Weston Family Microbiome Initiative - Letter of Intent

Please use size 11 Font (Arial, Times, Calibri are acceptable), single-spaced.

  • LOI must be submitted as a Microsoft Word document (doc, docx, etc.).
  • Mandatory file naming convention: Last name, First initial - POP LOI, 2018.docx
  • Please see the Program Details document for information on Review Criteria.
  • Applicants are encouraged to concise in completing each section.
  • Completed LOIs should be submitted to
  • Application deadline March 21st, 2018 at 2:00 pm EST.

Program Stream: 1) Prebiotics 2) Probiotics, Postbiotics (please indicate by highlighting)

Principal Applicant:

Project Title:

Project Team:

Full Name

/ Salutation: / First: / Last:

Title

Institution(s)

Address

/ Room/Building: / Street Name:
City: / Province: / Postal Code:

Telephone

E-mail

Project Role

% Time on Project

FullName

/ Salutation: / First: / Last:

Title

Institution (s)

Address

/ Room/Building: / Street Name:
City: / Province: / Postal Code:

Telephone

E-mail

Project Role

% Time on Project

FullName

/ Salutation: / First: / Last:

Title

Institution(s)

Address

/ Room/Building: / Street Name:
City: / Province: / Postal Code:

Telephone

E-mail

Project Role

% Time on Project

Keywords to describe the proposed project(Max. 6)
Is amodel or therapeutic being developed as the main goal of the project?If so, please indicate.
(Please select all that apply)
Model/tool
Animal model*
Biomarker
Clinical assessment instruments
Diagnostic
New method of drug delivery
Other (Please specify below) / Therapeutic
Probiotic
Prebiotic
Postbiotic
Engineered Microbes
Microbial Transplant
Other (Please specify below)
Other:
*NBAnimal research that would be acceptable to the Trust is that in small mammals only,for example mice, rats and guinea pigs.
Have you applied to other funding agencies with the same proposed work?
(This information will not be used to assess the application) / Yes Please specify:
No
Is this your first application for a research grant in microbiome research?
(This information will not be used to assess the application) / Yes
No
Please list the full name of Canadian or international researchers who are competitive with you and therefore should not review your application. Please do not exclude reviewers for other reasons, as we are unable to honor these requests. Note that the majority of the members on the scientific review committee are international.
  1. Goals and Specific Aims of the Project (Max. 200 Words)

What are the objectives of the project and how do they relate to translational research towards microbiome-based health applications?

  1. Background and Significance (Max. 200 Words)

Why is it important that the proposed project be carried out? Please critically evaluate existing knowledge and identify the gaps that this project is intended to fill.

  1. Experimental Approach (Max. 400 Words)

How will the proposed project be conducted? Please include: central hypothesis, experimental methods to address the specific objectives presented in Section 1, preliminary data (if applicable), and any considerations and contingencies at critical milestones. Applicants are encouraged to be concise. One page of preliminary data may be appended at the end of this document (optional).

  1. Future Directions and Applications (Max. 200 Words)

How will a successful outcome influence the development of Microbiome-based health applications? Provide a high-level overview of the future work, timeline and capital required to realize application.

  1. Relevant publications (cited or directly relevant)

Publications can be used to support rationale for the project and methodology, provide additional background and/or demonstrate expertise of the applicant where suitable. Please provide in the following format including full list of authors and PMID:

1)Foster LM, Tompkins TA, Dahl WJ. A comprehensive post-market review of studies on a probiotic product containing Lactobacillus helveticusR0052 and Lactobacillus rhamnosusR0011. Benef Microbes, 2011. 1;2(4):319-34. PMID:22146691.
  1. Preliminary Data (single page,optional)

1