its interactions with the Fc receptor and complement C1q and its conformational stability

Rayner, L. E., Kadkhodayi-Kholghi, N., Heenan, R. K., Gor, J., Dalby, P. A., & Perkins, S. J. (2013). J Mol Biol, 425 (3), 506-523. doi:10.1016/j.jmb.2012.11.019

Optically induced thermal gradients for protein characterization in nanolitre-scale samples in microfluidic devices

Sagar, D. M., Aoudjane, S., Gaudet, M., Aeppli, G., & Dalby, P. A. (2013). Sci Rep, 3, 1-6. doi:10.1038/srep02130

Allogeneic cell therapy bioprocess economics and optimization: single-use cell expansion technologies
Simaria, A.S., Hassan, S., Varadaraju, H., Rowley, J, Warren, K., Vanek, P., & Farid, S. S. (2013). Biotechnol Bioeng. doi:10.1002/bit.25008 [Epub ahead of print]

Cost-effectiveness of single-use technologies for commercial cell therapy manufacture

Simaria, A.S., Hassan, S., & Farid, S.S. (2013). American Pharmaceutical Review, 16, 40-45.

Integration of stochastic simulation with multivariate analysis: short-term facility fit prediction

Stonier, A., Pain, D., Westlake, A., Hutchinson, N., Thornhill, N. F., & Farid, S. S. (2013). Biotechnol Prog, 29 (2), 368-377. doi:10.1002/btpr.1678

Systematic review of drug administration costs and implications for biopharmaceutical manufacturing

Tetteh E & Morris S. (2013) Appl Hlth Econ Hlth Policy.doiI: 10.1007/s40258-013-0045-x [Epub ahead of print]

Measuring current and future cost of skin cancer in England

Vallejo-Torres L., Morris S., Kinge J.M., Poirier V., & Verne J (2013) J Public Hlth. doi: 10.1093/pubmed/fdt032 [Epub ahead of print]

Income-related inequity in healthcare utilisation among individuals with cardiovascular disease in England-accounting for vertical inequity

Vallejo-Torres, L., & Morris, S. (2013). Health Econ, 22 (5), 533-553. doi:10.1002/hec.2821

Prediction of biopharmaceutical facility fit issues using decision tree analysis
Yang Y., Farid S.S., Thornhill N.F. (2013)Comp Aided Chem Eng, 32, 61-66. doi: 10.1016/B978-0-444-63234-0.50011-7

Mathematical programming formulations for non-smooth and non-convex electricity dispatch problems

Yang, L., Fraga, E. S., & Papageorgiou, L. G. (2013). Electric Power Systems Res, 95, 302-308. doi.org/10.1016/j.epsr.2012.09.015

2012

A spatially-explicit, multi-period milp modelling framework for the optimal design of a hybrid biofuel supply chain

Akgul, O., Shah, N., & Papageorgiou, L. G. (2012) Comp Aided Chem Eng, 31.

Efficient discovery of chromatography equipment sizing strategies for antibody purification processes using evolutionary computing

Allmendinger, R., Simaria, A. S., & Farid, S. S. (2012). Lecture Notes in Computer Science, 7492, 468-477. doi:10.1007/978-3-642-32964-7_47

A mathematical programming approach to community structure detection in complex networks

Bennett, L., Liu, S., Papageorgiou, L. G., & Tsoka, S. (2012). Comp Aided Chem Eng, 31, 1387 – 1391.

Comparative binding of disulfide-bridged PEG-Fabs

Brocchini, S., Khalili, H., Godwin, A., Choi, J. W., & Lever, R. (2012). Bioconjug Chem. 23(11), 2262-77. doi: 10.1021/bc300372r

Automated methods for accurate determination of the critical velocity of packed bed chromatography

Chang, Y., Gerontas, S., & Titchener-Hooker, N.J. (2012) Biotechnol Prog, 28(3), 740-5. doi:10.1002/btpr.1544

Site-specific PEGylation at histidine tags

Cong, Y., Pawlisz, E., Bryant, P., Balan, S., Laurine, E., Tommasi, R., Singh, R., Dubey, S., Peciak, K., Bird, M., Sivasankar, A., Swierkosz, J., Muroni, M., Heidelberger, S., Farys, M., Khayrzad, F., Edwards, J., Badescu, G., Hodgson, I., Heise, C., Somavarapu, S., Liddell, J., Powell, K., Zloh, M., Choi, J.-W., Godwin, A., & Brocchini, S. (2012) Bioconjug Chem, 23 (2), 248–263. doi:10.1021/bc200530x

Evaluating and visualising the cost-effectiveness and robustness of biopharmaceutical manufacturing strategies
Farid, S.S. (2012) in Subramanian, G. (ed.) Biopharmaceutical Production Technology, Wiley VCH, Ch 22, 717-742. doi:10.1002/9783527653096.ch22

Use of design of experiment and microscale down strategies in formulation and cycle development for lyophilization

Grant, Y., Dalby, P. A., & Matejtschuk, P. (2012). American Pharmaceutical Review, 15 (2)

Freeze drying formulation using microscale and design of experiment approaches: a case study using granulocyte colony-stimulating factor
Grant, Y., Matejtschuk, P., Bird, C., Wadhwa, M., & Dalby, P.A.(2012) Biotech Lett, 34 (4), 641– 648. doi:10.1007/s10529-011-0822-2

Target fishing and docking studies of the novel derivatives of aryl-aminopyridines with potential anticancer activity
Erić, S., Ke, S., Barata T., Solmajer, T., Antić Stanković, J., Juranić, Z., Savić, V., & Zloh, M. (2012) Bioorg Med Chem, 20(17), 5220-8. doi:10.1016/j.bmc.2012.06.051

Strategic assay selection for analytics in high throughput process development: case studies for downstream processing of monoclonal antibodies

Konstantinidis, S., Kong, S., Chhatre, S., Velayudhan, A., Heldin, E., & Titchener-Hooker, N.J. (2012). Biotechnol J, 7 (10), 1256-1268. doi: 10.1002/biot.201100476

The hybrid experimental simplex algorithm – An alternative method for ‘sweet spot’ identification in early bioprocess development: Case studies in ion exchange chromatography
Konstantinidis, S., Chhatre, S., Velayudhan, A., Heldin, E., & Titchener-Hooker, N. (2012) Anal Chim Acta, 743C, 19-32. doi:10.1016/ j.aca.2012.06.039

Investigating the use of column inserts to achieve better chromatographic bed support

Lan, T., Gerontas, S., Smith, G. R., Langdon, J., Ward, J. M., & Titchener-Hooker, N. J. (2012). Biotechnol Prog, 28 (5), 1285-1291. doi:10.1002/btpr.1597

A model predictive control approach for multi-echelon supply chain management with price elasticity of demand

Liu, S., Shah, N., & Papageorgiou, L. G. (2012). AIChE Journal, 58, 369-382

A mathematical programming approach for optimal design of distributed energy systems at the neighbourhood level

Mehleri, E. D., Sarimveis, H., Markatos, N. C., & Papageorgiou, L. G. (2012). Energy, 42, 96-104.

On behalf of the EUROACTION Study Group. Cost-effectiveness of a European preventive cardiology programme in primary care: a Markov modelling approach

Mistry H., Morris S. Dyer M., Kotseva K., Wood D., Buxton M. (2012) BMJ Open, 2, e001029. doi: 10.1136/bmjopen-2012-001029

Utilisation of key descriptors from protein sequence data to aid bioprocess route selection

O'Malley, C. J., Montague, G. A., Martin, E. B., Liddell, J. M., Kara, B., & Titchener-Hooker, N. J. (2012). Food Bioprod Proc 90(4) 755-761, doi:10.1016/j.fbp.2012.01.005

A generic hierarchical screening method for the analysis of microscale refolds using an automated robotic platform

Ordidge, G. C., Mannall, G., Liddell, J., Dalby, P. A., & Micheletti, M. (2012). Biotechnol Prog, 28 (2), 435-444. doi:10.1002/btpr.1502

Characterisation of Ilomastat for Prolonged Ocular Drug Release
Parkinson G, Gaisford S, Ru Q, Lockwood A, Khalili A, Sheridan R, Khaw PT, Brocchini S, Fadda HM. AAPS PharmSciTech 2012,13(4):1063-72. doi:10.1002/btpr.1597

Rational substrate and enzyme engineering of transketolase for aromatics

Payongsri, P., Steadman, D., Strafford, J., MacMurray, A., Hailes, H. C., & Dalby, P. A. (2012). Org Biomol Chem, 10 (45), 9021-9029. doi:10.1039/c2ob25751c

Computer-aided design and evaluation of batch and continuous multi-mode biopharmaceutical manufacturing processes

Pollock, J., Ho, S. V., & Farid, S. S. (2012). Comp Aided Chem Eng, 30, 487-491. doi: 10.1016/B978-0-444-59519-5.50098-8

Optimal synthesis of chromatographic trains for downstream protein processing
Polykarpou, E. M., Dalby, P. A., & Papageorgiou, L. G. (2012). Biotechnol Prog, 27(6) 1653-1660. doi:10.1002/btpr.670

A novel efficient optimisation system for purification process synthesis

Polykarpou, E. M., Dalby, P. A., & Papageorgiou, L. G. (2012). Biochem Eng J, 67, 186-193. doi:10.1016/j.bej.2012.06.012

Production planning of batch and semi-continuous bioprocesses across multiple biopharmaceutical facilities

Siganporia, C., Ghosh, S., Daszkowski, T., Papageorgiou, L. G., & Farid, S. (2012). Comp Aided Chem Eng, 30, 377 – 381. doi:10.1016/B978-0-444-59519-5.50076-9

A multi-level metaheuristic algorithm to optimise antibody purification processes at the bioprocess-business interface

Simaria, AS, Turner, R, & Farid, S. S. (2012). Biochem Eng J, 69, 144-154. doi:10.1016/j.bej.2012.08.013

Decisional tool to assess current and future process robustness in an antibody purification facility

Stonier, A., Simaria, A. S., Smith, M., & Farid, S. S. (2012). Biotechnol Prog, 28 (4), 1019-1028. doi:10.1002/btpr.1569

Directed evolution to re-adapt a co-evolved network within an enzyme

Strafford, J., Payongsri, P., Hibbert, E. G., Morris, P., Batth, S. S., Steadman, D., Dalby, P. A. (2012). J Biotechnol, 157 (1), 237-245. doi:10.1016/j.jbiotec.2011.11.017