Selection and ranking method for Currently Used Pesticides (CUPs)monitoring in ambient air

Arnaud Giusti, Catherine Pirard, Corinne Charlier, Jérôme C.J. Petit, Sophie Crevecoeur & Suzanne Remy

Address:

Arnaud Giusti, Jérôme C.J. Petit,Sophie Crevecoeur, Suzanne Remy: InstitutScientifique de Service Public (ISSeP), Direction of Chronic Risks, Environment and Health team, 4000 Liège, Belgium

Catherine Pirard, Corinne Charlier: Laboratory of Clinical, Forensic and Environmental Toxicology, University of Liege (ULg), CHU (B35), 4000 Liege, Belgium

Number of supplementary tables: 3

Table S.1: CUPs representing 95 % of total amount sold in Belgium between 2010 and 2013 and their proportion to the total amount

Currently Used Pesticides / Proportion of total amount sold in Belgium between 2010 and 2013 / Currently Used Pesticides / Proportion of total amount sold in Belgium between 2010 and 2013 / Currently Used Pesticides / Proportion of total amount sold in Belgium between 2010 and 2013
mancozeb / 16,91% / chlorpyrifos / 0,67% / mecoprop-P / 0,36%
glyphosate / 11,27% / boscalid / 0,63% / epoxiconazole / 0,35%
chlormequat / 4,02% / dithianon / 0,62% / metazachlor / 0,35%
metam-sodium / 3,56% / thiophanate-methyl / 0,62% / metaldehyde / 0,34%
captan / 3,40% / mandipropamid / 0,60% / azoxystrobin / 0,33%
metamitron / 3,07% / fosetyl / 0,59% / prochloraz / 0,30%
thiram / 3,02% / maleic hydrazide / 0,59% / cyprodinil / 0,29%
propamocarb / 2,94% / ethephon / 0,55% / methiocarb / 0,29%
prosulfocarb / 2,75% / fluroxypyr / 0,54% / difenoconazole / 0,28%
terbuthylazine / 2,62% / fenpropimorph / 0,53% / mesotrione / 0,27%
MCPA / 2,40% / fluazinam / 0,49% / propyzamide / 0,27%
chlorothalonil / 1,98% / spiroxamine / 0,48% / asulam / 0,26%
dimethenamid-P / 1,73% / dichlorprop-P / 0,47% / dimethomorph / 0,26%
S-metolachlor / 1,61% / oxadiazon / 0,47% / pethoxamide / 0,26%
isoproturon / 1,54% / cyazofamid / 0,46% / sulcotrione / 0,24%
aclonifen / 1,37% / 2,4-D / 0,44% / triallate / 0,23%
chloridazon / 1,34% / metribuzin / 0,43% / mepiquat chloride / 0,23%
flufenacet / 1,29% / chlorotoluron / 0,42% / maneb / 0,22%
ethofumesate / 1,11% / benfluralin / 0,42% / fenpropidin / 0,21%
chlorpropham / 1,09% / amitrole / 0,42% / pyraclostrobine / 0,20%
diquat / 1,05% / carbetamide / 0,41% / clopyralid / 0,20%
phenmedipham / 1,04% / dimethoate / 0,41% / trinexapac-ethyl / 0,19%
metam-potassium / 1,01% / iprodione / 0,40% / pirimicarb / 0,18%
linuron / 0,92% / bentazone / 0,40% / trifloxystrobine / 0,18%
pendimethalin / 0,90% / tebuconazole / 0,40% / fluopicolide / 0,17%
cymoxanil / 0,83% / diflufenican / 0,37%
prothioconazole / 0,67% / dodine / 0,37%

Table S.2:53 CUPs with at least 3 suspected or proved toxicological endpoint reported in at least one database

Currently Used Pesticides / carcinogenicity / neurotoxicity / endocrine disruption / developmental and reproductive toxicity / genotoxicity and mutagenicity
amitrole / X / X / X / X / X
dimethoate / X / X / X / X / X
mancozeb / X / X / X / X / X
metiram / X / X / X / X / X
thiophanate-methyl / X / X / X / X / X
thiram / X / X / X / X / X
2,4-D / X / X / X / X
carbendazim / X / X / X / X
cypermethrin / X / X / X / X
esfenvalerate / X / X / X / X
fenoxycarb / X / X / X / X
fluazinam / X / X / X / X
iprodione / X / X / X / X
isoxaflutole / X / X / X / X
maneb / X / X / X / X
MCPA / X / X / X / X
metaldehyde / X / X / X / X
prochloraz / X / X / X / X
propiconazole / X / X / X / X
spirodiclofen / X / X / X / X
tefluthrin / X / X / X / X
triadimenol / X / X / X / X
zeta-cypermethrin / X / X / X / X
2,4-DB / X / X / X
alpha-cypermethrin / X / X / X
beta-cyfluthrin / X / X / X
bromoxynil / X / X / X
chlorpropham / X / X / X
chlorpyrifos / X / X / X
clofentezine / X / X / X
cymoxanil / X / X / X
deltamethrin / X / X / X
dicamba / X / X / X
dichlorprop-P / X / X / X
diethofencarb / X / X / X
flufenacet / X / X / X
fluquinconazole / X / X / X
flusilazole / X / X / X
fluxapyroxad / X / X / X
imidacloprid / X / X / X
indoxacarb / X / X / X
linuron / X / X / X
metam-potassium / X / X / X
metam-sodium / X / X / X
pendimethalin / X / X / X
pymetrozine / X / X / X
pyrimethanil / X / X / X
tebuconazole / X / X / X
tetraconazole / X / X / X
thiabendazole / X / X / X
thiacloprid / X / X / X
thiamethoxam / X / X / X
triallate / X / X / X

Table S.3: Total points attributed to the 66 CUPs ranked in at least one top 60 list established using each of the 3 methodsused to test the robustness of the ranking

Currently Used Pesticides / Total points ranking method 1 (max. 48) / Total points ranking method 2 (max. 58) / Total points ranking method 3 (max. 61) / Number of time classified in the top 60 lists
chlorothalonil / 38 / 41 / 48 / 3
cymoxanil / 37 / 43 / 49 / 3
fluazinam / 37 / 44 / 47 / 3
MCPA / 37 / 45 / 44 / 3
2,4-D / 36 / 42 / 43 / 3
epoxiconazole / 36 / 39 / 45 / 3
mecoprop-P / 36 / 39 / 47 / 3
pendimethalin / 36 / 41 / 48 / 3
tebuconazole / 36 / 40 / 43 / 3
dimethenamid-P / 35 / 37 / 44 / 3
linuron / 35 / 40 / 42 / 3
prochloraz / 35 / 42 / 42 / 3
propiconazole / 35 / 41 / 41 / 3
terbuthylazine / 35 / 39 / 46 / 3
cypermethrin / 34 / 41 / 42 / 3
fenpropimorph / 34 / 35 / 46 / 3
mancozeb / 34 / 42 / 33 / 3
chlorpyrifos / 33 / 39 / 46 / 3
dimethoate / 33 / 43 / 41 / 3
deltamethrin / 32 / 38 / 42 / 3
diflufenican / 32 / 33 / 41 / 3
ethofumesate / 32 / 35 / 44 / 3
prosulfocarb / 32 / 30 / 42 / 3
S-metolachlor / 32 / 35 / 44 / 3
tri-allate / 32 / 37 / 43 / 3
flufenacet / 31 / 36 / 31 / 3
aclonifen / 30 / 34 / 40 / 3
difenoconazole / 30 / 33 / 35 / 3
iprodione / 30 / 37 / 37 / 3
isoproturon / 30 / 31 / 36 / 3
oxadiazon / 30 / 33 / 42 / 3
boscalid / 29 / 32 / 34 / 3
dichlorprop-P / 29 / 35 / 37 / 3
flusilazole / 29 / 34 / 38 / 3
glyphosate / 29 / 33 / 38 / 3
metaldehyde / 29 / 36 / 31 / 3
spiroxamine / 29 / 28 / 41 / 3
thiram / 29 / 39 / 30 / 3
alpha-cypermethrin / 28 / 33 / 35 / 3
chlorpropham / 28 / 34 / 35 / 3
tetraconazole / 28 / 33 / 37 / 3
captan / 27 / 29 / 38 / 3
dimethomorph / 27 / 28 / 36 / 3
fenoxycarb / 27 / 35 / 37 / 3
fenpropidin / 27 / 29 / 39 / 3
metribuzin / 27 / 31 / 34 / 3
phenmedipham / 27 / 29 / 32 / 3
pirimicarb / 27 / 31 / 38 / 3
prothioconazole / 27 / 30 / 27 / 3
trifloxystrobine / 27 / 27 / 33 / 2
azoxystrobin / 26 / 26 / 31 / 2
cyprodinil / 26 / 27 / 38 / 2
dicamba / 26 / 32 / 33 / 3
metazachlor / 26 / 27 / 35 / 2
clopyralid / 25 / 27 / 30 / 2
metamitron / 25 / 29 / 26 / 2
pyrimethanil / 25 / 31 / 36 / 3
thiophanate-methyl / 25 / 33 / 24 / 2
amitrole / 24 / 34 / 24 / 2
beta-cyfluthrin / 24 / 29 / 29 / 3
bromoxynil / 24 / 30 / 32 / 2
carbendazim / 24 / 31 / 27 / 2
chlorotoluron / 24 / 26 / 27 / 1
fluroxypyr / 24 / 28 / 24 / 1
2,4-DB / 23 / 28 / 25 / 1