From

Dr.MukulPratapBishnoi

Preliminary M.D. (Ayu) Scholar in Samhita,

Department of SamhitaSamskruta and Siddhanta,

S.D.M. College of Ayurveda and Hospital, P.O. Box 164,

Hassan – 573 201.

To

The Registrar,

Rajiv Gandhi University of Health Sciences,

Karnataka, Bangalore.

Through

The Principal

S.D.M. College of Ayurveda and Hospital,

Hassan- 573201.

Respected Sir,

Subject: Submission of completed proforma for Registration of Subject for Dissertation.

I request you to kindly register the below mentioned subject against my name for the submission of the dissertation to Rajiv Gandhi University of Health Sciences Karnataka, Bangalore for partial fulfillment of M.D. (Ayurveda).

Title of the Dissertation: “A CLINICAL STUDY OF SAPTAPARNA AS A UDARDAPRASHAMANADASHEMANI”

Herewith, I am enclosing completed proforma of synopsis for registration of subject for Dissertation.

Thanking you,

Yours faithfully,

Place: Hassan

Date: (DR. MUKUL PRATAP BISHNOI)

RAJIV GANDHI UNIVERSITY OF HEALTH SCIENCES KARNATAKA, BENGALURU

COMPLETED PROFORMA FOR THE REGISTRATION OF SUBJECT

(SAMHITA) FOR THE DISSERTATION IN M.D. (AYURVEDA)

“A CLINICAL STUDY OF SAPTAPARNA AS A UDARDAPRASHAMANA DASHEMANI”

By

Dr. MUKUL PRATAP BISHNOI

1st M.D. (Ay) Scholar

P.G. Studies in SAMHITA

SDM COLLEGE OF AYURVEDA & HOSPITAL,

Hassan, Karnataka.

GUIDE

Dr. MALLIKA K.J. (M.D.)AYU

Professor, Department of Samhita, Samskruta and Siddhanta

S.D.M.C.A, Hassan-573201

2012-13

SDM COLLEGE OF AYURVEDA & HOSPITAL,

Hassan, Karnataka

RAJIV GANDHI UNIVERSITY OF HEALTH SCIENCES, KARNATAKA,
BENGALURU.

ANNEXURE – II

COMPLETED PROFORMA FOR REGISTRATION OF SUBJECT FOR DISSERTATION

1. Name of the Candidate:dR. MUKUL PRATAP BISHNOI

and AddressPRELIMINARY M.D. (AYU) SCHOLAR.

(IN BLOCK LETTERS)Department of samhita samskruta and siddHanta.

S.D.M. College of Ayurveda AND Hospital, P.O. Box 164, HassaN–573201.

permanent ADDRESS: DR. MUKUL PRATAP BISHNOI

S/O DR.RAKESH KUMAR BISHNOI

HOUSE NO. 1193,

KABLIGATE, MAWANA

MEERUT- 250401

UTTAR PRADESH

2. Name of the Institution: S.D.M. College of Ayurved

AND Hospital, Hassan – 573 201.

3. Course of the Study in: M.D. (Ayu), SAMHITA

SUBJECT

4. Date of Admission to : 16.10.2012

the course

5. TITLE OF THE DISSERTATION:

“A CLINICAL STUDY OF SAPTAPARNA AS A UDARDAPRASHAMANA DASHEMANI”

6. BRIEF RESUME OF THE STUDY:

6.1 need for the study:

In CarakaSamhita under BhesajaChatusaka, ShadvirechaniyasatashatiyaAdhyaya, while enumerating fifty MahakshayaUdardaprashamana1 is mentioned. It contains ten drugs acting on Udarda. Cakrapani and Bhavaprakasha comments on Udarda as “Vartidastakara”2,3 - skin lesions characterized by elevation and wheal like patch. Though UdardaprashamanaDashemaniis enumerated by Caraka but explanation about Udarda is not available in CarakaSamhita. Only three times Udarda word has been used. On referring other texts it is understood that Sheetpitta, Udarda and Kotha are considered as clinical presentations with overlapping symptoms.4Analyzing the doshic involvement, Udarda is Kaphapittaja and Sheetapitta is Vatapittaja vyadhi.5,6 In order to difference between overlapping presentation a retrospective approach is required, so akaphapittaShamakadravya which acts on Udarda and mentioned in Udardaprashmanadasemani i.e. Saptaparna7 is taken up for the study to establish its action as Udardaprashmana drug.

6.2 Review of the literature:

Udarda is a disease caused by cold breeze which in turn vitiate Kaphaand Vata. These Dosha when associated with Pittabegin to travel in the body externally and internally produce the symptoms predominant of kapha.8Elevated patches resembling that produced by the sting of the wasp associated with severe itching and pricking pain, vomiting, fever and feeling of burning sensation are the characteristic features of udarda4. Elevated, reddish, irritating, round patches caused by Kaphaduring SishiraRituis also known as udarda8.UdardaprashamanaDashemaniincludesTinduka, Priyala, Badara, Khadira, Kadara, Saptaprna, Ashwakarna, Arjuna, Asana and Arimeda. The drugs of this Dashemaniare indicated in the condition known as Udarda1.Saptaparna(Alstoniascholaris) is one among the drugs mentioned in UdardaprashamanaDasemani.Saptaparna is having TiktaKasaya Rasa, LaghuSnigdhaGuna, UsnaViryaand KatuVipaka. It is Kaphapittahara in nature9. Saptaparna is also mentioned under Tikta skanda10, KashayaSkanda11, Kusthagna12, Sirovirachena13by AcharyaCharaka and under AargvadadiGana14and LakshadiGana15by AchrayaSushruta.

Previous Research Works Conducted:

Not available

6.3 Objectives of the Study:

1. To evaluate Saptaparna as anUdardaPrashamanaDravya.

7. Materials and Methods:

7.1Saptaparna Ghana Vati.

7.2 Preparation Method:SaptaparnaTwakKashayawill be prepared as per method given in Sharangadhara Samhita16.The Kashayathus obtain will be reheated for preparing Ghansara as per the method given by YT Acharya. The Vati of uniform size weighing 500mg will be prepared.

Drug Authentication: Will be done from the Department of DravyaGuna, SDMCAH, Hassan.

Storage Method: Prepared drug will be stored in sealed plastic pouches each containing 30 tabs.

Presentation: Tablet form(500mg)

Dosage: 2 tabs twice daily

Time of Administration: Immediately after food (VyanaVata Kala)

Anupana:UsnaJala.

Source of Data:

Patients will be selected from outpatient and inpatient department of S.D.M. College of Ayurveda and Hospital, Hassan.

Methods of Collection of Data:

Sample will be selected from the OPD and IPD in S.D.M. Hassan.

Treatment Group:

Single Group Clinical Study.

Diagnostic Criteria:

Kapha-PittaVriddhiLakshanawith VaratiDashtaakara.

Inclusion Criteria:

1. Patients with complaints of Varatidashtakaralesions over skin.

2. Patients with complaints ofKandu,Toda, Chardi, Jwara, Vidaha.

Exclusion Criteria:

Hetuof Sheetapitta

INVESTIGATION:

  • Absolute Eosinophil Count

Assessment Criteria:

Assessment will be based on Udarda, Kapha and PittaDoshaVriddhiLakshana.

Subjective Parameters:

  • Sheetalta
  • Kandu
  • Sthirata
  • Dahayuktasotha
  • Raga
  • Paka
  • Toda
  • Chardi
  • Jwara

Objective Parameters:

  • Varatidashtakara
  • Number of lesions
  • Discolouration
  • Utsedha

Duration of Treatment:

  • Duration of treatment is 15 days.

7.3DOES THE STUDY REQUIRE ANY INVESTIGATION OR INTERVENTIONS TO BE CONDUCTED ON PATIENTS OR OTHER HUMAN OR ANIMALS, IF SO, PLEASE DESCRIBE BRIEFLY: Yes.

7.4 HAS ETHICAL CLEARANCE BEEN OBTAINED FROM YOUR INSTITUTION? YES

8. LIST OF REFERENCES

1. TripathiBrahmanananda. CharakaSamhita Of Agnivesha,Reprint ed. Varanasi: ChaukhambaSurbharitiPrakashan ; 2005. p. 94

2. Acharya YT. CharakaSamhita Of Agnivesha,Reprint ed. Varanasi: ChaukhambaOrientalia ; 2011. p32.

3. Mishra BS. Bhavaprakasha of Sri Bhavvamisra. 8thed. Varanasi: Chaukhamba Publication; 2003. p 543.

4. TripathiBrahmanananda. Madhavnidanam of Sri Madhavakara.Reprint ed. Varanasi: ChaukhambaSurbharitiPrakashan; 2003. p 222.

5. ibid. p 222.

6. Jain SL. Vangasena of Vashya SG ed. Bombay: Khemraj Sri KrishnadasPrakashan; 2003.p 646

7. Sharma PV. DravyagunaVijnanavol 2. 14th ed. Varanasi: ChaukhambaBharati Academy; 1993. p 703.

8. Murthy KRS. Madhavnidanam of Sri Madhavakara. 2nded. Varanasi: ChaukhambaOrientalia; 1995 . p 165.

9. ibid, p 703.

10. TripathiBrahmanananda. CharakaSamhitaOfAgnivesha.Reprint ed. Varanasi: ChaukhambaSurbharitiPrakashan; 2005. p 782.

11. TripathiBrahmanananda. CharakaSamhitaOfAgnivesha.Reprint ed. Varanasi: ChaukhambaSurbharitiPrakashan; 2005. p 783.

12. TripathiBrahmanananda. CharakaSamhitaOfAgnivesha.Reprint ed. Varanasi: ChaukhambaSurbharitiPrakashan; 2005. p82.

13. TripathiBrahmanananda. CharakaSamhitaOfAgnivesha.Reprint ed. Varanasi: Chaukhamba Surbhariti Prakashan; 2005. p 785.

14.Shastri AB. SusrutSamhita.14th ed.Varanasi: Chaukhamba Sanskrit Santhan; 2003. p142.

15.ShastriAB. SusrutSamhita. 14thed.Varanasi: Chaukhamba Sanskrit Santhan ; 2003. p146.

16. TripathiBrahmanananda. SarngadharaSamhita. Reprint ed.Varanasi:Chaukhamba Surbhariti Prakashan ;2004 .p210.

9. SIGNATURE OF THE CANDIDATE :

10. REMARKS OF GUIDE:

11. NAME AND DESIGNATION OF:

(IN BLOCK LETTERS)

11.1 GUIDE : DR. MALLIKA K.J. M.D.(AYU)

PROFESSORDEPT OF SAMHITA SAMSKRUTA AND SIDDHANTA.

SDM COLLEGE OF AYURVEDA& HOSPITAL, HASSAN-573201

11.2 SIGNATURE :

11.3 HEAD OF THE DEPARTMENT: DR. MALLIKA KJ, M.D.(AYU)

(IN BLOCK LETTERS)PROFESSOR DEPT OF SAMHITA SAMSKRUTHA AND SIDDANTA.

SDM COLLEGE OF AYURVEDA & HOSPITAL, HASSAN-573201, KARNATAKA

REMARKS:

11.4 SIGNATURE :

12 REMARKS OF THE CHAIRMAN

AND PRINCIPAL:

12.1 PRINCIPAL: Dr. PRASANNA N. RAO M.S. (Ayu) Ph.D

PRINCIPAL

SDM COLLEGE OF AYURVEDA, HASSAN

12.1 SIGNATURE: