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Air pollution and stroke: supplementary materials

Table S1: Adjusted ORsa for ED visits for acute ischemic stroke among the elderly associated with per IQR increasein AQHI during the warm seasonb

Lag periods / Aged >= 65 years old / Aged >=75 years old
1-8 hrs / 1.06 (0.99-1.13) / 1.14 (1.03-1.27)
9-16 hrs / 1.08 (1.01-1.15) / 1.17 (1.05-1.30)
17-24 hrs / 1.06 (1.00-1.14) / 1.12 (1.01-1.24)
1-24 hrs / 1.10 (1.02-1.19) / 1.23 (1.08-1.40)
25-48 hrs / 1.09 (1.00-1.18) / 1.15 (1.01-1.31)
1-48 hrs / 1.13 (1.03-1.24) / 1.26 (1.09-1.47)
49-72 hrs / 1.03 (0.95-1.12) / 1.11 (0.97-1.26)
1-72 hrs / 1.12 (1.01-1.25) / 1.30 (1.10-1.54)

aORs were adjusted for temperature and relative humidity in the same time periods as AQHI.

b Warm season is April – September

Table S2: Adjusted ORsa for ED visits for acute ischemic stroke among the elderlybassociated with per IQR increasein AQHI/ or NO2during the cold seasonc

Lag periods / AQHI_IQR / NO2_ per IQR
1-8 hrs / 1.07 (0.96-1.20) / 1.07 (0.94-1.21)
9-16 hrs / 1.07 (0.96-1.20) / 1.05 (0.93-1.18)
17-24 hrs / 1.10 (0.99-1.22) / 1.08 (0.96-1.22)
1-24 hrs / 1.11 (0.98-1.26) / 1.09 (0.94-1.25)
25-48 hrs / 1.07 (0.95-1.21) / 1.13 (0.98-1.30)
1-48 hrs / 1.12 (0.97-1.28) / 1.15 (0.97-1.35)
49-72 hrs / 0.97 (0.86-1.10) / 0.98 (0.85-1.13)
1-72 hrs / 1.07 (0.92-1.25) / 1.10 (0.92-1.32)

aORs were adjusted for temperature and relative humidity in the same time periods as AQHI or NO2.

b The patients aged 75 years and older

cCold season is October – March

Table S3: Adjusted ORsa for ED visits for acute ischemic stroke among the elderlybassociated with per IQR increasein AQHI during the warm seasonc

by sex

Lag periods / Female(n=694) / Male(n=517)
1-8 hrs / 1.21 (1.05-1.39) / 1.08 (0.93-1.26)
9-16 hrs / 1.14 (0.99-1.31) / 1.21 (1.02-1.43)
17-24 hrs / 1.02 (0.89-1.17) / 1.28 (1.08-1.50)
1-24 hrs / 1.17 (0.99-1.38) / 1.31 (1.08-1.60)
25-48 hrs / 1.11 (0.94-1.31) / 1.21 (0.99-1.47)
1-48 hrs / 1.19 (0.98-1.44) / 1.38 (1.10-1.74)
49-72 hrs / 1.12 (0.95-1.33) / 1.08 (0.88-1.33)
1-72 hrs / 1.23 (0.99-1.53) / 1.40 (1.08-1.82)

aORs were adjusted for temperature and relative humidity in the same time periods as AQHI or NO2.

b The patients aged 75 years and older

cWarm season is April - September

Table S4: Comparison AIC values between AQHI model and single pollutant models

Lag perieds / AIC
Without covariates / AIC
With covariates
AQHI
1-8 hrs / 3578.00 / 3577.00
9-16 hrs / 3573.89 / 3571.72
1-24 hrs / 3578.45 / 3574.25
25-28 hrs / 3576.74 / 3577.60
1-72 hrs / 3593.01 / 3588.42
NO2
1-8 hrs / 3599.45 / 3590.29
9-16 hrs / 3599.45 / 3594.25
1-24 hrs / 3599.45 / 3587.57
25-28 hrs / 3599.45 / 3593.03
1-72 hrs / 3599.45 / 3585.89
PM2.5
1-8 hrs / 3578.00 / 3580.21
9-16 hrs / 3573.89 / 3576.37
1-24 hrs / 3578.45 / 3579.77
25-28 hrs / 3576.74 / 3580.29
1-72 hrs / 3593.01 / 3594.39
O3
1-8 hrs / 3599.45 / 3601.02
9-16 hrs / 3599.45 / 3602.98
1-24 hrs / 3599.45 / 3601.67
25-28 hrs / 3599.45 / 3601.02
1-72 hrs / 3599.45 / 3600.79