Questions from Clinical Trials

Phase Questions

Questions from Clinical Trials:

1. What is the purpose of a Clinical Trial?

A. To test a drug on animal cells to see if it is safe to test on humans

B. To test a drug on humans to see if it is safe and effective

C. To evaluate a clinic and see if it is safe

D. To discover basic scientific knowledge

2. Where do scientists and medical professionals do research?

A. Universities

B. Government Labs

C. Corporations

D. All of the Above

3. What is a fake drug or treatment, such as a pill,with no active ingredient in it?

A. Medication

B. Placebo

C. Protocol

D. Potential Drugs

4. Which type of research is performed with animals usually by scientists before the Clinical Trial?

A. Clinical Research

B. Pre-clinical Research

C. Post-clinical Research

D. Trial and Error Research

5. Trials typically last how long?

A. Days

B. Years

C. Weeks

D. Hours

6. Phase I of Clinical Trial Research typically includes:

A. Testing on lab animals

B. Testing on large groups of humans

C. Testing for safety on a small group of humans

D. Testing on cells of animals

7. What is the purpose of a Sponsor for a Clinical Trial?

A. Provide money and support for the research

B. Provide advertising for the research

C. Provide people who will be subjects for the research

D. Provide the idea for the research

8. How do researchers get people to be in the Clinical Trial?

A. People who are sick with a disease have no choice and must participate

B. People volunteer to participate

C. People are not used in Clinical Trials, only animals

D. All of the above

9. What is the main difference between Phase II and Phase III in Clinical Trials?

A. There is a different drug or treatment tested

B. Phase II is on animals and Phase III is on humans

C. The drug has to be approved by the FDA before Phase III

D. Phase III involves many more people than Phase II

10. What is a Double Blind Trial?

A. The patient does not know whether or not he is receiving the drug

B. The researcher does not know which patients are receiving the drug

C. Both the researcher and the patients do not know who is receiving the drug

D. Only blind people are allowed in the trial

11. How much does it cost to do a Clinical Trial on a single drug?

A. Several hundred dollars

B. Several thousand dollars

C. Many millions of dollars

D. Many billions of dollars

12. Which of these can be a sponsor of a Clinical Trial?

A. Physician or Individual

B. National institutes of Health

C. Department of Defense

D. All of the above

13. If the Clinical Trial is a veterinary study, which subjects will be used as patients?

A. Humans

B. Animals

C. Cells only

D. There are no Veterinary Clinical Trials

14. Phase I of Clinical Trials usually includes how many people?

A. 20-80 people

B. 100-300 people

C. 1,000-3,000 people

D. It is not done on people, only animals

15. What happens after Phase III of the clinical trials?

A. The drug may be used as a treatment or prevention everywhere

B. The drug must undergo testing on animals

C. The researcher applies for approval to market the drug

D. All of the above

16. What is the biggest barrier to completing studies?

A. Having a good enough idea to start with

B. Finding a place for research

C. The shortage of people who take part

D. It takes too long to finish

Questions from Pre-Clinical Trials:

17. What is a Bioassay?

A. A “live” system that can be used to measure drug effect

B. A paper about biology

C. A scientific hypothesis

D. A suitable environment for living cells

18. The Initial New Drug (IND) must do all of the following except:

A. Show how the drug is manufactured

B. Show how the drug will be formulated

C. Show how the drug will taste

D. Show how the drug will appear

19. Discovering new facts about how things work, how they are made, or what causes a biological event to happen is which type of research?

A. Applied Research

B. Volunteered Research

C. Basic Research

D. Acclaimed Research

20. When developing a new drug discovery, what is the first step in the Pre-Clinical Trial?

A. File for approval as an Investigation New Drug

B. Screen chemical compounds in assay

C. Develop a bioassay

D. Get idea for a drug target

21. A series of chemical reactions within a cell or living organism is called:

A. Biochemical Pathway

B. Biological Pathway

C. Building Pathway

D. Drug Development Pathway

22. All of the following are examples of a bioassay except:

A. A culture of cells

B. Organs

C. An entire animal

D. Rocks

23. Using basic research information and investigating how to use it to treat and prevent sicknesses is which type of research?

A. Applied Research

B. Volunteered Research

C. Basic Research

D. Acclaimed Research

College of Veterinary Medicine & Biomedical Sciences, TexasA&MUniversity

Funding support from the NationalCenter for Research Resources, National Institutes of Health