CV Form

Dr. M . Shekari MD.PhD in Human Molecular Genetics

Associate Professor, Department ofGenetics, Faculty of Medicine, HormozganUniversity of Medical Science, Bandar Abbas –Iran

CV (Curriculum Vitae)

Last updated aprile , 2017

A.Personal Information

First Name: Mohammad

Last Name: Shekari

Date of Birth:August. 23, 1964

Citizenship: Iranian

Languages: Fluent in English, ,A2 in Germany ,Fluent in Romanian and farsi

Tel: (office) (+98 763) 33354459

Cell phone: (+98 )917 3616509)

E-mail:

B. Academic Appointments

YearAcademic Institution

  1. 2008-present Faculty Member, Faculty of Medicine Bandar-Abbas-Iran
  2. 2010 President of HUMS Chancellor for the 11 th National Scholar Congress
  3. 2009-present Editorial Board Medical Journal HUMS
  4. 2009-present Fellow, Center for Infectious Diseases and Tropical Medicine, HUMS,
  5. 2008-2016 Director Center for Molecular Medicine Research Center (HUMS)
  6. 2011-2016 Member of Prevention committee for Thalassemia network in Iran,
  7. 2012-2016 Supervisor of PhD by Research Scholarships (PhD candidates), HUMS
  8. 2010-2016 Chancellor HUMS, Bandar -Abbas, Iran
  9. 2011-present: Director at Bandar- Abbas Medical Diagnostic Genetic Center (BMGC)

C : Molecular Laboratory Skills :

-Genetic polymorphism on analysis in different method such as PCR-RFLP, ARMS-PCR, SSCP, sequencing PCR-VNTR, microsatellite, and different PCR-method based molecular study .

-Understanding and proven practical experience in molecular biology strategies and techniques e.g., nucleic acid isolation, purification, PCR and electrophoresis.

-Gene expression analysis such as RT-PCR, gene cloning,Real time PCR, protein analysis, flowcytometry, ELISA .

-Understanding of genotyping techniques (e.g. qPCR and HRM A).

-Prenatal diagnosis (PND) of hematologic disease such as -thalassemia,Sickle cell disease (PCR based method) , and other single gene disease diagnosis.

-Cytogenetic study and chromosome analysis.

-Epigenetic study and DNA methylation research laboratory experience.

-Molecular cytogenetic technique in cancer solid tumour research.G.

-QF-PCR anaysis in prenatal chromosomal aneuploidy .

- mi-RNA gene expression resarch study in breast cancer .

- Primer Design and Practical experience with sequencing technologies.

-Gene dosage analysis .

-Experience of mammalian cell culture.

-QF-PCR , MLPA andPaternity anaysis by gene scan and other bioinformatics

software analysis.-

-Theoretical understanding of genome engineering techniques .

-Ability to test and implement new approaches and techniques including troubleshooting.

- Capable of working to a schedule and delivering a variety of challenging projects simultaneously within agreed deadlines.

D: Publications

1.Sobti RC, Kordi Tamandani DM, Shekari M, et al. Interleukin-1 beta gene polymorphism and risk of cervical cancer. Int J Gynecol Obstet. 2008, Apr; 101(1):47-52.

2. Kordi Tamandani DM, Sobti RC, Shekari M, et al. Impact of polymorphism in IL-1RA gene on the risk of cervical cancer. Arch Gynecol Obstet. 2008; Jun;277(6):527-33.

3. Sobti RC, Shekari M , Kordi Tamandani DM, et al. Effect of NBS1 gene polymorphism with the risk of cervix carcinoma in north Indian population. The International Journal of Biological Markers. ; Jan. 30; 2008

4.Mohammad Shekari, Ranbir Chander Sobti, Dor Mohammad Kordi Tamandani, et al. Impact of methylenetetrahydrofolate reductase (MTHFR) codon (667) and methionine synthase (MS) codon (2756) on risk of cervical carcinogenesis in North Indian population.Arch Gynecol Obstet.2008 March 20

5.Mohammad Shekari, Ranbir Chander Sobti, Dor Mohammad Kordi Tamandani, et al. Association of IL-18 gene promoter polymorphism on the risk of cervix carcinoma in North Indian population.Oncology Res..2008; 17(4):159-66.

6.Mohammad Shekari ,Ranbir Chander Sobti, , Dor Mohammad Kordi Tamandani, et al.Association of genetic polymorphism of the DNA base excision repair gene (APE-1)Asp148 Glu and HPV type(16,18) with the risk of cervical cancer in North Indian population.Cancer Biomarker.2008 :4 (2) pp.63-71.

7.Tamandani DM ,Sobti RC, Shekari M, Association of Fas-670 gene polymorphism with risk of cervical cancer in north Indian population.Clin Exp Obstet Gynecol.2008;35(3):183-6

8. Kordi Tamandani DM, Sobti, RC, Shekari M, et al. Interleukin-6 genes polymorphism and cervical cancer risk. Acta Obst Gynec Schandenavi. 2008.

9. Kordi Tamandani DM, Sobti, RC, Shekari M, et al. Impact of IFN-gama gene polymorphism on the risk of cervical cancer. Exp Oncol sep;30(3):224-9.

10.Sobti RC, Shekari M, Kordi Tamandani DM, Kaur P, Suri V, Huria A. Effect of NBS1 gene polymorphism on the risk of cervix carcinoma in a northern Indian population. Int J Biol Markers. 2008 Jul-Sep; 23(3):133-9.1.

11.Kordi Tamandani DM, Sobti RC, Shekari M, Husseini SA, Suri V. No association of TAP1 and TAP2 genes polymorphism with risk of cervical cancer in north Indian population. J Assist Reprod Genet. 2009 Mar 5

12. Tamandani DM, Sobti RC, Shekari M, Huria A. CpG Island Methylation of TMS1/ASC and CASP8 Genes in Cervical Cancer Eur J Med Res. 2009 Feb 18;14(2):71,

13.Malekzadeh K, Sobti RC, Nikbakht M, Shekari M, Hosseini SA, Tamandani DK, Singh SK.Methylation patterns of Rb1 and Casp-8 promoters and their impact on their expression in bladder cancer. Cancer Invest. 2009 Jan;27(1):70-80.

14.Azim Nejatizadeh, Mohammad Shekari, Tsering Stobdan, M A Qadar Pasha.Genetic susceptibility of angiotensin-I converting enzyme and G-protein β3-subunit gene polymorphisms to essential hypertension. Genetics in the 3rd millennium, Vol. 8, No.3, Autumn 2010 .

15. Shekari Mohammad,Kordi Tamandani DM, Malekzadeh Keyanoush. Effect of anti-inflammatory (IL-4, IL-10) cytokine genes in relation to risk of cervical carcinoma. American journal of clinical oncology ,2012 Dec;35(6):514-9

16. Sobti RC, Malekzadeh K, Nikbakht M, Sadeghi IA, Shekari M, Hosseini SA, Tamandani DK, Singh SK. Hypermethylation-mediated partial transcriptional silencing of DAP-kinase gene in bladder cancer. Biomarker, 2010 Mar;15(2):167-74.

17.Azim NejatizadehMohammad Shekari , Tsering Stobdan, M.A.Qadar Pasha. Identification of Hepatitis B Virus Surface Antigen (HbsAg) Genotypes and Variations in Chronic Carriers form Isfahan Province, Iran. Iranian J Publ Health vol.41, No.3 .2012.

18.Mahin Jamshidi,Mohammad Shekari , Azim Nejatizadeh, Keyanoush Malekzadeh ,Mahnaz Baghershiroodi, Parivash Davudian, Farzaneh Dehghan,Froogh Jamshidi. The impact of human papillomavirus (HPV) types 6, 11 in Women with genital warts. springer Arch Gynecol Obstet DOI 10.1007/s00404-012-2416-1, 2012.

19 .Efficiency of Nested-PCR in Detecting Asymptomatic Cases toward Malaria Elimination Program in an Endemic Area of Iran , Turki H1, Raeisi A2, Malekzadeh K3,

Ghanbarnejad A4, Zoghi S5, Yeryan M6, Abedi Nejad M3, Mohseni F3, Shekari,M . Iran J Parasitol. 2015 Jan-Mar;10(1):39-45.

20.Dysregulated expression of Dicer in invasive ductal breast carcinoma ,Poursadegh Zonouzi AA1, Nejatizadeh A, Rahmati-Yamchi M, Fardmanesh H, Shakerizadeh S, Poursadegh Zonouzi A, Nejati-Koshki K, Shekari M.Med Oncol. 2015 Jul;32(7):643. doi: 10.1007/s12032-015-0643-6. Epub 2015 Jun 16.

21. Fardmanesh .H, Shekari.M, Movafagh A.Upregulation of the double-stranded RNA binding protein DGCR8 in invasive ductal breast carcinoma. Gene. 2016 May 1; 581(2):146-51.

22.M. Jalilvand , M. Oloomi, R. Najafipour ,M. Shekari. An association study between CHEK2 gene mutations and susceptibility to breast cancer.Comp Clin Pathol.2017: DOI 10.1007/s00580-017-2455-x

*Total number of citations: approx.: 305:Hindex:11(based on Google Scholar)

E: Research Interests :

Cancer biology and immuno- oncology research

Epigenetic gene silencing on cancers study.

Cancer Biomarker Research.

miRNA, siRNAresearch.

Stem Cells (Banking) & Gene Cloning (Ethics).

Pharmacogenomics Research.

Cancer gene therapy

Next Generation Sequencing Assay

Clinical Genetics and Genetic counseling

Cancer Cytogenetic

My ongoing research work are miRNA and epigenetic study in breast cancer

F: Referees :

Prof.S.Mehdi Kalantar

Department of Medical Genetics ,Faculty of Medicine

Yazd University of Medical sciences

Yazd ,Iran

Email:

Tel:+98-913-1518918

Associated Prof :A.Nejatizadeh,

A.Nejatizadeh, MD., PhD.

Associate professor of Human Molecular Genetics

Department of Medical Genetics ,Faculty of Medicine

Hormozgan University of Medical sciences

Bandar Abbas

Iran

Tel:+98-917-9564291

Email:

Associated Prof :Keyanoosh Malekzadeh

Keyanoosh Malekzadeh PhD

Associate professor of Human Molecular Genetics

Department of Medical Genetics ,Faculty of Medicine

Hormozgan University of Medical sciences

Bandar Abbas

Iran

Tel: +98-9176108396

Email:

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