Qindong Shi, MD, PHD

Department of Critical Care Medicine the First Hospital Affliated to Xi’an Jiaotong University

No. 277Yanta west Road Xi’an City Shaanxi Province 710061P. R. China

Office: +86-029-85323186 Mobile: +86-13700283522 E-mail:

Seeking a 3-month to 6-month Visiting Scholar opportunity in the field of Critical Care Medicine, with particular interest in Hemodynamic Monitoring and respiratory function support

PROFESSIONAL HISTORY

Deputy Chief physician, Department of Critical Care Medicine 2009– present

the First Hospital Affliated to Xi’an Jiaotong UniversityXi’an City, Shaanxi Province, China

Associate Professor of Critical Care Medicine 2009 – present

Medical School of Xi’an JiaotongUniversityXi’an City, Shaanxi Province, China

Attending physician, Department of Critical Care Medicine 2005-2009

the First Hospital Affliated to Xi’an Jiaotong UniversityXi’an City, Shaanxi Province

Attending physician, Department of Emergency Medicine 1998-2005

the First Hospital Affliated to Xi’an Jiaotong UniversityXi’an City, Shaanxi Province

RESIDIENCY HISTORY

Resident physician, Department of Internal Medicine 1992– 1997

the First Hospital Affliated to Xi’an Jiaotong University  Xi’an City, Shaanxi Province

EDUCATION HISTORY

Ph.D.,Neurobiology 2003-2009

Medical School of Xi’an Jiaotong University Shaanxi Province, China

M.S., Internal Medicine 1998-2001

Medical School of Xi’an Jiaotong University  Shaanxi Province, China

M.D., Clinical Medicine 1987-1992

Beijing University of Traditional Chinese MedicineBeijing , China

CONTINUING EDUCATION AND TRAINING

Visiting Scholar,Department of Critical Care Medicine, 05/2005-06/2005

Nanjing Zhongda Hospital, Southeast University School of MedicineNanjing City, Jiangsu Province, China

LICENSECERTIFICATE

Medical License, Serial#: 199861141110105691202545 1999

Shaanxi Province, China

FIELD OF EXPERTISE

Intensive care medicine

Especially insevere sepsis and MODS ,hemodynamic Monitoringfor severe patients, respiratory support techniquessuch as mechanical ventilation and ECMO(extracorporeal membrane oxygenation) in Acute Respiratory Distress Syndrome (ARDS), and infection control in ICU.

RESEARCH INTEREST

therapy roles of neural stem cell in hypoxic and/or ischemic brain injury

clinical study on hemodynamic monitoring and microcirculation monitoring

clinical use of antibiotics in critical care patients

RESEARCH SKILL & TECHNIQUE

Cell culture;

Molecular cloning technique;

Electron microscopy technique;

Immunohistochemistry

fluomicroscopy and laser scanning confocal microscopy technique ;

Western blot and Northern blot; ELISA;

PCR and RT-PCR

mouse and rat middle cerebral vascular occlusion model and small animal operation;

laserDopplerFlowmetry technique

RESEARCH FUNDING

The study of TMS (Transcranial MagneticStimulation) effect on adult neural stem cell

supported by“the Fundamental Research Funds for the Central Universities”

Totally 100,000 RMB 2012 to 2014

Mild hypothermia influence neurogenesis after cardiac arrest via regulation of cold shock protein CIRP and RBM3

supported by the National Science Foundation of China (No. 81460287)

Totally 490,000 RMB 2015 to 2018

PROFESSIONAL MEMBERSHIP

Intensive Care Medicine Branch 2005 – present

Shaanxi Medical Association Shaanxi Province, China

The Chinese Neuroscience Society 2003-present

Chinese Society of Critical Care Medicine, CSCCM 2005-present

AWARD & HONOR

Outstanding Physician awarded by the First Hospital Affliated to Xi’an Jiaotong University 2009

Xi’an city, Shaanxi province, China

PUBLICATION

1).JieYanga*, Qing-Dong Shi, Tian-Bao Song, Gai-FengFeng, Wei-Jing Zang, Chang-Hong Zong, Ling Chang. Vasoactive intestinal peptide increases VEGF expression to promote proliferation of brain vascular endothelial cells via the cAMP/PKA pathway after ischemic insult in vitro.Peptides. 42:105-111, 2013

2).Junfeng Zhang,Qindong Shi#, Xinlin Chen, Pengbo Yang, CunfangQi, Jianshui Zhang, HaixiaLu.Lingyu Zhao, Bingqiao Zhao, Ping Zheng, Yong Liu*. Hypoxia-regulated neurotrophin-3 expression by multicopy hypoxia response elements reduces apoptosis in PC12 cells. Int J Mol Med.;30(5):1173-9, 2012.

3). Junfeng Zhang, Qindong Shi#,Pengbo Yang, XiXu, XinlinChen,,CunfangQi,Jianshui Zhang, HaixiaLu,PingZheng, Yong Liu*. Neuprotection of neurotrophin-3 against focal cerebral ischemia/perfusion injury is regulated by hypoxia-responsive element in rats. Neuroscience; 222: 1–9, 2012

4). Lu Yao ,Xinlin Chen ,YingfangTian,Haixia Lu ,Pengbo Zhang ,Qindong Shi,Junfeng Zhang ,Yong Liu. Selection of housekeeping genes for normalization of RT-PCRin hypoxic neural stem cells of rat in vitro. Mol Biol Rep. 2012,39(1):5690

5)Shi Qindong,Wang Xue, Teng Yan , Chen Lihong, Zhang Lei, Li Hao, GuoLitao. The influence of laminar air flow wards on pathogenic bacterium of VAP in intensive care unit ICU. Chin J Nosocomiol. 2011, 21(2):392-394

6) Shi Qindong,Teng Yan, Liu Yu, Chen Lihong, Zhang Lei, Wang Xue.The influence of operator experience on percutaneous dilatational tracheostomy.J Med TheorPrac. 2011,24(2):125-1265

7). Tian Y, Liu Y, Chen X, Kang Q, Zhang J,Shi Q, Zhang H. AMN082 promotes the proliferation and differentiation of neural progenitor cells with influence on phosphorylation of MAPK signaling pathways.Neurochem Int. 2010 ;57(1):8-15.

8). Tian Y, Liu Y, Chen X, Zhang H, Shi Q, Zhang J, Yang P.Tetramethylpyrazine promotes proliferation and differentiation of neural stem cells from rat brain in hypoxic condition via mitogen-activated protein kinases pathway in vitro.NeurosciLett. 2010;474(1):26-31.

9) .Shi Qindong, Zhang Pengbo, Zhang Junfeng, Chen Xinlin, Lu Haixia,TianYumei, Parker T L, Liu Yong* . Adenovirus-mediated brain-derived neurotrophic factor expression regulated by hypoxia response element protects brain from injury of transient middle cerebral artery occlusion in mice. Neuroscience letters; 465(3):220-5,2009

10). Yang J, Zong C H, Zhao Z H,Hu X D,Shi Q D, Xiao X L, Liu Y*. Vasoactive intestinal peptide in rats with focal cerebral ischemia enhances angiogenesis. Neuroscience.161(2):413-21, 2009

11).Shi Qindong, Zhang Pengbo, TianYumei, Zhang Junfeng, Chen Xinlin, Liu Yong. Construct ion and expression ofthe eukaryotic expressionplasmid of BDNF-EGFP fusion protein. Journal of Xi’anJiaotong University(Medical Sciences).2009,30(2):141-144

12). Shi Qindong, Zhang Junfeng,ZhangPengbo,WangXue, Chen Xinlin,TianYumei,YangPengbo,ZhangJianshui, Liu Yong.Effects of human urinary kallikrein on regional cerebral blood flow of penembra following focal cerebral ischemia in rat. Chin J NervMent Dis. 2008,34(7):413-416

13). Shi Qindong, Wang Xue, Liu Hongjuan, Liu Yu, Teng Yan. Pathogenic bacterium of VAP in new intensive care unit.Chin J Nosocomiol.2008, 18(2):186-188

14).Shi Qin-dong; Zhang Peng-bo; Kang Qian-yan; Chen Xin-lin; Tian Yu-mei; Liu Jian-xin; Liu Yong. Construction and identification of a plasmid with EGFP reporter gene for enhancer function analysis.Nan fang yikedaxuexuebao.2007;27(12):1834-7

15). Zhang Pengbo, Liu Yong, Li Jie, Kang Qianyan;,TianYingfang;,ChenXinlin;,ZhaoJianjun, Shi Qindong, Song Tusheng .Decreased neuronal nitric oxide synthase expression and cell migration in the peri-infarction after focal cerebral ischemia in rats.Neuropathology . 2007;27(4):347-54.

ENGLISH ABILITY

Certificate of College English Test (CET) Class 6 1999