Supplementary material

Table 1: Weight and content of the fractions obtained by column chromatography of the dewaxed foliar rinse extract (8,7 gr) of 500 g of leaves from population number 16 of S. macroscyphus (Rearte, Trancas, Tucumán). Approximately 53% corresponds to sesquiterpene lactones (STLs).

Fraction / Weight (gr) / Content / GC/MS
1 / 0.057 / - / -
2-5 / 1.128 / - / -
6 / 0.552 / kaurenoic acid and derivatives / -
7 / 1.326 / kaurenoic acid
STL / 1 / 10%
90%
8-14 / 2.465 / STL / 1 / 99%
15-18 / 0.366 / STL / 4
1
5 / 28%
25%
32%
19 / 0.008 / STL / 5
4 / 70%
15%
20-22 / 0.096 / STL
sterols / 5 / 59%
40%
23-27 / 0.263 / STL / 4
5
1 / 37%
58%
5%
28-30 / 0.102 / STL
others / 5
- / 10%
31-54 / 0.436 / - / -
55-113 / 1.378 / Smaditerpenic acid / -
total / 8.177 gr (94%)

Table 2: Weight and content of the fractions obtained by column chromatography of the dewaxed foliar rinse extract (350 mg) of 20 g of leaves from population number 2 of S. macroscyphus (Argentinian-Bolivian border). Approximately 56% corresponds to STLs.

Fraction / Weight (mg) / Content / GC/MS
1-2 / 43 / Others
Kaurenoic acid / -
3 / 22 / STL / 2
9 / 98%
2%
4 / 21 / STL / 2
10 / 46%
54%
5 / 28 / STL / 10
11 / 94%
6%
6-10 / 113 / STL
Other STL (under study) / 10 / 9
91%
11-16 / 23 / STL
others / 10 / 10%
90%
17-23 / 81 / Smaditerpenic acid
others / -
total / 331 mg (95%)