Priya Thomas, T.V. Vineeth Kumar, V. Reshmy, K.S. Kumar and S. George*

A Mini Review on the Antimicrobial Peptides Isolated from the Genus Hylarana (Amphibia:Anura) with a Proposed Nomenclature for Amphibian Skin Peptides

Priya Thomas, T.V. Vineeth Kumar, V. Reshmy, K.S. Kumar and S. George*,

Chemical Biology Group, Rajiv Gandhi Centre for Biotechnology (RGCB),

Thiruvananthapuram-695014, Kerala, India.

*Corresponding author

Dr. Sanil George

Email:

Mobile: 09495568945

Phone: + 91-471-2529530

Fax: + 91- 471-2348096

Table. S1 Sequence and existing nomenclature of peptide isolated from the skin of frogs of different species belonging to Hylarana genus

Species / Peptide / Sequence / Ref
Brevinin
H. erythrea / Brevinin-2ERa / GVVKDTLKSVAKTVALQLVNTAKCKLEKTC / [9]
Brevinin-2ERb / GAIKETLKDFAKTVALGLVNTAKCKLEKTC / [9]
Brevinin-1ERa / FLPGLIKVAAGLIPKVVCKFTNKC / [9]
Brevinin-1ERb / FLPTLIKVAANVIPSIICKFTGKC / [9]
Brevinin-1ERc / FLPTLIKVAADVIPSIICKFTGKC / [9]
B2RP-ERa / GVIKSVLKGVAKTVALGML / [9]
H. latouchii / Brevinin-1LTa / FFGTALKIAANVLPTAICKILKKC / [12]
Brevinin-1LTb / FFGTALKIAANILPTAICKILKKC / [12]
Brevinin-1LT1 / FMGSALRIAAKVLPAALCQIFKKC / [13]
Brevinin-1LT2 / FFGSVLKVAAKVLPAALCQIFKKC / [13]
H. picturata / Brevinin-2PTa / PVIDPTHRINDRDYMGWMDF / [17]
Brevinin-2PTb / GFKGAFKNVMFGIAKSAGKSALNALACKIDKSC / [17]
Brevinin-2PTc / GLLDSFKNAMIGIAKSAGKTALNKIACKIDKTC / [17]
Brevinin-2PTd / GFLDSFKNAMIGVAKSAGKTALNTLACKIDKTC / [17]
Brevinin-2PTe / GFLDSFKNAMIGVAKSVGKTALSTLACKIDKSC / [17]
Brevinin-1PTa / FMGGLIKAATKIVPAAYCAITKKC / [17]
Brevinin-1PTb / FMGGLIKAATKALPAAFCAITKKC / [17]
H. guentheri / Brevinin-2GHa / GFSSLFKAGAKYLLKSVGKAGAQQLACKAANNCA / [11]
Brevinin-2GHb / GVITDALKGAAKTVAAELLRKAHCKLTN / [11]
Brevinin-2GHc / SIWEGIKNAGKGFLVSILDKVRCKVAGGCNP / [11]
Brevinin-2GUa / GVITDALKGAAKTVAAELLRKAHCKLTNSC / [10]
Brevinin-2GUb / GVIIDTLKGAAKTVAAELLRKAHCKLTNSC / [10]
Brevinin-2GUc / GVITDTLKGVAKTVAAELLRKAHCKLTNSC / [10]
Brevinin-1GUa / FLGALFKVTSKLVPAAICSISKKC / [10]
Brevinin-1GUb / FLGALFKVASKLVPAAICSISKKC / [10]
H. temporalis / Brevinin-1TEa / FFGPLIKIATGVLPNLICKALGKC / [18]
Brevinin-2TEa / GIGSMLLGLAKNVGMSLLNKAQCKISGKC / [18]
Brevinin-2TEb / GFMGDTLKGIARNAALALMNAAQCKLSGKC / [18]
Esculentin
H. erythrea / Esculentin-2ERa / GLFSLFKAGAKILGKTFLKQAGKAGAEHLACKAANQC / [9]
Esculentin-2ERb / GILNTLKNVGLGVLKGAGKGALNAVLCKMNNNC / [9]
Esculentin-2ERc / GILNTLKNVGLGVLKSAGKGALNAVLCKMNNSC / [9]
Esculentin-2ERd / SILTTLKDVGISVAKAAGSGVLKALLCKLLCKLNKNCEA / [9]
H. temporalis / Esculentin-2TEa / GLFSILKIGAKVIGKNLLKQAGKAGMEYAACKATNQC / [20]
Esculentin-2TEb / GLFSILKIGAEVIGKNLLKQAGKAGMEYAACKAANQC / [20]
Esculentin-2TEc / GLFSILKIGAKVIGKSLLKQAGKAGMEYAACKATNQC / [20]
Species / Peptide / Sequence / Ref
Temporin
H. erythrea / Temporin-ERa / FLPLIIGALSSLLPKIF / [9]
H. latouchii / Temporin-LTa / FFPLVLGALGSILPKIF / [12]
Temporin-LTb / FIITGLVRGLTKLF / [12]
Temporin-LTc / SLSRFLSFLKIVYPPAF / [12]
Temporin-LT1 / FLPGLIAGIAKML / [13]
Temporin-LT2 / FLPIALKALGSIFPKIL / [13]
H.nigrovittata / Temporin-RN1 / FLPLVLGALSGILPKIL / [16]
Temporin-RN2 / FFPLLFGALSSLLPKLF / [16]
Temporin-RN3 / FFPLLFGALSSHLPKLF / [16]
H. picturata / Temporin-PTa / FFGSVLKLIPKIL / [17]
H. guentheri / Temporin-GH / FLPLLFGAISHLL / [11]
Temporin-GUb- (1 -6) / FLPLLF / [10]
Temporin -GUa / FLQHIIGALSHIF / [10]
Temporin-GUc-(1-6) / FFPLIF / [10]
Temporin-GUb / FLPLLFGAISHIL / [10]
Temporin -GUc / FFPLIFGALSSILPKIL / [10]
Nigroain
H. nigrovittata / Nigroain-B1 / CVISAGWNHKIRCKLTGNC / [16]
Nigroain-B2 / CVISAGWDHKVRCKLTGNC / [16]
Nigroain-B3 / CKIALPYHMRCRVLGRC / [16]
Nigroain-B4 / CVISAGWNHKIR / [16]
Nigroain-B5 / CKIALPYT / [16]
Nigroain-C1 / FKTWKRPPFQTSCSGIIKE / [16]
Nigroain-C2 / FKTWKRPPFQTSCWGIIKE / [16]
Nigroain-D1 / CVHWQTNPARTSCIGP / [16]
Nigroain-D2 / CVHWQTNPARTSRIGP / [16]
Nigroain-D3 / CVHWQTNTARTSCIGP / [16]
Nigroain-E1 / DCTRWIIGINGRICRD / [16]
Nigroain-E2 / GCTQWINNIHGRICVRN / [16]
Nigroain-I / SFLSKFKDIALDVPRMRARVY / [16]
Nigroain-K1 / SLWETIKNAGKGFIQNILDKIR / [16]
Nigroain-K2 / SLWETIKNAGKGFILNILDKIRCKVAGGCKT / [16]
Gaegurin
H. nigrovittata / Gaegurin-RN1 / FIGPVLKIAAGILPTAICKIFKKC / [16]
Gaegurin-RN2 / FIGPVLKIATSILPTAICKIFKKC / [16]
Gaegurin-RN3 / FLGPIIKIATGILPTAICKILKKC / [16]
Gaegurin-RN4 / FVGPVLKIAAGILPTAICKIYKKC / [16]
Gaegurin-RN5 / FLGPIIKIATGILPTAICKFLKKC / [16]
Gaegurin-RN6 / FLGPIIKIATGILPTAICKILKKMLKLWKWKSSDVEYHLAKCTSDVL / [16]
Gaegurin-RN7 / FLGPIIKIATGILPTAICKILKNVETLEMEII / [16]
Rugosin
H. nigrovittata / Rugosin-RN1 / SIRDKIKTIAIDLAKSAGTGVLKTLICKLDKSC / [16]
Rugosin-RN2 / SIRDKIKTIAIDLAKGAGTGVLKTLICKLDKSC / [16]
Rugosin-RN3 / SIRDKIKTIAIDLAKSAGMGILKTLICKLDKSC / [16]
Rugosin-RN4 / SIRDKIKTIAIDLAKSAGTGVLKTSICKLDKSC / [16]
Rugosin-RN5 / SIRDKIKTIAIDLAKSAGTGVLKTLICKLNKSC / [16]
Rugosin-RN6 / SFLSKFKDIALDVAKNAGKGVLTTLACKIDGSC / [16]
Rugosin-RN7 / RFLSKFKDIALDVAKNAGKGVLTTLACKIDGSC / [16]
Rugosin-RN8 / SFLSKFKDIALDVAKNAGKGVLTTLARKIDGSC / [16]
Rugosin-RN9 / SFLSKIKDIALDVAKNAGKGVLTTLACKIDGSC / [16]
Guentherin
H. guentheri / Guentherin / VIDDLKKVAKKVRRELLCKKHHKKLN / [11]
Species / Peptide / Sequence / Ref
Hylaranakinin
H.temporalis / Hylaranakinin-1 / RPPGFSPFRFVPASSL / [19]
Hylaranakinin-2 / RPPGFTPFRFAPEII / [19]
Ranakinin N
H. nigrovittata / Ranakinin-N / RAEAVPPGFTPFR / [15]
Cholecystokinin
H. nigrovittata / Cholecystokinin / RVDGNSDQKAVIGAMLAKDLQTRKAGSSTGRYAVLPNR / [14]