CURRICULUM VITAE
(updated January 9, 2018)
J. David Puett, Ph.D.
CURRENT ACADEMIC APPOINTMENTS AND CONTACT INFORMATION
Regents Professor and Department Head Emeritus
Department of Biochemistry and Molecular Biology
The University of Georgia
Athens, Georgia 30602
Adjunct Professor
Department of Biochemistry and Biophysics
The University of North Carolina at Chapel Hill School of Medicine
Chapel Hill, North Carolina 27599
Email <>
EDUCATION
1969Ph.D. in Biochemistry, University of North Carolina at Chapel Hill, NC
1965M.S. in Physics, University of North Carolina at Chapel Hill, NC
1961B.S. in Physics, North Carolina State University, Raleigh, NC
ACADEMIC APPOINTMENTS
2013-present Adjunct Professor of Biochemistry and Biophysics, University of North Carolina School of Medicine, Chapel Hill, NC
2010-present Regents Professor and Department Head Emeritus, Department of Biochemistry and
Molecular Biology,University of Georgia, Athens, GA (August 1, 2010)
2001-2010 Regents Professor, Department of Biochemistry & Molecular Biology, University of
Georgia, Athens, GA
1993-2001 Professor, Department of Biochemistry & Molecular Biology, University of Georgia,
Athens, GA
1993-2006 Head, Department of Biochemistry & Molecular Biology, University of Georgia,
Athens, GA
1993-1995 Adjunct Professor of Biochemistry and Molecular Biology, University of
Miami School of Medicine, Miami, FL
1983–1993 Director, The Reproductive Sciences and Endocrinology Laboratories, University of
Miami School of Medicine, Miami, FL (primary appointment)
1983-1993 Professor of Biochemistry and Molecular Biology, University of Miami School of
Medicine, Miami, FL (primary appointment)
1983-1993 Professor of Medicine and of Obstetrics and Gynecology, University of Miami School
of Medicine, Miami, FL (secondary appointments)
1983-1986 Adjunct Professor of Biochemistry, Vanderbilt University School of Medicine,
Nashville, TN
1979-1983 Professor of Biochemistry, Vanderbilt University School of Medicine, Nashville,TN
1974-1979 Associate Professor of Biochemistry, Vanderbilt University School of Medicine,
Nashville, TN
1969-1974 Assistant Professor of Biochemistry, Vanderbilt University School of Medicine,
Nashville, TN
OTHER RELEVANT PROFESSIONAL APPOINTMENTS AND EMPLOYMENT
2006 Member of the Athens Regional Medical Center Institutional Review Board
2005-2010 Member of the Center for Drug Discovery Executive Committee
2005-2006 President of the Association of Medical & Graduate Departments of Biochemistry
2005 Coordinator of the International Conference on Gonadotropins & Receptors,
University of Georgia
2004-2005 President-Elect of the Association of Medical and Graduate Departments of
Biochemistry
2004-2012 Member of the Athens Regional Medical Center Oncology Committee
2000-2003 Coordinator of the University of Georgia’s Cancer Initiative and Partnership with
MCG and the Athens medical community.
2000-2002 Chair of the Education Committee and Member of the Board of Directors, Association
of Medical and Graduate Departments of Biochemistry
2000-2001 Honors Program Faculty Mentor, University of Georgia
2000-2007 Advisory Board Member of the Center for Undergraduate Research Opportunities,
University of Georgia
1999-2003 Senior Foundation Fellow, University of Georgia (Emeritus: 2003-2010)
1999 Visiting Professor at Benedict College, Columbia, SC, sponsored by the Endocrine
Society
1995-1996 Advisory Board, Georgia Biotechnology Center, Georgia Research Alliance
1993-1996 Advisory Board, The Vanderbilt University Center for Reproductive Biology
Research
1993 Bohan Visiting Professor, University of Kansas
1990 Consultant to the World Health Organization to Evaluate Institutes in Shanghai and
Beijing
1990 Visiting Professor in the Glycoprotein Hormone Course, University of Michigan, Ann
Arbor
1989-1991 National Scientific Advisory Board of the Women's Research Institute, University of
Kansas, Wichita, KS
1988 Society of Tokyo Women's Medical College, Visiting Professor
1988 Visiting Professor, Zhejiang Medical University, China
1985-1993 Program Leader, The University of Miami Comprehensive Cancer Center
1985-1990 Scientific Advisory Board of the Cancer Research Council, Bethesda, MD
1984-1993 Program Director, The Reproductive Biology Training Program, University of Miami,
FL
1984-1993 Member, Comprehensive Cancer Center, University of Miami, FL
1980-1983 Medical Advisory Board, National Hormone and Pituitary Program
1977-1979 Director of Graduate Studies, Department of Biochemistry, Vanderbilt University
1975-1983 Program Director, Vanderbilt Population Training Program
1975-1983 Member of the Vanderbilt Cancer Center
1975-1976 Vice-Chairman, Vanderbilt Graduate Faculty Council
1974-1976 Member, Exec. Comm. of the Vanderbilt Graduate Faculty Council
1973-1983 Associate Director and Member, Vanderbilt Population Center
1973-1976 Member, Vanderbilt Graduate Faculty Council
1962-1967 Research Associate, Basic Research Department, Chemstrand Research Center, Inc.
(Monsanto subsidiary), Research Triangle Park, NC
1961-1962 Research Scientist, Bancroft Co., Wilmington, DE
NATIONAL INSTITUTES OF HEALTH STUDY SECTION APPOINTMENTS
1991-1993 Chairperson, Biochemical Endocrinology Study Section (Member, 1990-1993)
1979-1982 Biochemical Endocrinology Study Section Member
1977-1979 Reproductive Biology Study Section (AHR) ad hoc Member
Also Invited speaker to several workshops supported by NICHHD; invited to assist in writing RFP for NIH rat pituitary hormone program; invited to review applications for several NIH contracts; member of numerous NIH site visit teams and ad hoc Member of several Study Sections
AMERICAN CANCER SOCIETY REVIEW PANEL APPOINTMENT
1994-1997 Tumor Biochemistry and Endocrinology Study Section
ADDITIONAL GRANT REVIEW ACTIVITIES
In addition to regular and ad hoc memberships on NIH Study Sections and the American Cancer Society Tumor Biochemistry and Endocrinology Review Panel, Dr. Puett regularly reviewed grants for the National Science Foundation, the U.S. Department of Agriculture, and funding agencies in Israel and Poland.
EDITORIAL BOARD APPOINTMENTS
2011-present Editorial Advisory Board, Annual Review and Research in Biology
2010-present Editorial Board, Biomolecules(MDPI)
2010-present Editorial Board (Honorary), Journal of Receptor, Ligand and Channel Research
2003-2006 Editorial Board, Endocrine Reviews
2003-2008 Editorial Board, Molecular Endocrinology
2003-2006 Editorial Advisory Board, Current Trends in Endocrinology
1996-1999 Editorial Board, Endocrinology
1993-2010 Editorial Board, Endocrine
1983-1986 Editorial Board, Journal of Andrology
1982-1987 Editorial Board, Journal of Biological Chemistry
Also reviewer of manuscripts for Biochemistry, Molecular Endocrinology, Endocrinology, Journal of Biological Chemistry, The FASEB Journal, International Journal of Peptide and Protein Research, Molecular and Cellular Endocrinology, Chemical Reviews, Archives of Biochemistry and Biophysics, Journal of Clinical Endocrinology and Metabolism, Proceedings of the National Academy of Sciences, Endocrine Reviews, Journal of Andrology, Science, Gene, Journal of Molecular Endocrinology, Biopolymers, and BioEssays. Consultant (ad hoc) to Oxford University Press and CRC Press, Inc.
HONORS AND AWARDS
2007 Joy Goodwin Lecturer, Auburn University
2005 Honorary Professor, Jilin University, Changchun, China
2005 Neena B. Schwartz Lectureship in Reproductive Science, Northwestern University
2004 Catalyst Award, The Georgia Research Alliance
2001 Regents Professor, University of Georgia
1992 John M. Marsh Memorial Lecturer, University of Miami
1992 Omicron Delta Kappa (National Leadership Honor Society), University of Miami
1991 Phi Beta Delta (Honor Society for International Scholars), University of Miami
1990 Robert B. Greenblatt Lecturer, Medical College of Georgia, Augusta
1986 George Paff Award for Teaching Excellence, University of Miami School of Medicine
1984 Commissioned by the United Nations Fund for Population Activities to edit a book entitled
"Human Fertility, Health and Food. Impact of Molecular Biology and Biotechnology" for the 1984 International Conference on Population, Mexico City
1975 Research Career Development Awardee (NIH)
1971 Camille and Henry Dreyfus Teacher-Scholar Awardee (Dreyfus Foundation)
PROFESSIONAL AND LEARNED SOCIETIES(Member: Past and Present)
American Association for the Advancement of Science, American Association for Cancer Research, American Chemical Society, American Society for Biochemistry & Molecular Biology, Endocrine Society, Protein Society, Society for Ethnobiology, Society for the Study of Reproduction, The Renaissance Society
TEACHING RESPONSIBILITIES
At the University of Georgia Dr. Puett participated in several undergraduate and graduate courses, including service as course organizer and lead instructor for human biochemistry and disease, biology for medicine, and Florence and the Italian Renaissance. He also lectured first-year medical students at the Georgia Regents University/University of Georgia School of Medicine. At the University of Miami he participated in undergraduate, graduate, and medical student teaching. Topics in physical biochemistry, metabolism, and endocrinology were presented to undergraduate and graduate students; an integrated endocrinology course was developed and coordinated for first-year medical students. At Vanderbilt University he taught a course for graduate students in physical chemistry of biopolymers and presented lectures in endocrinology and neuroendocrinology to first-year medical and graduate students;he also taught in the biochemistry laboratory sections. Dr. Puett directed the Ph.D. dissertations of 26 students and the M.S. theses of seven students, has mentored nearly 30 postdoctoral fellows and visiting scientists, and has served on the Continuing Committees of numerous Ph.D. students in various departments at Vanderbilt University, the University of Miami, and the University of Georgia.
Courses taught during the past several years:
BCMB 4120/6120, Human Biochemistry and Disease, Fall (enrolled over 130 students in most
recent offering)
BCMB/GENE, Biology for Medicine, each Maymester (with Dr. Anderson; enrolled 30-35 students)
HONS1990H, Renaissance Florence (Honors seminar (capped at 15 students)
Medical School (first-year) lectures on endocrinology (40 students)
FRES 1010, Florence, Epicenter of the Italian Renaissance (capped at 15 students)
FRES 1010, The Language of Reproduction: Hormones as Messengers (capped at 15 students)
FRES 1010, The Language of Human Reproductive Endocrinology (capped at 15 students)
Guest lecturer in BCMB 4200/6200, Biotechnology; BIOL 2990H, Honors Seminar; GENE 3200H section, GENE Senior Seminar, and Endocrinology section for first-year medical students (GRU/UGA).
OTHER ACTIVITIES
Testified before the House Committee on Appropriations, Subcommittee, Departments of Labor and HEW, supporting appropriation for the Center for Population Research, NICHHD (4/25/79).
Program Chairman of the 1986 Miami Winter Symposium on Advances in Gene Technology: Molecular Biology of the Endocrine System, Miami, FL (1/86).
Co-organizer of a satellite symposium of the American Society of Cell Biology Meeting on Hormones, Cell Biology and Cancer, Washington, D.C. (12/86).
Organizing Committee of the 1987 International Aromatase Conference, Miami, FL (3/87).
Editor of the newsletter, The REPSCEND Reporter.
Organizer of the W.J. LeMaire Symposium on Reproductive Endocrinology, Miami, FL (12/88) and Editor of the Proceedings (Steroids54, November and December issues, 1989).
Appearances on local (Miami channels 6 and 10) and national television (CNN).
Co-Organizer of the Serono Symposium on Glycoprotein Hormones: Structure, Function and
Clinical Implications, Santa Barbara, CA (3/93).
Program Committee Member of the Society for the Study of Reproduction Annual Meeting (2002- 2004).
RECENT FUNDING (J.D. Puett, PI)
1. NIH RO1 DK33973, hCG LH/CG Receptor Binding and Activation,” (approved through 4/30/10).[N.B. This grant was initially awarded to Dr. Puett at Vanderbilt University in 1972; it was then transferred to the University of Miami in 1983 and then to the University of Georgia in 1993.] Supplement awarded to DK33973 for research on human embryonic stem cells (7/10/03 - 4/30/04), direct costs: $75,000. Terminal fiscal year direct costs: $329,820.
2. NIH RO1 DK69711, “Binding Determinants of Glycoprotein Hormone Receptors,” 2005-2008 (no-cost extension approved through 12/31/11). Terminal fiscal year direct costs: $293,882.
3. Earlier funding included NIH R01s from NCI and GMS, two T32 Training grants, the Camille and Henry Dreyfus Foundation, and private funding from Smith-Kline.
PATENTS
1. D. Puett, L.S. Kelly, and J.M. Pierce, “Lectin-Based Immunoassay for the Detection of hCG-Related Cancers,”U.S. Provisional Patent Application No. 60/370, 589 (2008).
2. J. Cui, F. Li, D. Puett, and Y. Xu, ``Protein Markers Identification for Gastric Cancer Diagnosis,`` U.S. Provisional Patent Application (2010).
3. J. Cui, F. Li, D. Puett, and Y. Xu, ``Methods and Systems for Predicting Proteins that can be Secreted into Bodily Fluids`` (2009).
TRAINING RECORD
Ph.D. Students
and Current Position
(if known) Dissertation Title (Year)
Mario Ascoli, Ph.D. Metabolic Fate of Luteinizing Hormone (1975)
Professor
Dept. Pharmacology
Univ. of Iowa
Iowa City, IA
Lenore Kelly, Ph.D. Purification and Characterization of
Agilent Technologies Pituitary-derived Growth Factors (1978)
San Francisco, CA
R. Glenn Hammonds, Jr., Ph.D. Structure and Function of Beta-Endorphin (1979)
Research Scientist,Tularik
South San Francisco, CA
Deborah L. Segaloff, Ph.D. Characterization of the Desensitized State of
Professor Perifused Leydig Tumor Cells (1980)
Dept. of Physiology & Biophys.
Univ. of Iowa
Iowa City, IA
Thomas W. Strickland, Ph.D. Contribution of Subunits to Glycoprotein
Research Scientist Hormone Function: A Study Utilizing
AMGEN, Inc. Hybrids (1981)
Thousand Oaks, CA
James L. Jones, M.D., Ph.D. Synthesis of Phenothiazines with Specific
Univ. of Florida Reporter Groups for Magnetic Resonance
Jacksonville, FL Spectroscopy with Applications to
1
Calmodulin and Serum Albumin (1981)
Paula B. Hewgley, Ph.D. Characterization of Spin Labeled
Retired (Nashville, TN) Calmodulin as a Probe for Calcium
Binding (1983)
Susan Bane Hastie, Ph.D. The Mechanism of Colchicine and Analog
Professor Binding to Tubulin: Spectral, Thermodynamic
Dept. of Chemistry Equilibrium and Kinetic Properties (1983)
SUNY-Binghamton
Binghamton, NY
David P. Giedroc, Ph.D. The Interaction of Calmodulin with β-Endorphin
Professor and Chair and Derived Peptides (1984)
Dept. of Chemistry
Indiana University
Bloomington, IN
Arthur E. Jackson, Ph.D. Specific Spin Labeling of Calmodulin and
Law Office of AEJ Characterization of the Products (1985)
Stockton, NJ
Edith S. Lovegren, M.D., Ph.D. β-Endorphin and α-N-Acetyl β-Endorphin:
Internal Medicine Practice Synthesis, Conformation and Binding Parameters Denver, CO (1986)
Mark E. Brandt, Ph.D. Aromatase and Rat OvarianSteroidogenesis (1988)
Associate Prof. of Chemistry
Rose-Hulman Inst. Of Technology
Terre Haute, IN
Samer El-Deiry, M.D., Ph.D. Characterization of a Carboxy-terminal
Endocrinology Practice Deletion Mutant of the Human
Albany, New York Choriogonadotropin Beta Subunit (1989)
Frank S. Czerwiec, M.D., Ph.D. Hormonal Influences on Gene Expression:
Pharmaceutical firm Gonadotropin and Growth Factor
Bethesda, MD Control of Oncogenes (1990)
Fang Chen, Ph.D. Structure-function Relationships
Research Scientist of Human Choriogonadotropin (1991)
Univ. of Pennsylvania
Philadelphia, PA
Haiying Xia, Ph.D. Structure-function Relationships of Human
1
CEO (start-up) Chorionic Gonadotropin Using Site-directed
South San Francisco, CA Mutagenesis: Contact Sites for Holoprotein
Formation and Receptor Binding (1994)
Jianing Huang, Ph.D. Molecular Basis of the Human
Research Scientist Choriogonadotropin-Receptor
Rigel, Inc. Interaction (1995)
South San Francisco, CA
Adviye Ergul, M.D., Ph.D. Molecular Aspects of Endothelin-1 (1995)
Professor
Dept. of Physiology
Georgia Health Sci. Univ.
Augusta, GA
Lizette M. Fernandez, Ph.D. Structure-Function Relationships of the
Law Firm (intellectual property) Luteinizing Hormone/Chorionic Gonadotropin
Atlanta, GA Receptor (1995)
Chengbin Wu, Ph.D. Structural and Functional Studies of Human
CSO, Head of R&D Chorionic Gonadotropin and its Receptor
Shanghai CP Guojian through Protein Engineering (1997)
Shanghai, China
Carlos A. Alvarez, Ph.D. Structure-Function Analysis of a Conserved
Pensacola Christian College Region in the Extracellular Domain of the Rat
Pensacola, FL Luteinizing Hormone/Chorionic Gonadotropin (LH/CG) Receptor (1997)
Neil Bhowmick, Ph.D. Structure-Function Analysis of the Binding andAssociate Professor Ligand-Mediated Down-Regulation of the Dept. Medicine Lutropin and Endothelin-A Receptors (1998)
Cedars-Sinai Med. Ctr., CA
Gregory B. Fralish, Ph.D.Expression and Structural Characterization of
Program Directorthe Extracellular Binding Domain of the G-Protein
Clin. Translational Med. Res.Coupled, Luteinizing Hormone Receptor in
University of Virginia Complex with Its Ligand Choriogonadotropin Charlottsville, VA (2002)
Rebecca L. Schubert, Ph.D.Fusion Proteins Engineered to Characterize
Science TeacherGlycoprotein Hormone-Receptor Interactions
(MD)(2002)
Thomas P. Meehan, Ph.D.In vivo Consequences of the Expression of
Physicians AssistantConstitutively Active Luteinizing Hormone
Indianapolis, INReceptors (2003)
Co-mentor with Dr. Prema Narayan
Yongsheng Li Structural Aspects of the Lutropin Receptor
(deceased 03/26/2007)
Geneva DeMars GPCR-G Protein Coupling (2010)
Instructor
Armstrong Atlantic State Univ.
Savannah, GA
M.S. Students Thesis Title (Year)
and Current Position
(if known)
James D. Luketich, M.S.,M.D. Effects of Human Choriogonadotropin on
Department of SurgeryMitochondrial and Microsomal Cytochrome
University of Pittsburgh, PAP-450 Levels in Mouse Testes (1983)
Mark E. Brandt, M.S., Ph.D. Aromatase and Testosterone Metabolism in
Assoc. Prof. ChemistrySelected Steroidogenic Tissues and the
Rose-Hulman Inst. Tech. Effects of an Aromatase Inhibitor (1986)
1
Terre Hute, IN
Enrique J. Mendoza, M.S., M.D. Effects of an Aromatase Inhibitor on Rat
Dept. of Medicine Uterine Estrogen Receptors (1987)
(Endocrinology)
Panama City, Panama
Xiaodong Wu, M.S., Ph.D. Cloning a Designed, Novel Calmodulin Gene
Unknown (1989)
Hakan Bermek, M.S., Ph.D. Internalization and Degradation of [125I]
Professor Endothelin-1 by Vascular Smooth Muscle A-10 Istanbul, Turkey Cells (1995)
Leyi Shen, M.S. Structure-Function Relationships of Human
unknown Choriogonadotropin β-Subunit Using Site-
Directed Mutagenesis: On the Role of Conserved Arg-68 in Hormone Secretion (1995)
Margaret Shirley, M.S., M.D. Characterization of Trophoblast-like Cells Derived
University of California, SF from Human Embryonic Stem Cells (2005)
San Francesco, CA
Hope Blackstone (M.S.)Differentiation of Human Embryonic Stem Cells Co-mentor with Dr. Stephen Dalton
Fred Hutchinson
Seattle, WA
Postdoctoral FellowsYearsCurrent Position
Leslie A. Holladay, Ph.D.1972-75Retired (TN)
Mario Ascoli, Ph.D.1977-78Professor
Dept. Pharmacology
Univ. of Iowa
Iowa City, IA
Thomas D. Noland, Ph.D.1979-81Unknown
Michael H. Melner, Ph.D.1980-83Program Director
American Cancer Society
Atlanta, GA
Stephen J. Zimniski, Ph.D.1981-84Associate Professor
1
Dept. of Biology
West Chester Univ.
West Chester, PA
Razia H. Ahmed, Ph.D. 1983-84 Unknown
Arthur E. Jackson, Ph.D. 1985-86 Law Office of AEJ
Stockton, NJ
Henry G. Zot, Ph.D. 1986-88 Professor
Dept. Physiology
UT Southwestern
Dallas, TX
Mary H. Majercik, Ph.D. 1987-90 Deceased
Satya P. Yadav, Ph.D. 1990-91 Unknown
Fang Chen, Ph.D. 1990 Research Scientist
Univ. of Pennsylvania
Philadelphia, PA
Marilyn K. Glassberg, M.D. 1991-92 Associate Professor
Pulmonary Division
Dept. of Medicine
Univ. of Miami
Miami, FL
Kou-Cheng Peng, Ph.D. 1993-95 Senior Scientist
Taipei, Taiwan
Krassimira Angelova, Ph.D. 1993-94 Assoc. Research Scientist
(retired) Dept. Biochemistry & Mol. Biol.
Univ. of Georgia
Athens, GA
Adviye Ergul, M.D., Ph.D. 1995-1996 Professor
Dept. Physiology
Medical Coll. of GA
Augusta, GA
Lisa Kelly, Ph.D., D.V.M. 2000-2003 Veterinary Medicine Practice
Athens, GA
Vis. Sci. & Fac. Assoc.YearsCurrent Position
Ronald Brown, M.D.1979 Professor of Medicine
University of Oklahoma
Oklahoma City, OK
(Sabbatical)
Zi-yi Liu, M.D.1986-88 Professor & Head
(retired) Dept. of Biochemistry
Zhejiang Medical University
Hangzhou, China
(WHO Visiting Scientist)
Shirley El-Maasarany, M.D.,Ph.D. 1988 Professor
Dept. of Anatomy
Alexandria University
Alexandria, Egypt
(Visiting Scientist)
Yi Wang, B.S.1989-90Unknown
Mary H. Majercik, Ph.D.1990-91Deceased
Makoto Ujihara, M.D.,Ph.D.1991-92Dept. Medicine
Tokyo Women's Medical College
Tokyo, Japan
Hiroaki Yoshida, M.D., Ph.D.1991-93Dept. of Ob/Gyn
Sendai Univ.
Sendai, Japan
Marilyn K. Glassberg, M.D.1992-93Associate Professor
Pulmonary Division
Dept. of Medicine
Univ. of Miami
Miami, FL
Prema Narayan, Ph.D.1993-2005Associate Professor
Dept. of Physiology
Southern Illinois University School
of Medicine
Carbondale, IL
Do-Young Yoon, Ph.D.1994Scientist
Genetic Engineering Research Inst.
Taejon, Korea
Krassimira Angelova, Ph.D.1994-pres.Assoc. Res. Scientist
Dept. Biochemistry & Mol. Biol.
Univ. of Georgia
Athens, GA
Adviye Ergul, M.D., Ph.D.1996-1999Professor
Dept. Physiology
Medical College of Georgia
Augusta, GA
Susanne W. Warrenfeltz, Ph.D.2004-2008Science writer
Athens, GA
Axel P.N. Themmen, Ph.D. 2007 Associate Professor Department of Internal Medicine
Eramus School of Medicine
Rotterdam, The Netherlands
(Sabbatical)
BIBLIOGRAPHY
Contents / Page Number(s)Juried Publications: Science / 14-32
Books, Book Chapters, Reviews, and Symposium Proceedings: Science / 32-36
Short Reports (Special Issues) Edited: Science / 36-38
Books and journals (Special Issues) Edited: Science / 38-39
Note on Published Abstracts and Meeting Presentations: Science / 39
Essay: Science / 39
Juried Publication: Medical Education / 39
Juried Publications: History & History of Science / 39
Juried Book: History, History of Science, and Art / 40
JURIED PUBLICATIONS: SCIENCE