SUMMARY OF CRA EXPERIENCE

overview

¨  Average of 15 years (range: 8 – 21 years) field monitoring experience

¨  Extensive training and experience resulting from prior monitoring and management roles at pharmaceutical, biotechnology, medical device, diagnostics, and/or clinical research organizations

¨  Established, reliable consultants with a strong commitment to quality

¨  Several of our consultants also have backgrounds as:

–  Clinical research managers and/or coordinators in a healthcare setting

–  Good clinical practices (GCP) auditors

service capabilities

¨  Study site monitoring (pre-study evaluation, study initiation, treatment observation, routine monitoring, study close-out)

¨  Study coordinator support (CRF/DRF completion, document management)

¨  Study site GCP auditing

therapeutic area/indication experience

CARDIOVASCULAR / CNS/NEUROLOGY
·  Angina / ·  Generalized Anxiety Disorder
·  Anticoagulant Therapy / ·  Alzheimer’s Disease
·  Arrhythmia Control / ·  Attention Deficit Hyperactivity Disorder
·  Arterial Stenosis / ·  Bipolar Disorder
·  Atrial Fibrillation / ·  Depression
·  Cardiac Stents / ·  Epilepsy
·  Congestive Heart Failure / ·  Migraine
·  Coronary Artery Disease / ·  Obsessive Compulsive Disorder
·  Hypercholesterolemia / ·  Panic Disorder
·  Hyperlipidemia / ·  Parkinson’s Disease
·  Deep Vein Thrombosis / ·  Schizophrenia
·  Hypertension / ·  Sleep Apnea
·  Myocardial Infarction / ·  Smoking Cessation
·  Social Anxiety Disorder
·  Stroke

PROMETRIKA, LLC ¨ 725 Concord Avenue ¨ Cambridge, MA 02138

Phone: 617-868-2020 ¨ Fax: 617-868-2122

SUMMARY OF CRA EXPERIENCE (p. 2)

DERMATOLOGY / ENDOCRINOLOGY
·  Acne Vulgaris / ·  AIDS-Associated Catabolism/Wasting
·  Actinic Keratosis / ·  Diabetes Mellitus
·  Atopic Dermatitis / ·  Hormone Replacement
·  Psoriasis / ·  Hypogonadism
·  Rosacea / ·  Obesity
·  Seborrheic Dermatitis / ·  Thyroid Disorder
·  Tinea Pedis / ·  Xerostomia
GASTROENTEROLOGY / INFECTIOUS DISEASE
·  Acid Reflux Disease / ·  Cryptococcal Meningitis
·  Crohn’s Disease / ·  Fungal Infections
·  C. difficile-Associated Diarrhea / ·  Hepatitis C
·  Irritable Bowel Syndrome / ·  HIV/AIDS
·  Peptic Ulcer Disease / ·  Neoplastic Meningitis
·  Ulcerative Colitis / ·  Nosocomial Pneumonia
·  Otitis (Externa, Media)
ONCOLOGY / ·  Sinusitis
·  Acute Myeloid Leukemia / ·  Urinary Tract Infection
·  Breast
·  Bronchioloalveolar Carcinoma / OPHTHALMOLOGY
·  Colon/Colorectal / ·  Blepharitis
·  Glioblastoma Multiforme / ·  CMV Retinitis
·  Head & Neck Carcinoma / ·  Conjunctivitis
·  Kaposi’s Sarcoma / ·  Diabetic Macular Edema
·  Leptomeningeal Disease / ·  Uveitis
·  Lung
·  Lymphoma / RESPIRATORY
·  Melanoma / ·  Allergic Rhinitis
·  Multiple Myeloma / ·  Asthma
·  Myelodysplastic Syndrome / ·  Acute Respiratory Distress Syndrome
·  Non-small Cell Lung / ·  Bronchitis (Acute, Chronic)
·  Ovarian / ·  Chronic Obstructive Pulmonary Disease
·  Primary Peritoneal Carcinoma / ·  Seasonal Allergies
·  Prostate
·  Pancreatic / UROLOGY
·  Renal Carcinoma / ·  Acute Urinary Retention
·  Soft Tissue Sarcoma / ·  Benign Prostatic Hypertrophy
·  Erectile Dysfunction
·  Overactive Bladder
·  Urinary Incontinence

PROMETRIKA, LLC ¨ 725 Concord Avenue ¨ Cambridge, MA 02138

Phone: 617-868-2020 ¨ Fax: 617-868-2122