PubMed and the Evidence-Based Universe

Quick Quiz

  1. How is Evidence-Based Medicine best described?
  1. Research evidence on large patient populations for producing clinical practice guidelines
  2. A managed care organizational process setting practice standards for provider networks
  3. Integrating the best research evidence with clinical expertise and individual patient values
  4. A purely statistical approach used to determine clinical decision making
  5. A technique used by lawyers in prosecuting malpractice cases
  1. What components are required for a good randomized control trial?
  1. Heterogeneous patient populations, confidence intervals, multiple authors
  2. Homogeneous patient populations, study validity measures, statistical relevance
  3. Study validity measures, multiple authors, identifying funding sources
  4. Study validity measures, statistical relevance, multiple authors
  5. Study validity measures, statistical relevance, clinical significance
  1. A study investigating an effect of a new drug for decreasingblood pressure should be a study of type:
  1. Double-blind placebo–controlled study
  2. Retrospective cohort study
  3. Prospective case–control study
  4. Cross-sectional
  1. Internal validity may be described as:
  1. The experiment is performed within the institution
  2. A prospective cohort study
  3. The experiment uses a control group
  4. A study is able to answer the questions it is intended to answerscientifically
  1. External validity may be defined as:
  1. The study was evaluated by referees
  2. The study has been accepted for publication
  3. The results may be generalized to the entire population from which the sample was drawn
  4. The study has been replicated
  1. You are investigating risk factors for a very rare disease. Which type of study you should you choose in order to obtain results most effectively and quickly?
  1. Case–control study
  2. Clinical trial
  3. Cross-sectional observational study
  4. Prospective cohort study
  1. Intention to treat may be defined as:
  1. The investigators intend to use the results of their study on a cohort of patients
  2. “Analyze where you randomize”
  3. A drug company has sponsored the study
  4. Both the placebo group and the interventional group took the drug
  1. Randomization is used to avoid:
  1. Selection bias
  2. Confounding variables
  3. Generalization
  4. Validity
  1. Which one of the following is the highest level of evidence?
  1. Article on a non-randomized clinical trial that includes references
  2. Case series article that has been peer-reviewed
  3. Cochrane review
  4. Detailed report of a clinical case
  1. Which of the following statements best describes a PICO?
  1. Checklist of guidelines to assist investigators with the reporting of the findings from a meta-analysis
  2. Process for converting a clinical problem into an answerable question that can be answered by searching for evidence
  3. Defines a specific MeSH heading and provides synonyms covered by that heading
  4. Technique for combining search terms in order to restrict a search to articles with specified elements

This project has been funded in whole or in part with Federal funds from the National Library of Medicine,

National Institutes of Health, Department of Health and Human Services,

under Contract No. HHS-N-276-2011-00005-C with the University of Illinois at Chicago.