1
“International Cardiovascular Genomic medicine conference”
“FROM GENOME DIAGNOSIS TO THERAPY OF INHERITED CARDIOVASCULAR DISEASES”
30-31 October 2017
Radisson Blu Convention Center, Cardiff, Wales, UK
Convenor: Prof. Dhavendra Kumar
Organised by- The Genomic Medicine Foundation (UK)
Scientific Program Committee
Prof. Dhavendra Kumar, Cardiff, UK (Chair)
Prof. Perry Elliott, London, UK
Dr. Arthur Wilde, Amsterdam, NL
Dr. Lorenzo Monserratt, La Coruna, Spain
Dr. Elijah Behr, London, UK
Dr. Julie de Backer, Ghent, Belgium
PROVISIONAL PROGRAMME
DAY 1: 30 October 2017
0830 Registration/ Coffee
0915 Welcome/ Introduction Professor Dhavendra Kumar
Session I: CONGENITAL CLINICAL CARDIOLOGY
Chairs: Dr. Juan Kaski, GOSH, London & Dr. graham stuart, bristol, uk
0930 ‘New genomic and molecular insights in cardiovascular development’
Dr. Jean Luc Balligand , UH Brussels, Belgium
0950 ‘Genomic profiling in monogenic malformation syndromes with cardiovascular phenotype’
Dr. Catherine Mercer, Southampton, UK
1010 ‘Genomic heterogeneity of vascular phenotypes of inherited connective tissue disease’
Prof. Julie de Baker, Ghent, Belgium
1030 OPEN
1040 OPEN
1050 Questions & Discussion
1100 COFFEE
1115 Key note lecture I
CHAIR: DR. DIRK WILSON, PAEDIATRIC CARDIOLOGY, UHW, CARDIFF,UK
‘the expanding landscape of the tgf-beta molecular FAMILY”
professor bart loeys, antwerp, belgium
Session II: functional vascular disease
CHAIR: Prof. Alan Fraser, UHW, Cardiff
1200 ‘Genomic insights of essential hypertension and clinical applications’
Professor Patricia Munroe, William Harvey Research Institute, QMUL, London
1220 ‘Molecular heterogeneity in pulmonary arterial hypertension’
Professor Robert Tulloh, Bristol Royal Infirmary, Bristol
1240 Questions & Discussion
1245 LUNCH
1400 SESSION III: CARDIAC CONDUCTION AND RHYTHM DISORDERS
Chairs: Dr. Elijah Behr, St. George’s, London, UK
Dr. Peter O’Callaghan, UHW, Cardiff, UK
1400 ‘Clinical and molecular heterogeneity of the SCN5A related cardiac phenotypes’
Professor Arthur Wilde, Academic Medical Centre, Amsterdam, The Netherlands
1430 ‘Molecular complexities of atrial fibrillation and related disorders’
Professor Pier Lambiase, UCL & St. Bart’s, London
1500 OPEN
1510 OPEN
1520 Questions & Discussion
1530 TEA BREAK
SESSION IV: CARDIOVASCULAR PHARMACOGENOMICS
CHAIR: Dr. CHRISTOPHER MADLER, NEWPORT, WALES, UK
1545 ‘Genomic insights of drug induced arrhythmias’
Dr. Elijah Behr, St. George’s Hospital, Medical School, London, UK
1615 ‘Genetic & Genomic selection for cardiovascular pharmacotherapy’
Dr. Richard Turner, MRC Centre for Pharmacogenomics, Liverpool, UK
1645 OPEN
1655 OPEN
1705 Questions & Discussion
1715 SESSION V: KEY NOTE LECTURE II
CHAIR: PROF. ZAHEER YOUSEF, UHW, CARDIFF, UK
Professor BILL MCKENNA, UCL & QATAR
“Emerging avenues of molecular therapy for Inherited Cardiac Conditions”
1800 CLOSE
1900 DRINKS RECEPTION/ JAZZ QUARTET
2000 GALA DINNER
DAY 2: 31 October 2017
0830 Registration/ Coffee
SESSION VI: CARDIAC AND VOLUNTARY MUSCLE DISORDERS
CHAIRS: PROFESSOR PERRY ELLIOTT, LONDON, UK
DR MARK ROGERS, UHW, CARDIFF, UK
0900 “Broadening spectrum of cardiac sarcomeres family- genotype phenotype correlations”
Professor Perry Elliott, UCL & St Bart’s, London
0930 “Molecular advances in arrhythmogenic cardiomyopathy”
Kalliopi Pilichou, Department of Cardiac, Thoracic and Vascular Sciences, University of Padua, Padua, Italy
1000 ‘New genomic biomarkers and therapy for ARVC’
Professor Robert Hamilton, Hospital Sick Kids, Toronto, Canada
1030 ‘Expanding genomic horizons of dilated cardiomyopathy’
Professor Eloisa Arbustini, University of Pavia, Italy
1100 “Cardiac phenotypes in rare primary myopathies- genotype: phenotype correlations’
Professor Francesco Muntoni, UCL & GOSH, London, UK
1130 GUEST LECTURE BY PROFESSOR SIR NILESH SAMANI,
MEDICAL DIRECTOR BHF & PROFESSOR OF CARDIOVASCULAR MEDICINE, LEICESTER, UK
INTRODUCTION- PROFESSOR DHAVENDRA KUMAR
TOPIC- TBC
1230 LUNCH/ POSTER VIEWING
1400 SESSION VII: DIAGNOSTIC CARDIOVASCULAR GENOMIC MEDICINE
CHAIRS: DR. RACHEL BUTLER, IMG, UHW, CARDIFF, UK
DR. KAREN MCGUIRE, OXFORD MOLECULAR GENETICS, OXFORD, UK
1400 “The impact of NGS testing for inherited cardiovascular disease”
Dr. Lorenzo Monserrat, La Coruna, Spain
1430 “Complexities and challenges of genome diagnostics in clinical practice’
Dr. Antoine Bondue, Erasme Hospital, Brussels, Belgium
1450 OPEN
1500 OPEN
1510 Questions & Discussion
SESSION VIII: FATAL AND NEAR MISS LIFE THREATENING OUTCOMES
CHAIRS: Prof. MARY SHEPARD, ST. GEORGE’S HOSPITAL, LONDON, UK
DR. SARJU MEHTA, ADDENBROOKE’S HOSPITAL, CAMBRIDGE, UK
1515 ‘Genomic perspectives of sudden cardiac death in Sports & Athletics’
Professor Sanjay Sharma, St. George’s, London, UK
1545 ‘Peripartum cardiomyopathy- Genetic and Genomic perspectives’
Dr. James Ware, Imperial College of Medicine & Royal Brompton Hospital, London, UK
1615 ‘Targeting prevention of sudden cardiac death’
Dr. Andrew Grace, Addenbrooke’s Hospital, Cambridge, Engalnd, UK
1645 Questions & Discussion/ Closing summary
1700 CLOSE/ GOODBYE
Faculty
Prof. Dhavendra Kumar, University Hospital of Wales, Cardiff, UK (Chair)
;
Prof. Perry Elliott, UCL/ Bart’s, London, UK
Prof. Sir Nilesh Samani, BHF Medical Director & Leicester University, UK
Dr. Richard Turner, MRC Centre for Pharmacogenomics, Liverpool, UK
Prof. Francesco Muntoni, UCL/ Inst. Child Health/GOSH, London, UK
Prof. Arthur Wilde, Academic Medical Centre, Amsterdam, NL
Dr. Lorenzo Monserrat, Health in Code, La Coruna, Spain
Dr. Elijah Behr, St. George’s Hospital Medical School. London, UK
Prof. Julie de Backer, Medical Genetics Centre, University of Ghent, Belgium
Professor Sanjay Sharma, St. George’s, London, UK
;
Dr. James Ware, Imperial College of Medicine & Royal Brompton Hospital, London, UK
Prof. Bart Loeys, Centre for Medical Genetics, Univ. Antwerp, Belgium
Dr. Antoine Bondue, Erasme Hospital, Brussels, Belgium
(Bondue Antoine )
Professor Robert Hamilton, Hospital Sick Kids, Toronto, Canada
Professor Eloisa Arbustini, University of Pavia, Italy
Dr. Jean Luc Balligand , Université catholique de Louvain, Tour Vésale +5, 52 avenue Mounier, 1200 Bruxelles
Dr. Catherine Mercer, Princess Ann Hospital, Southampton, UK
Prof. Robert Tulloh, Bristol Royal Infirmary, UK
Prof. Patricia Munroe, William Harvey Research Centre, QMUL, UK
Dr. Kalliopi Pilichou/ Prof. Cristina Basso, Department of Cardiac, Thoracic and Vascular Sciences, University of Padua, Padua, Italy
Dr. Andrew Grace, Addenbrooke’s Hospital, Cambridge, Engalnd, UK