Date of Submission: 08.IX.1998

Title#PRA5184

Development of Micelle Adsorbing Preparations for Detoxication of Salts of Heavy Metals and Radionuclides

Short Title:

Micelle Absorbing Detoxication for Heavy Metals and Radionuclides

Technology Area:

Remediation and Decontamination / ENV-RED

Person (s) for Contact:

Murat K. Gilmanov, Doctor of Sciences, Prof., Member-Correspondent of Academy of Sciences of the Republic of Kazakstan

E-mail:

Phone: 7-3272-676306

Fax: 7-3272-671947

E-mail:

Research Institute Where the Above Person Belongs:

Ajthozhins Institute of Molecular Biology and Biochemistry, Academy of Sciences of the Republic of Kazakhstan (Ajthozhins Inst RKz)

Present Status of Research

1. Brief Description of Research

Problems of detoxication of radionuclides and heavy metals of the Semipalatinsk region and regions of ecological disaster are a major problem. The development of micelle adsorbing preparations for such specific purposes has not previously been undertaken. We are involved in the development of special untoxic micelle adsorbing preparations, based on phosphatidylinositol for use in regions of nuclear testing and regions of ecological disasters in Kazakstan.

This project concerns the development of effective micelle adsorbing preparations, which can be used in three ways:

  1. Detoxication of radionuclides in people, injured as a result nuclear tests.
  2. Detoxication of salts of heavy metals in the population, injured in regions of ecological disasters.
  3. Detoxication of heavy metals and radionuclides in domestic animals before contact is made with them.

Expected Results: micelle adsorbing preparations will be developed for detoxication of salts of heavy metals and radionuclides in human and animal organisms.

Part of the investigation will be carry at the Scientific Research Agricultural Institute. (The National Centre of Biotechnology of the Republic of Kazakstan).

2. Legal Aspects

Patent application for the method for preparing phosphatidylinositol (Gilmanov et al. Method for preparing phosphatidylinositol from vegetable matter. United States Patent 4,977, 091 Dec. 1, 1990).

3. Special Facilities in Use and Their Specification

None in this research.

4. Scientific Papers

M.K. Gilmanov at all. 5th International Symposium on Inorganic Nitrogen Assimilation. July 13-17 1998 . Luso- Portugal. Books of abstracts.

5. Potential Foreign Collaborators

Mirsaatkham Mirsakhakimovich Rakhimov. Tashkent State University, Usbekistan.

Future Research Direction

1. Possibility of Application

Data will be used in medicine, sanitation, immunology and ecology.

2. Budget Necessary for Research of this Application

$300,000 over 3 years.

3. Suggestions on Co-operation with Foreigners

We invite leading foreign medical, toxicology, sanitation and ecology laboratories for collaboration.

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