Electronic Supplemental Material A. Search Histories (Performed 24March 2014)

ELECTRONIC SUPPLEMENTAL MATERIAL A. SEARCH HISTORIES (PERFORMED 24MARCH 2014)

Table A-1. Medline Search History

Search / Query / Items Found
#1 / Search("Venous Thrombosis"[MeSH] OR "Pulmonary Embolism"[MeSH] OR "Thromboembolism"[MeSH] OR "Arthroplasty, Replacement, Knee"[MeSH] OR "Knee Prosthesis"[MeSH] OR "Arthroplasty, Replacement, Hip"[MeSH] OR "Hip Prosthesis"[MeSH])Filters:Publication date from 2008/01/01 to 2014/03/24 / 34655
#2 / Search(“Apixaban” OR “Dabigatran” OR “Edoxaban” OR “Rivaroxaban”)Filters:Publication date from 2008/01/01 to 2014/03/24 / 2521
#3 / Search(cost effective*[Text Word] OR cost-effective*[Text Word] OR “modeling”[Text Word] OR “modelling”[Text Word] OR economic model*[Text Word] OR (model*[Text Word] AND (cost*[Text Word] OR economic*[Text Word] OR pharmacoeconomic*[Text Word])) OR “markov model”[Title] OR “markov-model”[Title] OR “decision-analytic models” OR “cost-consequence” OR “cost consequence” OR “discrete event simulation” OR “discrete-event simulation”)Filters:Publication date from 2008/01/01 to 2014/03/24 / 152233
#4 / Search(#1 AND #2 AND #3) Filters:Publication date from 2008/01/01 to 2014/03/24 / 47

MeSH=Medical Subject Heading.

Table A-2.Cochrane Search History

Search / Query / Items Found
#1 / #1 MeSH descriptor: [Venous Thrombosis] explode all trees 2223
#2 MeSH descriptor: [Pulmonary Embolism] explode all trees 887
#3 MeSH descriptor: [Thromboembolism] explode all trees 1625
#4 MeSH descriptor: [Arthroplasty, Replacement, Knee] explode all trees 1474
#5 MeSH descriptor: [Knee Prosthesis] explode all trees541
#6 MeSH descriptor: [Arthroplasty, Replacement, Hip] explode all trees 1480
#7 MeSH descriptor: [Hip Prosthesis] explode all trees 1006
#8 #1 or #2 or #3 or #4 or #5 or #6 or #7 6986 / 6986
#2 / #9 Apixaban or Dabigatran or Edoxaban or Rivaroxaban (Word variations have been searched) 495 / 495
#3 / #10 cost next effective* or modeling or modelling or economic next model* or "decision-analytic models" or "cost-consequence" or "cost consequence" or "discrete event simulation" or "discrete-event simulation" or model* and (cost* or economic* or pharmacoeconomic*) or "markov model" or "markov-model":ti (Word variations have been searched) 77134 / 77134
#4 / #11 #8 and #9 and #10 Publication Date from 2008 to 2014 40
Cochrane Reviews: 9 (9 imported)
Other Reviews: 8 (8 imported)
Trials: 4 (3 imported)
Technology Assessments: 1 (1 imported)
Economic Evaluations: 18 (13 imported) / 40

MeSH=Medical Subject Heading.

Table A-3.EconLit Search History

Search / Query / Items Found
#1 / #1 MeSH descriptor: [Venous Thrombosis] explode all trees 2223
#2 MeSH descriptor: [Pulmonary Embolism] explode all trees 887
#3 MeSH descriptor: [Thromboembolism] explode all trees 1625
#4 MeSH descriptor: [Arthroplasty, Replacement, Knee] explode all trees 1474
#5 MeSH descriptor: [Knee Prosthesis] explode all trees541
#6 MeSH descriptor: [Arthroplasty, Replacement, Hip] explode all trees 1480
#7 MeSH descriptor: [Hip Prosthesis] explode all trees 1006
#8 #1 or #2 or #3 or #4 or #5 or #6 or #7 6986 / 6986
#2 / #9 Apixaban or Dabigatran or Edoxaban or Rivaroxaban (Word variations have been searched) 495 / 495
#3 / #10 cost next effective* or modeling or modelling or economic next model* or "decision-analytic models" or "cost-consequence" or "cost consequence" or "discrete event simulation" or "discrete-event simulation" or model* and (cost* or economic* or pharmacoeconomic*) or "markov model" or "markov-model":ti (Word variations have been searched) 77134 / 77134
#4 / #11 #8 and #9 and #10 Publication Date from 2008 to 2014 40
Cochrane Reviews: 9 (9 imported)
Other Reviews: 8 (8 imported)
Trials: 4 (3 imported)
Technology Assessments: 1 (1 imported)
Economic Evaluations: 18 (13 imported) / 40

MeSH=Medical Subject Heading.

ELECTRONIC SUPPLEMENTAL MATERIAL B. UPDATED SEARCH HISTORIES (PERFORMED 13 FEBRUARY 2015)

Table B-1. Medline Search History

Search / Query / Items Found
#1 / ("Venous Thrombosis"[MeSH] OR "Pulmonary Embolism"[MeSH] OR "Thromboembolism"[MeSH] OR "Arthroplasty, Replacement, Knee"[MeSH] OR "Knee Prosthesis"[MeSH] OR "Arthroplasty, Replacement, Hip"[MeSH] OR "Hip Prosthesis"[MeSH])AND ("2014/03/24"[Date - Entrez]: "3000"[Date - Entrez]) / 1877
#2 / (“Apixaban” OR “Dabigatran” OR “Edoxaban” OR “Rivaroxaban”)AND ("2014/03/24"[Date - Entrez]: "3000"[Date - Entrez]) / 776
#3 / (cost effective*[Text Word] OR cost-effective*[Text Word] OR “modeling”[Text Word] OR “modelling”[Text Word] OR economic model*[Text Word] OR (model*[Text Word] AND (cost*[Text Word] OR costs[Text Word] OR economic*[Text Word] OR pharmacoeconomic*[Text Word])) OR “markov model”[Title] OR “markov-model”[Title] OR “decision-analytic models” OR “cost-consequence” OR “cost consequence” OR “discrete event simulation” OR “discrete-event simulation”)AND ("2014/03/24"[Date - Entrez]: "3000"[Date - Entrez]) / 29245
#4 / (#1 AND #2 AND #3) AND ("2014/03/24"[Date - Entrez]: "3000"[Date - Entrez]) / 2

MeSH=Medical Subject Heading.

Table B-2. Cochrane Search History

Search / Query / Items Found
#1 / #1 MeSH descriptor: [Venous Thrombosis] explode all trees 2305
#2 MeSH descriptor: [Pulmonary Embolism] explode all trees 924
#3 MeSH descriptor: [Thromboembolism] explode all trees 1750
#4 MeSH descriptor: [Arthroplasty, Replacement, Knee] explode all trees 1706
#5 MeSH descriptor: [Knee Prosthesis] explode all trees 599
#6 MeSH descriptor: [Arthroplasty, Replacement, Hip] explode all trees 1619
#7 MeSH descriptor: [Hip Prosthesis] explode all trees 1053
#8 #1 or #2 or #3 or #4 or #5 or #6 or #7 7543 / 7543
#2 / #9 Apixaban or Dabigatran or Edoxaban or Rivaroxaban (Word variations have been searched) 495 / 773
#3 / #10 cost next effective* or modeling or modelling or economic next model* or "decision-analytic models" or "cost-consequence" or "cost consequence" or "discrete event simulation" or "discrete-event simulation" or model* and (cost* or economic* or pharmacoeconomic*) or "markov model" or "markov-model":ti (Word variations have been searched) 77134 / 87973
#4 / #11 #8 and #9 and #10 Publication Date from 2014 to 2015 14
Cochrane Reviews – 10 (6 imported)
Other Reviews: 1 (1 imported)
Trials: 1 (1 imported)
Economic Evaluations: 2 (1 imported) / 14

MeSH=Medical Subject Heading.

Table B-3.EconLit Search History

Search / Query / Items Found
#1 / #1 MeSH descriptor: [Venous Thrombosis] explode all trees 2305
#2 MeSH descriptor: [Pulmonary Embolism] explode all trees 924
#3 MeSH descriptor: [Thromboembolism] explode all trees 1750
#4 MeSH descriptor: [Arthroplasty, Replacement, Knee] explode all trees 1706
#5 MeSH descriptor: [Knee Prosthesis] explode all trees 599
#6 MeSH descriptor: [Arthroplasty, Replacement, Hip] explode all trees 1619
#7 MeSH descriptor: [Hip Prosthesis] explode all trees 1053
#8 #1 or #2 or #3 or #4 or #5 or #6 or #7 7543 / 7543
#2 / #9 Apixaban or Dabigatran or Edoxaban or Rivaroxaban(Word variations have been searched) 495 / 773
#3 / #10 cost next effective* or modeling or modelling or economic next model* or "decision-analytic models" or "cost-consequence" or "cost consequence" or "discrete event simulation" or "discrete-event simulation" or model* and (cost* or economic* or pharmacoeconomic*) or "markov model" or "markov-model":ti (Word variations have been searched) 77134 / 87973
#4 / #11 #8 and #9 and #10 Publication Date from 2014 to 2015 14
Cochrane Reviews: 10 (6 imported)
Other Reviews: 1 (1 imported)
Trials: 1 (1 imported)
Economic Evaluations: 2 (1 imported) / 14

MeSH=Medical Subject Heading.

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