"PROGETTO HHS - I.I.S "GIORDANO BRUNO" PERUGIA " A.S. 2011 -2012

English teacher ______Pritee Tembhekar______

REGISTRO ATTIVITA' MODULO CLIL: SVOLGIMENTO LEZIONI IN COMPRESENZA CON INSEGNANTI ITALIANI - CON METODOLOGIA CLIL

CLASS_4A______SUBJET______chemistry______ITALIAN TEACHER______Stefania Primieri______

DATE / CLASS / TOPICS / LESSON PLAN / TEACHING STRATEGIES / SOURCES / RESOURCES
1/11/12 / 4A / Cell structure- view under the microscope / Onion cell lab- students made their own wet mounts of onion skin cells and observed the cells under the microscope / Hands on observation
Recording lab observations / / -cell1. Ppt presentation
-Youtube video
-Onion cell lab handout
1/12/12 / 4A / Detailed view of cell structure- organelles / Present recent MIT article
Go over all the organelles / Themes in biology- Coming up with the links between structure and function
Current research shows application of theories
Visualizing (drawings of the cell presented)
Students created new metaphors to cement understanding / / Cellstructure2.Ppt presentation
1/13/12 / 4A / Cell cycle and regulation points / Go over cell cycle basics and then have students apply it to cancerous cells / Convey information and then have students apply the information in new ways
Students “think like cancer” (how cancer cells overcome checks on replication to replicate uncontrollably) / Cellcycle3.Ppt presentation
1/18/12 / 4A / Cell cycle and regulation / Present a hypothesis and ask how the students would test it, describing the materials that could be used and asking for the data and experimental set up required / Let the students design novel experiments and then discuss the strengths and weaknesses of the experiments
Practice brainstorming
Practice problem solving
Practice group work / Campbell and Reece Biology textbook / Cellcycle3.Ppt presentation
1/19/2012 / 4A / Anchorage dependence, contact inhibition,
Introduction to drug design / Discuss why Anchorage dependence, contact inhibition is important for normal cells
Discuss the basics of drug design / Let students come up with ideas to explain natural phenomena
Emphasize how past lessons culminated in last time’s experimental design
Introduce/foreshadow upcoming concepts
Present simple example of complex subject
Link to real world (getting a cold, bacterial infection) /
/ Cellcycle3.Ppt
Introduction to Drug Design4.ppt
1/20/2012 / 4A / Rational drug design / Discuss the design of enzyme inhibitors and their use / Guide students to the design of an enzyme inhibitor
Use simplified diagrams of complex structures
Show the full scientific picture to describe complexity and how it can be broken down
Group work to recap lesson / / RationalDrugDesign.ppt
1/23/2012 / 4A / Details of drug design (Part 1) / Amino Acids, primary secondary, tertiary structure, quaternary structure / “Zoom in”- break down the complex picture into its parts and explain how each works
Student participation / DetailsofRationalDrugDesign.ppt
1/25/2012 / 4A / Details of drug design (Part 2) / Connection back to cancer
MutationCancer progression / Entire scientific process
Explanation of the source of natural phenomenon / DetailsofRationalDrugDesign.ppt
1/25/2012 / 4A / Gleevec- A case study / Real world antitumor drug / Connection to real world treatment
Group work
Problem solving and explanation / Chart of amino acids / CaseStudy1.ppt
1/26/2012 / 4A / Gleevec (conclusion, sharing answers)
Telomerase RNAi / What does a telomerase do?
Why are they especially important to cancer?
How can we use this information to make an anticancer drug? / Theory linked to application
Problem solving
Application to practical problems (how do you actually make RNA, deliver it etc) / Telomerase.ppt
RNAi.ppt
1/26/2012 / 4A / RNAi / New technologies (continued)- RNAi / Thinking about advantages and disadvantages of a new technologies /
/ RNAi.ppt
1/27/2012 / 4A / Drug delivery / Using hydrogels and nanoparticles for drug delivery / Thinking about advantages and disadvantages of a new technologies
Practical vs. theoretical thinking /
/ DrugDelivery.ppt
1/27/2012 / 4A / Drug delivery (continued) / Further explanation of drug delivery
Different applications of hydrogels based on my research in the Olsen Lab at MIT / Thinking about advantages and disadvantages of a new technologies
Practical vs. theoretical thinking / DrugDelivery.ppt
1/27/2012 / 4A / Cancer Conclusion Activity drugs / What’s happening at MIT and around the world
Need for collaboration
Cancer vs. Cancer Drugs student skit / Show the bigger picture
Future of Science
Make cutting edge science interesting
Active learning- students acted out what they had learned / Cancer-Conclusion.ppt