Table S1 ORF analysis of the vB_Sru IME250 genome
ORF / Top BLAST hita / % identityb (aa) / E valuec / Accession No.1 / baseplate hub subunit [Klebsiella phage 0507-KN2-1] / 191/216(88%) / 2e-140 / YP_008531972.1
2 / hypothetical protein [Klebsiella phage 0507-KN2-1] / 131/159(82%) / 7e-98 / YP_008531973.1
3 / hypothetical protein [Klebsiella phage 0507-KN2-1] / 146/162(90%) / 5e-106 / YP_008531974.1
4 / putative Holliday junction resolvase RuvC [Klebsiella phage 0507-KN2-1] / 184/202(91%) / 2e-138 / YP_008531975.1
5 / putative membrane protein [Salmonella phage vB_SalM_PM10] / 69/98(70%) / 3e-42 / YP_009293260.1
6 / Regulatory protein, FmdB family [Salmonella phage ViI] / 39/41(95%) / 9e-19 / YP_004327441.1
7 / Gp33 late promoter transcription factor [Salmonella phage ViI] / 66/80(83%) / 3e-42 / YP_004327440.1
8 / hypothetical protein [Shigella phage Ag3] / 51/79(65%) / 3e-33 / YP_003358554.1
9 / single stranded DNA-binding protein [Klebsiella phage 0507-KN2-1] / 311/349(89%) / 0.0 / YP_008531976.1
10 / hypothetical protein [Klebsiella phage 0507-KN2-1] / 37/60(62%) / 3e-20 / YP_008531977.1
11 / baseplate tail tube [Klebsiella phage 0507-KN2-1] / 284/292(97%) / 0.0 / YP_008531978.1
12 / DNA end protector protein [Klebsiella phage 0507-KN2-1] / 229/235(97%) / 5e-172 / YP_008531979.1
13 / hypothetical protein [Klebsiella phage 0507-KN2-1] / 132/245(54%) / 1e-84 / YP_008531980.1
14 / hypothetical protein [Klebsiella phage 0507-KN2-1] / 72/102(71%) / 3e-46 / YP_008531981.1
15 / hypothetical protein [Klebsiella phage 0507-KN2-1] / 247/308(80%) / 7e-175 / YP_008531982.1
16 / hypothetical protein [Klebsiella phage 0507-KN2-1] / 215/220(98%) / 1e-160 / YP_008531983.1
17 / Thymidylate synthase [Salmonella phage ViI] / 287/347(83%) / 0.0 / YP_004327431.1
18 / hypothetical protein [Klebsiella phage 0507-KN2-1] / 184/187(98%) / 3e-135 / YP_008531985.1
19 / putative dUTP diphosphatase [Klebsiella phage 0507-KN2-1] / 154/184(84%) / 6e-115 / YP_008531986.1
20 / hypothetical protein [Klebsiella phage 0507-KN2-1] / 139/143(97%) / 1e-98 / YP_008531987.1
21 / recA bacterial DNA recombination family protein [Dickeya phage phiD3] / 349/361(97%) / 0.0 / AIM51312.1
22 / hypothetical protein [Klebsiella phage 0507-KN2-1] / 35/39(90%) / 1e-15 / YP_008531989.1
ORF / Top BLAST hita / % identityb (aa) / E valuec / Accession No.
23 / DNA primase-helicase subunit [Klebsiella phage 0507-KN2-1] / 452/475(95%) / 0.0 / YP_008531990.1
24 / hypothetical protein [Klebsiella phage 0507-KN2-1] / 92/111(83%) / 3e-66 / YP_008531991.1
25 / hypothetical protein [Klebsiella phage 0507-KN2-1] / 96/100(96%) / 1e-65 / YP_008531992.1
26 / conserved hypothetical protein [Klebsiella phage 0507-KN2-1] / 371/397(93%) / 0.0 / YP_008531993.1
27 / No hit
28 / hypothetical protein [Salmonella phage vB_SalM_SJ3] / 76/110(69%) / 1e-49 / YP_009030371.1
29 / No hit
30 / putative uncharacterised protein [Salmonella phage ViI] / 90/113(80%) / 5e-65 / YP_004327418.1
31 / unnamed protein product [Salmonella phage SFP10] / 97/201(48%) / 8e-56 / YP_004895211.1
32 / Type II secretory pathway, component PulJ [Idiomarina sp. T82-3] / 13/29(45%) / 0.58 / KXS34521.1
33 / hypothetical protein [Klebsiella phage 0507-KN2-1] / 419/473(89%) / 0.0 / YP_008531994.1
34 / hypothetical protein [Dickeya phage Limestone] / 48/83(58%) / 2e-29 / YP_007237351.1
35 / loader of T4-like helicase [Klebsiella phage 0507-KN2-1] / 197/220(90%) / 5e-148 / YP_008531995.1
36 / putative tail length tape measure protein [Klebsiella phage 0507-KN2-1] / 607/661(92%) / 0.0 / YP_008531996.1
37 / hypothetical protein [Klebsiella phage 0507-KN2-1] / 448/462(97%) / 0.0 / YP_008531997.1
38 / baseplate wedge subunit [Klebsiella phage 0507-KN2-1] / 175/185(95%) / 8e-127 / YP_008531998.1
39 / T4-like baseplate tail tube cap [Klebsiella phage 0507-KN2-1] / 321/322(99%) / 0.0 / YP_008531999.1
40 / head completion protein [Klebsiella phage 0507-KN2-1] / 194/205(95%) / 5e-145 / YP_008532000.1
41 / hypothetical protein, partial [Trabulsiella guamensis] / 41/61(67%) / 3e-21 / WP_038163917.1
42 / hypothetical membrane protein [Klebsiella phage 0507-KN2-1] / 119/129(92%) / 8e-83 / YP_008532001.1
43 / Cd allosteric enzyme [Klebsiella phage 0507-KN2-1] / 130/159(82%) / 2e-89 / YP_008532002.1
44 / hypothetical protein [Klebsiella phage 0507-KN2-1] / 99/114(87%) / 5e-70 / YP_008532003.1
45 / hypothetical protein [Klebsiella phage 0507-KN2-1] / 116/131(89%) / 1e-81 / YP_008532004.1
ORF / Top BLAST hita / % identityb (aa) / E valuec / Accession No.
46 / putative serine/threonine protein phosphatase [0507-KN2-1] / 183/190(96%) / 1e-135 / YP_008532007.1
47 / hypothetical protein [Klebsiella phage 0507-KN2-1] / 214/222(96%) / 7e-162 / YP_008532008.1
48 / hypothetical protein MAM_182 [Serratia phage phiMAM1] / 47/72(65%) / 4e-27 / YP_007349161.1
49 / DexA exonuclease [Klebsiella phage 0507-KN2-1] / 195/209(93%) / 4e-145 / YP_008532009.1
50 / putative uncharacterised protein [Salmonella phage ViI] / 63/107(59%) / 4e-28 / YP_004327390.1
51 / conserved hypothetical phage protein [Klebsiella phage 0507-KN2-1] / 195/201(97%) / 6e-143 / YP_008532010.1
52 / hypothetical protein [Salmonella phage vB_SalM_PM10] / 25/73(34%) / 3e-10 / YP_009293421.1
53 / unnamed protein product [Salmonella phage SFP10] / 59/75(79%) / 5e-32 / YP_004895187.1
54 / conserved hypothetical protein [Klebsiella phage 0507-KN2-1] / 121/134(90%) / 7e-88 / YP_008532011.1
55 / hypothetical protein [Salmonella phage GG32] / 43/47(91%) / 1e-24 / ANN85906.1
56 / hypothetical protein G379_gp189 [Dickeya phage Limestone] / 63/96(66%) / 5e-34 / YP_007237338.1
57 / DNA topoisomerase II medium subunit [Klebsiella phage 0507-KN2-1] / 401/431(93%) / 0.0 / YP_008532012.1
58 / topoisomerase II large subunit [Klebsiella phage 0507-KN2-1] / 619/636(97%) / 0.0 / YP_008532013.1
59 / hypothetical protein [Klebsiella phage 0507-KN2-1] / 176/192(92%) / 4e-133 / YP_008532014.1
60 / hypothetical protein [Klebsiella phage 0507-KN2-1] / 156/161(97%) / 7e-115 / YP_008532015.1
61 / putative uncharacterised protein [Salmonella phage ViI] / 28/63(44%) / 4e-11 / YP_004327380.1
62 / unnamed protein product [Salmonella phage SFP10] / 64/73(88%) / 6e-40 / YP_004895177.1
63 / phage tail fiber protein [Escherichia phage ECML-4] / 187/273(68%) / 1e-131 / YP_009101472.1
64 / hypothetical protein [Klebsiella phage 0507-KN2-1] / 59/59(100%) / 2e-36 / YP_008532018.1
65 / hypothetical protein [Klebsiella phage 0507-KN2-1] / 115/136(85%) / 5e-78 / YP_008532019.1
66 / hypothetical protein G379_gp201 [Dickeya phage Limestone] / 66/98(67%) / 4e-43 / YP_007237325.1
67 / RIIB Protector from prophage-induced early lysis [0507-KN2-1] / 490/528(93%) / 0.0 / YP_008532020.1
68 / RIIA protector from prophage-induced early lysis [0507-KN2-1] / 738/894(83%) / 0.0 / YP_008532021.1
ORF / Top BLAST hita / % identityb (aa) / E valuec / Accession No.
69 / hypothetical protein [Klebsiella phage 0507-KN2-1] / 105/112(94%) / 4e-71 / YP_008532022.1
70 / hypothetical protein [Salmonella phage SKML-39] / 35/65(54%) / 1e-12 / YP_007236268.1
71 / hypothetical protein DET7_166 [Salmonella phage Det7] / 102/147(69%) / 1e-66 / YP_009140343.1
72 / hypothetical protein [Klebsiella phage 0507-KN2-1] / 110/128(86%) / 7e-74 / YP_008532024.1
73 / unnamed protein product [Salmonella phage SFP10] / 100/133(75%) / 2e-66 / YP_004895368.1
74 / hypothetical protein [Klebsiella phage 0507-KN2-1] / 178/187(95%) / 1e-129 / YP_008532027.1
75 / hypothetical protein [Klebsiella phage 0507-KN2-1] / 352/364(97%) / 0.0 / YP_008532028.1
76 / hypothetical protein [Shigella phage Ag3] / 84/129(65%) / 1e-55 / YP_003358694.1
77 / hypothetical protein [Klebsiella phage 0507-KN2-1] / 392/405(97%) / 0.0 / YP_008532029.1
78 / hypothetical protein [Klebsiella phage 0507-KN2-1] / 100/115(87%) / 1e-68 / YP_008532030.1
79 / hypothetical protein [Klebsiella phage 0507-KN2-1] / 270/294(92%) / 0.0 / YP_008532031.1
80 / hypothetical protein [Shigella phage Ag3] / 46/65(71%) / 2e-27 / YP_003358685.1
81 / putative 5'(3') deoxyribonucleotidase [Klebsiella phage 0507-KN2-1] / 222/263(84%) / 5e-168 / YP_008532032.1
82 / hypothetical protein [Klebsiella phage 0507-KN2-1] / 100/110(91%) / 8e-70 / YP_008532033.1
83 / DNA polymerase [Klebsiella phage 0507-KN2-1] / 977/998(98%) / 0.0 / YP_008532034.1
84 / hypothetical protein [Klebsiella phage 0507-KN2-1] / 175/183(96%) / 1e-125 / YP_008532035.1
85 / hypothetical protein [Klebsiella phage 0507-KN2-1] / 178/185(96%) / 4e-131 / YP_008532036.1
86 / hypothetical protein SP38_33 [Salmonella phage 38] / 147/180(82%) / 8e-106 / YP_009220777.1
87 / hypothetical protein [Dickeya phage Limestone] / 48/114(42%) / 4e-23 / YP_007237497.1
88 / hypothetical protein [Klebsiella phage 0507-KN2-1] / 143/150(95%) / 3e-90 / YP_008532037.1
89 / hypothetical protein [Salmonella phage GG32] / 137/170(81%) / 1e-96 / ANN85863.1
90 / hypothetical protein [Klebsiella phage 0507-KN2-1] / 203/206(99%) / 1e-149 / YP_008532039.1
91 / hypothetical protein [Shigella phage Ag3] / 147/169(87%) / 2e-106 / YP_003358674.1
ORF / Top BLAST hita / % identityb (aa) / E valuec / Accession No.
92 / hypothetical protein [Klebsiella phage 0507-KN2-1] / 203/210(97%) / 3e-149 / YP_008532040.1
93 / tRNA-Tyr-GTA
94 / tRNA-Asn-GTT
95 / tRNA-Trp-CCA
96 / hypothetical protein [Escherichia phage PhaxI] / 55/65(85%) / 1e-31 / YP_007002816.1
97 / tRNA-Met-CAT
98 / transcriptional regulator [Anaerococcus lactolyticus] / 20/74(27%) / 3.4 / WP_004828532.1
99 / hypothetical protein [Klebsiella phage 0507-KN2-1] / 188/189(99%) / 7e-139 / YP_008532042.1
100 / baseplate wedge subunit [Klebsiella phage 0507-KN2-1] / 549/593(93%) / 0.0 / YP_008532043.1
101 / putative baseplate wedge subunit [Klebsiella phage 0507-KN2-1] / 265/283(94%) / 0.0 / YP_008532044.1
102 / hypothetical protein [Klebsiella phage 0507-KN2-1] / 325/441(74%) / 0.0 / YP_008532045.1
103 / putative tailspike protein [Klebsiella phage 0507-KN2-1] / 338/437(77%) / 0.0 / YP_008532046.1
104 / hypothetical protein [[Enterobacter] aerogenes] / 38/77(49%) / 8e-22 / WP_032705968.1
105 / hypothetical protein RU59_00038 [Enterobacter phage phiEap-1] / 249/508(49%) / 3e-154 / YP_009196380.1
106 / No hit
107 / hypothetical protein [[Enterobacter] aerogenes] / 289/518(56%) / 0.0 / WP_032708633.1
108 / No hit
109 / MULTISPECIES: hypothetical protein [Enterobacteriaceae] / 272/598(45%) / 3e-175 / WP_048982838.1
110 / vrlC protein [Klebsiella phage 0507-KN2-1] / 1543/1612(96%) / 0.0 / YP_008532051.1
111 / unnamed protein product [Salmonella phage SFP10] / 34/48(71%) / 5e-15 / YP_004895329.1
112 / hypothetical protein [Klebsiella phage 0507-KN2-1] / 94/111(85%) / 8e-61 / YP_008532052.1
113 / neck protein [Klebsiella phage 0507-KN2-1] / 244/250(98%) / 0.0 / YP_008532053.1
114 / putative uncharacterised protein [Salmonella phage ViI] / 54/70(77%) / 2e-31 / YP_004327536.1
ORF / Top BLAST hita / % identityb (aa) / E valuec / Accession No.
115 / neck protein [Klebsiella phage 0507-KN2-1] / 203/213(95%) / 7e-150 / YP_008532054.1
116 / proximal tail sheath stabilization [Klebsiella phage 0507-KN2-1] / 226/232(97%) / 2e-170 / YP_008532055.1
117 / terminase DNA packaging enzyme small subunit [0507-KN2-1] / 219/228(96%) / 2e-156 / YP_008532056.1
118 / terminase subunit for DNA packaging, nuclease and ATPase [Klebsiella phage 0507-KN2-1] / 725/736(99%) / 0.0 / YP_008532057.1
119 / tail sheath protein [Klebsiella phage 0507-KN2-1] / 602/631(95%) / 0.0 / YP_008532058.1
120 / GIY-YIG endonuclease [Klebsiella phage 0507-KN2-1] / 134/150(89%) / 8e-100 / YP_008532059.1
121 / Gp19 tail tube protein [Salmonella phage ViI] / 168/177(95%) / 1e-122 / YP_004327529.1
122 / portal vertex protein of the head [Klebsiella phage 0507-KN2-1] / 533/559(95%) / 0.0 / YP_008532061.1
123 / hypothetical protein DET7_9 [Salmonella phage Det7] / 38/52(73%) / 2e-18 / YP_009140186.1
124 / putative prohead core protein [Klebsiella phage 0507-KN2-1] / 96/102(94%) / 2e-61 / YP_008532062.1
125 / putative prohead protease [Klebsiella phage 0507-KN2-1] / 215/221(97%) / 9e-160 / YP_008532063.1
126 / prohead core scaffold protein [Klebsiella phage 0507-KN2-1] / 225/286(79%) / 7e-144 / YP_008532064.1
127 / phage major head protein/major capsid protein [0507-KN2-1] / 425/443(96%) / 0.0 / YP_008532065.1
128 / putative uncharacterized protein [Salmonella phage PhiSH19] / 33/101(33%) / 0.002 / YP_007008100.1
129 / orf183 gene product [Escherichia phage Cba120] / 45/56(80%) / 1e-23 / YP_004957844.1
130 / hypothetical protein [Klebsiella phage 0507-KN2-1] / 39/76(51%) / 1e-17 / YP_008532066.1
131 / hypothetical protein [Klebsiella phage 0507-KN2-1] / 97/143(68%) / 8e-66 / YP_008532067.1
132 / hypothetical protein [Klebsiella phage 0507-KN2-1] / 114/122(93%) / 9e-82 / YP_008532068.1
133 / orf178 gene product [Escherichia phage Cba120] / 73/78(94%) / 5e-48 / YP_004957840.1
134 / hypothetical protein [Salmonella phage GG32] / 64/96(67%) / 6e-39 / ANN86027.1
135 / hypothetical protein [Klebsiella phage 0507-KN2-1] / 124/147(84%) / 4e-89 / YP_008532069.1
136 / hypothetical protein [Dickeya phage Limestone] / 33/55(60%) / 3e-17 / YP_007237452.1
ORF / Top BLAST hita / % identityb (aa) / E valuec / Accession No.
137 / hypothetical protein [Klebsiella phage 0507-KN2-1] / 223/242(92%) / 4e-162 / YP_008532070.1
138 / hypothetical protein [Klebsiella phage 0507-KN2-1] / 183/205(89%) / 6e-135 / YP_008532071.1
139 / Gp3-tail completion [Klebsiella phage 0507-KN2-1] / 157/166(95%) / 4e-112 / YP_008532072.1
140 / putative DNA repair/recombination protein UvsY [0507-KN2-1] / 139/153(91%) / 7e-98 / YP_008532073.1
141 / putative exonuclease [Klebsiella phage 0507-KN2-1] / 223/248(90%) / 4e-169 / YP_008532074.1
142 / putative type III restriction enzyme [Klebsiella phage 0507-KN2-1] / 471/505(93%) / 0.0 / YP_008532075.1
143 / hypothetical protein [Klebsiella phage 0507-KN2-1] / 75/92(82%) / 3e-51 / YP_008532076.1
144 / sliding clamp holder [Klebsiella phage 0507-KN2-1] / 215/222(97%) / 9e-160 / YP_008532077.1
145 / sliding clamp holder [Klebsiella phage 0507-KN2-1] / 318/329(97%) / 0.0 / YP_008532078.1
146 / clamp holder for DNA polymerase [Klebsiella phage 0507-KN2-1] / 134/140(96%) / 1e-94 / YP_008532079.1
147 / RegA translational repressor protein [Klebsiella phage 0507-KN2-1] / 154/154(100%) / 2e-111 / YP_008532080.1
148 / conserved hypothetical protein [Klebsiella phage 0507-KN2-1] / 222/290(77%) / 6e-163 / YP_008532081.1
149 / conserved hypothetical protein [Klebsiella phage 0507-KN2-1] / 373/406(92%) / 0.0 / YP_008532082.1
150 / hypothetical protein [Klebsiella phage 0507-KN2-1] / 563/678(83%) / 0.0 / YP_008532083.1
151 / hypothetical protein [Klebsiella phage 0507-KN2-1] / 113/124(91%) / 2e-73 / YP_008532084.1
152 / hypothetical protein [Klebsiella phage 0507-KN2-1] / 42/44(95%) / 6e-23 / YP_008532087.1
153 / hypothetical protein [Klebsiella phage 0507-KN2-1] / 152/251(61%) / 9e-108 / YP_008532088.1
154 / hypothetical protein [Klebsiella phage 0507-KN2-1] / 86/118(73%) / 2e-56 / YP_008532089.1
155 / hypothetical protein [Klebsiella phage 0507-KN2-1] / 642/732(88%) / 0.0 / YP_008532090.1
156 / putative acyl carrier protein [Klebsiella phage 0507-KN2-1] / 100/107(93%) / 3e-67 / YP_008532091.1
157 / hypothetical protein [Escherichia phage ECML-4] / 40/77(52%) / 3e-21 / YP_009101566.1
158 / conserved uncharacterised protein [Salmonella phage ViI] / 67/79(85%) / 2e-39 / YP_004327491.1
159 / hypothetical protein [Klebsiella phage 0507-KN2-1] / 112/122(92%) / 2e-79 / YP_008532092.1
ORF / Top BLAST hita / % identityb (aa) / E valuec / Accession No.
160 / hypothetical protein [Klebsiella phage 0507-KN2-1] / 19/44(43%) / 0.078 / YP_008532093.1
161 / hypothetical protein N408_08385 [Helicobacter pylori FD703] / 14/46(30%) / 0.99 / EQL66144.1
162 / PREDICTED: sodium/hydrogen exchanger 9B1 [Erinaceus europaeus] / 15/41(37%) / 0.83 / XP_007535971.1
163 / phage associated protein [Klebsiella phage 0507-KN2-1] / 124/130(95%) / 8e-88 / YP_008532094.1