March 2015 PUBMED ABSTRACTS
Huntington's Disease: Looking Beyond the Movement Disorder.
Morreale MK.
Adv Psychosom Med. 2015;34:135-42. doi: 10.1159/000369111. Epub 2015 Mar 30.
PMID: 25832519
T1? imaging in premanifest Huntington disease reveals changes associated with disease progression.
Wassef SN, Wemmie J, Johnson CP, Johnson H, Paulsen JS, Long JD, Magnotta VA.
Mov Disord. 2015 Mar 29. doi: 10.1002/mds.26203. [Epub ahead of print]
PMID: 25820773
Magnetization transfer MRI in dementia disorders, Huntington's disease and parkinsonism.
Tambasco N, Nigro P, Romoli M, Simoni S, Parnetti L, Calabresi P.
J Neurol Sci. 2015 Mar 28. pii: S0022-510X(15)00156-2. doi: 10.1016/j.jns.2015.03.025. [Epub ahead of print] Review.
PMID: 25891828
Cardiac Fas-Dependent and Mitochondria-Dependent Apoptotic Pathways in a Transgenic Mouse Model of Huntington's Disease.
Wu BT, Chiang MC, Tasi CY, Kuo CH, Shyu WC, Kao CL, Huang CY, Lee SD.
Cardiovasc Toxicol. 2015 Mar 24. [Epub ahead of print]
PMID: 25800750
Anxiety in Huntington's Disease.
Dale M, van Duijn E. - Netherlands
J Neuropsychiatry Clin Neurosci. 2015 Mar 24:appineuropsych14100265. [Epub ahead of print]
PMID: 25803201
Scalable production in human cells and biochemical characterization of full-length normal and mutant huntingtin.
Huang B, Lucas T, Kueppers C, Dong X, Krause M, Bepperling A, Buchner J, Voshol H, Weiss A, Gerrits B, Kochanek S.
PLoS One. 2015 Mar 23;10(3):e0121055. doi: 10.1371/journal.pone.0121055. eCollection 2015.
PMID: 25799558
Free PMC Article
Assessing Impairment of Executive Function and Psychomotor Speed in Premanifest and Manifest Huntington's Disease Gene-expansion Carriers.
Unmack Larsen I, Vinther-Jensen T, Gade A, Nielsen JE, Vogel A.
J Int Neuropsychol Soc. 2015 Mar 21(3):193-202. doi: 10.1017/S1355617715000090. Epub 2015 Apr 8.
PMID: 25850430
Progress in Huntington's disease: the search for markers of disease onset and progression.
Mason S, Barker RA.
J Neurol. 2015 Mar 21. [Epub ahead of print]
PMID: 25794860
Central nervous system-specific alterations in the tryptophan metabolism in the 3-nitropropionic acid model of Huntington's disease.
Veres G, Molnár M, Zádori D, Szentirmai M, Szalárdy L, Török R, Fazekas E, Ilisz I, Vécsei L, Klivényi P.
Pharmacol Biochem Behav. 2015 Mar 13;132:115-124. doi: 10.1016/j.pbb.2015.03.002. [Epub ahead of print]
PMID: 25773340
Neuronal identity genes regulated by super-enhancers are preferentially down-regulated in the striatum of Huntington's disease mice.
Achour M, Le Gras S, Keime C, Parmentier F, Lejeune FX, Boutillier AL, Néri C, Davidson I, Merienne K.
Hum Mol Genet. 2015 Mar 17. pii: ddv099. [Epub ahead of print]
PMID: 25784504
Correlation between relaxometry and diffusion tensor imaging in the globus pallidus of Huntington's disease patients.
Syka M, Keller J, Klempír J, Rulseh AM, Roth J, Jech R, Vorisek I, Vymazal J.
PLoS One. 2015 Mar 17;10(3):e0118907. doi: 10.1371/journal.pone.0118907. eCollection 2015.
PMID: 25781024
Free PMC Article
Age-dependent alterations in the cortical entrainment of subthalamic nucleus neurons in the YAC128 mouse model of Huntington's disease.
Callahan JW, Abercrombie ED.
Neurobiol Dis. 2015 Mar 12;78:88-99. doi: 10.1016/j.nbd.2015.03.006. [Epub ahead of print]
PMID: 25772440
Noninvasive prenatal diagnosis of Huntington disease: detection of the paternally inherited expanded CAG repeat in maternal plasma.
van den Oever JM, Bijlsma EK, Feenstra I, Muntjewerff N, Mathijssen IB, Bakker E, van Belzen MJ, Boon EM. The Netherlands
Prenat Diagn. 2015 Mar 12. doi: 10.1002/pd.4593. [Epub ahead of print]
PMID: 25767004
In this validation study, we demonstrated that all fetuses at risk for HD could be identified noninvasively in maternal plasma. Additionally, we have confirmed results from previously described case reports that NIPD for HD can be performed using a direct approach by PCR. For future diagnostics, parental CAG profiles can be used to predict the success rate for NIPD prior to testing.
Enhanced neuronal glucose transporter expression reveals metabolic choice in a HD Drosophila model.
Besson MT, Alegría K, Garrido-Gerter P, Barros LF, Liévens JC.
PLoS One. 2015 Mar 11;10(3):e0118765. doi: 10.1371/journal.pone.0118765. eCollection 2015.
PMID: 25761110
Free PMC Article
Effects on murine behavior and lifespan of selectively decreasing expression of mutant huntingtin allele by supt4h knockdown.
Cheng HM, Chern Y, Chen IH, Liu CR, Li SH, Chun SJ, Rigo F, Bennett CF, Deng N, Feng Y, Lin CS, Yan YT, Cohen SN, Cheng TH.
PLoS Genet. 2015 Mar 11;11(3):e1005043. doi: 10.1371/journal.pgen.1005043. eCollection 2015 Mar.
PMID: 25760041
Free PMC Article
Enhanced neuronal glucose transporter expression reveals metabolic choice in a HD Drosophila model.
Besson MT, Alegría K, Garrido-Gerter P, Barros LF, Liévens JC.
PLoS One. 2015 Mar 11;10(3):e0118765. doi: 10.1371/journal.pone.0118765. eCollection 2015.
PMID: 25761110
Free PMC Article
Probing the Huntingtin 1-17 membrane anchor on a phospholipid bilayer by using all-atom simulations.
Côté S, Binette V, Salnikov ES, Bechinger B, Mousseau N.
Biophys J. 2015 Mar 10;108(5):1187-98. doi: 10.1016/j.bpj.2015.02.001.
PMID: 25762330
HDAC4-myogenin axis as an important marker of HD-related skeletal muscle atrophy.
Mielcarek M, Toczek M, Smeets CJ, Franklin SA, Bondulich MK, Jolinon N, Muller T, Ahmed M, Dick JR, Piotrowska I, Greensmith L, Smolenski RT, Bates GP.
PLoS Genet. 2015 Mar 6;11(3):e1005021. doi: 10.1371/journal.pgen.1005021. eCollection 2015 Mar.
PMID: 25748626
Free PMC Article
Cortical efferents lacking mutant huntingtin improve striatal neuronal activity and behavior in a conditional mouse model of Huntington's disease.
Estrada-Sánchez AM, Burroughs CL, Cavaliere S, Barton SJ, Chen S, Yang XW, Rebec GV.
J Neurosci. 2015 Mar 11;35(10):4440-51. doi: 10.1523/JNEUROSCI.2812-14.2015.
PMID: 25762686
Probing the Huntingtin 1-17 membrane anchor on a phospholipid bilayer by using all-atom simulations.
Côté S, Binette V, Salnikov ES, Bechinger B, Mousseau N.
Biophys J. 2015 Mar 10;108(5):1187-98. doi: 10.1016/j.bpj.2015.02.001.
PMID: 25762330
Inter-limb coupling during diadochokinesis in Parkinson's and Huntington's disease.
Daneault JF, Carignan B, Sadikot AF, Duval C.
Neurosci Res. 2015 Mar 6. pii: S0168-0102(15)00071-1. doi: 10.1016/j.neures.2015.02.009. [Epub ahead of print]
PMID: 25747139
The emerging role of the first 17 amino acids of huntingtin in Huntington's disease.
Arndt JR, Chaibva M, Legleiter J.
Biomol Concepts. 2015 Mar;6(1):33-46. doi: 10.1515/bmc-2015-0001.
PMID: 25741791
A striatal-enriched intronic GPCR modulates huntingtin levels and toxicity.
Yao Y, Cui X, Al-Ramahi I, Sun X, Li B, Hou J, Difiglia M, Palacino J, Wu ZY, Ma L, Botas J, Lu B.
Elife. 2015 Mar 4;4. doi: 10.7554/eLife.05449.
PMID: 25738228
Free PMC Article
Performance of the 12-item WHODAS 2.0 in prodromal Huntington disease.
Kim JI, Long JD, Mills JA, Downing N, Williams JK, Paulsen JS; the PREDICT-HD Investigators and Coordinators of the Huntington Study Group.
Eur J Hum Genet. 2015 Mar 4. doi: 10.1038/ejhg.2015.11. [Epub ahead of print]
PMID: 25735480
Domains and correlates of clinical balance impairment associated with Huntington's disease.
Jacobs JV, Boyd JT, Hogarth P, Horak FB.
Gait Posture. 2015 Mar;4 1(3):867-70. doi: 10.1016/j.gaitpost.2015.02.018. Epub 2015 Mar 9.
PMID: 25797790
HD iPSC-derived neural progenitors accumulate in culture and are susceptible to BDNF withdrawal due to glutamate toxicity.
Mattis VB, Tom C, Akimov S, Saeedian J, Østergaard ME, Southwell AL, Doty CN, Ornelas L, Sahabian A, Lenaeus L, Mandefro B, Sareen D, Arjomand J, Hayden MR, Ross CA, Svendsen CN.
Hum Mol Genet. 2015 Mar 3. pii: ddv080. [Epub ahead of print]
PMID: 25740845
Modulation of the glutamatergic transmission by Dopamine: a focus on Parkinson, Huntington and Addiction diseases.
Gardoni F, Bellone C.
Front Cell Neurosci. 2015 Mar 2;9:25. doi: 10.3389/fncel.2015.00025. eCollection 2015. Review.
PMID: 25784855
Free PMC Article
miR-10b-5p expression in Huntington's disease brain relates to age of onset and the extent of striatal involvement.
Hoss AG, Labadorf A, Latourelle JC, Kartha VK, Hadzi TC, Gusella JF, MacDonald ME, Chen JF, Akbarian S, Weng Z, Vonsattel JP, Myers RH.
BMC Med Genomics. 2015 Mar 1;8(1):10. doi: 10.1186/s12920-015-0083-3.
PMID: 25889241
Free PMC Article
Selective loss of oxytocin and vasopressin in the hypothalamus in early Huntington disease: a case study.
Gabery S, Halliday G, Kirik D, Englund E, Petersén Å. Sweden
Neuropathol Appl Neurobiol. 2015 Mar 13. doi: 10.1111/nan.12236. [Epub ahead of print] No abstract available.
PMID: 25765897
February 2015
[Gene silencing approaches for the treatment of Huntington's disease].
Merienne N, Déglon N.
Med Sci (Paris). 2015 Feb;31(2):159-67. doi: 10.1051/medsci/20153102012. Epub 2015 Mar 4. Review. French.
PMID: 25744262
Treadmill exercise improves short-term memory by enhancing hippocampal cell proliferation in quinolinic acid-induced Huntington's disease rats.
Kim YM, Ji ES, Kim SH, Kim TW, Ko IG, Jin JJ, Kim CJ, Kim TW, Kim DH.
J Exerc Rehabil. 2015 Feb 28;11(1):5-11. doi: 10.12965/jer.150182. eCollection 2015 Feb.
PMID: 25830138
Free PMC Article
Reduction in subventricular zone-derived olfactory bulb neurogenesis in a rat model of Huntington's disease is accompanied by striatal invasion of neuroblasts.
Kandasamy M, Rosskopf M, Wagner K, Klein B, Couillard-Despres S, Reitsamer HA, Stephan M, Nguyen HP, Riess O, Bogdahn U, Winkler J, von Hörsten S, Aigner L.
PLoS One. 2015 Feb 26;10(2):e0116069. doi: 10.1371/journal.pone.0116069. eCollection 2015.
PMID: 25719447
Free PMC Article
Functional connectivity modeling of consistent cortico-striatal degeneration in Huntington's disease.
Dogan I, Eickhoff CR, Fox PT, Laird AR, Schulz JB, Eickhoff SB, Reetz K.
Neuroimage Clin. 2015 Feb 27;7:640-52. doi: 10.1016/j.nicl.2015.02.018. eCollection 2015.
PMID: 25844318
Free PMC Article
Prevalence of Huntington's disease gene CAG trinucleotide repeat alleles in patients with bipolar disorder.
Ramos EM, Gillis T, Mysore JS, Lee JM, Alonso I, Gusella JF, Smoller JW, Sklar P, MacDonald ME, Perlis RH.
Bipolar Disord. 2015 Feb 26. doi: 10.1111/bdi.12289. [Epub ahead of print]
PMID: 25726852
Undated
[Psychiatric problems in a motor disorder: psychosis in Huntington's disease].
van der Weijde E, Schadé A.
Tijdschr Psychiatr. 2015;57(3):215-9. Dutch.
PMID: 25856745
Free Article