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MATERIAL SAFETY DATA SHEET

Date Updated: 15 Feb 11

Revision Number:MSDS 038.07

SECTION 1. PRODUCT AND COMPANY INFORMATION
Commercial Product: ALLERGY REAGENTS - RIA Tracer
Name: Anti-human IgE and IgG Tracer
List Number(s): 71201, 71239, 72005, 307037, 307040, 307043, 307178, 307179, 307180, 187038, 187039.
Product Classification: In vitro diagnostic device
Manufacture Company:
HycorBiomedical Inc.
7272 Chapman Ave
Garden Grove, CA92841
U.S.A. / PentlandSciencePark
Bush Loan, Penicuik EH26 OPL
United Kingdom
Emergency Telephone No.:
USA (714) 933-3000 Attention: Solmaz Shaida (Mgr., Quality)
Europe /United Kingdom: + 44 (0) 131 445 7111 Danielle D’Souza (Mgr., Quality)
SECTION 2. COMPOSITION / INFORMATION ON INGREDIENTS
Character: Product contains 0.095% Sodium Azide. Sodium iodide Iodine (I-125) (≤10µCi/vial).
Hazardous substances (chemical): sodium azide, Sodium iodide Iodine (I-125)
See EEC directive 67/548/EEC and amendments.
Substance / %w/w / Health Class / CAS No. / EINECS No. / ANNEX 1
Sodium azide (sodium azoture) / 0.095% / T+; N R:28-32-50/53
S: (1/2)-28-45-60-61 / 26628-22-8 / 247-852-1 / 011-004-00-7
See section 16 for spelling of R and S phrases.
SECTION 3. HAZARDS IDENTIFICATION
Classification: Product is chemically classified as no chemical dangerous preparation.
Radioactivity exposure.
SECTION 4. FIRST AID MEASURES
Eye Contact: Promptly wash eyes with water for at least 15 minutes, seek medical advice.
Skin Contact: Flush skin with copious amounts of water. Monitor for residual radioactivity. Remove contaminated clothing.
Ingestion: Drink large volumes of water. Seek medical aid for radiation.
Inhalation: Move to fresh air and stand upwind if outside. Seek immediate medical attention for I-125 thyroid intake
Direction for Physician: Symptomatic treatment by a physician.
Commercial Product: ALLERGY REAGENTS - RIA Tracer
SECTION 5. FIRE-FIGHTING MEASURES
Extinguishing Media: No restriction
Special Fire Fighting Procedures: N/A
Unusual Fire Fighting Procedures: N/A
Thermal Decomposition: Do not heat to decomposition.
SECTION 6. ACCIDENTAL RELEASE MEASURES
Steps To Be Taken After Spillage: 1) Cordon off the suspected area of contamination.
2) Determine the area of contamination by monitoring after taking the necessary precautions.
3) Isolate contaminated area using vermiculite or charcoal.
4) Do not dilute, this will spread the radiation.
5) Starting from the outer edge, decontaminate the area in convenient sections by wiping or scrubbing.
6) Before moving on, ensure that a sector is clean by monitoring.
7) Dispose of all radioactive waste according to statutory requirements
Waste Disposal Method: Observe all Federal and State laws concerning clean-up or disposal of radioactive material.
Follow instructions on the site license or as directed by local Radiation Control Officer.
SECTION 7. HANDLING AND STORAGE
Handling: Refer to product package insert.
Respiratory Protection: Air purifying respirator with combination radio-nuclide cartridge or SCBA where spill has occurred.
Storage: Store between +2C and +8C.
Other Precautions: N/A
SECTION 8. EXPOSURE CONTROLS/PERSONAL PROTECTION
Product TLV: Not known.
Sodium azide TLV (pure substance): 0.29 mg/m3 (Ceiling)
Respiratory Protection: None
Eye Protection: Protective chemical safety goggles where splashing is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Hand Protection: One-way gloves. Wash hands before breaks and disinfect them at end of the work.
Other Protective Equipment: Protective Clothing
SECTION 9. PHYSICAL AND CHEMICAL PROPERTIES
PhysicalState: Liquid
Color: N/A
Odor: N/A
pH Value: 7.5-8.0
Boiling Point: N/A
Melting Point: N/A
Flash Point: N/A / Ignition Temperature: N/A
Explosion limits: N/A
Vapor Pressure: N/A
Solubility In Water: Soluble
Viscosity: N/A
Commercial Product: ALLERGY REAGENTS- RIA
SECTION 10. STABILITY AND REACTIVITY
Hazardous Reactions: None known when used appropriately.
Hazardous Decomposition Products: Sodium azide may react with lead and copper plumbing. On disposal flush with large amounts of water.
Sodium Iodine I125 half-life 60 days
SECTION 11. TOXICOLOGICAL INFORMATION
LD50 Oral: Not known
LD50: Not known
LD50 Skin: Not known
LD50 Inhalation: Not known / Referred to Sodium azide (in pure form)
LD50 Oral (rat): 27 mg/kg
LD50 Oral (mouse): 27 mg/kg
LDLO Oral (woman): 14 mg/kg
LDLO Oral (man): 29 mg/kg
LC50 Inhalation (rat): 37 mg/m3
LD50 Skin (rat): 50 mg/kg
LD50 Skin (rabbit): 20 mg/kg
LD50 Subcutaneous (rat): 45100 g/kg
LD50 Intravenous (rat): 47500 g/kg
IARC category: none
Toxicological Information: Toxic substance, exposure to radioactivity.
SECTION 12. ECOLOGICAL INFORMATION
Use product according with good laboratory practices and avoid to release to the environment.
Ecotoxicity (aquatic toxicity): Product contains 0.095% sodium azide. Sodium azide concentration is below EC directives allowed limits (0,25%, w/w). So, product is classified as no harmful to the aquatic environment, according to the legislation in force (1999/45/CE and amendments). However, cause sodium azide LC50/96H values for fish are less than 1 mg/L, do not empty product into water or drains.
Mobility: Product is not expected to selectively partition and absorb to soil or sediments.
Persistence and Degradability: when released into the soil, or into water, this product is not expected to persist in the environment.
Bioaccumulative potential: The product is not expected to significantly bioaccumulations
Other adverse effects: None
SECTION 13. DISPOSAL CONSIDERATIONS
Observe all Federal, State and Local laws concerning clean up or Disposal of Radioactive material.
SECTION 14. TRANSPORT INFORMATION
Transport in accordance with national and international regulations.
Is not subject to current regulations for transportation of hazardous goods (eg.GGUS/ADR, GGUE/RID, IMDG,
IATA/ICAD.
Do not compromise container integrity.
SECTION 15. REGULATORY INFORMATION
Hazard Symbol: R
Warnings: See section on Hazardous Identification. Monitor yourself upon working with radioactive material.
Precautions: After contact with skin, wash immediately with plenty of soap and water.
Commercial Product: ALLERGY REAGENTS- RIA
SECTION 16. OTHER INFORMATION
The information herein is believed to be correct as of the date hereof but is provided without warranty of any kind. The recipient of our products is responsible for observing any laws and guidelines applicable.
Use the product according with box insert and MSDS information. Please, read well instructions for use and warning.
Legend:
R phrases:
R 28: Very toxic if swallowed
R 32: Contact with acids liberates very toxic gas
R 50/53: Very toxic to aquatic organisms may cause long-term adverse effects in the aquatic environment.
S phrases:
S 1/2:Keep locked up and out of the reach of children
S 28: After contact with skin, wash immediately with plenty of water
S 45: In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible)
S 60: This material and its container must be disposed of as hazardous waste
S 61: Avoid release to the environment. Refer to special instructions/safety data sheets

MSDS 038.0715/02/2011