I. Gene and cellular therapy.
The main publications on the scientific direction:
1. Khaiboullina SF, Rizvanov AA, Lombardi VC, Morzunov SP, Reis HJ, Palotás A, St Jeor S. Andes-virus-induced cytokine storm is partially suppressed by ribavirin. Antivir Ther. 2013 Jan 8. doi: 10.3851/IMP2524. [Epub ahead of print]
2. I.G. Starostina, V.V. Solovyeva, K.G. Shevchenko, R.V. Deev, A.A. Isaev, A.A. Rizvanov. Formation of the recombinant adenovirus encoding codon-optimized dysferlin gene and analysis of the recombinant protein expression in cell culture in vitro. Cellular Transplantation and Tissue Engineering. 2012. Vol. 7(3): 25-28 (SCOPUS Cited Publication. In Russian)
3. R.F. Gaifullina, M.N. Katina, S.R. Abdulhakov, L.R. Kasimova, A.R. Abdulhakova, A.A. Rizvanov. Liver pathomorphology of Mus musculus C57BL6 on atherogenic diet. Cellular Transplantation and Tissue Engineering. 2012. Vol. 7(3): 37-40 (SCOPUS Cited Publication. In Russian)
4. M.N. Katina, R.F. Gaifullina, Z.G. Hayatova, Ch.Ch. Emene, A.A. Rizvanov. Isolation, culture and differentiation of rat (Rattus norvegicus) and hamster (Mesocricetus auratus) adipose derived multipotent mesenchymal stromal cells. Cellular Transplantation and Tissue Engineering. 2012. Vol. 7(3): 82-87 (SCOPUS Cited Publication. In Russian)
5. N.V. Kudryashova, D.S. Guseva, I.I. Salafutdinov, F.V. Bashirov, A.P. Kiiasov, A.A. Rizvanov, R.R. Islamov. Human umbilical cord blood mononuclear cells transfected with dual cassette plasmids (vegf + neurotrophic factor) for the treatment of amyotrophic lateral sclerosis. Cellular Transplantation and Tissue Engineering. 2012. Vol. 7(3): 92-97 (SCOPUS Cited Publication. In Russian)
6. E.V. Martinova, Y.V. Danilova, V.A. Anohin, S.F. Khaiboullina, A.A. Rizvanov, M.R. Sharipova. Biosafety model of adenovirus infection: effects of bacterial proteases for infection of human cells in vitro. Cellular Transplantation and Tissue Engineering. 2012. Vol. 7(3): 105-107 (SCOPUS Cited Publication. In Russian)
7. О. Mijanovic, А.К. Shafigullina, А.А. Rizvanov, А.P. Kiasov. Isolation and cultivation of myofibroblasts from rats’ liver using explantation method. Cellular Transplantation and Tissue Engineering. 2012. Vol. 7(3): 112-115 (SCOPUS Cited Publication. In Russian)
8. Y.O. Mukhamedshina, G.F. Shaymardanova, A.R. Muhitov, I.I. Salafutdinov, V.N. Zarubina, А.А. Rizvanov, Yu.A. Chelyshev. Survival and differentiation of endogenous Schwann cells migrating into spinal cord under the influence of neurotrophic factors. Cellular Transplantation and Tissue Engineering. 2012. Vol. 7(3): 125-129 (SCOPUS Cited Publication. In Russian)
9. Y.O. Mukhamedshina, V.V. Solovieva, I.I. Salafutdinov, E.E. Cherenkova, V.Y. Fedotova, Z.Z. Safiullov, A.A. Izmailov, G.A. Sharifullina, S.R. Abdulhakov, M.S. Kaligin, F.V. Bashirov, M.A. Muhamediarov, M.M. Shmarov, B.S. Naroditskii, A.P. Kiiasov, A.A. Rizvanov, R.R. Islamov. Analysis of recombinant vegf gene expression by genetically modified umbilical cord blood mononuclear cells in experiment in vivo. Cellular Transplantation and Tissue Engineering. 2012. Vol. 7(3): 130-134 (SCOPUS Cited Publication. In Russian)
10. M.A. Mukhamedyarov, Z.Z. Safiullov, R.P. Utyasheva, A.A. Rizvanov, A.L. Zefirov, R.R. Islamov. The mechanism of β-amyloid peptide influence on the retrograde axon transport. Cellular Transplantation and Tissue Engineering. 2012. Vol. 7(3): 135-137 (SCOPUS Cited Publication. In Russian)
11. J.J. Romanova, I.I. Salafutdinov, N.M. Zamalyutdinova, A.A. Rizvanov. Chromatographic purification of plasmid DNA for clinical applications (gene therapy). Cellular Transplantation and Tissue Engineering. 2012. Vol. 7(3): 142-145 (SCOPUS Cited Publication. In Russian)
12. V.V. Solovyeva, A.A. Isaev, D.D. Genkin, A.A. Rizvanov. Influence of recombinant histone H1.3 on the efficiency of lentiviral transduction of human cells in vitro. Cellular Transplantation and Tissue Engineering. 2012. Vol. 7(3): 151-154 (SCOPUS Cited Publication. In Russian)
13. V.V. Solovyeva, N.L. Blatt, A.K. Shafigullina, A.A. Rizvanov. Endogenous secretion of vascular endothelial growth factor by multipotent mesenchymal stromal cells derived from human third molar dental follicles. Cellular Transplantation and Tissue Engineering. 2012. Vol. 7(3): 155-158 (SCOPUS Cited Publication. In Russian)
14. E.E. Cherenkova, V.Y. Fedotova, M.A. Borisov, R.R. Islamov, A.A. Rizvanov. Generation of recombinant adenoviruses and lentiviruses expressing angiogenic and neuroprotective factors using Gateway cloning technology. Cellular Transplantation and Tissue Engineering. 2012. Vol. 7(3): 164-168 (SCOPUS Cited Publication. In Russian)
15. A.K. Shafigullina, A.A. Gumerova, A.A. Trondin, M.A. Titova, I.M. Gazizov, G.R. Burganova, M.S. Kaligin, D.I. Andreeva, A.A. Rizvanov, A.R. Muhamedov, A.P. Kiassov. Transplanted Hepatic Stellate Cells participate in liver regeneration after partial hepatectomy without risk of hepatic fibrosis. Cellular Transplantation and Tissue Engineering. 2012. Vol. 7(3): 169-172 (SCOPUS Cited Publication. In Russian)
16. R.F. Mastgutov, A.A. Rizvanov, I.I. Salafutdinov, I.G. Hannanova, R.I. Mullin, A.A. Bogov jr., A.R. Gallyamov, A.A. Bogov. Correction of the face soft tissue defect using autologous fat tissue enriched by cells of stromal-vascular fraction. Cellular Transplantation and Tissue Engineering. 2012. Vol. 7(3): 177-179 (SCOPUS Cited Publication. In Russian)
17. M.V. Plotnikov, A.A. Rizvanov, R.F. Masgutov, M.O. Mavlikeev, I.I. Salafutdinov, I.M. Gazizov, Y.D. Romanova, I.I. Shamsutdinova, A.A. Bogov, A.V. Maksimov. The first clinical experience of direct gene therapy using VEGF and bFGF in treatment patients with critical lower limb ischemia. Cellular Transplantation and Tissue Engineering. 2012. Vol. 7(3): 180-185 (SCOPUS Cited Publication. In Russian)
18. E.I. Shagimardanova, M.R. Sharipova, A.A. Rizvanov, I.S. Zaharov, O.A. Gusev. Life without water: cryptobiosis of invertebrates as a model for next generation techmology of biomaterials preservation. Cellular Transplantation and Tissue Engineering. 2012. Vol. 7(3): 185-189 (SCOPUS Cited Publication. In Russian).
19. Doğan A, Yalvaç ME, Sahin F, Kabanov AV, Palotás A, Rizvanov AA. Differentiation of human stem cells is promoted by amphiphilic pluronic block copolymers. Int J Nanomedicine. 2012;7:4849-4860.
20. Martins LC, Rocha NP, Torres KC, Dos Santos RR, França GS, de Moraes EN, Mukhamedyarov MA, Zefirov AL, Rizvanov AA, Kiyasov AP, Vieira LB, Guimarães MM, Yalvaç ME, Teixeira AL, Bicalho MA, Janka Z, Romano-Silva MA, Palotás A, Reis HJ. Disease-specific expression of the serotonin-receptor 5-HT(2C) in natural killer cells in Alzheimer's dementia. J Neuroimmunol. 2012 Oct 15;251(1-2):73-9.
21. A.A. Rizvanov, D.S. Guseva, I.I. Salafutdinov, F.V. Bashirov, A.P. Kijasov, R.R. Islamov. Treatment of the amyotrophic lateral sclerosis using of genetically modified umbilical cord blood mononuclear cells in the preclinical studies. Cellular Transplantation and Tissue Engineering. 2012. Vol. 7(2): 56-63 (SCOPUS Cited Publication. In Russian).
22. N.P. Rocha, A.L. Teixeira, F.M. Coelho, P. Caramelli, H.C. Guimarães, I.G. Barbosa, T.A. da Silva, M.A. Mukhamedyarov, A.L. Zefirov, A.A. Rizvanov, A.P. Kiyasov, L.B. Vieira, Z. Janka, A. Palotás, H.J. Reis. Peripheral blood mono-nuclear cells derived from Alzheimer's disease patients show elevated baseline levels of secreted cytokines but resist stimulation with β-amyloid peptide. Molecular and Cellular Neuroscience. 2012 Jan;49(1):77-84.
23. A.A. Rizvanov, S. Gulluoglu, M.E. Yalvaç, A. Palotás, R.R. Islamov. RNA Interference and Amyotrophic Lateral Sclerosi. Current Drug Metabolism. 2011;12:679-683.
24. M.E. Yalvac, A. Yilmaz, D. Mercan, S. Aydin, A. Dogan, A. Arslan, Z. Demir, I.I. Salafutdinov, A.K. Shafigullina, F. Sahin, A.A. Rizvanov, A. Palotas. Differentiation and Neuro-Protective Properties of Immortalized Human Tooth Germ Stem Cells. Neurochemical Research. 2011 Dec;36(12):2227-35.
25. R.R. Islamov, A.A. Rizvanov, O.V. Tyapkina, B.S. Shenkman, I.B. Kozlovskaya, E.E. Nikolskiy, A.I. Grigoryev. Genomic Study of Gene Expression in the Mouse Lumbar Spinal Cord under the Conditions of Simulated Microgravity. Doklady Biological Sciences. 2011;439:197–200.
26. N.I. Lannik, D.S.Tarasov, K.A. Petrov, E.A. Bukharaeva, E.E. Nikolsky, A.A. Rizvanov. Specification of primary nucleotide sequence and exon-intron structure of Rattus norvegicus acetylcholinesterase gene // Scientific Reports of Kazan University. 2010. Vol.153(1):120-126. (in Russian).
27. E.P. Guven, M.E. Yalvac, F. Sahin, M.M. Yazici, A.A. Rizvanov, G.Bayirli. Effect of Dental Materials Calcium Hydroxide-containing Cement, Mineral Trioxide Aggregate, and Enamel Matrix Derivative on Proliferation and Differentiation of Human Tooth. Journal of Endodontics. 2011 May;37(5):650-656.
28. I.I. Shakhmaeva, E.R. Bulatov, O.V. Bondar, D.V. Saifullina, M. Culha, A.A. Rizvanov, T.I. Abdullin. Binding and purification of plasmid DNA using multi-layered carbon nanotubes. Journal of Biotechnology. 2011 Mar 20;152(3):102-7.
29. K.A. Petrov, L.O. Yagodina, G.R. Valeeva, N.I. Lannik, A.D. Nikitashina, A.A. Rizvanov, V.V. Zobov, E.A. Bukharaeva, V.S. Reznik, F. Vyskočil, E.E. Nikolsky. Different sensitivities of rat skeletal muscles and brain to novel anti-cholinesterase agents, alkylammonium derivatives of 6-methyluracil (ADEMS). British Journal of Pharmacology. 2011 Jun;163(4):732-744.
30. H.J. Reis, L. Wang, T. Verano-Braga, A.M.C. Pimenta, J. Kálmán, G. Bogáts, B. Babik, L.B. Vieira, A.L. Teixeira, M.A. Mukhamedyarov, A.L. Zefirov, A.P. Kiyasov, A.A. Rizvanov, K. Matin, M. Palotás, M.M. Guimarães, C.N. Ferreira, M.E. Yalvaç, Z. Janka and A. Palotás. Evaluation of Post-Surgical Cognitive Function and Protein Fingerprints in the Cerebro-Spinal Fluid Utilizing Surface-Enhanced Laser Desorption/Ionization Time-of-Flight Mass-Spectrometry (SELDI-TOF MS) After Coronary Artery Bypass Grafting: Review of Proteomic Analytic Tools and Introducing a New Syndrome. Current Medicinal Chemistry. 2011;18(7):1019-37.
31. A.A. Rizvanov, D.S. Guseva, I. I. Salafutdinov, N.V. Kudryashova, F.V. Bashirov, A.P. Kiyasov, M.E. Yalvaç, I.M. Gazizov, M.S. Kaligin, M.A. Mukhamedyarov, A. Palotás, R.R. Islamov. Genetically modified human umbilical cord blood cells expressing VEGF and FGF2 differentiate into glial cells after transplantation into amyotrophic lateral sclerosis (ALS) transgenic mice. Experimental Biology and Medicine. 2011 Jan 1;236(1):91-8.
32. A.A. Toymentseva, M.R. Karimova, A.A. Rizvanov, E.I. Shagimordanova, M.R. Sharipova. Bacillus intermedius with knocked-out gene of subtilisin-like protease // Scientific Reports of Kazan University. 2010. Vol.152(4):143-155. (in Russian).
33. A.A. Rizvanov, D.S. Guseva, I.I. Salafutdinov, N.V. Kudryashova, A.K. Shafigullina, F.V. Bashirov, I.M. Gazizov, M.S. Kaligin, M.A. Mukhamedyarov, AP. Kiyasov, R.R. Islamov. Gene-cell therapy of amyotrophic lateral sclerosis with human umbilical cord blood mononuclear cells overexpressing neural adhesion molecule L1cam and vascular endothelial growth factor vegf genes. Cellular transplantology and tissue engineering. 2010. Vol. 5(4): 55-65 (in Russian).
34. F.F. Rizvanova, O.I. Pikuza, R.A. Faizullina, R.F. Gaifullina, А.А. Rizvanov, О.А. Kravtsova. Genetic diagnosis: polymorphism of cytokine genes. Practical medicine. 2010. Vol. 6(45): 41-43 (in Russian).
35. F.F. Rizvanova, R.T. Gabbasov, E.V. Vavilova, O.I. Pikuza, A.A. Rizvanov, O.A. Kravtsova. The influence of polymorphism of genes of interleukin-4 and interleukine-6 susceptibility to respiratory diseases among children and the distribution of allele frequencies in the population of the republic of tatarstan. Kazan medical journal. 2010. Vol. 91(5): 594-598 (in Russian).
36. N.L. Blatt, M.E. Yalvac, A.K. Shafigullina, I.I. Salafutdinov, A.P. Kiyasov, R.E. Masgutov, Y.G. Shtirlin, A.V. Kabanov, A.A. Rizvanov. Effect of Pluronic Р85 on proliferation and osteogenic differentiation of human mesenchymal stem cells in vitro. Cellular transplantology and tissue engineering. 2010. Vol. 5(3): 66-70. (in Russian).
37. Rizvanov A.A., Yalvaç M.E., Shafigullina A.K., Salafutdinov I.I., Blatt N.L., Sahin F., Kiyasov A.P., Palotás A. Interaction and self-organization of human mesenchymal stem cells and neuro-blastoma SH-SY5Y cells under co-culture conditions: a novel system for modeling cancer cell micro-environment. European Journal of Pharmaceutics and Biopharmaceutics. 2010. Vol. 76(2): 253-259.
38. A. Palotás, H.J. Reis, G. Bogáts, B. Babik, M. Racsmány, L. Engvau, É. Kecskeméti, A. Juhász, L.B. Vieira, A.L. Teixeira, M.A. Mukhamedyarov, A.A. Rizvanov, M.E. Yalvaç, M.M. Guimarães, D. Rechanik, A.L. Zefirov, A.P. Kiyasov, R.K. Jourjikiya, L. Wang, Z. Janka, J. Kálmán. Coronary artery bypass surgery provokes Alzheimer’s disease-like changes in the cerebro-spinal fluid. Journal of Alzheimer Disease. 2010. Vol. 21 (4): 1153-1164.
39. I.I. Salafutdinov, A.K. Shafigullina, M.E. Yalvac, N.V. Kudryashova, M.A. Lagarkova, M.V. Shutova, S.L. Kiselev, R.F. Masgutov, R.I. Zhdanov, A.P. Kiyasov, R.R. Islamov, A.A. Rizvanov. Effect of simultaneous expression of various usoforms of vascular endothelial growth factor VEGF and fibroblast growth factor FGF2 on proliferation of human umbilical cord blood cells HUVEC. Cellular transplantology and tissue engineering. 2010. Vol. 5(2): 62-67. (in Russian).
40. D. Andreeva, I. Gazizov, T. Ilmaz, M. Kaligin, A. Gumerova, A. Kiyasov, A. Rizvanov. Differentiation of transfected human umbilical cord blood stem cells in the regenerating liver of rats. Journal of Hepatology. 2010 Vol. 52, Sup. 1:353-354.
41. Reis HJ, Mukhamedyarov MA, Rizvanov AA, Palotás A. A New Story about an Old Guy: Is Alzheimer's Disease Infectious? Neurodegener Dis. 2010 May 27; 7(4): 272-278.
42. Yalvaç ME, Ramazanoglu M, Tekguc M, Bayrak OF, Shafigullina AK, Salafutdinov II, Blatt NL, Kiyasov AP, Sahin F, Palotás A, Rizvanov AA. Human tooth germ stem cells preserve neuro-protective effects after long-term cryo-preservation. Curr Neurovasc Res. 2010 Feb 1;7(1):49-58.
43. Lagarkova MA, Shutova MV, Bogomazova AN, Vassina EM, Glazov EA, Zhang P, Rizvanov AA, Chestkov IV, Kiselev SL. Induction of pluripotency in human endothelial cells resets epigenetic profile on genome scale. Cell Cycle. 2010. Mar 6;9(5): 937-946.
44. Yalvac ME, Ramazanoglu M, Rizvanov AA, Sahin F, Bayrak OF, Salli U, Palotás A, Kose GT. Isolation and characterization of stem cells derived from human third molar tooth germs of young adults: implications in neo-vascularization, osteo-, adipo- and neuro-genesis. Pharmacogenomics Journal. 2010 Apr;10(2):105-13.
45. Reis HJ, Mukhamedyarov MA, Rizvanov AA, Palotás A. In the Name of Science: Don't Tamper with the Deceptive Truth. Mini Rev Med Chem. 2009 Dec 1;9(14):1633-8.
46. Yalvac ME, Rizvanov AA, Kilic E, Sahin F, Mukhamedyarov MA, Islamov RR, Palotás A. Potential role of dental stem cells in the cellular therapy of cerebral ischemia. Current Pharmaceutical Design. 2009;15(33):3908-16.
47. Rizvanov A.A. Bone-marrow adipocytes as negative regulators of the haematopoietic microenvironment. Cellular transplantology and tissue engineering. 2009. Vol. 4(3): 31-32. (Review in Russian).
48. Mikhailova EO, Balaban NP, Mardanova AM, Rudakova NL, Ilyinskaya ON, Rudenskaya GN, Rizvanov AA, Sharipova MR. Purification of a subtilisin-like serine proteinase from recombinant Bacillus subtilis during different phases of growth. Annals of Microbiology. 2009. Vol. 59, Issue: 2, Pages: 301-307.
49. Rizvanov AA, Mukhamedyarov MA, Palotás A, Islamov RR. Retrogradely transported siRNA silences human mutant SOD(1) in spinal cord motor neurons. Exp Brain Res. 2009 May;195(1):1-4.
50. Yalvac ME, Ramazanoglu M, Gumru OZ, Sahin F, Palotás A, Rizvanov AA. Comparison and Optimisation of Transfection of Human Dental Follicle Cells, a Novel Source of Stem Cells, with Different Chemical Methods and Electro-poration. Neurochem Res. 2009 Jul;34(7):1272-7.
51. R.P. Naumova, T.V. Grigoryeva, A.A. Rizvanov, J.V. Gogolev, N.V. Kudrjashova, A.V. Laikov. Diazotrophs Originated from Petrochemical Sludge as a Potential Resource of Waste Remediation. World Applied Sciences Journal. 2009 Vol.6 (2): P.154-157
52. T.I. Abdullin, O.V. Bondar, A.A. Rizvanov, I.I. Nikitina. Carbon nanotubes based biosensors for DNA structure characterization // Applied Biochemistry and Microbiology. 2009. – Vol. 45. – №2. – P.229–232.
53. V.A. Anokhin, E.V. Golovin, A.A. Rizvanov. The preintegration complex of human immunodeficiency virus as a potential object of gene therapy for HIV infection // Infectious diseases (Russian) – 2008. – V.6. - №4. – P.46-50.
54. R.R. Islamov, A.A. Rizvanov, A.P. Kiyasov Strategy in gene-stem cell therapy of amyotrophic lateral sclerosis // Neurological Bulletin. 2008. – V.40. – №4. – P.91-101.