11

Samuel N Heyman M.D. Jan 2014

LIST OF PUBLICATIONS

ARTICLES

1. Shalev O, Heyman S, Hod G, Adato R. Chronic granulocytic leukemia in pregnancy: A case report and review of the literature. Acta Obstet Gynecol Scand, 59:563-565, 1980.

2. Heyman S, Shalev O, Menczel J. The treatment of Paget's disease. Harefuah 99:438-439, 1980. (Hebrew)

3. Heyman SN, Tobi M, Shalev O. Megaloblastic anemia in vegans. Harefuah 103:148-150, 1982. (Hebrew)

4. Eliakim R, Heyman S, Korenberg A. Autoimmune thrombocytopenic purpura associated with celiac disease and keratoconjunctivitis sicca. Arch Intern Med 142;1037, 1982.

5. Heyman S, Leor R, Halperin Y. Tetanus from machwa wounds. Harefuah 105:63-65, 1983. (Hebrew)

6. Michaeli J, Mogle P, Perlberg S, Heyman S, Caine M. Emphysematous pyelonephritis. J Urology 131:203-208, 1984.

7. Heyman SN, Michaeli J, Brezis M, Gozlan L, Lernau O. Primary hyperparathyroidism presenting as cervical myelopathy. Am J Med Sci 291:112-114, 1986.

8. Brezis M, Heyman SN. Diversity of injuries in renal ischemia. Intern J Artificial Organs 9:7-8, 1986.

9. Heyman SN, Brezis M. Renal medullary hypoxia; Physiological and pathophysiological implications. Harefuah 110:31-33, 1986. (Hebrew)

10. Heyman SN, Brezis M, Stessman J. Water and salt imbalance in the elderly. Harefuah 111:245-248, 1986. (Hebrew)

11. Heyman SN, Stalnikovitch R, Heyman A, Gilon D, Mogle P. Erythromycin-induced dynamic ileus? J Clin Gastroenterol 10:551-554, 1988.

12. Heyman SN, Brezis M, Reubinoff CA, Greenfeld Z, Lechene C, Epstein F, Rosen S. Acute renal failure with selective medullary injury in the rat. J Clin Invest 82:401-412, 1988.

13. Heyman SN, Heyman A, Halperin I. Diabetogenic effect of nifedipine. DICP 23:236-237, 1989.

14. Heyman SN, Brezis M, Perlberg S, Metzner Y. Bilateral hydronephrosis and erythrocytosis. Harefuah 117:358-360, 1989. (Hebrew)

15. Heyman SN, Brezis M, Greenfeld Z, Rosen S. Protective role of furosemide and saline in radiocontrast-induced acute renal failure in the rat. Am J Kidney Dis 14:377-385, 1989.

16. Heyman SN, Fink R, Benbassat Y. The emergency room as a setting for clinical training. Harefuah 119:141, 1990.(Hebrew)

17. Brezis M, Greenfeld Z, Herman M, Meyer JJ, Heyman SN, Rosen S. Experimental nephrotoxicity of the radiocontrast agents iohexol ioxagglate and iothalamate. An in vivo and in vitro study. Invest Radiol 26:325-331, 1991.

18. Heyman SN, Mevorach D, Ghanem J. Hypertensive crisis from chronic intoxication with nasal decongestant and cough medications. DICP 25:1068-1070, 1991.

19. Brezis M, Heyman SN, Dinour D, Epstein FH, Rosen S. Role of nitric oxide in renal medullary oxygen balance. Studies in isolated and intact rat kidneys. J Clin Invest 88:390-395, 1991.

20. Heyman SN, Brezis M, Epstein FH, Spokes K, Silva P, Rosen S. Early renal medullary hypoxic injury from radiocontrast and indomethacin. Kidney Int 40:632-642, 1991.

21. Heyman SN, Rosen S, Silva P, Spokes K, Egorin MJ, Epstein FH. Protective action of glycine in cisplatin nephrotoxicity. Kidney Int 40:273-279, 1991.

22. Heyman SN, Mammen M. Effect of indomethacin and salt depletion on renal proton MR imaging. An experimental study in the rat. Acta Radiol 32:524-525, 1991.

23. Heyman SN, Clark BA, Kaiser N, Spokes K, Rosen S, Brezis M, Epstein FH. Radiocontrast agents induce endothelin release in vivo and in vitro. J Am Soc Nephrol 3:58-65, 1992.

24. Heyman SN, Brezis M, Epstein FH, Spokes K, Rosen S. Effect of glycine and hypertrophy on renal outer medullary hypoxic injury in ischemia reflow and contrast nephropathy. Am J Kid Dis 19:578-586, 1992.

25. Heyman SN, Clark BA, Kaiser N, Epstein FH, Spokes K, Rosen S, Brezis M. In-vivo and in-vitro studies on the effect of amphotericin B on endothelin release. J Antimicrob Chemotherap 29:69-77, 1992.

26. Heyman SN, Spokes K, Rosen S, Epstein FH. Mechanism of glycine protection in hypoxic injury: analogies with glycine receptor. Kidney Int 42:41-45, 1992.

27. Stillman IE, Brezis M, Greenfeld Z, Ransil BJ, Heyman SN, Rosen S. Cyclosporine nephropathy: Morphometric analysis of the medullary thick limb. Am J Kid Dis 10:162-167, 1992.

28. Weinstein JM, Heyman SN, Brezis M. Potential deleterious effect of furosemide in radiocontrast nephropathy. Nephron 62:413-415, 1992.

29. Heyman SN, Epstein FH. Glycine and cytopreservation: disappointments and promises. J Lab Clin Med 121:199-200, 1993.

30. Heyman SN, Clark BA, Kaiser N, Cantley L, Spokes K, Rosen S, Brezis M, Epstein FH. Effects of ioversol vs iothalamate on endothelin release and radiocontrast nephropathy. Invest Radiol 28:313-318, 1993.

31. Heyman SN, Eilam O, Dinour D. The osmolar gap as a diagnostic tool in severe alcohol intoxication. Harefuah 124:408-410, 1993. (Hebrew)

32. Heyman SN, Spokes K, Egorin MJ, Epstein FH. Glycine reduces early renal parenchymal uptake of cisplatin. Kidney Int 43:1226-1228, 1993.

33. Heyman SN, Stillman LE, Brezis M, Epstein FH, Spokes K, Rosen S. Chronic amphotericin nephropathy: morphometric, electron microscopic and functional studies. J Am Soc Nephrol 4:69-80, 1993.

34. Brezis M, Heyman SN, Sugar AM. Reduced amphotericin toxicity in albumin vehicle. J Drug Targeting 1:185-9, 1993.

35. Heyman SN, Rosen S, Brezis M. Radiocontrast nephropathy: A paradigm for the synergism between toxic and hypoxic insults in the kidney. Exp Nephrol 2:153-157, 1994.

36. Stillman LE, Brezis M, Heyman SN, Epstein FH, Spokes K, Rosen S. Effects of salt depletion on the kidney: changes in medullary oxygenation and thick ascending limb size. J Am Soc Nephrol 4:1538-1545, 1994.

37. Heyman SN, Rosen S, Epstein FH, Spokes K, Brezis M. Loop diuretics reduce hypoxic damage to proximal tubules of the isolated perfused rat kidney. Kidney Int 45:981-985, 1994.

38. Heyman SN, Agmon Y, Brezis M. Radiologic contrast agents and hypoxic renal medullary injury. Harefuah 127:176-179, 1994. (hebrew)

39. Brezis M, Heyman SN, Epstein F. Determinants of intrarenal oxygenation: 2. Hemodynamic effects. Am J Physiol 267 (Renal Fluid Electrolyte Physiol 36):F1063-F1068, 1994.

40. Mevorach D, Heyman SN. Pain in the marriage. A clinical problem solving. N Engl J Med 332:48-51, 1995.

41. Heyman SN, Adler S, Stewart B, Aviad I. Benign retropneumoperitoneum induced by emesis. J Clin Gastroenterol 20:88-90, 1995.

42. Heyman SN, Brezis M. Acute renal failure in glomerular bleeding. A puzzling phenomenon. Nephrol Dial Transplant 10:591-593, 1995.

43. Heyman SN, Kaminski N, Brezis M. Dopamine increases medullary blood flow without improving regional hypoxia. Exp Nephrol 3:331-337, 1995.

44. Heyman SN, Babayof I. Emphysematous complications in dentistry, 1960-1993: an illustrative case report and review of the literature. Quintessence Int 26:535-543, 1995.

45. Heyman SN, Fuchs S, Brezis M. The role of medullary ischemia in acute renal failure. New Horizons 3:597-607, 1995.

46. Heyman SN, Rosen S, Fuchs S, Epstein FH, Brezis M. Myoglobinuric acute renal failure in the rat: A role for medullary hypoperfusion, hypoxia and tubular obstruction. J Am Soc Nephrol 7:1066-1074, 1996.

47. Heyman SN, Fuchs S. Yafe R, Beeri R, Elazarian L, Brezis M, Rosen S. Renal microcirculation and tissue damage during acute ureteral obstruction: the effect of saline infusion, indomethacin and radiocontrast. Kidney Int 51:653-63, 1997.

48. Heyman SN, Greenbaum R, Shina A, Rosen S, Brezis M. Myoglobinuric acute renal failure in the rat: a role for acidosis? Exp Nephrol 5:210-16, 1997.

49. Fuchs S, Yaffe R, Beeri R, Rosen S, Heyman SN, Brezis M. Failure of insulin-like growth factor 1 to improve radiocontrast nephropathy. Exp Nephrol 5:88-94, 1997.

50. Heyman SN, Karmeli F, Rachmilewitz D, Haj Yehia A, Brezis M. Intrarenal nitric oxide monitoring with a clark-type electrode: potential pitfalls. Kidney Int 51:1619-23, 1997.

51. Heyman SN, Karmeli F, Brezis M, Rachmilewitz D. The effect of ketotifen on nitric oxide synthase activity. Br J Pharmacol 120:1545-1551, 1997.

52. Heyman SN, Ginosar Y, Shapiro M, Kluger Y, Marx N, Maayan S. Diarrheal epidemics among Rwandan refugees, 1994: management and outcome in a field hospital. J Clin Gastroenterol 25:595-601, 1997.

53. Heyman SN, Rosen S, Brezis M. The renal medulla: Life at the edge of anoxia. Blood Purif 15:232-242, 1997.

54. Heyman SN, Eldad A, Wiener M. Airborne field hospital in disaster area: Lessons from Armenia (1988) and Rwanda (1994). Prehosp Disaster Med 13:21-28, 1998.

55. Heyman SN, Ginosar Y, Niel L, Amir J, Marx N, Shapiro M, Maayan S. Meningococcal meningitis among Rwandan refugees: diagnosis, management and outcome in a field hospital. Int J Infect Dis 2:137-142, 1998.

56. Heyman SN, Goldfarb M, Karmeli F, Shina A, Rachmilewitz D, Brezis M. The effect of radiocontrast on intra-renal nitric oxide (NO) and NO synthase activity. Exp Nephrol 6:557-562, 1998.

57. Heyman SN, Goldfarb M, Darmon D, Brezis M. Tissue oxygenation modifies nitric oxide bioavailability. Microcirculation 6:199-203, 1999.

58. Heyman SN, Reichman J, Brezis M. The pathophysiology of contrast nephropathy: a role for medullary hypoxia. Invest Radiol 34:685-691, 1999.

59. Zlatkin S, Aamar S, Specter G, Simanovsky N, Leibowitz D, Yeshurun D, Heyman SN. Takayasu’s Arteritis identified by computerized tomography: revealing the submerged portion of the iceberg? IMAJ 1:245-249, 1999.

60. Heyman SN, Rosen S, Darmon D, Goldfarb M, Bitz H, Shina A, Brezis M. Endotoxin-induced renal failure: I. a role for altered renal microcirculation. Exp Nephrol 8:266-274, 2000.

61. Heyman SN, Rosen S, Darmon D, Goldfarb M, Bitz H, Shina A, Brezis M. Endotoxin-induced renal failure: II. a role for tubular hypoxic damage. Exp Nephrol 8:275-282, 2000.

62. Bitz H, Darmon D, Goldfarb M, Shina A, Block C, Rosen S, Brezis M, Heyman SN. Transient ureteral obstruction predisposes to ascending pyelonephritis and tubulo-interstitial disease: studies in rats. Urol Res 29:67-73, 2001

63.  Reichman J, Shina A, Rosen S, Goldfarb M, Brezis M, Heyman SN. Renal effects of nabumetone: impairment of function in isolated perfused rat kidneys contrasts with preservation of renal function in vivo. Exp Nephrol 9:387-396, 2001

64.  Eliakim R, Karmeli F, Cohen P, Heyman SN, Rachmilewitz D. Dual effect of nicotine administration: augmentation of jejunitis and amelioration of colitis induced by iodoacetamide in rats. Int J Colorectal Dis 16:14-21, 2001

65.  Goldfarb M, Abassi Z, Rosen S, Shina A, Brezis M, Heyman SN. Chronic heart failure predisposes to hypoxic outer medullary tubular injury: studies in rats. Kidney Int 60:607-613, 2001

66.  Rosen S, Heyman SN. Difficulties in understanding human "acute tubular necrosis": limited data and flawed animal models. Kidney Int 60:1220-4, 2001

67.  Kassis I, Lak L, Adler J, Rinat C, Shazberg G, Fekede Tewade D, Shoshani E, Miller D, Heyman SN. Medical Relief Operation to Rural Northern Ethiopia: addressing an ongoing disaster. IMAJ 3:772-777, 2001.

68.  Heyman SN, Shina A, Brezis M, Rosen S. Proximal tubular injury attenuates outer medullary hypoxic damage. Studies in the isolated perfused kidney. Exp Nephrol 10:259-266, 2002

69.  Heyman SN, Specter G, Aamar S, Rubinger D, Pappo O, Ackerman Z. Systemic Lupus Erythematosus associated with Autoimmune Cholangiopathy. Liver 22:102-106, 2002

70.  Heyman SN, Marmor S, Ben-Abraham R, Shani Y, Heled Y, Shapira B, Lifschitz-Mercer B, Amital H. Multi-Organ Failure in a Young Soldier, a clinical-pathological meeting. Harefuah 141:204-209, 2002

71.  Heyman SN, Lieberthal W, Rogiers P, Bonventre JV, Animal Models of Acute Tubular Necrosis. Curr Op Crit Care 8:526-534, 2002

72.  Heyman SN, Goldfarb M, Shina A, Karmeli F, Rosen S. N-acetylcysteine (NAC) ameliorates renal microcirculation: studies in rats. Kidney Int 63:634-641, 2003

73.  Heyman SN, Rosen S. Dye induced nephropathy. Semin Nephrol 23:477-485, 2003

74.  Darmon D, Goldfarb M, Shina A, Rosen S, Heyman SN. The effect of poly-(ADP-ribose) polymerase (PARP) inhibition on outer medullary hypoxic damage. Nephron Physiol 95:1-9, 2003

75.  Nassar T, Akkawi S, Shina A, Haj-Yehia A, Bdeir K, Tarshis M, Heyman SN, Higazi AAR. The in vitro and in vivo effect of tPA and PAI-1 on blood vessel tone. Blood 103:897-902, 2004

76.  Heyman SN, Rosenberger C, Rosen S. Erythropoietin – a potential remedy for renal tubular injury? Kidney Int 65:737-738, 2004

77.  Heyman SN, Shina A, Zohair H, Goldfarb M, Rosen S, Higazi AA. The Fibrinolytic System Attenuates Vascular Tone: Effects of Tissue Plasminogen Activator (tPA) and Aminocaproic Acid on Renal Microcirculation. Br J Pharmacol 141:971-978, 2004

78.  Bellomo R, Ronco C, Kellum JA, Mehta RL, Palevsky P and the ADQI workgroup (including Heyman SN). Acute renal failure: definition, outcome measures, animal models, fluid therapy and information technology needs. The Second International Consensus Conference of the Acute Dialysis Quality Initiative(ADQI) Group. Critical Care 8:R204-R212, 2004

79.  Korem M, Ackerman Z, Sciaki-Tamir Y, Gino G, Salameh-Giryes S, Perlberg S, Heyman SN. Post-partum acute kidney failure and hyponatremia - A clinical quiz. IMAJ 6:639-641, 2004

80.  Francis BN, Abassi Z, Heyman SN, Winaver J, Hoffman A. Differential regulation of ETA and ETB in the renal tissue of rats with compensated and decompensated heart Failure. J Cardiovasc Pharmacol 44 (Suppl 1):S362-S365, 2004

81.  Rosenberger C, Heyman SN, Rosen S, Shina A, Gruber G, Goldfarb M, Griethe W, Frei U, Bachmann S, and Eckardt KU. Upregulation of HIF in acute renal failure – evidence for a protective transcriptional response to hypoxia. Kidney Int 67:531-542, 2005

82.  Heyman SN, Rosenberger C, Rosen S. Regional alterations in renal hemodynamics and oxygenation: a role in radiocontrast nephropathy. Nephrol Dial Transpl 20 (Suppl 1):i6-i11, 2005

83.  Heyman SN, Goldfarb M, Rosenberger C, Shina A, Rosen S. The Effect of nicotine on the renal microcirculation in anesthetized rats: a potential for medullary hypoxic injury? Am J Nephrol 25:226-232, 2005

84.  American Society of Nephrology Renal Research Report. J Am Soc Nephrol 16:1886-1903, 2005 (Heyman SN, participant)

85.  Benbassat J, Baumal R, Heyman SN, Brezis M. Need for a paradigm shift in teaching basic clinical skills to medical students: the reflective clinical examination. Acad Med 80:1121-1126, 2005

86.  Rosenberger C, Rosen S, Heyman S. Current understanding of HIF in renal disease. Kidney and Blood Pressure Research 28:325-340, 2005

87.  Damianovich M, Ziv I, Heyman SN, Rosen S, Shina A, Kidron D, Aloya T, Grimberg H, Levin G, Reshef A, Bentolila A, Cohen A, Shirvan A. ApoSense: A Novel Technology for Imaging of Cell Death in Acute Renal Tubular Necrosis Eur J Nucl Med Mol Im 33:281-291, 2006

88.  Maril N, Margalit R, Rosen S, Heyman SN, Degani H. Detection of Evolving Acute Tubular Necrosis with Renal 23Sodium MRI: Studies in Rats. Kidney Int 69:765-8, 2006

89.  Goldfarb M, Rosenberger C, Abassi Z, Shina A, Zilbersat F, Eckhardt KU, Rosen S, Heyman SN. Acute-on-chronic renal failure in the rat: Functional compensation and hypoxia tolerance. Am J Nephrol 26:22-33, 2006