Research outputs

Listing of Research outputs

Biochemistry and physiology of cardiac muscle

Nabeebaccus, A.Shah, A. M.Aug 2018In : Medicine (United Kingdom).46, 8, p. 431-4366 p.

Research output: Contribution to journal › Review article

Nox2 in regulatory T cells promotes angiotensin II–induced cardiovascular remodeling

Emmerson, A., Cellone Trevelin, S., Mongue-Din, H., Becker, P. D., Ortiz, C., Smyth, L. A., Peng, Q., Elgueta, R., Sawyer, G., Ivetic, A., Lechler, R. I., Lombardi, G.Shah, A. M.2 Jul 2018In : The Journal of Clinical investigation.128, 7, p. 3088–3101

Research output: Contribution to journal › Article

Biochemistry and physiology of cardiac muscle

Nabeebaccus, A.Shah, A. M.23 Jun 2018In : Medicine.42, 8, p. 413-4175 p.

Research output: Contribution to journal › Article

Reactive oxygen species regulate axonal regeneration through the release of exosomal NADPH oxidase 2 complexes into injured axons

Hervera, A., De Virgiliis, F., Palmisano, I., Zhou, L., Tantardini, E., Kong, G., Hutson, T., Danzi, M. C., Perry, R. B-T., Santos, C. X. C., Kapustin, A. N., Fleck, R. A., Del Río, J. A., Carroll, T., Lemmon, V., Bixby, J. L., Shah, A. M., Fainzilber, M. & Di Giovanni, S. 20 Mar 2018In : NATURE CELL BIOLOGY.20, 3, p. 307-31913 p.

Research output: Contribution to journal › Article

Oxygen gradients can determine epigenetic asymmetry and cellular differentiation via differential regulation of Tet activity in embryonic stem cells

Burr, S., Caldwell, A., Chong, M., Beretta, M., Metcalf, S., Hancock, M., Arno, M., Balu, S., Kropf, V. L., Mistry, R. K., Shah, A. M., Mann, G. E.Brewer, A. C.16 Feb 2018In : Nucleic Acids Research.46, 3, p. 1210-122617 p., gkx1197

Research output: Contribution to journal › Article

Drug treatment effects on outcomes in heart failure with preserved ejection fraction: a systematic review and meta-analysis

Zheng, S. L., Chan, . F. T., Nabeebaccus, A. A., Shah, A. M., McDonagh, T., Okonko, D. O.Ayis, S.12 Feb 2018In : Heart.104, 5, p. 407-415

Research output: Contribution to journal › Article

Inorganic Nitrite Selectively Dilates Epicardial Coronary Arteries

O'Gallagher, K., Khan, F., Omar, S. A., Kalra, S., Danson, E., Cabaco, A. R., Martin, K., Melikian, N., Shah, A. M.Webb, A. J.23 Jan 2018In : Journal of the American College of Cardiology.71, 3, p. 363-3642 p.

Research output: Contribution to journal › Article

Molecular imaging of cardiac remodelling after myocardial infarction

Curley, D., Lavin Plaza, B., Shah, A. M.Botnar, R. M.17 Jan 2018In : Basic Research in Cardiology.113, 2, 18 p., 10

Research output: Contribution to journal › Review article

Echocardiographic evaluation of diastolic function in mouse models of heart disease

Schnelle, M., Catibog, N., Zhang, M., Nabeebaccus, A. A., Anderson, G., Richards, D. A., Sawyer, G., Zhang, X., Toischer, K., Hasenfuss, G., Monaghan, M. J.Shah, A. M.1 Jan 2018In : Journal of Molecular and Cellular Cardiology.114, p. 20-289 p.

Research output: Contribution to journal › Article

MRI with gadofosveset: A potential marker for permeability in myocardial infarction

Lavin, B., Protti, A., Lorrio, S., Dong, X., Phinikaridou, A., Botnar, R. M.Shah, A.2018In : Atherosclerosis.

Research output: Contribution to journal › Article

Modelling the complexity of heart failure with preserved ejection fraction

O'Gallagher, K.Shah, A. M.2018In : Cardiovascular Research.114, 7, p. 919-921

Research output: Contribution to journal › Editorial

NADPH Oxidase-4 Driven Cardiac Macrophage Polarization Protects Against Myocardial Infarction–Induced Remodeling

Mongue-Din, H., Patel, A. S., Looi, Y. H., Grieve, D. J., Anilkumar, N., Sirker, A., Dong, X., Brewer, A. C., Zhang, M., Smith, A.Shah, A. M.25 Dec 2017In : JACC: Basic to Translational Science.2, 6, p. 688-69811 p.

Research output: Contribution to journal › Article

Nox4 reprograms cardiac substrate metabolism via protein O-GlcNAcylation to enhance stress adaptation

Nabeebaccus, A. A., Zoccarato, A., Hafstad, A. D., Santos, C. X., Aasum, E., Brewer, A. C., Zhang, M., Beretta, M., Yin, X., West, J. A., Schröder, K., Griffin, J. L., Eykyn, T. R., Abel, E. D., Mayr, M.Shah, A. M.21 Dec 2017In : JCI Insight.2, 24

Research output: Contribution to journal › Article

FKBP8 protects the heart from hemodynamic stress by preventing the accumulation of misfolded proteins and endoplasmic reticulum-associated apoptosis in mice

Misaka, T., Murakawa, T., Nishida, K., Omori, Y., Taneike, M., Omiya, S., Molenaar, C., Uno, Y., Yamaguchi, O., Takeda, J., Shah, A. M.Otsu, K.10 Nov 2017In : Journal of Molecular and Cellular Cardiology.114, p. 93-104

Research output: Contribution to journal › Article

Both cardiomyocyte and endothelial cell Nox4 mediate protection against hemodynamic overload-induced remodelling

Zhang, M., Mongue-din, H., Martin, D., Catibog, N., Smyrnias, I., Zhang, X., Yu, B., Wang, M., Brandes, R. P., Schröder, K. & Shah, A. M.13 Oct 2017In : Cardiovascular Research.

Research output: Contribution to journal › Article

Metabolically Activated Adipose Tissue Macrophages Perform Detrimental and Beneficial Functions during Diet-Induced Obesity

Coats, B. R., Schoenfelt, K. Q., Barbosa-Lorenzi, V. C., Peris, E., Cui, C., Hoffman, A., Zhou, G., Fernandez, S., Zhai, L., Hall, B. A., Haka, A. S., Shah, A. M., Reardon, C. A., Brady, M. J., Rhodes, C. J., Maxfield, F. R. & Becker, L. 26 Sep 2017In : Cell reports.20, 13, p. 3149-316113 p.

Research output: Contribution to journal › Article

The human coronary vasodilatory response to acute mental stress is mediated by neuronal nitric oxide synthase

Khan, S. G., Melikian, N., Shabeeh, H., Cabaco, A. R., Martin, K., Khan, F., O'Gallagher, K., Chowienczyk, P.Shah, A. M.23 Jun 2017In : AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY.

Research output: Contribution to journal › Article

Decoding NADPH Oxidase 4 Expression in Human Tumors

Meitzler, J. L., Makhlouf, H. R., Antony, S., Wu, Y., Butcher, D., Jiang, G., Juhasz, A., Lu, J., Dahan, I., Jansen-Dürr, P., Pircher, H., Shah, A. M., Roy, K. & Doroshow, J. H. 26 May 2017In : Redox Biology.13, p. 182–195

Research output: Contribution to journal › Article

Blood Pressure in Healthy Humans is Regulated by Neuronal NO Synthase

Shabeeh, H., Khan, S., Jiang, B., Brett, S., Melikian, N., Casadei, B., Chowienczyk, P. J.Shah, A. M.1 May 2017In : Hypertension.69, 5, p. 970-9767 p.

Research output: Contribution to journal › Article

Reduced First-Phase Ejection Fraction and Sustained Myocardial Wall Stress in Hypertensive Patients with Diastolic Dysfunction: A Manifestation of Impaired Shortening Deactivation That Links Systolic to Diastolic Dysfunction and Preserves Systolic Ejection Fraction

Gu, H., Li, Y., Fok, H., Simpson, J., Kentish, J., Shah, A.Chowienczyk, P.1 Apr 2017In : Hypertension.69, 4, p. 633-6408 p.

Research output: Contribution to journal › Article

Distinct Regulatory Effects of Myeloid Cell and Endothelial Cell Nox2 on Blood Pressure

Sag, C. M., Schnelle, M., Zhang, J., Murdoch, C. E., Kossmann, S., Protti, A., Santos, C. X. C., Sawyer, G. J., Zhang, X., Mongue-Din, H., Richards, D. A., Brewer, A. C., Prysyazhna, O., Maier, L. S., Wenzel, P., Eaton, P. J.Shah, A. M.28 Mar 2017In : Circulation (Baltimore).

Research output: Contribution to journal › Article

ECHOCARDIOGRAPHIC ESTIMATION OF MEAN PULMONARY ARTERY PRESSURE: A COMPARISON OF DIFFERENT APPROACHES TO PREDICT PULMONARY HYPERTENSION

Seidler, T., Hellenkamp, K., Unsöld, B., Mushemi-Blake, S., Shah, A. & Hasenfuss, G. 21 Mar 2017In : Journal of the American College of Cardiology.69, 11, Supplement, p. 18891 p.

Research output: Contribution to journal › Article

Selective Enhancement of Insulin Sensitivity in the Endothelium in Vivo Reveals a Novel Proatherosclerotic Signaling Loop

Viswambharan, H. , Yuldasheva, N. Y. , Sengupta, A. , Imrie, H. , Gage, M. C. , Haywood, N. , Walker, A. M. N. , Skromna, A. , Makova, N. , Galloway, S. , Shah, P. , Sukumar, P. , Porter, K. E. , Grant, P. J. , Shah, A. , Santos, C. X. , Li, J. , Beech, D. J. , Wheatcroft, S. B. , Cubbon, R. M. & 1 othersKearney, M. T.3 Mar 2017In : Circulation Research.120, 5, p. 784-79815 p.

Research output: Contribution to journal › Article

Hypoxia induces heart regeneration in adult mice

Nakada, Y. , Canseco, D. C. , Thet, S. , Abdisalaam, S. , Asaithamby, A. , Xavier Da Costa Dos Santos, C. S. , Shah, A. M. , Zhang, H. , Faber, J. E. , Kinter, M. T. , Szweda, L. I. , Xing, C. , Hu, Z. , Deberardinis, R. J. , Schiattarella, G. , Hill, J. A. , Oz, O. , Lu, Z. , Zhang, C. C. , Kimura, W. & 1 othersSadek, H. A.12 Jan 2017In : NATURE.541, 7636, p. 222-2276 p.

Research output: Contribution to journal › Article

PHD2 is a regulator for glycolytic reprogramming in macrophages

Guentsch, A., Beneke, A., Swain, L., Farhat, K., Nagarajan, S., Wielockx, B., Raithatha, K., Dudek, J., Rehling, P., Zieseniss, A., Jatho, A., Chong, M., Santos, C. X. C., Shah, A. M. & Katschinski, D. M. Jan 2017In : Molecular and Cellular Biology.37, 1, e00236-16

Research output: Contribution to journal › Article

A Novel α-Calcitonin Gene-Related Peptide Analogue Protects Against End-Organ Damage in Experimental Hypertension, Cardiac Hypertrophy and Heart Failure

Aubdool, A. A., Thakore, P., Argunhan, F., Smillie, S-J., Schnelle, M., Srivastava, S., Alawi, K. M., Wilde, E., Mitchell, J., Farrell-Dillon, K., Richards, D. A., Maltese, G., Siow, R. C., Nandi, M., Clark, J. E., Shah, A. M., Sams, A. & Brain, S. D.2017In : Circulation (Baltimore).136, p. 367-383

Research output: Contribution to journal › Article

Toll-like receptor 9 prevents cardiac rupture after myocardial infarction in mice independently of inflammation

Omiya, S., Omori, Y., Taneike, M., Protti, A., Yamaguchi, O., Akira, S., Shah, A., Nishida, K. & Otsu, K.Dec 2016In : American Journal of Physiology (Heart and Circulatory Physiology).311, 6, p. H1485-H1497

Research output: Contribution to journal › Article

Redox Imaging Using Cardiac Myocyte-Specific Transgenic Biosensor Mice

Swain, L., Kesemeyer, A., Meyer-Roxlau, S., Vettel, C., Zieseniss, A., Güntsch, A., Jatho, A., Becker, A., Nanadikar, M. S., Morgan, B., Dennerlein, S., Shah, A., El-Armouche, A., Nikolaev, V. O. & Katschinski, D. M. 14 Oct 2016In : Circulation Research.119, 9, p. 1004-101613 p.

Research output: Contribution to journal › Article

Apocynin and Nox2 regulate NF-κB by modifying thioredoxin-1 redox-state

Trevelin, S. C., Dos Santos, C. X., Ferreira, R. G., de Sá Lima, L., Silva, R. L., Scavone, C., Curi, R., Alves-Filho, J. C., Cunha, T. M., Roxo-Júnior, P., Cervi, M-C., Laurindo, F. R. M., Hothersall, J. S., Cobb, A. M., Zhang, M., Ivetic, A., Shah, A. M., Lopes, L. R. & Cunha, F. Q. 4 Oct 2016In : Scientific Reports.6, 34581

Research output: Contribution to journal › Article

CRISPR/Cas9-mediated knockout of p22phox leads to loss of Nox1 and Nox4, but not Nox5 activity

Prior, K-K., Leisegang, M. S., Josipovic, I., Löwe, O., Shah, A. M., Weissmann, N., Schröder, K. & Brandes, R. P. Oct 2016In : Redox Biology.9, p. 287–295

Research output: Contribution to journal › Article

Glycoproteomics Reveals Decorin Peptides with Anti-Myostatin Activity in Human Atrial Fibrillation

Barallobre-Barreiro, J. , Gupta, S. K. , Zoccarato, A. , Kitazume-Taneike, R. , Fava, M. , Yin, X. , Werner, T. , Hirt, M. N. , Zampetaki, A. , Viviano, A. , Chong, M. , Bern, M. , Kourliouros, A. , Domenech, N. , Willeit, P. , Shah, A. M. , Jahangiri, M. , Schaefer, L. , Fischer, J. W. , Iozzo, R. V. & 6 othersViner, R., Thum, T., Heineke, J., Kichler, A., Otsu, K.Mayr, M.13 Sep 2016In : Circulation (Baltimore).134, 11, p. 817-83216 p.

Research output: Contribution to journal › Article

Cell-specific effects of Nox2 on the acute and chronic response to myocardial infarction

Sirker, A., Murdoch, C. E., Protti, A., Sawyer, G. J., Santos, C. X. C., Martin, D., Zhang, X., Brewer, A. C., Zhang, M.Shah, A. M.Sep 2016In : Journal of Molecular and Cellular Cardiology.98, p. 11-177 p.

Research output: Contribution to journal › Article

Magnetic Drug Targeting: Preclinical in Vivo Studies, Mathematical Modeling, and Extrapolation to Humans

Al-Jamal, K. T., Bai, J., Tzu-Wen Wang, J., Protti, A., Southern, P., Bogart, L., Heidari, H., Li, X., Cakebread, A., Asker, D., Al-Jamal, W. T., Shah, A., Bals, S., Sosabowski, J. & Pankhurst, Q. A. 19 Aug 2016In : Nano Letters.16, 9, p. 5652-5660

Research output: Contribution to journal › Letter

Molecular mechanisms linking autonomic dysfunction and impaired cardiac contractility in critical illness

Ackland, G. L., Whittle, J., Toner, A., Machhada, A., Del Arroyo, A. G., Sciuso, A., Jenkins, N., Dyson, A., Struthers, R., Sneyd, J. R., Minto, G., Singer, M., Shah, A. & Gourine, A. V. 1 Aug 2016In : Critical Care Medicine.44, 8, p. e614-e624

Research output: Contribution to journal › Article

Potential Effect of Brexit on Cardiovascular Translational Science

Shah, A. M. & Mann, D. L. 1 Aug 2016In : JACC: Basic to Translational Science.1, 5, p. 416-4172 p.

Research output: Contribution to journal › Article

Heart failure-potential new targets for therapy

Nabeebaccus, A., Zheng, S. & Shah, A. M.30 Jun 2016In : British Medical Bulletin.119, 1, p. 99-110

Research output: Contribution to journal › Article

The Shortening of MWNT-SPION Hybrids by Steam Treatment Improves Their Magnetic Resonance Imaging Properties In Vitro and In Vivo

Cabana, L., Bourgognon, M., Wang, J. T. -W., Protti, A., Klippstein, R., de Rosales, R. T. M., Shah, A. M., Fontcuberta, J., Tobías-Rossell, E., Sosabowski, J. K., Al-Jamal, K. T. & Tobias, G. 15 Apr 2016In : Small.

Research output: Contribution to journal › Article

MTOR hyperactivation by ablation of tuberous sclerosis complex 2 in the mouse heart induces cardiac dysfunction with the increased number of small mitochondria mediated through the down-regulation of autophagy

Taneike, M., Nishida, K., Omiya, S., Zarrinpashneh, E., Misaka, T., Kitazume-Taneike, R., Austin, R., Takaoka, M., Yamaguchi, O., Gambello, M. J., Shah, A. M.Otsu, K.29 Mar 2016In : PL o S One .11, 3, e0152628

Research output: Contribution to journal › Article

The endoplasmic reticulum chaperone calnexin is a NADPH oxidase NOX4 interacting protein

Prior, K. K., Wittig, I., Leisegang, M. S., Groenendyk, J., Weissmann, N., Michalak, M., Jansen-Dürr, P., Shah, A. M. & Brandes, R. P. 25 Mar 2016In : Journal of Biological Chemistry.291, 13, p. 7045-705915 p.

Research output: Contribution to journal › Article

Redox Signaling In The Cardiomyocyte: From Physiology To Failure

Santos, C. XC., Raza, S., Shah, A. M. & [Unknown], FM. 14 Mar 2016In : International Journal of Biochemistry and Cell Biology.

Research output: Contribution to journal › Article

Mutual regulation of epicardial adipose tissue and myocardial redox state by PPAR-γ/adiponectin signalling

Antonopoulos, A. S., Margaritis, M., Verheule, S., Recalde, A., Sanna, F., Herdman, L., Psarros, C., Nasrallah, H., Coutinho, P., Akoumianakis, I., Brewer, A. C., Sayeed, R., Krasopoulos, G., Petrou, M., Tarun, A., Tousoulis, D., Shah, A. M., Casadei, B., Channon, K. M. & Antoniades, C. 4 Mar 2016In : Circulation Research.118, 5, p. 842-85514 p.

Research output: Contribution to journal › Article

Ambulatory heart rate range predicts mode-specific mortality and hospitalisation in chronic heart failure

Cubbon, R. M., Ruff, N., Groves, D., Eleuteri, A., Denby, C., Kearney, L., Ali, N., Walker, A. M. N., Jamil, H., Gierula, J., Gale, C. P., Batin, P. D., Nolan, J., Shah, A. M., Fox, K. A. A., Sapsford, R. J., Witte, K. K. & Kearney, M. T. 1 Feb 2016In : Heart.102, 3, p. 223-2297 p.

Research output: Contribution to journal › Article

NOX4-driven ROS formation mediates PTP inactivation and cell transformation in FLT3ITD-positive AML cells

Jayavelu, A. K. , Müller, J. P. , Bauer, R. , Böhmer, S. A. , Lässig, J. , Cerny-Reiterer, S. , Sperr, W. R. , Valent, P. , Maurer, B. , Moriggl, R. , Schröder, K. , Shah, A. M. , Fischer, M. , Scholl, S. , Barth, J. , Oellerich, T. , Berg, T. , Serve, H. , Frey, S. , Fischer, T. & 2 othersHeidel, F. H. & Böhmer, F. D.1 Feb 2016In : Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K.30, 2, p. 473-48311 p.

Research output: Contribution to journal › Article

Transcriptional regulation of cystathionine-γ-lyase in endothelial cells by NADPH oxidase 4-dependent signaling

Mistry, R. K., Murray, T. V. A., Prysyazhna, O., Martin, D., Burgoyne, J., Santos, C., Eaton, P., Shah, A. M.Brewer, A. C.22 Jan 2016In : Journal of Biological Chemistry.291, 4, p. 1774-178815 p.

Research output: Contribution to journal › Article

Targeted redox inhibition of protein phosphatase 1 by Nox4 regulates eIF2α-mediated stress signaling

Santos, C. X. , Hafstad, A. D. , Beretta, M. , Zhang, M. , Molenaar, C. , Kopec, J. , Fotinou, D. , Murray, T. V. , Cobb, A. M. , Martin, D. , Zeh Silva, M. , Anilkumar, N. , Schröder, K. , Shanahan, C. M. , Brewer, A. C. , Brandes, R. P. , Blanc, E. , Parsons, M. , Belousov, V. , Cammack, R.& 3 othersHider, R. C., Steiner, R. A.Shah, A. M.18 Jan 2016In : The EMBO journal.35, 2, p. 115-236

Research output: Contribution to journal › Article

Bone marrow transplantation modulates tissue macrophage phenotype and enhances cardiac recovery after subsequent acute myocardial infarction

Protti, A., Mongue-Din, H., Mylonas, K. J., Sirker, A., Sag, C. M., Swim, M. M., Maier, L., Sawyer, G., Dong, X., Botnar, R., Salisbury, J., Gray, G. A. & Shah, A. M.Jan 2016In : Journal of Molecular and Cellular Cardiology.90, p. 120-1289 p.

Research output: Contribution to journal › Article

Triple-Modal Imaging of Magnetically-Targeted Nanocapsules in Solid Tumours In Vivo

Bai, J., Wang, J. T-W., Rubio, N., Protti, A., Heidari, H., Elgogary, R., Southern, P., Al-Jamal, W. T., Sosabowski, J., Shah, A. M., Bals, S., Pankhurst, Q. A. & Al-Jamal, K. T.Jan 2016In : Theranostics.6, 3, p. 342-5615 p.

Research output: Contribution to journal › Article

The NADPH oxidase Nox4 has anti-atherosclerotic functions

Schürmann, C., Rezende, F., Kruse, C., Yasar, Y., Löwe, O., Fork, C., Van De Sluis, B., Bremer, R., Weissmann, N., Shah, A. M., Jo, H., Brandes, R. P. & Schröder, K. 21 Dec 2015In : European Heart Journal.36, 48, p. 3447-345610 p.

Research output: Contribution to journal › Article

NADPH oxidase 4 regulates homocysteine metabolism and protects against acetaminophen-induced liver damage in mice

Murray, T. V. A., Dong, X., Sawyer, G. J., Caldwell, A., Halket, J., Sherwood, R., Quaglia, A., Dew, T., Anilkumar, N., Burr, S., Mistry, R. K., Martin, D., Schröder, K., Brandes, R. P., Hughes, R. D., Shah, A. M.Brewer, A. C.1 Dec 2015In : Free Radical Biology and Medicine.89, p. 918-93013 p.

Research output: Contribution to journal › Article

Assessment of Myocardial Remodeling Using an Elastin/Tropoelastin Specific Agent with High Field Magnetic Resonance Imaging (MRI)

Protti, A., Lavin , B., Dong, X., Lorrio, S., Robinson, S., Onthank, D., Shah, A. M.Botnar, R. M.13 Aug 2015In : Journal of the American Heart Association.4, 8, 12 p., e001851

Research output: Contribution to journal › Article

Pulmonary haemodynamics in sickle cell disease are driven predominantly by a high-output state rather than elevated pulmonary vascular resistance: A prospective 3-dimensional echocardiography/Doppler study

Mushemi-Blake, S., Melikian, N., Drasar, E., Bhan, A., Lunt, A., Desai, S. R., Greenough, A., Monaghan, M. J., Thein, S. L. & Shah, A. M.13 Aug 2015In : PL o S One .10, 8, e0135472

Research output: Contribution to journal › Article

Deficient angiogenesis in redox-dead Cys17Ser PKARIα knock-in mice

Burgoyne, J., Rudyk, O., Cho, H. J., Prysyazhna, O., Hathaway, N., Weeks, A., Evans, R., Ng, T., Schröder, K., Brandes, R. P., Shah, A. M.Eaton, P.10 Aug 2015In : Nature Communications.6, 7920

Research output: Contribution to journal › Article

Contractile Function during Angiotensin-II Activation: Increased Nox2 Activity Modulates Cardiac Calcium Handling via Phospholamban Phosphorylation

Zhang, M., Prosser, B. L., Bamboye, M. A., Gondim, A. N. S., Santos, C. X., Martin, D., Ghigo, A., Perino, A., Brewer, A. C., Ward, C. W., Hirsch, E., Lederer, W. J. & Shah, A. M.21 Jul 2015In : Journal of the American College of Cardiology.66, 3, p. 261-27212 p.

Research output: Contribution to journal › Article

Bcl-2-like protein 13 is a mammalian Atg32 homologue that mediates mitophagy and mitochondrial fragmentation

Murakawa, T., Yamaguchi, O., Hashimoto, A., Hikoso, S., Takeda, T., Oka, T., Yasui, H., Ueda, H., Akazawa, Y., Nakayama, H., Taneike, M., Misaka, T., Omiya, S., Shah, A. M., Yamamoto, A., Nishida, K., Ohsumi, Y., Okamoto, K., Sakata, Y. & Otsu, K.6 Jul 2015In : Nature communications.6, p. 75271 p.

Research output: Contribution to journal › Article

Age-associated pro-inflammatory remodeling and functional phenotype in the heart and large arteries

Wang, M. & Shah, A. M.1 Jun 2015In : Journal of Molecular and Cellular Cardiology.83, p. 101-11111 p.

Research output: Contribution to journal › Article

Impaired Neuronal Nitric Oxide Synthase-Mediated Vasodilator Responses to Mental Stress in Essential Hypertension

Khan, S. G., Geer, A., Fok, H. W., Shabeeh, H., Brett, S. E., Shah, A. M.Chowienczyk, P. J.Apr 2015In : Hypertension.65, 4, p. 903-9097 p.

Research output: Contribution to journal › Article

Nicotinamide adenine dinucleotide phosphate oxidase-4-dependent upregulation of nuclear factor erythroid-derived 2-like 2 protects the heart during chronic pressure overload

Smyrnias, I., Zhang, X., Zhang, M., Murray, T. V. A., Brandes, R. P., Schröder, K., Brewer, A. C.Shah, A. M.4 Mar 2015In : Hypertension.65, 3, p. 547-5537 p.

Research output: Contribution to journal › Article

Cardiac-targeted NADPH oxidase 4 in the adaptive cardiac remodelling of the murine heart

Nabeebaccus, A., Hafstad, A., Eykyn, T., Yin, X., Brewer, A., Zhang, M., Mayr, M.Shah, A.26 Feb 2015In : Lancet.385 Suppl 1, p. S73

Research output: Contribution to journal › Article

Redox regulation of cardiomyocyte cell cycling via an ERK1/2 and c-Myc-dependent activation of cyclin D2 transcription

Murray, T. V. A., Smyrnias, I., Schnelle, M., Mistry, R. K., Zhang, M., Beretta, M., Martin, D., Anilkumar, N., de Silva, S. M., Shah, A. M.Brewer, A. C.1 Feb 2015In : Journal of Molecular and Cellular Cardiology.79, p. 54-6815 p.

Research output: Contribution to journal › Article

Serial soluble ST2 for the monitoring of pharmacologically optimised chronic stable heart failure

Piper, S. E., Sherwood, R., Amin-Youssef, G. F., Shah, A. M.McDonagh, T. A.15 Jan 2015In : International Journal of Cardiology.178, p. 284-2918 p.

Research output: Contribution to journal › Article

Heart failure: Mitochondrial dysfunction and oxidative stress in CHF

Okonko, D. O.Shah, A. M.11 Jan 2015In : Nature Reviews Cardiology.12, 1, p. 6-83 p.

Research output: Contribution to journal › Article

Parsing the role of NADPH oxidase enzymes and reactive oxygen species in heart failure

Shah, A. M.2015In : Circulation (Baltimore).131, 7, p. 602-6043 p.

Research output: Contribution to journal › Article

Menthol inhibits detrusor contractility independently of TRPM8 Activation

Ramos-Filho, A. C. S., Shah, A., Augusto, T. M., Barbosa, G. O., Leiria, L. O., De Carvalho, H. F., Antunes, E. & Grant, A. D.6 Nov 2014In : PL o S One .9, 11, e111616

Research output: Contribution to journal › Article

NADPH oxidase 2 mediates angiotensin II-dependent cellular arrhythmias via PKA and CaMKII

Wagner, S., Dantz, C., Flebbe, H., Azizian, A., Sag, C. M., Engels, S., Möllencamp, J., Dybkova, N., Islam, T., Shah, A. M. & Maier, L. S. 1 Oct 2014In : Journal of Molecular and Cellular Cardiology.75, p. 206-21510 p.

Research output: Contribution to journal › Article

Redox State of Pentraxin 3 as a Novel Biomarker for Resolution of Inflammation and Survival in Sepsis

Cuello, F., Shankar-Hari, M., Mayr, U., Yin, X., Marshall, M., Suna, G., Willeit, P., Langley, S. R., Jayawardhana, T., Zeller, T., Terblanche, M., Shah, A. M.Mayr, M.1 Oct 2014In : MOLECULAR AND CELLULAR PROTEOMICS.13, 10, p. 2545-255713 p.

Research output: Contribution to journal › Article

Preface for redox signalling in the cardiovascular system

Eaton, P.Shah, A. M.Aug 2014In : Journal of Molecular and Cellular Cardiology.73, p. 1-11 p.

Research output: Contribution to journal › Editorial

Redox regulation of cardiac hypertrophy

Sag, C. M., Santos, C. X. C. & Shah, A. M.Aug 2014In : Journal of Molecular and Cellular Cardiology.73, p. 103-1119 p.

Research output: Contribution to journal › Literature review

The imbalanced redox status in senescent endothelial cells is due to dysregulated Thioredoxin-1 and NADPH oxidase 4

Goy, C., Czypiorski, P., Altschmied, J., Jakob, S., Rabanter, L. L., Brewer, A. C., Ale-Agha, N., Dyballa-Rukes, N., Shah, A. M. & Haendeler, J. Aug 2014In : Experimental Gerontology.56, p. 45-528 p.

Research output: Contribution to journal › Article

Endothelial NADPH oxidase-2 promotes interstitial cardiac fibrosis and diastolic dysfunction through pro-inflammatory effects and endothelial-mesenchymal transition

Murdoch, C., Chaubey, S., Zeng, L., Yu, B., Ivetic, A., Walker, S. J., Vanhoutte, D., Heymans, S., Grieve, D. J., Cave, A. C., Brewer, A. C., Zhang, M., Shah, A. M.Ivetic, A.24 Jun 2014In : Journal of the American College of Cardiology.63, 24, p. 2734-27418 p.

Research output: Contribution to journal › Article

High Frequency Speckle Tracking Echocardiography in the Assessment of Left Ventricular Function after Murine Myocardial Infarction

Bhan, A., Sirker, A., Zhang, J., Protti, A., Catibog, N., Driver, W., Botnar, R., Monaghan, M.Shah, A. M.1 May 2014In : AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY.306, 9, p. H1371-H138313 p.