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Curriculum Vitae

(Revised March 2007)

Name: Jefferson Bruce Prince

Office Address: Child Psychiatry Child Psychiatry

ACC 725 4th Floor

Massachusetts General Hospital North Shore Children’s Hospital

15 Parkman Street 57 Highland Avenue

Boston, MA 02114 Salem, MA 01970

Office Phone: 617-724-5600 978-354-2613

E-Mail:

Date of Birth: September 6, 1964

Place of Birth: Columbia, South Carolina

Education:

1991 M.D., Emory University School of Medicine, Atlanta, GA

1986 B.S., Georgetown University (Biology), Washington, DC

Postdoctoral Training:

Internships and Residencies:

1991-1992 Transitional Internship (six months medicine, four months pediatrics, two months neurology), Department of Medicine, Emory University Hospitals, Atlanta, GA

1992-1995 Resident in Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA

1994-1995 Chief Resident, Acute Psychiatry Service, Massachusetts General Hospital, Harvard Medical School, Boston, MA

1995-1997 Clinical Fellow in Child Psychiatry, Massachusetts General and McLean Hospitals, Harvard Medical School, Boston, MA

Licensure and Certification:

1992 National Board of Registration in Medicine

1996 Board of Registration, State of Massachusetts, #81600

1996 American Board of Psychiatry and Neurology, General Psychiatry, #42609

2001 American Board of Psychiatry and Neurology, Child and Adolescent Psychiatry, #5101

Academic Appointments:

1992-1995 Clinical Fellow in Psychiatry, Harvard Medical School, Boston, MA

1995-1997 Clinical Fellow in Child Psychiatry, Harvard Medical School, Boston, MA

1997- Instructor in Psychiatry, Harvard Medical School, Boston, MA

Hospital Appointments:

1991-1992 Intern, Department of Medicine, Emory University Hospitals, Atlanta, GA

1992-1995 Resident in Psychiatry, Massachusetts General Hospital, Boston, MA

1993-1996 Moonlighting in Adult Psychopharmacology Clinic, Chelsea MGH,

1994-1995 Chief Resident, Acute Psychiatry Service, Massachusetts General Hospital

1995-1997 Clinical Fellow in Child Psychiatry, Massachusetts General and McLean Hospitals

1995-1998 Staff Psychiatrist, Correctional Healthcare Solutions, Essex County House of Corrections, Middleton, MA

1996-1997 Staff in Child Psychiatry, North Shore Children’s Hospital, Salem, MA

1997-1999 Medical Director, Outpatient Mental Health and Pediatric Psychopharmacology Clinics, North Shore Children’s Hospital, Salem, MA

1997-1999 Staff, Boston Emergency Services Team, Boston, MA

1997- Staff, Child Psychiatry Clinic, Massachusetts General Hospital, Boston, MA

2000- Director, Child and Adolescent Psychiatry, North Shore Medical Center, Salem, MA

2000- Assistant Psychiatrist, Massachusetts General Hospital

2002- Associate Chief of Psychiatry, Salem Hospital, Salem, MA

2004 Medical Director, Massachusetts Child Psychiatry Access Project, Salem, MA

Major Committee Assignments

2000- Children’s Mental Health Task Force, Massachusetts Chapter of the American Academy of Pediatrics, Massachusetts Medical Society

2000- Ethics Advisory Committee, North Shore Medical Center

2000-2001 Professional Advisory Board, WellChild Foundation, Blue Cross & Blue Shield of Massachusetts

2001- 2007 Committee on Continuing Medical Education, North Shore Medical Center

2002-2005 Professional Advisory Board, Children and Adults with Attention Deficit Disorder (CHADD)

2002-2007 Committee on Pharmacy and Therapeutics, North Shore Medical Center

2002-2004 Editorial Advisory Board, Attention Magazine

2003- Board of Directors, Children’s Trust Fund

2004- Professional Advisory Board, Adult Attention Deficit Disorder Association

2004- Ad Hoc Member Essex County Child Fatality Review Team

Honors and Awards:

1996 Laughlin Fellow of the American College of Psychiatrists

1996 Eli Lily Pilot Research Award for “Nortriptyline for Attention Deficit Hyperactivity Disorder in Children and Adolescents”

1998 Partners in Excellence Award for development and growth of Pediatric Mental Health Clinic, North Shore Children’s Hospital

2005 Best Doctors in America, Best of Boston

Memberships in Professional Societies:

1987- American Medical Association

1992- American Psychiatric Association

2002- American Academy of Child and Adolescent Psychiatry

Reviewer for Scientific Journals (ad hoc):

1998- Journal of the American Academy of Child and Adolescent Psychiatry

2000- Harvard Review of Psychiatry

2001- Expert Opinion on Investigational Drugs

2001- Expert Opinion in Pharmacotherapy

2003- CNS Drugs

2003- Canadian Institutes of Health Research

2004- Journal of Child and Adolescent Psychopharmacology

2004- Journal of Developmental and Behavioral Pediatrics

2006- Journal of Clinical Psychiatry

2006 Comprehensive Psychiatry

2006 Pediatrics

Research Experience:

1985-86 Investigator, "Role of retinoic acid in the differentiation of embryonal carcinoma cells" (Undergraduate Thesis)

1993 Co-Principal Investigator, "Clonidine for ADHD-associated sleep disturbances: A systematic review of 62 cases"

1993 Investigator, "Efficacy of desipramine in adults with attention deficit hyperactivity disorder"

1994 Co-Principal Investigator, "Pocket-sized electronic referencing: a pilot study of physician acceptance and usefulness"

1995 Investigator, "Effectiveness and tolerability of tomoxetine in adults with attention deficit hyperactivity disorder"

1995- Investigator, “The clinical course of prepubertal mania: A systematic review of 70 cases”

1995- Co-Principal Investigator, “Co-administration of stimulants with desipramine: Effect on desipramine plasma levels”

1995 Investigator, “Efficacy of magnesium pemoline in adolescents and adults with attention deficit hyperactivity disorder”

1996 Co-Principal Investigator, “A double blind discontinuation phase study of nortriptyline for attention deficit hyperactivity disorder”

1996 Investigator, “Safety and efficacy of depakote in acute mania in adolescents and children”

1996 Investigator, “Assessment of autonomic nervous system activity controlling cardiac function in the treatment of ADHD and other psychiatric disorders

1996 Investigator, “ABT-418 vs. Placebo in Adults with ADHD”

1997 Site Investigator, “A double blind placebo controlled trial of buspirone vs. placebo in children”

1997 Investigator, “Safety and pharmacokinetic study of tomoxetine hydrochloride in pediatric ADHD”

1998 Investigator, “Efficacy of olanzapine in juvenile bipolar disorder”

1998 Site Investigator, “A double blind placebo controlled trial of venlafaxine XR in adolescent depression”

1998 Principal Investigator, “A double blind placebo controlled trial of bupropion SR for ADHD in adults with bipolar disorder”

1998 Investigator, “Tolerability and effectiveness of Oros Methylphenidate in pediatric ADHD”

1999 Co-Principal Investigator, “A open trial of bupropion SR for ADHD in adults with substance use disorder”

2000  Investigator, “A phase II, multicenter, randomized, double-blind, placebo-controlled study of GT-2331 in adults with attention deficit hyperactivity disorder”

2000 Investigator, “A double-blind placebo controlled study of the effectiveness of paroxetine in the treatment of social phobia in children and adolescents”

2000 Site-Investigator (North Shore Children’s Hospital) “A double-blind placebo controlled trial of bupropion in the prevention of tobacco use in adolescents with ADHD followed by an eight week open label extension”

2000 Investigator, “A double-blind placebo-controlled simulated classroom study of modafinil in children and adolescents with attention-defict/hyperactivity disorder

2000 Investigator, “An open-label assessment of paroxetine in children and adolescents with obsessive-compulsive disorder or major depression”

2000  Investigator, “A phase III double-blind placebo-controlled trial of the safety and efficacy of fixed doses of tomoxetine in children and adolescents with attention-deficit/hyperactivity disorder”

2000 Site-Investigator (North Shore Medical Center) “A double-blind placebo controlled trial of fluoxetine vs. St John’s Wort in the treatment of major depression in adults”

2001  Investigator, “A four week open-label pharmacokinetic study of modafinil in children with ADHD”

2001  Investigator, “Study of the pharmacokinetics of paroxetine in children and adolescents”

2001 Investigator, “Study of the pharmacokinetics of olanzapine in children and adolescents”

2002 Investigator, “Open-Label Comparative Study of Risperidone versus Olanzapine For Mania in Preschool Children 4 to 6 Years of Age with Bipolar I or Bipolar II Disorder”

2002 Investigator, “Open-Label Study of Ziprasidone for the Treatment of Mania in Children and Adolescents with Bipolar I and Bipolar II Disorder”

2003 Investigator, “A Randomized, Double-Blind Placebo-Controlled Study of Atomoxetine Hydrochloride in Adolescents with Attention Deficit/Hyperactivity Disorder and Comorbid Depressive Disorder”

2003 Investigator, “A Randomized, Double-Blind Placebo-Controlled Study of Atomoxetine Hydrochloride in Children and Adolescents with Attention Deficit/Hyperactivity Disorder and Comorbid Anxiety”

2003 Investigator, “A Phase III, Randomized, Double-Blind, Parallel-Group, Placebo-Controlled Safety and Efficacy Study of Adderall XR in Children and Adolescents Aged 6-17 with Oppositional Defiant Disorder”

2003 Investigator, “Open-Label Comparative Study of Concerta versus Adderall in the Treatment of ADHD in Youth and Adults with Bipolar I and Bipolar II Disorder”

2003 Investigator, “Open-Label Study of Concerta in the Treatment of ADHD in Youth and Adults with Bipolar I, Bipolar II and Bipolar Spectrum Disorder”

Major Research Interests:

1. Characterization of attention deficit hyperactivity disorder in children, adolescents, and adults.

2. Characterization of depressive, bipolar, anxiety and substance use disorders in children and adolescents

3. Delivery of psychiatric services in health care systems

4. Medical ethics

Teaching Experience:

Lecturer to Medical Students and Residents:

1994- Lecturer (medical students), core curriculum in Psychiatry, Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School

1994- Lecturer (residents), core clinical curriculum in Psychiatry, Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School

1997- Lecturer (child psychiatry fellows), core clinical curriculum in Psychiatry, Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School

1998 Lecturer (Psychology Interns), core curriculum in Psychology, North Shore Medical Center

Supervision:

1994- Clinical Supervisor, Acute Psychiatry Service, Massachusetts General Hospital and Harvard Medical School

1997- Supervisor, Child and Adult Psychiatry Service, Massachusetts General Hospital and Harvard Medical School

1997- Clinical Supervisor, North Shore Medical Center

Academic Presentations

1994 Academic Conference: "Attention Deficit Disorder in Adults: Should We Pay Attention?” Massachusetts General Hospital, Harvard Medical School, Boston, MA

1994 Academic Conference: "Attention Deficit Hyperactivity Disorder: Neurobiology and Treatments", Massachusetts General Hospital, Harvard Medical School, Boston, MA

1995 Pediatric Grand Rounds “Attention Deficit Hyperactivity Disorder in Children and Adolescents”, North Shore Children’s Hospital, Salem, MA

1995 “Stress and Its Effects on Residents”, Massachusetts General Hospital, Boston, MA

1995 Academic Presentation to Annual Review of Pediatric Conference for Continuing Medical Education, “Attention Deficit Hyperactivity Disorder Through the Lifespan”, Lake George, NY

1996 Symposia: Does juvenile bipolar disorder exist? New research and findings: Parts I and II. Symposia for American Academy of Child and Adolescent Psychiatry, Philadelphia, PA 1996 12: 70-71.

1997 Symposia for Brain Awareness Week sponsored by Harvard Medical School at The Museum of Science, “Attention Deficit Hyperactivity Disorder”, Boston, MA

1998 Psychiatry Grand Rounds, " Attention Deficit Hyperactivity Disorder in Adults”, Emerson Hospital, Concord, MA

1998 Pediatric Grand Rounds, “Mood Disorders in Children and Adolescents”, North Shore Children’s Hospital, Salem, MA

1998 Psychopharmacology Course for Continuing Medical Education, “Mood Disorders in Children & Adolescents”, Massachusetts General Hospital, Boston, MA

1998 National Alliance for the Mentally Ill of Oklahoma, “Survey of Childhood Psychopathology” and “Childhood Depression”, Annual Meeting, Tulsa, Oklahoma

1998 Academic Presentation, “Pharmacological Treatment of Anxiety Disorders in Children and Adolescents”, North Shore Medical Center, Salem, MA

1998 Academic Presentation to Alliance for the Mentally Ill of Erie County, “Attention Deficit Hyperactivity Disorder and Mania in Children and Adolescents”, Erie County, PA

1998 Pediatric Grand Rounds, “Treatment of Bipolar Disorder in Children and Adolescents”, North Shore Children’s Hospital, Salem, MA

1999 Academic Presentation to Massachusetts Society of Neuropsychology, “Recent Advances in Pharmacotherapy”, Spalding Rehabilitation Hospital, Boston, MA

1999 Pediatric Grand Rounds, “Recent Advances in the Treatment of Anxiety and Depression in Children and Adolescents”, Beverly Hospital, Beverly MA

1999 Psychiatric Grand Rounds, “Recent Advances in the Treatment of Attention Deficit Hyperactivity Disorder”, University of Connecticut, Farmington, CT

1999 Pediatric Grand Rounds, “Cardiovascular side effects of psychotropic medications used in Children and Adolescents” given with Barry Ticho, M.D. from Pediatric Cardiology Massachusetts General Hospital, North Shore Children’s Hospital, Salem, MA

1999 Consulting Rounds, Lynn Community Health Center “Review of Psychotropic Medications Used in Children & Adolescents”, Community Health Center, Lynn, MA

1999 Annual Nursing Forum, “Diagnosis and treatment of Anxiety Disorders in Children and Adolescents”, North Shore Medical Center, Salem, MA

1999 Advances in Identification and Treatment of Childhood Behavioral Disorders: “Why children misbehave: a neurological, developmental, and physiological perspective” and “The psychopharmacologic management of children with disruptive behavior”, Colby College and Maine General Medical Center, Waterville, Maine

1999 Current issues for special education administrators “What to expect and not expect from psychotropic medications used in children and adolescents”, Landmark School, Prides Crossing, MA

1999 Kaiser Permanente Second Annual ADHD Conference: ADHD through the lifespan: integrated treatment in managed care settings “Psychopharmacology: using the stimulants” & “Psychopharmacology: refractory cases”, Vail, Colorado

1999 “Educational Challenges for the New Millennium”, Academic Presentations on “Attention Deficit Hyperactivity Disorder” & “Adolescent Depression”, Marblehead, MA

1999 Zarrow Mental Health Symposium, “Today’s Adolescents, Tomorrow’s Adults: Planning to Prevent Youth Violence and Self-destructive Behavior” “The Clinical Presentation, Diagnosis, and Treatment of Depression in Children and Adolescents”, Tulsa, Oklahoma

1999 Montana State Conference on Mental Illness: “Recovery Into The Future” “Attention Deficit Hyperactivity Disorder Through The Lifespan” and “Recognition and Treatment of Juvenile Mood Disorders”, Great Falls, Montana

1999 Psychopharmacology Course for Continuing Medical Education, “Juvenile Mood Disorders” Massachusetts General Hospital, Boston, MA

1999 A controlled trial of nortriptyline for ADHD. In New Research in the treatment of ADHD Scientific presentation at the Annual Meeting of the American Academy of Child and Adolescent Psychiatry, Chicago, Ill; S-42E, October 1999.

1999 Academic Presentation “A Long Strange Trip: Adolescents Discuss Their Own World” as part of “The Alienated Child” Conference sponsored by North Shore Medical Center, Salem, MA

2000 Continuing Training, Full Day Symposia on “Update & Overview of Psychiatric Medications Used in Children and Adolescents” to Department of Social Services, Boston, MA

2000 Continuing Medical Education for School Nurses“An Update and Overview of Psychiatric Medications Used in Children and Adolescents” ,Salem Hospital, Salem, MA

2000 Keynote address, Attention Deficit Disorders Association, Southern Region, “ADD2000: A Comprehensive Approach” “Update on the Neurobiology of ADD”; “Bipolar Disorder in Adolescents”; “Recent Advances in the Pharmacotherapy of ADD” Irving, Texas

2000 Child and Adolescent Psychopharmacology, Moderator, “Panel: Ask the Experts” for Continuing Medical Education, Massachusetts General Hospital, Boston, MA

2000 Child Psychopharmacology State-of-the-Art-Therapies for Continuing Medical Education, “Pharmacotherapy of Anger & Aggression in Children & Adolescents” McLean Hospital, Belmont, MA

2000 18th Annual Conference of The Learning Disabilities Network “Unlocking Learning Potential”. “An Update & Overview of Psychotropic Meds Used in Children & Adolescents” Randolph, MA