Anna C. Nelson Dittrich

Department of Biochemistry and BiophysicsPhone: (979) 845-2600

Texas A&M UniversityEmail:

College Station, TX 77843

EDUCATION

Texas A&M University, College Station, TX2006 –2012

Ph.D. Biochemistry

GPA: 3.90/4.00

Southwestern Oklahoma State University, Weatherford, OK2002 – 2006

B.S. Biology (minor chemistry)

GPA: 3.92/4.00

RESEARCH INTERESTS

Protein phosphorylation and signal transduction pathways, cell death regulation, comparative andevolutionary biology, evolution of conserved pathways, plant-pathogen and plant-insect interactions, evolution of herbivory and host specificity, natural variation in host-parasite interactions.

RESEARCH POSITIONS

University of Arizona–Department of Ecology and Evolutionary Biology2012 – Present

Postdoctoral researcher (PI: Noah Whiteman)

Main project: Evolutionary biochemistry of mustard oil detoxification in the Drosophilidae

Other projects: Thermal ecology of plant-herbivore interactions

Texas A&M University–Department of Biochemistry and Biophysics2006 – 2012

Ph.D. student(PI: Timothy Devarenne)

Dissertation project: Investigation of a 3-phosphoinositide-dependent protein kinase-1 (PDK1) homologue in the moss Physcomitrella patens.

Other projects: Characterization of a second PDK1 phosphorylation site in the cell-death suppressing protein kinase Adi3, identification of an Adi3 mutant that can specifically utilize bulky ATP analogues.

Southwestern Oklahoma State University–Department of Chemistry and Physics2005 – 2006

Undergraduate research assistant (PIs: William Kelly and Doris Benbrook)

Project: Characterization of the apopotosis-inducing effects of SHet-A2, a heteroarotinoid anticancer drug, on mitochondria isolated from cancer cell lines.

Southwestern Oklahoma State University–Department of Biological Sciences2004 – 2006

Undergraduate research assistant (PI: MuatasemUbeidat)

Project: Investigation of 5’-nucleotidase localization and activity in Dictyosteliumdiscoideum.

Southwestern Oklahoma State University–Department of Biological Sciences2004 – 2006

Undergraduate research assistant (PI: Peter Grant)

Project: Collection and cataloging of mayfly species in all major waterways throughout Oklahoma.

MENTORING

Devarenne lab – Texas A&M University2010 – 2012

Mentor to undergraduate research assistant

Three semesters mentoring an undergraduate researcher, Austin Rivera

Project: Interaction between 3-phosphoinositide-dependent protein kinase-1 (PDK1) and the receptor-like kinase BAK1 in Arabidopsis.

Biochemistry Graduate Student Association – Texas A&M University2007 – 2012

Active member and mentor to new graduate students

Provide advice and assistance to one incoming biochemistry graduate student each year

Participate in recruitment of new biochemistry graduate students each spring

Assist first-year biochemistry graduate studentswith development of an original research proposal (ORP) that is presented at the end of their first year

Ubeidat lab–Southwestern Oklahoma State University2005 – 2006

Mentor to undergraduate research assistants

Provide advice and assistance to several new undergraduate researchers

Project: Investigation of 5’-nucleotidase localization and activity in Dictyosteliumdiscoideum.

TEACHING EXPERIENCE

Department of Biochemistry and Biophysics– Texas A&M University2011

Teaching Assistant for Donald Pettigrew–BICH 410 (Comprehensive biochemistry I) lecture

Department of Biochemistry and Biophysics– Texas A&M University2010

Teaching Assistant for Bryant Miles–BICH 411 (Comprehensive biochemistry II) lecture

Department of Biochemistry and Biophysics– Texas A&M University2009

Teaching Assistant for Bill Park –BICH 411 (Comprehensive biochemistry II) lecture

Department of Biochemistry and Biophysics– Texas A&M University2008

Teaching Assistant for Leisha Mullins–BICH 411 (Comprehensive biochemistry II) lecture

Department of Biological Sciences– Southwestern Oklahoma State University 2005

Teaching Assistant for MuatasemUbeidat–BIOL 3254 (Genetics) laboratory

Department of Biological Sciences– Southwestern Oklahoma State University 2004 – 2005

Biology departmental tutor–BIOL 1004 (Biological Concepts), BIOL 1054 (Principles of Biology), BIOL 2204 (Introductory Zoology), BIOL 2404 (Introductory Botany), BIOL 3254 (Genetics), BIOL 3704 (Human Anatomy)

AWARDS

2012: Postdoctoral Excellence in Research and Teaching (PERT) fellowship, University of Arizona Center for Insect Science

2012:John Mack Prescott graduate research and academicexcellence award ($1000), Texas A&M Department of Biochemistry and Biophysics

2011:Travel grant award ($575), American Society of Plant Biologists

2011: Travel grant award ($600), Texas A&M Department of Biochemistry and Biophysics

2010: Teaching excellenceaward for 2009, Texas A&M Department of Biochemistry and Biophysics

2008: Third place, Biochemistry and Biophysics departmentalresearch competition ($200)

2006: Molecular and Cellular Biology training program, Texas A&M Department of Biochemistry and Biophysics

2006: Graduate merit fellowship, Texas A&M University

2006: Hobart F. Landreth award for outstanding research, Southwestern Oklahoma State University

2006: INBRE summer research grant ($3000), Southwestern Oklahoma State University

2005: M.D. Jirous Foundation scholarship, Southwestern Oklahoma State University

2005: Otis King memorial scholarship, Southwestern Oklahoma State University

2005: Mary L. Miller field biology award, Southwestern Oklahoma State University

ORGANIZATIONS AND ACTIVITIES

Texas A&M Student Research Week judge2012

American Society of Plant Biologists member2011 – present

QPR Suicide Prevention, certified gatekeeper2011 – present

Reviewed manuscripts: FEBS Lett, J Biol Chem, PlantPhysiolBiochem2010-2012

Laboratory Management and Conflict Resolution workshop participant, Texas A&M University2010

Biochemistry Original Research Proposal volunteer, Texas A&M University2007 – 2012

Biochemistry graduate student recruiting volunteer, Texas A&M University2007 – 2012

Biochemistry Graduate Association member, Texas A&M University2006 – 2012

Molecular and Cellular Biology training program, Texas A&M University2006 – 2007

National Honor Society member2005 – 2006

Weatherford blood testing clinic volunteer, Southwestern Oklahoma State University2004 – 2006

Biology Club member, Southwestern Oklahoma State University2003 – 2006

PUBLICATIONS

Nelson Dittrich AC, Devarenne TP (2012) Perspectives in PDK1 evolution: insights from photosynthetic and non-photosynthetic organisms. Plant Signaling and Behavior in press, publication June 2012.

Nelson Dittrich AC, Devarenne TP (2012) Characterization of a PDK1 homologue from the moss Physcomitrella patens.Plant Physiology158: 1018-1033.

Nelson Dittrich AC, Devarenne TP (2012) An ATP analog-sensitive version of the tomato cell death suppressor protein kinase Adi3 for use in substrate identification. BiochimicaetBiophysicaActa Proteins and Proteomics 1824: 269-273.

Le TC, Berlin KD, Benson SD, Eastman MA, Bell-Eunice G, Nelson AC, and Benbrook DM (2007) Heteroarotinoids with anti-cancer activity against ovarian cancer cells.Open Medicinal Chemistry Journal 1: 11-23.

MANUSCRIPTS IN PREPARATION

Nelson Dittrich AC, Devarenne TP. Significance of a second major phosphorylation site on the tomato cell death suppressing protein kinase Adi3.

Nelson A, Cifuentes-Rojas C, Shakirov EV, Nelson Dittrich AC, Shippen DE.AtPOT1b: a telomerase accessory factor important for the processing of TER2 in Arabidopsis thaliana.

Nelson A, Renfrew K, Nelson Dittrich AC, Surovtseva Y, Shippen DE.POT1c: a novel component of the telomerecapping complexand negative regulator of telomerase activityin Arabidopsis thaliana.

PRESENTATIONS

2012: “Regulation of plant cell death by conserved protein kinases.” Invited talk, SWOSU Biology departmental seminar series. February 2012, Southwestern Oklahoma State University (Weatherford, OK).

2011: “3-phosphoinositide dependent protein kinase-1 in the mossPhyscomitrella patens.” August 2011, American Society of Plant Biologists annual meeting (Minneapolis, MN).

2008: “Activation of the protein kinase Adi3, a negative regulator of cell death in tomato, by the upstream kinase PDK1.” Biochemistrystudent research competition.February 2008, Texas A&M University (College Station, TX).

2006: “Mitochondrial effects of the anticancer compound SHetA2 on ovarian cancer.” INBRE summer research seminar.July 2006, University of Oklahoma Health Sciences Center (Oklahoma City, OK).

2006: “Importance of Dictyosteliumdiscoideum 5’ nucleotidase.” Oklahoma Research Day for Regional Universities.Spring 2006, Oklahoma State Capitol Building (Oklahoma City, OK).

2005: “Dictyosteliumdiscoideum 5’ nucleotidase activity and localization.” SWOSU Research Day.Spring 2005, Southwestern Oklahoma State University (Weatherford, OK).

REFERENCES

Noah Whiteman, University of Arizona

Department of Ecology and Evolutionary Biology

1041 E. Lowell St., P.O. Box 210088

Tucson, AZ 84721

Phone: (520) 626-3950

E-mail:

Timothy Devarenne, Texas A&M University

Department of Biochemistry and Biophysics

300 Olsen Blvd.

College Station, TX 77840

Phone: (979) 862-6509

E-mail:

Bill Park, Texas A&M University

Department of Biochemistry and Biophysics

300 Olsen Blvd.

College Station, TX 77840

Phone: (979) 845-8868

E-mail:

Michael Polymenis, Texas A&M University

Department of Biochemistry and Biophysics

300 Olsen Blvd.

College Station, TX 77840

Phone: (979) 458-3259

E-mail:

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