Supplementary table S2: Contents of the MLPA P078-C1 Breast tumor kit

Gene / Chr / probes (N) / Detection exons / Gene Description
ESR1 / 6q25.1 / 2 / 10, 11 / estrogen receptor 1
EGFR / 7p12 / 2 / 8, 25 / epidermal growth factor receptor
ZNF703 / 8p11.23 / 2 / 1, 2 / zinc finger protein 703
FGFR1 / 8p12 / 2 / 4, 17 / fibroblast growth factor receptor 1
ADAM9 / 8p11.22 / 1 / 6 / ADAM metallopeptidase domain 9
IKBKB / 8p11.2 / 2 / 10, 20 / inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
PRDM14 / 8q13.3 / 1 / 7 / PR domain containing 14
MTDH / 8q22.1 / 2 / 2, 8 / metadherin
MYC / 8q24.21 / 2 / 1, 3 / v-myc avian myelocytomatosis viral oncogene homolog
CCND1 / 11q13 / 2 / 3, 5 / cyclin D1
EMSY / 11q13.5 / 2 / 10, 16 / chromosome 11 open reading frame 30
CDH1 / 16q22.1 / 2 / 1, 9 / cadherin 1, type 1, E-cadherin (epithelial)
CPD / 17q11.2 / 1 / 12 / carboxypeptidase D
MED1 / 17q12 / 1 / 9 / mediator complex subunit 1
HER2 / 17q12 / 4 / 7, 13, 19, 28 / v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
CDC6 / 17q21.3 / 1 / 2 / cell division cycle 6
TOP2A / 17q21-q22 / 3 / 11, 14, 20 / topoisomerase (DNA) II alpha 170kDa
MAPT / 17q21.1 / 1 / 8 / microtubule-associated protein tau
PPM1D / 17q23.2 / 1 / 2 / protein phosphatase, Mg2+/Mn2+ dependent, 1D
BIRC5 / 17q25 / 3 / 1, 2, 4 / baculoviral IAP repeat containing 5
CCNE1 / 19q12 / 2 / 6, 11 / cyclin E1
AURKA / 20q13 / 2 / 7, 9 / aurora kinase A

Chr : chromosomal location ; probes: the number of probes in the P078 breast tumor MLPA kit ; detection exon: the exon that each probe detects