Supplemenatry Table 4:List of Genes Differentially Expressed in NNK + LPS-Induced Mouse

Supplemenatry Table 4:List of Genes Differentially Expressed in NNK + LPS-Induced Mouse

Supplemenatry Table 4:List of genes differentially expressed in NNK + LPS-induced mouse lung tumors versus normal lung from vehicle-treated mice

NNK+LPS vs Con
Gene / Description / FC / FDR / Cellular Location / Type(s)
1100001G20Rik / 2.1 / 4.8E-03
1110002E22Rik / RIKEN cDNA 1110002E22 gene / -3.9 / 4.0E-02 / Other / other
1300002K09Rik / 5.2 / 1.3E-07
1700084C01Rik / chromosome 1 open reading frame 110 / -2.0 / 7.3E-04 / Other / other
1700084C06Rik / RIKEN cDNA 1700084C06 gene / 3.6 / 3.0E-02 / Other / other
2010007H06Rik / RIKEN cDNA 2010007H06 gene / -2.0 / 3.0E-02 / Other / other
2310014L17Rik / uncharacterized LOC646862 / 2.7 / 3.2E-03 / Other / other
2310015B20Rik / RIKEN cDNA 2310015B20 gene / -5.3 / 2.0E-02 / Other / other
2310050B05Rik / -23.3 / 2.2E-05
2610203C22Rik / RIKEN cDNA 2610203C22 gene / -2.0 / 1.0E-02 / Other / other
2610305D13Rik / zinc finger protein 616 / -2.0 / 1.9E-03 / Nucleus / other
3010001F23Rik / RIKEN cDNA 3010001F23 gene / -38.1 / 1.0E-02 / Other / other
3010026O09Rik / chromosome 5 open reading frame 45 / -2.3 / 2.0E-02 / Other / other
4732491K20Rik / RIKEN cDNA 4732491K20 gene / -2.6 / 4.0E-02 / Other / other
4930429F24Rik / RIKEN cDNA 4930429F24 gene / 2.4 / 6.1E-04 / Other / other
4930430E12Rik / RIKEN cDNA 4930430E12 gene / 5.4 / 5.6E-04 / Other / other
5430421N21Rik / keratin 83 / 12.1 / 8.0E-04 / Cytoplasm / other
5830411N06Rik / RIKEN cDNA 5830411N06 gene / 25.6 / 2.2E-05 / Plasma Membrane / other
6030408B16Rik / RIKEN cDNA 6030408B16 gene / -2.3 / 5.8E-03 / Other / other
6330416G13Rik / chromosome 9 open reading frame 91 / 2.1 / 4.3E-07 / Cytoplasm / other
6330418K02Rik / RIKEN cDNA 6330418K02 gene / -2.4 / 2.0E-02 / Other / other
6430573F11Rik / KIAA1456 / -2.1 / 3.0E-02 / Other / other
9230104L09Rik / RIKEN cDNA 9230104L09 gene / -2.7 / 4.1E-03 / Other / other
9330175E14Rik / RIKEN cDNA 9330175E14 gene / 2.9 / 1.5E-03 / Other / other
9330182L06Rik / KIAA1324-like / 2.0 / 1.0E-04 / Other / other
9530077C05Rik / KIAA0895 / 2.8 / 1.0E-02 / Other / other
A2m / alpha-2-macroglobulin / 24.7 / 8.8E-03 / Extracellular Space / transporter
A530020G20Rik / RIKEN cDNA A530020G20 gene / 2.1 / 1.8E-04 / Other / other
A530032D15Rik / RIKEN cDNA C130026I21 gene / 3.9 / 2.0E-02 / Other / other
A830018L16Rik_1 / -2.2 / 4.0E-02
A830036E02Rik / 3.1 / 1.0E-02
A930001C03Rik / RIKEN cDNA A930001C03 gene / 3.2 / 3.3E-04 / Other / other
AA467197 / chromosome 15 open reading frame 48 / 8.2 / 1.9E-05 / Nucleus / other
Aard / alanine and arginine rich domain containing protein / -2.5 / 1.0E-02 / Other / other
Aass / aminoadipate-semialdehyde synthase / 2.9 / 1.4E-05 / Cytoplasm / enzyme
Abca8a / ATP-binding cassette, sub-family A (ABC1), member 8a / -2.1 / 5.3E-06 / Other / transporter
Abi3bp / ABI gene family, member 3 (NESH) binding protein / -2.1 / 3.1E-08 / Extracellular Space / other
Ablim3 / actin binding LIM protein family, member 3 / -2.0 / 1.4E-03 / Cytoplasm / other
Abra / actin-binding Rho activating protein / -4.5 / 1.9E-03 / Cytoplasm / transcription regulator
AC120404.1 / 60.0 / 1.5E-07
Acaa1b / acetyl-Coenzyme A acyltransferase 1B / -2.2 / 9.3E-06 / Other / enzyme
Ackr4_2 / -3.8 / 2.0E-02
Acp5 / acid phosphatase 5, tartrate resistant / 2.9 / 6.2E-12 / Cytoplasm / phosphatase
Acsbg1 / acyl-CoA synthetase bubblegum family member 1 / 3.2 / 5.6E-03 / Cytoplasm / enzyme
Acsm1 / acyl-CoA synthetase medium-chain family member 1 / -2.9 / 3.0E-05 / Cytoplasm / enzyme
Acta1 / actin, alpha 1, skeletal muscle / -4.6 / 3.0E-02 / Cytoplasm / other
Actc1 / actin, alpha, cardiac muscle 1 / -4.7 / 9.5E-07 / Cytoplasm / enzyme
Actn2 / actinin, alpha 2 / -6.2 / 2.1E-03 / Nucleus / transcription regulator
Acvr1c / activin A receptor, type IC / -5.3 / 3.0E-02 / Plasma Membrane / kinase
Adam19 / ADAM metallopeptidase domain 19 / 2.2 / 4.7E-10 / Plasma Membrane / peptidase
Adamts17 / ADAM metallopeptidase with thrombospondin type 1 motif, 17 / -3.4 / 1.3E-06 / Extracellular Space / other
Adamts19 / ADAM metallopeptidase with thrombospondin type 1 motif, 19 / -3.6 / 5.6E-03 / Extracellular Space / peptidase
Adamts4 / ADAM metallopeptidase with thrombospondin type 1 motif, 4 / 5.2 / 1.3E-03 / Extracellular Space / peptidase
Adamts8 / ADAM metallopeptidase with thrombospondin type 1 motif, 8 / -2.3 / 4.9E-05 / Extracellular Space / peptidase
Add2 / adducin 2 (beta) / -3.1 / 3.0E-02 / Cytoplasm / other
Adm2 / adrenomedullin 2 / 12.0 / 3.2E-04 / Extracellular Space / other
Adra1a / adrenoceptor alpha 1A / -3.4 / 7.5E-05 / Plasma Membrane / G-protein coupled receptor
Adra1b / adrenoceptor alpha 1B / -4.6 / 6.0E-05 / Plasma Membrane / G-protein coupled receptor
Adrb3 / adrenoceptor beta 3 / -2.6 / 2.4E-03 / Plasma Membrane / G-protein coupled receptor
Agap2 / ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 / 2.1 / 4.2E-03 / Nucleus / enzyme
Agt / angiotensinogen (serpin peptidase inhibitor, clade A, member 8) / -7.1 / 1.1E-05 / Extracellular Space / growth factor
AI836003 / -2.6 / 4.0E-02
Aif1 / allograft inflammatory factor 1 / 2.3 / 3.0E-02 / Nucleus / other
Aif1l / allograft inflammatory factor 1-like / 2.1 / 1.0E-02 / Plasma Membrane / other
Ak4 / adenylate kinase 4 / 4.2 / 3.3E-03 / Cytoplasm / kinase
Akap12 / A kinase (PRKA) anchor protein 12 / -2.4 / 5.2E-05 / Cytoplasm / transporter
Akap6 / A kinase (PRKA) anchor protein 6 / -3.1 / 3.3E-04 / Nucleus / other
Alb / albumin / 3.9 / 3.2E-03 / Extracellular Space / transporter
Aldh1l2 / aldehyde dehydrogenase 1 family, member L2 / 4.6 / 5.5E-07 / Cytoplasm / enzyme
Aldh3b2 / aldehyde dehydrogenase 3 family, member B2 / -3.8 / 4.0E-02 / Other / other
Amot / angiomotin / -2.0 / 1.0E-02 / Plasma Membrane / other
Amph / amphiphysin / -2.7 / 3.4E-07 / Plasma Membrane / other
Angpt1 / angiopoietin 1 / -2.4 / 1.3E-07 / Extracellular Space / growth factor
Angpt2 / angiopoietin 2 / -2.2 / 6.2E-03 / Extracellular Space / growth factor
Angpt4 / angiopoietin 4 / -2.8 / 8.3E-03 / Extracellular Space / growth factor
Ank1 / ankyrin 1, erythrocytic / -2.2 / 3.9E-03 / Plasma Membrane / other
Ankrd1 / ankyrin repeat domain 1 (cardiac muscle) / -2.8 / 5.4E-04 / Cytoplasm / transcription regulator
Ankrd22 / ankyrin repeat domain 22 / 7.9 / 5.1E-05 / Nucleus / transcription regulator
Ankrd34b / ankyrin repeat domain 34B / 12.7 / 1.1E-07 / Nucleus / transcription regulator
Ankrd37 / ankyrin repeat domain 37 / 3.8 / 2.6E-04 / Other / other
Ankrd65 / ankyrin repeat domain 65 / -2.1 / 9.7E-03 / Other / other
Ano4 / anoctamin 4 / -41.2 / 8.1E-03 / Plasma Membrane / ion channel
Aoah / acyloxyacyl hydrolase (neutrophil) / 4.2 / 1.1E-03 / Extracellular Space / enzyme
Apba2 / amyloid beta (A4) precursor protein-binding, family A, member 2 / 3.4 / 2.0E-02 / Cytoplasm / transporter
Apln / apelin / -2.7 / 9.0E-04 / Extracellular Space / other
Apobec1 / apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 / 2.3 / 2.6E-03 / Cytoplasm / enzyme
Apobec2 / apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 / -11.1 / 5.4E-05 / Other / enzyme
Apol10b / apolipoprotein L 11a / 4.5 / 3.2E-04 / Other / other
Apol7e / apolipoprotein L 7e / 16.6 / 8.0E-03 / Other / other
Apol9a / apolipoprotein L 9b / 3.5 / 5.0E-02 / Other / other
Apol9b / apolipoprotein L 9b / 4.8 / 1.9E-04 / Other / other
Aqp7 / aquaporin 7 / -6.0 / 1.0E-02 / Plasma Membrane / transporter
Aqp9 / aquaporin 9 / 2.1 / 3.0E-02 / Plasma Membrane / transporter
Areg / amphiregulin / 8.4 / 1.6E-09 / Extracellular Space / growth factor
Arg2 / arginase 2 / 5.2 / 4.7E-10 / Cytoplasm / enzyme
Arhgap20 / Rho GTPase activating protein 20 / -2.8 / 2.0E-02 / Cytoplasm / other
Arhgef9 / Cdc42 guanine nucleotide exchange factor (GEF) 9 / -2.4 / 1.8E-04 / Cytoplasm / other
Armcx1 / armadillo repeat containing, X-linked 1 / -2.3 / 2.3E-05 / Other / other
Armcx6 / armadillo repeat containing, X-linked 6 / -2.3 / 5.4E-04 / Other / other
Arnt2 / aryl-hydrocarbon receptor nuclear translocator 2 / 5.3 / 7.3E-08 / Nucleus / transcription regulator
Arntl / aryl hydrocarbon receptor nuclear translocator-like / -2.5 / 2.3E-04 / Nucleus / transcription regulator
Arsj / arylsulfatase family, member J / -2.6 / 2.0E-03 / Extracellular Space / enzyme
Art1 / ADP-ribosyltransferase 1 / -7.7 / 3.6E-04 / Plasma Membrane / enzyme
Art3 / ADP-ribosyltransferase 3 / -2.7 / 7.1E-10 / Plasma Membrane / enzyme
Art5 / ADP-ribosyltransferase 5 / -4.3 / 4.0E-02 / Extracellular Space / enzyme
Asb15 / ankyrin repeat and SOCS box containing 15 / -3.5 / 5.0E-02 / Nucleus / transcription regulator
Asgr1 / asialoglycoprotein receptor 1 / -5.7 / 3.7E-10 / Plasma Membrane / transmembrane receptor
Aspn / asporin / -3.0 / 3.2E-05 / Extracellular Space / other
Asz1 / ankyrin repeat, SAM and basic leucine zipper domain containing 1 / -28.9 / 5.0E-02 / Nucleus / transcription regulator
Atf3 / activating transcription factor 3 / 3.1 / 1.0E-04 / Nucleus / transcription regulator
Atp1a2 / ATPase, Na+/K+ transporting, alpha 2 polypeptide / -2.3 / 3.4E-07 / Plasma Membrane / transporter
Atp1b1 / ATPase, Na+/K+ transporting, beta 1 polypeptide / 2.1 / 5.4E-05 / Plasma Membrane / transporter
Atp2a1 / ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 / -3.6 / 3.4E-03 / Cytoplasm / transporter
Atp2c2 / ATPase, Ca++ transporting, type 2C, member 2 / -2.2 / 2.9E-04 / Cytoplasm / enzyme
Atp6v0a4 / ATPase, H+ transporting, lysosomal V0 subunit a4 / 4.3 / 5.3E-04 / Cytoplasm / transporter
Atp6v0d2 / ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2 / 2.3 / 8.1E-07 / Cytoplasm / transporter
Atp6v1g3 / ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3 / 5.7 / 6.0E-05 / Cytoplasm / transporter
Auts2_1 / 2.2 / 7.0E-04
Avpr1a / arginine vasopressin receptor 1A / -2.7 / 2.0E-02 / Plasma Membrane / G-protein coupled receptor
Awat1 / acyl-CoA wax alcohol acyltransferase 1 / 102.0 / 5.7E-15 / Other / other
B2m / beta-2-microglobulin / 2.1 / 1.4E-08 / Plasma Membrane / transmembrane receptor
B3galt5 / UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5 / 3.9 / 4.0E-02 / Cytoplasm / enzyme
B3gnt7 / UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7 / 2.4 / 1.7E-07 / Cytoplasm / enzyme
B4galnt4 / beta-1,4-N-acetyl-galactosaminyl transferase 4 / 5.3 / 1.0E-03 / Extracellular Space / enzyme
Batf3 / basic leucine zipper transcription factor, ATF-like 3 / 3.9 / 6.2E-06 / Nucleus / transcription regulator
BC021614 / cDNA sequence BC021614 / 2.3 / 5.4E-07 / Other / other
BC023105 / cDNA sequence BC023105 / 14.7 / 7.8E-05 / Other / other
BC030867 / chromosome 17 open reading frame 53 / 20.3 / 1.2E-10 / Other / other
BC051142 / cDNA sequence BC051142 / 3.3 / 4.7E-04 / Nucleus / other
BC061194 / cDNA sequence BC061194 / 10.6 / 2.4E-03 / Nucleus / other
Bche / butyrylcholinesterase / -3.6 / 6.0E-07 / Plasma Membrane / enzyme
Bcl2a1b / BCL2-related protein A1 / 2.5 / 1.4E-05 / Cytoplasm / other
Bcl2l15 / BCL2-like 15 / 7.5 / 9.5E-11 / Nucleus / other
Bcl2l2 / BCL2-like 2 / -2.4 / 2.9E-08 / Cytoplasm / other
Begain / brain-enriched guanylate kinase-associated / -2.4 / 2.1E-03 / Nucleus / other
Best3 / bestrophin 3 / -2.7 / 2.0E-03 / Nucleus / ion channel
Bhlha15 / basic helix-loop-helix family, member a15 / 3.9 / 1.6E-05 / Nucleus / transcription regulator
Bhlhe40 / basic helix-loop-helix family, member e40 / 3.2 / 1.8E-07 / Nucleus / transcription regulator
Bhlhe41 / basic helix-loop-helix family, member e41 / 2.6 / 1.0E-05 / Nucleus / transcription regulator
Bmp6 / bone morphogenetic protein 6 / -2.1 / 4.0E-02 / Extracellular Space / growth factor
Bmp7 / bone morphogenetic protein 7 / -2.4 / 4.0E-04 / Extracellular Space / growth factor
Bmp8a / bone morphogenetic protein 8a / 9.5 / 5.5E-03 / Extracellular Space / cytokine
Bmpr1b / bone morphogenetic protein receptor, type IB / -2.1 / 7.2E-04 / Plasma Membrane / kinase
Bpifb1 / BPI fold containing family B, member 1 / -6.0 / 1.6E-03 / Extracellular Space / other
Brinp2 / bone morphogenetic protein/retinoic acid inducible neural-specific 2 / 4.1 / 1.0E-02 / Cytoplasm / other
Btnl6_1 / 33.0 / 2.0E-02
Btnl7-ps / 2.2 / 3.0E-02
C130080G10Rik / RIKEN cDNA C130080G10 gene / -8.1 / 3.1E-04 / Other / other
C1qa / complement component 1, q subcomponent, A chain / 2.1 / 1.8E-03 / Extracellular Space / other
C1qb / complement component 1, q subcomponent, B chain / 2.2 / 1.8E-03 / Extracellular Space / other
C1qc / complement component 1, q subcomponent, C chain / 2.1 / 1.4E-03 / Extracellular Space / other
C1qtnf2 / C1q and tumor necrosis factor related protein 2 / -3.0 / 2.8E-04 / Extracellular Space / other
C1qtnf9 / C1q and tumor necrosis factor related protein 9B / -2.6 / 2.0E-02 / Cytoplasm / other
C2cd4b / C2 calcium-dependent domain containing 4B / 2.1 / 5.0E-02 / Plasma Membrane / other
C3ar1 / complement component 3a receptor 1 / 2.3 / 1.6E-03 / Plasma Membrane / G-protein coupled receptor
C430049B03Rik / RIKEN cDNA C430049B03 gene / -2.2 / 3.0E-02 / Other / other
C6 / complement component 6 / 2.3 / 1.2E-06 / Extracellular Space / other
C920025E04Rik / major histocompatibility complex, class I, E / 3.1 / 2.9E-11 / Plasma Membrane / transmembrane receptor
Cacna1b / calcium channel, voltage-dependent, N type, alpha 1B subunit / -2.3 / 1.0E-02 / Plasma Membrane / ion channel
Cacna1g / calcium channel, voltage-dependent, T type, alpha 1G subunit / 2.3 / 3.0E-02 / Plasma Membrane / ion channel
Cacna1h / calcium channel, voltage-dependent, T type, alpha 1H subunit / 3.7 / 5.6E-03 / Plasma Membrane / ion channel
Cacna2d4 / calcium channel, voltage-dependent, alpha 2/delta subunit 4 / -2.2 / 5.4E-03 / Other / ion channel
Cadm3 / cell adhesion molecule 3 / 2.4 / 5.0E-02 / Plasma Membrane / other
Calml3 / calmodulin-like 3 / -2.7 / 3.0E-02 / Cytoplasm / other
Capn13 / calpain 13 / -2.8 / 2.0E-02 / Other / other
Capn6 / calpain 6 / -3.2 / 5.2E-06 / Cytoplasm / peptidase
Car3 / carbonic anhydrase III, muscle specific / -6.6 / 4.0E-02 / Cytoplasm / enzyme
Casq2 / calsequestrin 2 (cardiac muscle) / -7.2 / 4.8E-06 / Cytoplasm / other
Catsperd / catsper channel auxiliary subunit delta / 2.9 / 2.0E-02 / Extracellular Space / other
Cav3 / caveolin 3 / -2.2 / 3.0E-02 / Plasma Membrane / enzyme
Ccdc129 / coiled-coil domain containing 129 / -2.1 / 3.0E-02 / Other / other
Ccdc67 / coiled-coil domain containing 67 / -2.1 / 3.0E-02 / Other / other
Ccdc83 / coiled-coil domain containing 83 / 4.0 / 8.5E-03 / Other / other
Ccl19 / chemokine (C-C motif) ligand 19 / 6.1 / 4.0E-02 / Extracellular Space / cytokine
Ccl3 / chemokine (C-C motif) ligand 3-like 3 / 2.9 / 1.0E-02 / Extracellular Space / cytokine
Ccl4 / chemokine (C-C motif) ligand 4 / 5.3 / 2.7E-03 / Extracellular Space / cytokine
Ccl6 / chemokine (C-C motif) ligand 6 / 2.7 / 6.3E-06 / Extracellular Space / cytokine
Ccl8 / chemokine (C-C motif) ligand 8 / 16.5 / 6.7E-10 / Extracellular Space / other
Ccr5 / chemokine (C-C motif) receptor 5 (gene/pseudogene) / 3.2 / 7.7E-07 / Plasma Membrane / G-protein coupled receptor
Cd14 / CD14 molecule / 2.5 / 1.0E-03 / Plasma Membrane / transmembrane receptor
Cd163 / CD163 molecule / -3.7 / 4.5E-04 / Plasma Membrane / transmembrane receptor
Cd163l1 / CD163 molecule-like 1 / 5.9 / 4.8E-06 / Plasma Membrane / other
Cd164l2 / CD164 sialomucin-like 2 / 2.6 / 2.0E-03 / Other / other
Cd177 / CD177 molecule / 6.4 / 2.3E-03 / Cytoplasm / other
Cd200r1 / CD200 receptor 1 / 2.3 / 1.6E-05 / Plasma Membrane / other
Cd200r4 / CD200 receptor 1-like / 2.6 / 9.4E-07 / Plasma Membrane / other
Cd209a / C-type lectin domain family 4, member M / -2.6 / 3.9E-03 / Plasma Membrane / other
Cd209b / CD209b antigen / -10.6 / 4.9E-06 / Plasma Membrane / other
Cd209f / CD209f antigen / -6.5 / 9.2E-08 / Other / other
Cd209g / CD209g antigen / -5.1 / 2.6E-03 / Other / other
Cd248 / CD248 molecule, endosialin / -2.3 / 3.6E-05 / Plasma Membrane / other
Cd274 / CD274 molecule / 2.3 / 2.4E-04 / Plasma Membrane / enzyme
Cd28 / CD28 molecule / 2.4 / 2.0E-02 / Plasma Membrane / transmembrane receptor
Cd300a / CD300a molecule / 2.1 / 3.6E-03 / Plasma Membrane / transmembrane receptor
Cd300lf / CD300 molecule-like family member f / 3.0 / 2.7E-06 / Plasma Membrane / other
Cd300lh / CD300 molecule-like family member d / 2.3 / 1.7E-04 / Plasma Membrane / other
Cd33 / CD33 antigen / 2.4 / 5.2E-03 / Plasma Membrane / other
Cd3e / CD3e molecule, epsilon (CD3-TCR complex) / 3.7 / 1.9E-04 / Plasma Membrane / transmembrane receptor
Cd3g / CD3g molecule, gamma (CD3-TCR complex) / 3.3 / 2.2E-03 / Plasma Membrane / transmembrane receptor
Cd4 / CD4 molecule / 2.4 / 5.0E-02 / Plasma Membrane / transmembrane receptor
Cd5 / CD5 molecule / 2.6 / 2.0E-02 / Plasma Membrane / transmembrane receptor
Cd6 / CD6 molecule / 2.4 / 1.0E-02 / Plasma Membrane / transmembrane receptor
Cd68 / CD68 molecule / 2.4 / 2.7E-11 / Plasma Membrane / other
Cd74 / CD74 molecule, major histocompatibility complex, class II invariant chain / 3.0 / 1.8E-14 / Plasma Membrane / transmembrane receptor
Cd84 / CD84 molecule / 2.0 / 1.3E-05 / Plasma Membrane / other
Cdh11 / cadherin 11, type 2, OB-cadherin (osteoblast) / -2.2 / 9.3E-05 / Plasma Membrane / other
Cdh13 / cadherin 13 / -2.1 / 4.2E-03 / Plasma Membrane / other
Cdh2 / cadherin 2, type 1, N-cadherin (neuronal) / -2.9 / 3.7E-05 / Plasma Membrane / other
Cdh22 / cadherin 22, type 2 / -3.2 / 7.2E-03 / Plasma Membrane / other
Cdkn1a / cyclin-dependent kinase inhibitor 1A (p21, Cip1) / 2.1 / 2.0E-02 / Nucleus / kinase
Cdkn1c / cyclin-dependent kinase inhibitor 1C (P57) / -2.1 / 1.4E-05 / Nucleus / other
Cdr2 / cerebellar degeneration-related protein 2, 62kDa / -2.2 / 1.8E-03 / Cytoplasm / other
Ceacam10 / carcinoembryonic antigen-related cell adhesion molecule 10 / 11.7 / 5.0E-02 / Extracellular Space / other
Cela1 / chymotrypsin-like elastase family, member 1 / 3.8 / 7.5E-05 / Extracellular Space / peptidase
Celf4 / CUGBP, Elav-like family member 4 / 2.5 / 1.6E-04 / Nucleus / translation regulator
Cfb / complement factor B / 2.0 / 2.0E-02 / Extracellular Space / peptidase
Cfd / complement factor D (adipsin) / -10.3 / 4.5E-03 / Extracellular Space / peptidase
Ch25h / cholesterol 25-hydroxylase / 2.9 / 1.1E-04 / Cytoplasm / enzyme
Chad / chondroadherin / -3.3 / 1.1E-04 / Extracellular Space / other
Chdh / choline dehydrogenase / 6.5 / 6.0E-05 / Cytoplasm / enzyme
Chi3l3 / 3.8 / 6.2E-04
Chl1 / cell adhesion molecule L1-like / 10.3 / 3.2E-04 / Plasma Membrane / other
Chst3 / carbohydrate (chondroitin 6) sulfotransferase 3 / -2.0 / 2.0E-02 / Cytoplasm / enzyme
Cideb / cell death-inducing DFFA-like effector b / 2.4 / 2.9E-03 / Cytoplasm / other
Cidec / cell death-inducing DFFA-like effector c / -3.2 / 1.6E-03 / Cytoplasm / other
Ciita / class II, major histocompatibility complex, transactivator / 2.2 / 9.9E-03 / Nucleus / transcription regulator
Cilp2 / cartilage intermediate layer protein 2 / -9.1 / 1.2E-05 / Extracellular Space / other
Ckm / creatine kinase, muscle / -11.0 / 1.7E-05 / Cytoplasm / kinase
Ckmt2 / creatine kinase, mitochondrial 2 (sarcomeric) / -14.6 / 5.8E-05 / Cytoplasm / kinase
Clca1 / chloride channel calcium activated 1 / 2.9 / 2.0E-02 / Plasma Membrane / ion channel
Cldn10 / claudin 10 / -2.3 / 9.2E-05 / Plasma Membrane / other
Cldn2 / claudin 2 / 4.8 / 3.2E-05 / Plasma Membrane / other
Cldn23 / claudin 23 / -2.3 / 2.2E-03 / Plasma Membrane / other
Clec4a2 / C-type lectin domain family 4, member A / 2.2 / 1.9E-06 / Plasma Membrane / transmembrane receptor
Clec4d / C-type lectin domain family 4, member D / 3.4 / 6.2E-03 / Plasma Membrane / other
Clec4n / C-type lectin domain family 6, member A / 2.1 / 1.1E-06 / Plasma Membrane / transmembrane receptor
Clec5a / C-type lectin domain family 5, member A / 2.2 / 1.9E-03 / Plasma Membrane / other
Clec7a / C-type lectin domain family 7, member A / 2.3 / 1.2E-04 / Plasma Membrane / transmembrane receptor
Cmya5 / cardiomyopathy associated 5 / -2.2 / 5.4E-06 / Cytoplasm / other
Cntfr / ciliary neurotrophic factor receptor / -2.4 / 2.0E-02 / Plasma Membrane / transmembrane receptor
Cntn1 / contactin 1 / -6.0 / 1.8E-04 / Plasma Membrane / enzyme
Col13a1 / collagen, type XIII, alpha 1 / -2.9 / 1.5E-09 / Plasma Membrane / other
Col17a1 / collagen, type XVII, alpha 1 / -5.8 / 6.7E-08 / Plasma Membrane / other
Col25a1 / collagen, type XXV, alpha 1 / -6.2 / 2.0E-02 / Cytoplasm / other
Col6a5 / collagen, type VI, alpha 5 / -2.2 / 4.5E-03 / Extracellular Space / other
Colec10 / collectin sub-family member 10 (C-type lectin) / -5.0 / 3.0E-02 / Cytoplasm / other
Colgalt2 / collagen beta(1-O)galactosyltransferase 2 / -2.2 / 8.5E-03 / Cytoplasm / other
Colq / collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase / -5.8 / 5.9E-07 / Extracellular Space / other
Corin / corin, serine peptidase / 5.3 / 9.6E-06 / Plasma Membrane / peptidase
Cox6a2 / cytochrome c oxidase subunit VIa polypeptide 2 / 2.1 / 5.2E-06 / Cytoplasm / enzyme
Cox8b / cytochrome c oxidase subunit VIIIb / -4.5 / 1.9E-05 / Cytoplasm / enzyme
Cpa2 / carboxypeptidase A2 (pancreatic) / -32.1 / 4.0E-02 / Extracellular Space / peptidase
Cpb1 / carboxypeptidase B1 (tissue) / -4.7 / 2.1E-03 / Extracellular Space / peptidase
Cped1 / cadherin-like and PC-esterase domain containing 1 / -2.3 / 2.7E-06 / Cytoplasm / other
Cpn2 / carboxypeptidase N, polypeptide 2 / -2.6 / 2.0E-02 / Extracellular Space / peptidase
Cpne2 / copine II / 2.4 / 1.6E-13 / Other / other
Cpxm2 / carboxypeptidase X (M14 family), member 2 / 3.8 / 1.7E-03 / Extracellular Space / peptidase
Crabp1 / cellular retinoic acid binding protein 1 / -29.6 / 6.9E-06 / Cytoplasm / transporter
Creg2 / cellular repressor of E1A-stimulated genes 2 / 8.8 / 4.0E-05 / Extracellular Space / enzyme
Crmp1 / collapsin response mediator protein 1 / 4.6 / 1.0E-02 / Cytoplasm / enzyme
Csf2ra / colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) / 2.2 / 3.5E-10 / Plasma Membrane / transmembrane receptor
Csf2rb / colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) / 2.2 / 1.2E-04 / Plasma Membrane / transmembrane receptor
Csf2rb2 / colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) / 2.3 / 2.3E-04 / Plasma Membrane / transmembrane receptor
Csmd1 / CUB and Sushi multiple domains 1 / 12.7 / 2.8E-11 / Plasma Membrane / other
Csrp3 / cysteine and glycine-rich protein 3 (cardiac LIM protein) / -9.6 / 8.9E-04 / Nucleus / other
Cst7 / cystatin F (leukocystatin) / 3.7 / 2.0E-02 / Extracellular Space / other
Ctla4 / cytotoxic T-lymphocyte-associated protein 4 / 5.3 / 8.5E-05 / Plasma Membrane / transmembrane receptor
Ctnna3 / catenin (cadherin-associated protein), alpha 3 / -5.2 / 4.0E-02 / Plasma Membrane / other
Ctsc / cathepsin C / 2.0 / 7.3E-08 / Cytoplasm / peptidase
Ctsd / cathepsin D / 2.2 / 2.7E-07 / Cytoplasm / peptidase
Ctse / cathepsin E / 3.3 / 2.0E-02 / Cytoplasm / peptidase
Ctsh / cathepsin H / 2.6 / 1.9E-11 / Cytoplasm / peptidase
Ctsk / cathepsin K / 3.2 / 6.0E-07 / Cytoplasm / peptidase
Ctss / cathepsin S / 3.0 / 1.8E-08 / Cytoplasm / peptidase
Ctsw / cathepsin W / 3.8 / 2.2E-04 / Cytoplasm / peptidase
Cttnbp2 / cortactin binding protein 2 / -3.8 / 1.4E-05 / Cytoplasm / other
Cxcl10 / chemokine (C-X-C motif) ligand 10 / 7.1 / 4.0E-03 / Extracellular Space / cytokine
Cxcl9 / chemokine (C-X-C motif) ligand 9 / 29.8 / 1.4E-08 / Extracellular Space / cytokine
Cxcr1 / chemokine (C-X-C motif) receptor 1 / 6.7 / 3.2E-07 / Plasma Membrane / G-protein coupled receptor
Cxcr3 / chemokine (C-X-C motif) receptor 3 / 4.4 / 3.0E-05 / Plasma Membrane / G-protein coupled receptor
Cxcr6 / chemokine (C-X-C motif) receptor 6 / 10.7 / 5.0E-03 / Plasma Membrane / G-protein coupled receptor
Cyb5r2 / cytochrome b5 reductase 2 / -2.9 / 4.0E-02 / Cytoplasm / enzyme
Cyp1a1 / cytochrome P450, family 1, subfamily A, polypeptide 1 / -8.7 / 2.8E-03 / Cytoplasm / enzyme
Cyp21a1 / cytochrome P450, family 21, subfamily A, polypeptide 2 / 79.7 / 9.7E-05 / Cytoplasm / enzyme
Cyp26b1 / cytochrome P450, family 26, subfamily B, polypeptide 1 / -3.8 / 4.0E-02 / Cytoplasm / enzyme
Cyp2c40 / cytochrome P450, family 2, subfamily c, polypeptide 40 / 56.4 / 8.0E-03 / Cytoplasm / enzyme
Cyp2e1 / cytochrome P450, family 2, subfamily E, polypeptide 1 / -2.9 / 2.0E-03 / Cytoplasm / enzyme
Cyp4a12a / cytochrome P450, family 4, subfamily A, polypeptide 22 / 13.0 / 3.1E-04 / Cytoplasm / enzyme
Cyp4a14 / cytochrome P450, family 4, subfamily a, polypeptide 14 / 82.9 / 2.3E-05 / Cytoplasm / enzyme
Cytl1 / cytokine-like 1 / -2.2 / 6.0E-04 / Extracellular Space / cytokine
D030028A08Rik / RIKEN cDNA D030028A08 gene / 2.8 / 2.1E-03 / Other / other
D330050G23Rik / RIKEN cDNA D330050G23 gene / 9.0 / 2.3E-04 / Other / other
D430019H16Rik / RIKEN cDNA D430019H16 gene / -2.1 / 1.2E-03 / Other / other
Darc / 7.5 / 2.3E-06
Dbp / D site of albumin promoter (albumin D-box) binding protein / 4.2 / 8.6E-03 / Nucleus / transcription regulator
Dcdc2a / doublecortin domain containing 2 / -2.3 / 2.8E-04 / Extracellular Space / other
Dclk1 / doublecortin-like kinase 1 / 2.3 / 1.9E-03 / Other / kinase
Dcstamp / dendrocyte expressed seven transmembrane protein / 5.2 / 2.0E-02 / Plasma Membrane / other
Ddah1 / dimethylarginine dimethylaminohydrolase 1 / -2.1 / 3.0E-02 / Cytoplasm / enzyme
Ddc / dopa decarboxylase (aromatic L-amino acid decarboxylase) / -2.7 / 9.6E-05 / Cytoplasm / enzyme
Derl3 / derlin 3 / 6.8 / 4.2E-07 / Cytoplasm / other
Dgkb / diacylglycerol kinase, beta 90kDa / -2.2 / 2.0E-02 / Cytoplasm / kinase
Dhrs7c / dehydrogenase/reductase (SDR family) member 7C / -12.8 / 1.5E-03 / Cytoplasm / enzyme
Dhrs9 / dehydrogenase/reductase (SDR family) member 9 / 2.1 / 4.0E-02 / Cytoplasm / enzyme
Dio2 / deiodinase, iodothyronine, type II / -2.2 / 2.0E-02 / Cytoplasm / enzyme
Dkk2 / dickkopf WNT signaling pathway inhibitor 2 / 2.4 / 2.0E-02 / Extracellular Space / other
Dmkn / dermokine / 2.5 / 3.1E-05 / Extracellular Space / other
Dmrta1 / DMRT-like family A1 / 41.9 / 4.1E-03 / Extracellular Space / other
Dnase1l3 / deoxyribonuclease I-like 3 / 4.5 / 9.1E-05 / Nucleus / enzyme
Dntt / DNA nucleotidylexotransferase / -21.5 / 3.3E-03 / Nucleus / enzyme
Dpt / dermatopontin / -2.0 / 1.1E-06 / Extracellular Space / other
Dscam / Down syndrome cell adhesion molecule / 32.9 / 5.0E-02 / Plasma Membrane / other
Dusp2 / dual specificity phosphatase 2 / 4.1 / 1.6E-03 / Nucleus / phosphatase
Dusp26 / dual specificity phosphatase 26 (putative) / -3.1 / 2.0E-02 / Cytoplasm / enzyme
Dusp27 / dual specificity phosphatase 27 (putative) / -6.5 / 3.4E-03 / Other / phosphatase
Dusp4 / dual specificity phosphatase 4 / 3.0 / 8.9E-07 / Nucleus / phosphatase
E030013I19Rik / RIKEN cDNA E030013I19 gene / -2.0 / 2.0E-02 / Other / other
E130012A19Rik / chromosome 17 open reading frame 96 / 2.2 / 5.8E-05 / Other / other
E330013P04Rik / RIKEN cDNA E330013P04 gene / 8.7 / 5.0E-02 / Other / other
Eaf2 / ELL associated factor 2 / 6.0 / 7.5E-05 / Nucleus / transcription regulator
Ear11 / 28.1 / 2.9E-03
Ebf2 / early B-cell factor 2 / -7.9 / 2.0E-02 / Nucleus / other
Ebi3 / Epstein-Barr virus induced 3 / 2.3 / 4.0E-02 / Extracellular Space / cytokine
Ecm2 / extracellular matrix protein 2, female organ and adipocyte specific / -2.5 / 4.8E-08 / Extracellular Space / other
Ecscr / endothelial cell surface expressed chemotaxis and apoptosis regulator / -2.2 / 1.1E-04 / Other / other
Edil3 / EGF-like repeats and discoidin I-like domains 3 / -2.6 / 6.8E-04 / Extracellular Space / other
Ednrb / endothelin receptor type B / -2.0 / 5.4E-03 / Plasma Membrane / G-protein coupled receptor
Eef1a2 / eukaryotic translation elongation factor 1 alpha 2 / -10.0 / 1.9E-03 / Cytoplasm / translation regulator
Efcc1 / EF-hand and coiled-coil domain containing 1 / -2.2 / 1.8E-04 / Other / other
Egln3 / egl-9 family hypoxia-inducible factor 3 / 2.4 / 4.0E-02 / Cytoplasm / enzyme
Eid1 / EP300 interacting inhibitor of differentiation 1 / -2.3 / 1.5E-03 / Nucleus / transcription regulator
Elovl7 / ELOVL fatty acid elongase 7 / 2.3 / 1.7E-07 / Cytoplasm / enzyme
Emilin2 / elastin microfibril interfacer 2 / 2.1 / 5.6E-03 / Extracellular Space / other
Emr4 / EGF-like module containing, mucin-like, hormone receptor-like sequence 4 / -2.4 / 2.0E-02 / Plasma Membrane / other
Enpp1 / ectonucleotide pyrophosphatase/phosphodiesterase 1 / 2.0 / 5.7E-04 / Plasma Membrane / enzyme
Enpp3 / ectonucleotide pyrophosphatase/phosphodiesterase 3 / -2.6 / 1.0E-02 / Plasma Membrane / enzyme
Epb4.1l3 / erythrocyte membrane protein band 4.1-like 3 / -3.0 / 6.6E-04 / Plasma Membrane / other
Ephx2 / epoxide hydrolase 2, cytoplasmic / -3.1 / 2.8E-03 / Cytoplasm / enzyme
Epn3 / epsin 3 / 2.0 / 2.3E-05 / Cytoplasm / other
Ereg / epiregulin / 45.9 / 6.2E-12 / Extracellular Space / growth factor
Ern2 / endoplasmic reticulum to nucleus signaling 2 / -4.0 / 1.0E-02 / Cytoplasm / kinase
Etv4 / ets variant 4 / 14.1 / 1.8E-14 / Nucleus / transcription regulator
Eya4 / EYA transcriptional coactivator and phosphatase 4 / -2.6 / 3.9E-04 / Cytoplasm / phosphatase
F10 / coagulation factor X / 2.5 / 1.0E-07 / Extracellular Space / peptidase
F830016B08Rik / RIKEN cDNA F830016B08 gene / 5.4 / 6.5E-04 / Other / other
F9 / coagulation factor IX / 5.3 / 3.0E-02 / Extracellular Space / peptidase
Fabp3 / fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor) / -3.3 / 3.1E-04 / Cytoplasm / transporter
Faim2 / Fas apoptotic inhibitory molecule 2 / -2.5 / 7.7E-04 / Plasma Membrane / other
Fam102b / family with sequence similarity 102, member B / 2.0 / 4.4E-07 / Other / other
Fam124b / family with sequence similarity 124B / -2.8 / 2.1E-07 / Other / other
Fam150a / family with sequence similarity 150, member A / 2.6 / 3.9E-05 / Other / other
Fam162b / family with sequence similarity 162, member B / -2.1 / 1.0E-02 / Other / other
Fam198a / family with sequence similarity 198, member A / -2.4 / 1.0E-02 / Other / other
Fam19a1 / family with sequence similarity 19 (chemokine (C-C motif)-like), member A1 / -2.3 / 1.0E-02 / Extracellular Space / other
Fam83a / family with sequence similarity 83, member A / 4.8 / 1.4E-04 / Other / other
Fasl / Fas ligand (TNF superfamily, member 6) / 5.9 / 2.2E-03 / Extracellular Space / cytokine
Fbn2 / fibrillin 2 / -3.1 / 2.0E-02 / Extracellular Space / other
Fbp2 / fructose-1,6-bisphosphatase 2 / 6.4 / 3.0E-11 / Cytoplasm / phosphatase
Fbxo40 / F-box protein 40 / -2.8 / 2.0E-02 / Cytoplasm / other
Fcamr / Fc receptor, IgA, IgM, high affinity / 2.9 / 3.3E-03 / Plasma Membrane / transmembrane receptor
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