Curriculum Vitae Aftab Nadeem

Aftab Nadeem, PhD Student

Date of birth: October 10th 1984

Swedish Personummer: 19841010-4692

Citizenship: Pakistan

Gender: Male

Marital Status: Married

Home Address: Kämnärsvägen 37K, 22646, Lund, Sweden

Work Address: Institute of Laboratory Medicine, Division MIG, Solvegatan 23, Box 117, 22100, Lund, Sweden

Home / Mobile Ph.: +46762373504

E-mail: /

EDUCATION

March 2013, PhD Biomedicine (Cancer Therapeutics)

Catharina Svanborg’s Lab, Department of Microbiology, Immunology and Glycobiology, Institute of Laboratory Medicine, Lund University, Sweden

Project: Molecular mechanisms involved in HAMLET induced tumor cell death

2011-2012, Masters in Molecular Biology

Skövde University, Sweden (Passed with distinction, VG)

Major: Molecular Biology and Genetic Engineering, Infection and Diseases

2007-2009, Masters in Biochemistry

University of Lahore, Pakistan (3.82/4.0 cGPA)

Major: Biochemistry, Physiology and Molecular Biology

RELEVANT WORK EXPERIENCE

2011-2013 Project Assistant at Department of Microbiology, Immunology and Glycobiology, Institute of Laboratory Medicine, Lund University, Sweden.

2009-2010 Medical Technologist, Shaukat Khanum Memorial Cancer Hospital & Research Centre (SKMCHRC).

2008 Project assistant at Food and Biotechnology Research Center, Pakistan Council of Scientific and Industrial Research, Pakistan.

RESEARCH SKILLS

Cellular and Molecular Biology, Microbiology and Immunology, Confocal Microscopy, Protein-Protein Interaction, Biotechnology and Genetic Engineering, Bioinformatics (at beginner level) and Cell Culture Techniques.

HONOURS

Recipient of international travel award from Kungliga Fysiografiska Sällskapet i Lund, Sweden to participate and present research findings at the Society of Mucosal Immunology (SMI) to be held in Toronto, Canada, 2016.

Recipient of Project grant from Kungliga Fysiografiska Sällskapet i Lund, Sweden. 2016.

Recipient of international travel award from the Faculty of Medicine, Lund University (Sweden) for collaborating research at the Department of Biomedical Engineering and Chemical Engineering and Material Science, University of California, USA, 2015

PUBLISHED PEER-REVIEWED ARTICLES (In chronological order)

1.  Puthia, M., Ambite, I., Cafaro, C., Butler, D., Huang, Y., Lutay, N., Rydström, G., Gullstrand, B., Swaminathan, B., Nadeem A, Nilsson, B., Svanborg, C (2016). IRF7 inhibition prevents destructive innate immunity - a target for non-antibiotic therapy of bacterial infections.

Science Translational Medicine. 8(336):336ra59.

2.  Nadeem A, Sanborn J, Gettel DL, Ho JCS, Rydström A, Ngassam VN, Klausen TK, Pedersen SF, Lam M, Parikh AN and Svanborg C (2015). Protein receptor-independent plasma membrane remodeling by HAMLET; a tumoricidal protein-lipid complex.

Scientific Reports. 5:16432. doi: 10.1038/srep16432.

3.  Ho JCS, Nadeem A, Rydström, A, Puthia M and Svanborg C (2015). Targeting of nucleotide-binding proteins by HAMLET - a conserved tumor cell death mechanism.

Oncogene. doi: 10.1038/onc.2015.144.

4.  Ho JCS, Sielaff H, Nadeem A, Svanborg C and Gruber G. The molecular motor F-ATP synthase is targeted by the tumoricidal protein HAMLET (2015). Journal of Molecular Biology. doi: 10.1016/j.jmb.2015.01.024.

5.  Puthia M, Storm P, Nadeem A, Hsiung S, Svanborg C. Prevention and treatment of colon cancer by peroral administration of HAMLET (human α-lactalbumin made lethal to tumour cells) (2013). Gut. 63(1): 131-142.

6.  Lutay, N., Ambite I, Grönberg-Hernandez J, Rydström G, Ragnarsdottir B, Puthia M, Nadeem A, Zhang, J, Storm, P, Dobrindt U, Wullt, B and Svanborg C (2013). Bacterial control of host gene expression through RNA polymerase II. Journal of Clinical Investigation. 123: 2366-79.

7.  Ho JCS,Rydström A,Trulsson M,Bålfors J,Storm P,Puthia M,Nadeem A,Svanborg C. HAMLET: functional properties and therapeutic potential. (2012) Future Oncology. 8(10):1301-13. doi: 10.2217/fon.12.122.

8.  Godaly G, Ambite I, Puthia M, Nadeem A, Ho J, Nagy K, Huang Y, Rydström G, Svanborg C (2016). Urinary Tract Infection Molecular Mechanisms and Clinical Translation.

Pathogens. 24;5(1). pii: E24. doi: 10.3390/pathogens5010024.

9.  Nadeem A, Syed Q, Baig S, Irfan M and Nadeem M (2010). Enhanced Production of Citric Acid by Aspergillus niger M-101 using Lower Alcohols. Turk. J. Biochem, 35 (1): 7-13.

10.  Nadeem A, SA Jafri, S Baig, M Irfan, Q Syed (2009). Optimization of Substrate Concentration for Enhanced Citric Acid Production using Aspergillus niger M-101. Pak. J. Sci. Ind. Res, 52(4): 275-277.

11.  Nadeem A, SA Jafri, S Baig, Ali J, Irfan M and Nadeem M (2009). Effect of Temperature on Production of Citric Acid Using Aspergillus niger PTCC-10. Pak. J. Biochem and Mol Biol. 34 (2): 273-276.

12.  Jafri SA, Hasan SS, Nadeem A, Kalsoom and Iqbal J (2011). Hypoglycemic Effects of Aloe vera Extract in Alloxan-induced Diabetic Albino Rats. Med. J Isl. W. Acad. Sci. 19 (3): 115-116.

13.  Khurram MM, Jafri SA, Mannan A, Nadeem A and Jamal A (2010). Frequency Of Aberrant Expression of CD Markers in Cases of Acute Leukemia. Med. J Isl. W. Acad. Sci. 18 (2): 55-60.

Conferences

3rd HAMLET Conference, Lund, Sweden (December 7-8, 2012). Poster presentation. Suppression of b-catenin signaling in human colon cancer cells in response to HAMLET.

II International Frontiers in Oncology, (Pamplona, SPAIN), (October 5-7, 2015). Poster presentation. Targeting of nucleotide-binding proteins by HAMLET - a conserved tumor cell death mechanism