Table S6.Components of Intracellular Signaling Pathways Involved in Immune Responses Predicted

Table S6.Components of Intracellular Signaling Pathways Involved in Immune Responses Predicted

Table S6.Components of intracellular signaling pathways involved in immune responses predicted from the P. strigosatranscriptome.

Signaling Pathway / Component / Predicted Domains (InterProScan)a / Transcript ID
Apoptosis / FasL / TNF / dist251225_c1_seq1
Fas / TNFR+DED / dist233052_c0_seq1
FADD-like / DED / dist97950_c0_seq1
Caspase 3-like / CASc / dist244920_c1_seq1
Caspase 8 / DED+DED+CASc / dist252854_c0_seq1
Caspase 9 / CARD+CASc / dist251986_c0_seq2
Bcl2-like / Bcl-2 / dist152189_c0_seq1
API5 / API5 / dist159764_c0_seq1
AIF2 / Pyr_Redox / dist253149_c0_seq1
TGF-beta / TGFB-like / TGF_beta,TGFb_propeptide / dist238328_c1_seq1
TGFBR1-like / TGFbeta_recp+TM+TGFbeta_GS+Pkinase / dist245909_c0_seq1
SARA-like / FYVE / dist304490_c0_seq1
SMAD2/3 / MH1+MH2 / dist250909_c2_seq1
SMAD4 / MH1(2) / dist246521_c4_seq1
TLR / MyD88 / Death+TIR / dist250879_c2_seq1
TRAF-like / Zf_TRAF(2)+MATH / dist246849_c5_seq1
TAB / PP2C / dist206647_c0_seq1
TAK1 / Pkinase / dist251115_c6_seq1
TRAM / TRAM1+TRAM_LAG1_CLN8 / dist242701_c1_seq1
TRAF3-like / RING+DM+zf-TRAF+End3+MATH / dist253127_c0_seq1
TBK1-like / PKc-like+UBL-TBK1 / dist249257_c5_seq1
IRF3 / IRF+IRF3 / dist97916_c0_seq1
IkBKinase / Pkinase / dist244412_c7_seq1
NFkB Inhibitor / Ank(3) / dist226100_c1_seq2
NFkB partial / RHD / dist243377_c6_seq1
Ank(5) / dist252982_c0_seq18
AnK(3)+Death / dist243377_c5_seq1
Wnt / Frizzled / 7tm / dist247246_c1_seq1
GSK-3B-like / Pkinase / dist237729_c0_seq1
Beta-catenin / ARM(5) / dist252284_c2_seq2
TCF-like / HMG-box / dist148750_c0_seq1
Notch / NOTCH-like / LNR+NOD+NODP+TM / dist222573_c1_seq1
EGF(2)+LNR(2) / dist222573_c4_seq1
EGF+LNR(3) / dist187720_c4_seq1
EGF(15) / dist249172_c0_seq1
Delta-like / DSL+EGF(20)+TM / dist250784_c1_seq1
TACE-like / Pep_M12B+Reprolysin+Disintegrin+Adam_CR / dist247195_c1_seq2
NUMB-like / PID / dist252640_c1_seq1
Deltex-like / Zf-RING+WWE / dist230122_c3_seq1
Suppressor of Hairless / Lag1_DNAbind+BTD+TIG / dist246926_c0_seq3
MAPK / FGF / FGF / dist251193_c0_seq3
FGFR-like / Ig+Pkinase_tyr / dist251021_c4_seq2
GRB2-like / SH2+SH3 / dist222508_c1_seq1
SOS-like / PH(2)+PDZ+RhoGEF+PH / dist252625_c0_seq9
Ras-like / RAS / dist234557_c1_seq1
MAPK-like / Pkinase / dist249945_c0_seq14
MNK-like / Pkinase / dist249376_c7_seq1
RSK-like / Pkinase(2) / dist252761_c2_seq3
CREB / pKID+bZIP_1 / dist252784_c1_seq12
MYC-like / HLH+Myc_N / dist217462_c1_seq1
Hedgehog / Hedgehog / HH_Signal+Hint / dist240860_c2_seq1
Patched / Patched / dist228738_c5_seq1
SMO-like / 7tm / dist221208_c0_seq1
Ci/Gli / zf-H2C2_2(2) / dist228856_c2_seq1
PI3K-Akt-mTOR / PI3K / PI3K_p85B+PI3K_rbd+PI3K_C2 / dist233999_c0_seq1
Akt/PKB / PH+Pkinase+Pkinase_C / dist249274_c0_seq1
Jak-Stat / Stat / STAT_alpha+STAT_bind+SH2 / dist241535_c1_seq1

aProtein domains predicted with InterProScan. SP, signal peptide; TM, transmembrane region; TNRF, tumor necrosis factor receptor; DED, death effector domain; CASc, caspase; CARD, caspase recruitment domain; Bcl-2; B-cell lymphoma-2; API5, apoptosis inhibitory protein 5; Pyr_Redox, Pyridine nucleotide-disulphide oxidoreductase; TGF, transforming growth factor; Pkinase, protein kinase; FYVE, Fab1/YOTB/Vac1/EEA1; MH, MAD homology; MATH, meprin and TRAF homology; TRAF, TNF receptor associated factor; PP2C, protein phosphatase 2C; TRAM, TRM2 and miaB; DM, Doublesex DNA-binding motif; IRF, interferon regulatory factor; ANK, ankyrin; RDH, Rel homology domain; 7tm, 7 transmembrane domains; ARM, Armadillo/beta-catenin-like repeats; HMG, high mobility group; LNR, Lin-12/Notch repeat; NOD, NOTCH domain; EGF, epidermal growth factor; DSL, Delta/Serrate ligand; PID, Phosphotyrosine interaction domain; WWE, Domain in Deltex and TRIP12 homologues; BTD, Beta trefoil DNA binding domain; TIG, Ig-like, plexins, transcription factors; FGF, fibroblast growth factor; Ig, immunoglobulin; SH, Src homology; PH, Pleckstrin homology; PDZ, PSD-95/Dlg/ZO; RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; pKID, phosphorylatedkinase-inducible-domain; bZIP, basic-leucine zipper; HLH, helix loop helix; HH, hedgehog; Hint, Hedgehog/Intein; zf-H2C2, His(2)-Cys(2) zinc finger; PI3K_p85B, PI3-kinase family, p85-binding domain; PI3K_rbd, PI3-kinase family, Ras-binding domain; Pi3K_C2, Phosphoinositide 3-kinase with C2 domain; STAT, signal transducers and activators of transcription. Plus symbols (+) separate different domains within a protein. The number of repetitions of a given domainin parenthesis.