Ofer Markman
P. O. Box 1085
76110 Rehovot,
Israel.
Email: ;
Functional summary
A biochemist Ph.D. specialized in Glycobiology Biochemistry and Protein structural biology.
Founder of ProCognia (UK/Israel) Ltd. Formerly Glycodata. Had been with it through all cycles of financial rounds: Seed, post seed $600K, first VC round $5.5M, second $18.3M and current to a total of over$30M dollars.
Worked under various management systems in industrial and academic environments.
Walked through all the Industrial R&D positions (Scientist, Project manager, Head, VP).
Knowledgeable in IP strategies and IP management.
Education
Boston College, Department of Chemistry -Merkert 1990-1995
Chemistry Center Chestnut Hill, MA. USA.
Ph. D. Degree in Chemistry, awarded Dec. 1996. Adviser Dr. M. M. Teeter
Thesis title: Solution studies of plant thionins homologous to crambin: towards the understanding of biological activity.
Feinberg Graduate School - Weizmann Institute of Science 1989-1990
Rehovot , Israel
M. Sc. Degree in the Life Sciences. Advisers Dr. A. Yonath and Dr. I. R. Cohen
Thesis title: interaction between DM-idiotypic anti-insulin antibodies and insulin by solid phase methods: solid phase RIA, co-crystallization and crystal solution antibodies interactions.
Ben Gurion University, Beer Sheva, Israel 1986-1988
B. Sc. Degree in Biology and Molecular Biology.
Employment
NutriCognia Ltd subsidiary of Solbar Industries IL 2004 to today
Chief Scientific Officer and co-founder
ProCognia (Israel) R&D branch of Procognia Ltd. UK 2002
VP New Technology development, Co-Founder
Glycodata Ltd. 2000
Chief Scientist , Co-founder
Healthcare Technologies Ltd. 1998-1999
Project Manager, Head Glycobiology
Department of Physiology - Hadassah-Medical School. 1997
Jerusalem Israel
Post doctoral position in Prof. Baruch Minke's Group. Focused on post translational modification and understanding protein-protein interactions.
Department of Oncology - Hadassah-University Hospital. 1996
Tumor Biology Unit
Post doctoral position in Prof. Israel Vlodavsky's Group. Focused on the use of phage display technology in combination with nested PCR in cloning of proteins of novel sequences and activities.
Boston College - Department Of Chemistry 1991-1995
Chestnut Hill, MA, USA.
Working in research in the process of pursuing a Ph. D.Degree in Biochemistry-Biophysics.Teaching assistant in a graduate level laboratory course in advanced techniques in Biochemistry.
Professional memberships
A member of the American Glycobiology Society
Member of the British Biochemical Society
List of Publications Ofer Markman 2004
Publications (non published conference poster abstracts not included)
Proposal for molecular mechanism of thionins deduced from physico-chemical studies of plant toxinsB. Stec, O. Markman*, U. Rao, G. Heffron, S. Henderson, L.P. Vernon, V. Brumfeld and M.M. Teeter
http://www.blackwell-synergy.com/links/doi/10.1111/j.1399-3011.2004.00187.x/full/
O. Markman, Glycoinformatics challenges 2003 in Bioinformatics (eds. Rubin and Sechbach) Kluver 2004.
O. Markman, I. Paleiov, Z. Ravid, A. Morag (1997) MASDA: Multiple Antigen / Antibody Serological Detection Assay. J. Tumor Marker Oncology, 12 (1997) 115
O. Markman, C. Roh, M. F. Roberts, M. M. Teeter. (1996) Designed additives for controlled Growth of crystals of phospholipid-interacting proteins: short chain phospholipids. J. Cryst. Growth 160 (1996) 382-388
P. Friedman, R. Haimovitz, O. Markman, M. F. Roberts and M. Shinitzky (1996) Conversion of Lysophospholipids to cyclic lysophosphatidiv acid by phospholipase-D. J. Biol. Chem 271 (1996) 953-7.
L. Lobb, B. Stec, E. K. Kantrowitz, A. Yamano, V. Stojanoff, O.Markman, M. M. Teeter. Expression, Purification and Characterization of Recombinant Crambin. Protein Engineering 9 (1996), 1233-9 .
O. Markman, , D. Elias, L. Addadi, I. R. Cohen and Z. Berkovitch-Yellin (1993) Monoclonal antibodies to insulin and to insulin receptor (Anti-id) modify the morphologies of insulin crystal. J. Cryst. Growth 122 (1993)
344-350.
O. Markman, , U. Rao, K. A. Lewis, G. J. Heffron, B. Stec & M. M. Teeter (1993) Mode of phospholipid binding to the membrane active plant toxin phoratoxin-A. New Develpoments in Lipid-Protein Interactions and Receptor Function. (Eds Wirtz et al.) Nato ASI Series A246, 263-274.
Short Papers and work in Progress
O. Markman and M. M. Teeter (2002) Residue Based Analysis of NMR Constraints: a tool for assessing protein NMR structure. Abstract published in Protein Science,4 (1) 98 1995
M. M. Teeter, O. Markman , U. Rao, ( in preparation, 2002) Homology based model for the N-terminal fragment of vimentin. Submitted to the PSB meeting 2002
B. Stec, U. Rao, O. Markman , G. Heffron K. A. Lewis, V. Brumfeld, S. Henderson, M. M. Teeter (in preparation 2002) Phospholipid binding to the plant toxins. X-ray crystallography and solution studies. Abstract published: Biophysical J. (1993) 64 (2,2) p. A 61
Patents
Markman, O., and Paleiov, I, "Multi Antigen Serological Diagnostics" Israeli Patent Application No. 117605 from 21.3.96 (pending), PCT 3.1997
Markman, O PCT Application No. PCT/IL00/00256, entitled “POLYSACCHARIDE STRUCTURE AND SEQUENCE DETERMINATION”, filed on May 4, 2000 Publication No. WO0068688 Australia, NZ, Israel, Europe, US, Canada, Singapore, Japan.
Markman, O et al. PCT Application No. PCT/US00/30402, entitled “METHOD AND COMPOSITION FOR ANALYZING A CARBOHYDRATE POLYMER,” filed on November 3, 2000, Publication no. WO 0184147
4 other patents for Glycodata/Procognia together with various authors pending publication.
Theses
Ofer Markman, A Dissertation for Ph.D. in Chemistry, The Graduate School of Arts and Sciences, Boston College1996.
Adviser Dr. M. M. Teeter
Thesis title: Solution studies of plant thionins homologous to crambin: towards the understanding of biological activity.
Ofer Markman M. Sc. thesis in the Life Sciences. The Weizmann Institute of Science 1990
Advisers Dr. A. Yonath and Dr. I. R. Cohen
Thesis title: interaction between DM-idiotypic anti-insulin antibodies and insulin by solid phase methods: solid phase RIA, co-crystallization and crystal solution antibodies interactions
Other Activities, Publications, and Networking Resources:
Member of the steering committee of the Israeli Sugar Knowledge Center in Ben Gurion U., Beer Sheva – a National Resource Knowledge Center for the Ministry of Science. 2002- current.
Member of the Advisory board of NuAce Technologies Ltd. Rehovot An Israeli life Science company
Founder: The Virtual Institute of Experimental Biology http://info.md.huji.ac.il/biology/who.html
GeneCards Web Review: Human TRP (Transient Receptor Potential)
The Glycosciences Web Resources Consortium co-founder http://www.vei.co.uk/TGN/glycores/
Advisor to GNA http://www.gnacademy.org/ 1997
Active Member of Internet biologists http://www.internetbiologists.org/ and a lecturer in BRI and DBRI