Disodium Ascorbyl Phytostanol Phosphate. a New Cholesterol-Lowering Drug?

European Journal

of Clinical Pharmacology

Volume 64 ■ Number 7 • July 2008

EDITORIAL COMMENTARY

Disodium ascorbyl phytostanol phosphate. A new cholesterol-lowering drug?

K, von Bergmann 649

CLINICAL TRIAL

Efficacy and safety of disodium ascorbyl phytostanol phosphates in men with moderate dyslipidemia

M.N. Vissers ■ M.D. Trip ■ P.H. Pritchard • P. Tarn ■ T. Lukic ■

M.G. de Sain-van derVelden ■ M. de Barse ■ J.J.P. Kastelein 651

PHARMACOGENETICS

Impact of genetic polymorphisms of leptin and TNF-a on rosiglitazone response in Chinese patients with type 2 diabetes

H.-L Liu ■ Y.-G. Lin ■ J. Wu ■ H. Sun • Z.-C Gong ■ P.-C. Hu ■ J.-Y.Yin ■ W.Zhang ■ D.Wang ■ H.-H. Zhou ■ Z.-Q. Liu 663

Association of slow N-acetyltransferase 2 profile and anti-TB drug-induced hepatotoxicity in patients from Southern Brazil

L.G. Possuelo ■ J.A. Castelan T.C. de Brito ■ A.W. Ribeiro ■

P.f. Cafrune ■ P.D. Picon ■ A.R. Santos ■ R.LF.Teixeira ■

T.S. Gregianini ■ M.H. Hutz ■ M.L.R. Rossetti ■ A. Zaha 673

PHAEMACOKINETICS AND DISPOSITION

Pharmacokinetics and tolerability of artesunate and amodiaquine alone and in combination in healthy volunteers

C. Orrell ■ F. Little ■ P. Smith ■ P. Folb ■ W.Taylor ■ P. Olliaro ■ K.I. Barnes 683

The effect of fluvoxamine on the pharmacokinetics, safety, and tolerability of ramosetron in healthy subjects

T. Kadokura-M. den Adel ■ WJJ. Krauwinkel T.Takeshige-A.Nishida 691

Effect of the novel antipsychotic drug perospirone on P-glycoprotein function and expression in Caco-2 cells

Y.-G. Zhou ■ K.-Y. Li ■ H.-D. Li 697

How many subjects are necessary for population pharmacokinetic experiments? Confidence interval approach

K. Ogungbenro ■ L. Aarons 705

PHARMACOEPIDEMIOLOGY AND PRESCRIPTION

Factors predicting hospital readmissions related to adverse drug reactions

B. Ruiz ■ M. Garcia ■ U. Aguirre ■ C. Aguirre 715

Safety aspects of iodinated contrast media related to their physicochemical properties: a pharmacoepidemiology study in two Tuscany hospitals

F. Lapi ■ E. Cecchi ■ C. Pedone ■ F. Attanasio ■ G. Banchelli ■ A. Vannacci ■ M. Di Pirro ■ M. Moschini ■ V. Berni ■ R. Matucci ■ E. Cini • A. Scalia ■ E. Tendi ■ A. Mugelli 723

LETTER TO THE EDITORS

A reversible coma after oxaliplatin administration suggests a pathogenetic role of electrolyte imbalance

M. Basso ■ A. Cassano ■ A. Modoni ■ D. Spada ■ N. Trigila ■ M. Quirino ■ G. Schinzari ■ C. Barone 739

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