From,

DR PURUSHOTHAM PATIL

Preliminary M. D. (Ayu) Scholar,

Department of Post Graduate Studies in Shareera Rachana,

N.K.J.A.M.C. & P.G. Centre,

BIDAR- 585403.

To,

The Registrar,

Rajiv Gandhi University of Health Sciences,

BANGALORE, Karnataka.

Through,

The Principal and H.O.D, P.G. studies in Shareera Rachana ,

N.K.J.A.M.C. & P.G. Centre,

BIDAR- 585403.

Subject: Submission of Completed Proforma for Registration of Synopsis of Dissertation.

Respected Sir,

I request you to kindly register the below mentioned subject against my name for the submission of the dissertation to the Rajiv Gandhi University of Health Sciences, Bangalore, for partial fulfilment of M.D. (Ayu) in Shareera Rachana.

THE TITLE OF DISSERTATION:

“A STUDY OF ROMAKUPA SHAREERA w.s.r. TO INDRALUPTA”

I am enclosing completed proforma for Registration of Subject of dissertation.

Thanking You,

Yours faithfully,

Date:

Place: Bidar. (DR PURUSHOTHAM PATIL)

RAJIV GANDHI UNIVERSITY OF HEALTH SCIENCES

RAJIV GANDHI UNIVERSITY OF HEALTH SCIENCES

KARNATAKA-BANGALORE

ANNEXURE-II

PROFORMA FOR REGISTRATION OF SUBJECT FOR

DISSERTATION

•  Name of the Candidate: DR PURUSHOTHAM PATIL

Address: HNO. 8-10-185, KRISHNA KUTEER, GANESH MAIDAN, BIDAR, 585401.

•  Name of Institution N.K.J. AYURVEDIC MEDICAL COLLEGE &

P.G.CENTRE, BIDAR- 585403.

KARNATAKA (INDIA).

3. Course of study and Subject M.D. (SHAREERA RACHANA)

4. Date of Admission to Center 28-10-2010

5. Title of the topic

“A STUDY OF ROMAKUPA SHARIRA w.s.r. TO INDRALUPTA”

6.  BRIEF RESUME OF THE INTENDED WORK

6.1  NEED FOR THE STUDY

The rachana shareera lays fundamental basis for all the eight disciplines of our science. {ashtanga ayurveda}. A scholar who is well versed with the minutest elements of rachana shareera will have excellent diagnostical skills. Comprehensive studies have been taken with regard to twak shareera by various scholars and institutions. But whereas the structure of roma-koopa is restrained within the classical texts, it has not been explored any further but paradoxically the problem concerning to roma koopa are emerging cosmetologically significant. This study on roma-koopa shareera will assist us to establish a evidence based approach towards the fundamentals of roma-koopa shareera approved by our acharyas, The incidence and prevalence of indralupta (alopecia areata) affects about 3 -5% of human population. 65% of those afflicted with alopecia areata may go on to develop alopecia totalis within a span of 3 to 6 months and 2% of them may attain alopecia universalis(1), although it is a harmless and painless condition that does not affect ones physiology, many don’t think alopecia is worth medical attention but because society has placed so much emphasis on appearance, it is distressing and embarassing to the individuals who suffer from this, it can significantly affect body image,self esteem and sexuality,this may cause the person to limit social activities leading to anxiety,This long standing state of depression may further detoriate the physiology of an individual.

•  Alopecia, although has a low annual incidence but has a very large prevalence rate because the treatments that are available currently have yielded temporary success“As the number of hair follicles we are born with have to last us a lifetime, we cannot generate new hair follicles in any further course of our life(2), thus the discoveries and modern methods have not come up with a treatment that is cosmetically acceptable.

•  Hair weaving could only temporarily retain the hair, where as Hair transplantation is a an invasive procedure with varied results and the very advanced hair cloning method have led to uneven distribution of hair patern and all thes above measures are to be supplemented with cortico-steroids,

The side-effects of these methods, however outweigh the benefits,

•  Therefore A need based treatment approach is needed and ayurveda has a large scope in addressing this issue, so a basic understanding of roma-koopa shareera and normal hair development is essential in distinguishing normal versus abnormal hair loss.This study on roma-koopa will assist further to evaluate the efficacy of drugs pertaining to the chikitsa of khalitya,palithya,ruhya and indralupta..

6.2 REVIEW OF LITERATURE

1). Acharya sushruta has mentioned about roma-koopa- (3)

a) Amoung the 24 dhamanis originating from nabhi, 4 of them which run obliquely gets divided thousand times and thus becomes innumerable, these open up into the hair follicles.(3a)

b) Shareera under goes kshaya every moment but roma koopa doesn’t.(3b) c) roma are asthi mala.(3c).

(d) In nidana sthana the cause and diagnosis of indralupta was mentioned along with khalitya and ruhya while explaining the kshudra roga’s.(3d) (f) Sira-vyada followed by rasayana therapy is advised in order to eliminate indralupta completely (3e)

2). Acharya kashyap has mentioned in shareera adhyaya that: (4)

a) There are 2,00,000 koopa’s and same number of roma are present on human body

b) The total number of roma-koopas is determined by birth, remain same there after.

c) The ratio of koopas in Male:Female is 1 : ¾

3) Acharya Vagbhatt has opined :

a) roma koopa has been as triyak marga in raktapitta (5a)

b)closure of hair follicles along termination of any further hair growth as arishta lakshana.(5b)

4) Acharya charak has enumerated the total number of kesha, smashru and romakoopa as 29956 and they are subjected to change only in diseased condition .He has also explained the relevancy of roma in arista laxana. (6a,6b)

5)Acharya Sharangdhara has mentioned kesha as mala of shukra(7a) and also precisely explained the treatment methodologies for indralupta.(7b)

LIST OF PREVIOUSLY DONE RESEARCH WORK (DISSERTATION)

•  Pal Surendra- Twak vivechan-National Institute of Ayurveda Rajasthan University, Jaipur, 1986.

•  Badruk. P.A- A detail study of Ayurvedic concept of twak shareera in relation with modern science and structural changes in the hairy and non hairy external diseased skin, Tilak Ayurveda Mahavidyalaya, Pune University, Pune, 1997.

•  Bhusunde Abhaya Vasant- Twak staronka adhyayana kilasa vyadhi ke vishesha sandarbha mein – R.K. Toshniwal Ayurvedic Mahavidyalaya, Amaravati University, Akola, 2003.

•  Patil Deepak S- A detail study of susrutokta twak shareera and related vyadhi w.s.r to Mashaka vyanga- Tilak Ayurveda Mahavidyalaya, Pune University, Pune, 2004

6.3 OBJECTIVES OF THE STUDY

•  To study the structure of romakupa .

•  To study indralupta from ayurvedic and modern science perspective.

7.1 SOURCES OF DATA

•  Literary and conceptual study will be undertaken by the data compilations from ayurvedic samhitas, including journals, presented papers, previous work done and the same is correlated, analysed with the knowledge of contemporary science of the subject.

•  A minimum of 30 patients will be selected for the study. Digital photographs of the patchy scalp would be taken, Structural variations will be studied with the help of trichological analysis using trichogram.

7.2 METHOD OF COLLECTION OF DATA

•  Literary works,thesis,journals, including articles published on the concept related to subject will be collected and analysed scientifically.

•  Patient should be selected from OPD of the hospital attached to NKJAMC, Bidar and other hospitals in the city.

DESIGN OF THE STUDY

A.  Clinically diagnosed 30 patients of indralupta are taken for the proposed study.Gross appearance of the patch would be picturized ,physical nature of the patch would be observed.

B.  Structural changes involving the cortex, medulla and the bulb of the hair root

C.  Trichological analysis of each patient will be taken to assess the structural changes in indralupta patients i.e.effected area of the scalp.

SELECTION CRITERIA

INCLUSION CRITERIA-;

•  Diagnosed patients of indralupta.

•  Patients of all age group irrespective of gender.

EXCLUSION CRITERIA-;

•  Systemic diseases.

•  Skin reactions if any.

•  Burn.

•  Leprosy.

•  Chemotherapy induced alopecia.

•  Trauma/injury to the structure

•  Carcinoma

ASSESSMENT CRITERIA

•  patients of indralupta are diagnosed by observing the pattern of hair loss,

•  Follicular changes in the patch that occurs in the scalp.

•  Structural changes will be observed through trichological analysis and correlated with anatomical features.

7.3 INVESTIGATIONS

•  Routine Blood examination.

•  Routine Urine examination

•  Trichological analysis using trichogram.

7.4 HAS ETHICAL CLEARENCE BEEN OBTAINED FROM YOUR INTITUTION- YES

8 LIST OF REFERENCES

1.  Dr. Geoffrey Redmond M.D., Complex traits don’t follow Mendel’s law, Centre for endocrinology studies, Newyork

2.  Caraka samhita shareera sthana 7/ 10, 323pp*

3.  Vaidya Yadavji Trikamji Acharya, Sushruta samhita of Sushruta, Varanasi, Chaukhamba surbharati prakashan, Uttar Pradesh, Reprint-2008.

(a)  Shareera sthana 9/8-9, 384pp.

(b)  Shareera sthana 4/60-61, 360pp

(c)  Sutra sthana 46/529, 253pp

(d)  Nidana sthana 13/33-34, 322pp

(e)  Cikitsa sthana 20/24-26, 479pp.

4.  P.V.Tiwari, Kashyap samhita or Vriddhajeevakiya tantra, Varanasi, Chaukhambha Visvabharati, Uttar Pradesh, Reprint- 2006

Shareera sthana 4/25-27, 78pp

5.  Dr. Annamoreshwar Kunte, AsthangaHridaya of Vagbhata, Varanasi, Chaukhambha surbharati academy, Uttar Pradesh, Reprint- 2010.

a)  Nidana sthan 3/7, 467pp

b)  Shareera sthana 5/16, 419pph

6.  Vaidya Yadavji Trikamji Acharya, Charaka samhita of Agnivesha, Varanasi, Chaukhamba surbharati prakashan, Uttar Pradesh, Reprint- 2011.

(a)  Shareera sthana 7/14, 338pp

(b)  Indriya sthana 8/9, 367pp

7.  Prof. K.R.Srikanta murthy, Sharangdhar samhitha, Varanasi, Chaukhamba orientalia, Uttara Pradesh chap 11/20-34, 238pp

9. SIGNATURE OF THE CANDIDATE :DR.PURUSHOTHAM PATIL

10. REMARKS OF THE GUIDE :

11. NAME & DESIGNATION OF :

11.1 GUIDE : DR.ASHWINI KUMAR

11.2 SIGNATURE :

11.3 CO-GUIDE : DR.VIJAY KUMAR

11.4 SIGNATURE

11.5 HEAD OF DEPARTMENT : DR.N.G.MULIMANI

11.6 SIGNATURE :

12. 12.1 REMARKS OF THE CHAIRMAN :

& PRINCIPAL

12.2 SIGNATURE :