Curriculum Vitae
of
Douglas Edward Barre
Curriculum Vitae of Douglas Edward Barre Continued
Address : 25 Carmichael Drive,
Sydney, N.S.,
B1S-3K4
Telephone Number : Work (Office) - 902-563-1921
(Laboratories) - 902-563-1977
902-563-1151
Home - 902-564-6810
Fax Number : 902-563-1880
E-mail Address :
Nationality : Canada / United Kingdom and Northern Ireland
Marital Status : Married with two children
Education
Department College Dates Attended
Research Fellow Department of Cardiology University of Texas, Southwestern July 1994
Medical Center at Dallas, TX, USA -May 1995
Post-doctoral Fellow Center for Human Nutrition University of Texas, Southwestern June 1992
Medical Center at Dallas, TX, USA -June 1994
Ph.D. Nutritional Sciences University of Guelph, Guelph
Ontario, Canada 1992
-Thesis Title- The effect of Borage Oil Consumption on Human Plasma Lipids and Platelet Reactivity and Platelet Phospholipid Compositions
Ph.D. (withdrew) Physiological Optics University of Waterloo, Waterloo,
Ontario, Canada 1987
M.Sc. Kinanthropology University of Ottawa, Ottawa, Ontario, Canada 1984
-Thesis Title-The Effect of Acute and Chronic Endurance Exercise on High Density
Lipoprotein Cholesterol and the HDL-cholesterol: Total Serum Cholesterol Ratio
Hons. B.Sc. Biology Queens University, Kingston, Ontario, Canada 1977
Curriculum Vitae of Douglas Edward Barre Continued
Research Skills
Determination of plasma lipid(cholesterol, triglycerides, individual and total free fatty acids), lipoprotein lipids(HDLc, HDL2c, HDL3c, LDLc, small dense LDLc, total Lp(a), lipoprotein sizing by NMR and polyacrylamide gels, glucose, insulin, glycosylated haemoglobin and plasma individual total and free fatty acids via HPLC and UPLC(H-class)-MS-MS-photodiode array detection and quantitation, ELISAs for (adiponectin, high sensitivity (hs) -C-reactive protein, enterolactione, hs-interleukin-6, hs-tumour necrosis factor-alpha, oxidized LDL, lipoprotein(a), albumin and leptin), gas-liquid chromatography, lipid extraction, thin-layer chromatography, radioimmunoassay for PGE1, PGE2 and TxB2, incorporation of radio-labelled lipid into lipoproteins, iodination (125I and 131I) of apolipoproteins and fibrinogen, competitive binding studies on cell receptors ultracentrifugation and dialysis for lipoprotein isolation; apo A-I, apo B, llipoprotein sizing by polyacrylamide gels, LDL clearance studies in transgenic mice, LDL turn-over studies, LDL oxidation, Lp(a) isolation by column chromatography; use of Coulter counter for platelet counts; determination of protein content by the Lowry and Bradford methods; elution of plasma eicosanoids and limited experience with their HPLC isolation; platelet aggregation; cell culture; DNA isolation and sequencing; gene and other genomic region copy number variants, gene expression using real time PCR, primer extension analysis of DNA sequence; polymerase chain reaction; reverse transcriptase-polymerase chain reaction (RT-PCR);designing oligonucleotide sequences using Oligo version 4.0 from National Biosciences; purification of DNA after amplification; internal 32P labelling for SSCP and restriction endonuclease assessment of allelic substitution; end 32P labelling of oligonucleotides; paper chromatography assessment of the extent of 32P labelling for SSCP and restriction endonuclease assessment of allelic substitution; restriction endonuclease genotyping of amplified DNA; assessment of alleles and their co-segregation with lipid and protein levels by agarose gel containing ethidium bromide and polyacrylamide gels; single strand conformation polymorphism (SSCP) analysis; denaturing gel analysis of length polymorphisms; autoradiography of SSCP and denaturing gels; cloning; sub-cloning; transfection; bacterial plasmid mini-preps; adenovirus recombinant DNA construction; limited experience with epidemiology including nutritional epidemiology, nutritional surveys, liposome preparation and in vivo delivery, enzymology, Northern, Southern and Western blotting, plasma apolipoprotein levels; limited experience with DOS pertaining a fatty acid analyses composition and HPLC analysis of eicosanoid content of human plasma, extensive experience with PC compatible programmes such as MS-Word, -Excel and -Powerpoint, Statview, SigmaPlot, and Deltagraph, nucleotide sequence searches on Genbank and EMBL
Curriculum Vitae of Douglas Edward Barre Continued
Research Skills continued
using Entrez, restriction maps derived from DNA Strider on Macintosh, extensive experience with SAS, various Macintosh text editing and graphics programmes. Limited conceptual knowledge of immunoblotting,
immunoprecipitation, electroporation, construction and use of cDNA libraries, chromosome walking and jumping ,site directed mutagenesis, translation assays, promoter and enhancer activity studies using the CAT reporter gene.
Honours
The University of Waterloo Graduate Scholarship - $500 awarded in January, May and September 1985 and January and May 1986
Baxter Renal Award-$100 awarded in January 1999 for an idea to significantly improve peritoneal dialysis. Nominated in July 1999 for an outstanding contribution award in the renal technical community.
Journal of Oleo Science (Japanese Oil Chemists Society) Impact Award for 2009 – 50,000 yen (600 dollars Canadian) - awarded in September 2010 for most citations in 2009 in different journals for my article - Barre, D.E. 2007. The role of consumption of alpha-linolenic, eicosapentaenoic and docosahexaenoic acids in human metabolic syndrome and type 2 diabetes- A mini-review. J. Oleo Science. 56: 319-325.
Grants
Sole applicant
May 2011- $750-SSRA grant-Determination of blood plasma enterolactone levels and their correlation with changes seen in glucose management and platelet reactivity in human type 2 diabetics consuming flaxseed lignan complex”.
April 2011-$1600 - awarded by Cape Breton Health Research Centre “The effect of bolus consumption and continuous sipping of a glucose solution with and without vitamin C consumption on markers of oxidation in men and women”.
April 2011-$7000- awarded by Cape Breton-University-RAP grant-“Blood plasma enterolactone assay for the flaxseed lignan complex trial in human type 2 diabetics”
May 2010- $492-SSRA grant-“Development of method for measuring metabolites of flaxseed lignan complex in human blood plasma of type 2 diabetics”.
May 2010-$5529 - awarded by Cape Breton Health Research Centre -“Interleukin-6 and Tumour Necrosis Factor-alpha assays and measures of drug compliance in human type 2 diabetics consuming flaxseed lignan complex”
April 2010-$6997- awarded by Cape Breton-University-RAP grant-“Flaxseed lignan complex impact on interleukin-6 and tissue necrosis factor-alpha concentrations (plus refrigerator purchase)”
June 2009- $1000- for developing research skills-awarded by Nova Scotia Health Research Foundation under their Capacity Building-Special Consideration Award Programme-allowed for the purchase of DNA dedicated pipets
May 2009-$293.80- awarded by Cape Breton-University-SSRA grant-“Nutrigenetics of cholesterol responsiveness to flaxseed lignan complex in type 2 diabetics
April 2009- $8000- awarded by Cape Breton Health Research Centre -“Flaxseed lignan complex administration in human type 2 diabetics”
March 2009--$6999.14- awarded by Cape Breton-University-RAP grant-“Nutrigenetics of cholesterol responsiveness to flaxseed lignan complex in type 2 diabetics and purchase of a tube rotator”
September 2008-$35000 ($15000 year 1, $15000 year 2 and $5000 year 3)- awarded by the Agricultural Bioproducts Innovation Programme (Agriculture Canada) “ Clinical trial using flaxseed lignan complex in type 2 diabetics”
May 2008 -$303.03- awarded by Cape Breton-University-SSRA grant-“Development of a novel high performance liquid chromatographic (HPLC) method for quantification of all individual serum fatty acids including trans-fatty acids in type 2 diabetics”
Curriculum Vitae of Douglas Edward Barre Continued
Grants continued
Sole applicant continued
May 2008-$4996.57- awarded by Cape Breton-University-RAP grant-“HPLC method development for total blood serum fatty acids including trans fatty acids in type 2 diabetics, pH meter purchase, and summer student help”
July 2007-$10000 awarded by Nova Scotia Health Research Foundation- Developmental/Innovation grant- for a pilot study “Impact of Flaxseed Lignan Complex in Type 2 Diabetics”
July 2007-$56574-awarded by CFI-Infrastructure operating funds grant in support of June 2002 CFI grant
May 2007-$1317.00 for developing research skills-awarded by Nova Scotia Health Research Foundation under their Capacity Building Programme-allowed for the purchase of a digital camera and microwave oven
May 2007-$603.02 -awarded by Cape Breton University-SSRA grant-“Apolipoprotein E genotyping in Type 2 Diabetics”
May 2007-$4998.56 -awarded by Cape Breton University-RAP grant-“Apolipoprotein E genotyping in Type 2 Diabetics”
May 2006-$701.75 -awarded by Cape Breton University-SSRA grant-“Development of an HPLC Method to Determine the Blood Plasma Individual Free Fatty Acids Composition in Human Type 2 Diabetics”
May 2006-$4778.00-for research-awarded by Cape Breton University-RAP grant- “Power Pack and Transilluminator Purchase”
March 2006-$1951.00 for developing research skills-awarded by Nova Scotia Health Research Foundation under their Capacity Building Programme-this allowed for the purchase of an orbital shaker.
November 2005-$4862.00 for research-awarded by Cape Breton University-RAP grant- “Eppendorf Tube Rotor for the High Speed Centrifuge”
May 2005 -$672.98-for research- awarded by Cape Breton University-SSRA grant-“Development of an HPLC method to measure glycosylated hemoglobin”
May 2005- $4976.00 awarded by Cape Breton University-RAP grant- “Funding for improving the efficiency of the nutraceutical laboratory”
February 2005- $1875.00 for developing research skills-awarded by Nova Scotia Health Research Foundation under their Capacity Building Programme-this allowed for the purchase of a digital logging scale.
June 2004-$596-for research- awarded by the Cape Breton University-SSRA grant-“Additional funding to expand the number of parameters for the current flax oil trial in type 2 diabetes”
May 2004- $4678.00-for research-awarded by the Cape Breton University-RAP grant-“Additional funding to expand the number of parameters for the current flax oil trial in type 2 diabetes”
July 2003-$892.00 for a student technician (September 2003-March 2004)-awarded by CBU Registrar-special fund for student employment
June 2002-$1015 for a summer student-awarded by Human Resources Development Canada
June 2002-$188,578 for equipment to perform nutraceutical experiments-awarded by the Canadian Fund for Innovation- partner contributions brought the total for this grant to $471,446
June 2002-$800.00 for a student technician (September 2002-March 2003)-awarded by CBU Registrar-special fund for student employment
May 2002-$15088 for research –awarded by Cape Breton University- funds derived from Canadian Institutes for Health Research (CIHR) institutional grant to Cape Breton University
May 2001- $1500 for research-awarded by the University of Saskatchewan
Grants
Co-applicant
Bierenstiel M, MacQuarrie, S and Barre E. November 2010-UPLC-MS-MS/PAD: Liquid Chromatography Mass Spectrometry Instrumentation for Multidisciplinary Applications in Chemistry Research and Nutrition Science-CFI contribution of $315,000-partner contributions brought the total for this grant to $-$792,200 (Barre’s share 264,000)
Curriculum Vitae of Douglas Edward Barre Continued
Professional Societies
Membership in the Canadian Society for Nutritional Sciences. Membership in the American Heart Association (AHA) Scientific Council for Basic Science and a fellow of the AHA Council for Arteriosclerosis.
Employment
Sabbatical 1 July 2008-30 June 2009
Vice Chair School of Professional Studies -1 July 2011-30 June 2013
Associate Professor Department of Health Studies (vice-chair-1 October 2005-present),
School of Professional Studies,
Cross appointed to Chemistry (School of Science and Technology)
Cape Breton University
Sydney, Nova Scotia
B1P 6L2
Dates 1 October 2005-present
Duties
Teach nutrition at the undergraduate level (introductory (Nutrition 261), applied(Nutrition 263), community nutrition(Nutrition 101), current issues in human nutrition(Nutrition 361), nutritional assessment-theory(Nutrition 205), nutritional assessment-application(Nutrition 207)), human metabolism (Nutrition 265), develop new courses, participate in departmental administrative and committee work, pursue research and scholarly activities, and complete other duties assigned by the Deans and department heads.
Associate Professor School of Education, Health and Wellness
Cape Breton University
Sydney, Nova Scotia
B1P 6L2
Dates 1 July 2005-30 September 2005
Duties
Teach nutrition at the undergraduate level (introductory (Nutrition 261), applied(Nutrition 263), community nutrition(Nutrition 101), current issues in human nutrition(Nutrition 361), nutritional assessment-theory(Nutrition 205), nutritional assessment-application(Nutrition 207)), human metabolism (Nutrition 265), develop new courses, participate in departmental administrative and committee work, pursue research and scholarly activities, and complete other duties assigned by the Dean and department head.
Tenure granted-1 July 2005
Assistant Professor Department of Biology
(Tenure Track) Cape Breton University
Sydney, Nova Scotia
B1P 6L2
Dates 1 July 2004-30 June 2005
Duties
Teach nutrition at the undergraduate level (introductory (Nutrition 261), applied(Nutrition 263), community nutrition(Nutrition 101), current issues in human nutrition(Nutrition 361), nutritional assessment-theory(Nutrition 205), nutritional assessment-application(Nutrition 207)), human metabolism (Nutrition 265), develop new courses, participate in departmental administrative and committee work, pursue research and scholarly activities, and complete other duties assigned by the Dean and department head.
Curriculum Vitae of Douglas Edward Barre Continued
Employment continued
Assistant Professor Department of Behavioural and Life Sciences
(Tenure Track) Cape Breton University
Sydney, Nova Scotia
B1P 6L2
Dates 1 September 2002-30 June 2004
Duties
Teach nutrition at the undergraduate level (introductory (Nutrition 261), applied(Nutrition 263), community nutrition(Nutrition 101), current issues in human nutrition(Nutrition 361), nutritional assessment-theory(Nutrition 205), nutritional assessment-application(Nutrition 207)), human metabolism (Nutrition 265), develop new courses, participate in departmental administrative and committee work, pursue research and scholarly activities, and complete other duties assigned by the Dean and department head.
Courses:
October 2002-Took a course (1.5 hours) on the use of the RADAR (Recruitment, Admission Demographics, Academic Record, and Retention) website. This website is directed at data acquisition pertaining to faculty and students at CBU.
Adjunct Professor Department of Human Nutrition,
St. Francis Xavier University,
Antigonish, Nova Scotia
B2G-2W5
Dates 28 May 2002 -present
Duties Contribute to a mutually supportive faculty relationship
Assistant Professor Department of Behavioural and Life Sciences
(Term) Cape Breton University
Sydney, Nova Scotia
B1P- 6L2
Dates 1 August 2001-31 August 2002
Duties
Teach nutrition at the undergraduate level (introductory(Nutrition 261), applied(Nutrition 263), and community nutrition(Nutrition 101), develop new courses, participate in departmental administrative and committee work, pursue research and scholarly activities, and complete other duties assigned by the Dean and department head.
Courses:
October 2001-Developing a teaching dossier-offered by the Teaching and Learning Centre at the Cape Breton University (CBU).
Curriculum Vitae of Douglas Edward Barre Continued
Employment continued
Assistant Professor College of Pharmacy and Nutrition
(Term Faculty) University of Saskatchewan
Saskatoon, Saskatchewan
S7N 5C9
Dates August 1, 2000 – June 30, 2001
Duties
Teach at the undergraduate (introductory nutrition(Nutrition 120), current issues in nutrition(Nutrition 420) and graduate level ((recent advances in nutrition(Nutrition 810)), participate in College administrative and committee work, pursue research and scholarly activities, and complete other duties assigned by the Dean. Served as departmental library liason.
Courses:
September 2000 - 3 day course in the orientation to teaching programme offered by the University of Saskatchewan.
December 2000 -1.5 hour course on web based courses offered by the University of Saskatchewan teaching and learning centre
January 2001 -2 hour course in teaching large classes offered by the University of Saskatchewan teaching and learning centre
-peer consultant review of my teaching completed by University of Saskatchewan teaching and learning centre
- attended a lecture by Dr. Steele to observe techniques used in large classes to improve teaching- such observation proposed by the University of Saskatchewan teaching and learning centre
Research Scientist Baxter Renal Division
1620 Waukegan Road
McGaw Park
IL 60085
Dates June 1995 – August 2000
Objectives
Preparing and presenting scientific papers. Conduct preclinical research and manage a laboratory for the investigation and development of peritoneal dialysis solutions and other treatments to improve lipid disorders and cardiovascular disease in renal patients.
Responsibilities
Developing experimental protocols for in vitro and in vivo studies to further the above objectives.
Performing assays and experimental analyses.