Instructor’s Manual

to accompany

Inquiry into Life

Thirteenth Edition

Sylvia Mader

Prepared by

Kimberly G. Lyle-Ippolito

AndersonUniversity

PREFACE

Inquiry into Life is a textbook for college freshman biology courses and covers the whole field of basic biology. The textbook emphasizes the application of biology to human life and the relationship of humans to other organisms. Students should discover basic biology principles and also understand that biology concepts are relevant to everyday living. This Instructor’s Manual is designed to assist you as you plan and prepare for classes using Inquiry into Life.

ORGANIZATION OF THE INSTRUCTOR’S MANUAL

Chapter Contents

Learning Outcomes

Learning outcomes presented in the Instructor’s Manual give the instructor a quick overview of the major themes covered in the chapter.

Lecture Outline

Each chapter in Inquiry into Life begins with a “Chapter Outline.” This outline is expanded with annotations in the Instructor’s Manual and has several functions. An instructor can use it for his/her lecture notes since it contains the important concepts from the textbook and is cross-referenced to topic heads in the textbook. The outline can be made into Microsoft Office PowerPoint slides so the students can follow along with the lecture. Or an instructor may reproduce the extended outline to give to students before or after the lecture on that particular chapter. The organization of lecture concepts is a critical decision made by each instructor. A disorganized presentation is more difficult for students to follow and the distinct concepts may not build to an overall understanding. The selection of examples to illustrate concepts, and the selection of which concepts to represent and what order they should be presented, are critical factors in good teaching. The organization given here reflects the organization and voice of the textbook author, Dr. Sylvia Mader.

Connections & DVD Resources

Each chapter in the Instructor’s Manual lists web addresses for online connections that are useful for finding further information and examples for teaching. DVD resources provide visual learning assistance for students. Producers have usually indicated their materials are appropriate for adult and college levels, and titles are listed without any recommendation as to the content, quality, or year of production. Further information can be obtained by contacting the distributors.

Lecture Enrichment Ideas

This section suggests unique presentation and lecture strategies and methods to involve students in and out of the classroom. These topics and projects are not all-inclusive, but may help an instructor try something new and increase the interest of students. Lists of suggested term paper topics are provided so a teacher doesn’t have to “reinvent the wheel.”

Essay Questions with Answers

Each section contains several essay questions with answers for inclusion on student performance evaluations.

DISTRIBUTORS OF DVDS

Amazon.com

Ambrose Video Publishing, Inc.
145 W. 45th Street, Suite 1115
New York, NY10036

1-800-526-4663

Annenberg Media

PO Box 55742
Indianapolis, IN46205-0742

1-800-532-7637

Carolina Biological Supply

2700 York Road

Burlington, NC27215-3398

1-800-334-5551

Educational Video Network

1401 19th Street
Huntsville, TX77340

1-800-762-0060

Films Media Group

Films for the Humanities and Sciences

200 American Metro Blvd., Suite 124
Hamilton, NJ08619
1-800-257-5126

Garland Science

Mortimer House

37-41 Mortimer Street

London, W1T 3JH

GB 365 4626 36

Great Pacific Media

P.O. Box 26243
Colorado Springs, CO80936

1-800-325-1956

National Geographic Catalog/Online
777 South State Road 7
Margate, FL33068

1-888-225-5647

PART I: CELL BIOLOGY

CHAPTER 1: THE STUDY OF LIFE

LEARNING OUTCOMES

1.1 The Characteristics of Life

1. Describe the characteristics of living things.

2. Place the levels of biological organization in a hierarchy.

1.2 The Classification of Living Things

1. Describe how living things are classified.

1.3 The Organization of the Biosphere

1. Describe how life is organized on the planet.

2. Discuss how humans influence ecosystems.

1.4 The Process of Science

1. Formulate a hypothesis.

2. List the steps in conducting a scientific experiment.

3. Interpret a controlled study.

1.5 Science and Social Responsibility

1. Discuss the costs and benefits of technology.

LECTURE OUTLINE

1.1 The Characteristics of Life

The diversity of life seems overwhelming, and yet all living things have certain characteristics in common.

Living Things Are Organized

A cell is the smallest unit of life. Living things can be organized in a hierarchy of levels.

Living Things Acquire Materials and Energy

Living things cannot maintain their organization or carry on life’s other activities without an outside source of materials and energy.

Living Things Reproduce

Life comes only from life.

Living Things Respond to Stimuli

Living things respond to external stimuli, often by moving toward or away from a stimulus.

Living Things Are Homeostatic

Homeostasis means “staying the same.” The internal environment of an organism stays relatively constant.

Living Things Grow and Develop

Growth, recognized by an increase in the size of an organism and often in the number of cells, is a part of development.

Living Things Have the Capacity to Adapt

Individuals of a species that are better suited to a new environment are able to reproduce and pass on these characteristics. Evolution explains both the unity and diversity of life.

1.2 The Classification of Living Things

Since life is so diverse, it is helpful to group organisms according to their similarities.

Domains

Domains are the largest classification category. There are three domains: Archaea, Bacteria, and Eukarya.

Kingdoms

Systematists are in the process of deciding how to categorize archaea and bacteria into kingdoms. The eukaryotes are currently classified into four kingdoms: protists, fungi, plants, and animals.

Other Categories

The other classification categories are phylum, class, order, family, genus, and species.

Scientific Names

Taxonomy is the assignment of a binomial, or two-part name, to each species. Scientific names are in a common language—Latin.

1.3 The Organization of the Biosphere

The organization of life extends beyond the individual to the population, community, ecosystem, and finally the biosphere (the zone of air, land, and water at the surface of Earth where living organisms are found).

The Human Species

The human species tends to modify existing ecosystems for its own purposes. Humans depend on healthy ecosystems for food, medicines, and various raw materials.

Biodiversity

Biodiversity encompasses the total number of species, the variability of their genes, and the ecosystems in which they live.

1.4 The Process of Science

Biology is the scientific study of life.

Observation

Natural events can be understood more fully by observing and studying them.

Hypothesis

After making observations and gathering knowledge about a phenomenon, a scientist comes up with a hypothesis, a tentative explanation for the natural event.

Experiment/Further Observations

Testing a hypothesis involves either conducting an experiment or making further observations.

Data

The results of an experiment are referred to as the data. Data should be observable and objective, rather than subjective or based on opinion.

Conclusion

Scientists must analyze the data in order to reach a conclusion as to whether the hypothesis is supported or not.

Scientific Theory

The ultimate goal of science is to understand the natural world in terms of scientific theories, concepts that join together well-supported and related hypotheses.

A Controlled Study

Most investigators do controlled studies in which the experimental group receives a treatment and the control group receives no treatment.

The Experiment

The pigeon pea plant is a legume with a high rate of atmospheric nitrogen conversion. Ahypothesis was outlined involving winter wheat and nitrogen fertilizer.

The Results

The results indicated that the hypothesis is not supported.

Continuing the Experiment

The investigators modified the hypothesis to involve sustained effects.

The Results

The hypothesis was supported.

Ecological Importance of This Study

This study showed that the use of a legume improved the soil to produce a better yield than the use of a nitrogen fertilizer over the long haul.

1.5 Science and Social Responsibility

The application of scientific knowledge for a practical purpose is called technology. Most technologies have benefits, but also drawbacks. Since making value judgments is not a part of science, ethical and moral decisions about technology must be made by all people.

CONNECTIONS

Committee for the Scientific Investigation of Claims of the Paranormal (CSICOP) investigates and exposes pseudoscience and publishes the Skeptical Inquirer (6/year); highly useful examples of applying science attitudes to psychic claims, etc. Available from Skeptical Inquirer,

The National Academies of Science provides a guide to research issues in the life sciences at

The Skeptics Society has a similar mission to CSICOP but does not pursue UFO and BigFoot claims and has a narrower and more intellectual focus; publishes The Skeptic available from

Sigma Xi, the Research Society discusses science attitudes and fraud in its publication Honor in Science available at a small cost,

Virtual Institute of Cryptozoology is the website for the ISC dedicated to investigating reports of rarely seen animals at

DVD RESOURCES

Biotechnology in the 21st Century, ISBN 978-1-60825-071-4, Films for the Humanities and Science,

Introduction to Designing Experiments,ISBN 978-1-4213-5431-6, Films for the Humanities and Science,

Scientific Method, ISBN 978-1-4213-7403-1,Films for the Humanities and Science,

LECTURE ENRICHMENT IDEAS

1. Describe the many properties of quartz crystals: that crystals “grow” over time, little crystals are “reproduced” at angles off the sides of parent crystals, the crystal possesses a predictable angular “structure” that is not like the chaotic environment, and sheets of quartz even show a response to environmental stimuli—they convert light to current in a piezoelectric effect! With so many features of life, why isn’t quartz considered living?

2. We are sending additional robot spacecraft to Mars to further investigate the possibility of life on Mars. In the past, we have looked for properties that life expresses on earth: respiration, growth, movement, etc. Discuss whether the model of Earth’s properties of life is the only model possible.

3. Buy a recent tabloid newspaper from the newsstands featuring a pseudoscience topic (students

readily recognize these from the grocery checkout stands). Read one brief account of a

particularly preposterous assertion and ask what is necessary for a scientist to believe this, what

internal contradictions belie its claims, and what tests would be necessary to provide it with

scientific legitimacy, etc.

4. Display an assortment of screws, bolts, nails, brads, staples and other fasteners. Ask students

to “classify” them in groups for easier display in a store, etc. On what basis do they group screws

and bolts, tacks and nails, etc. (common structures, threading, production methods,

functions, etc.)? The basis for biological classification is commonly phylogenetic origin but

likewise uses common structures and functions.

5. Have students propose various scientific experiments based on their observations. Discuss how to control the variables, how to obtain objective data, how to interpret results, and so on.

ESSAY QUESTIONS WITH ANSWERS

1. By itself, a virus cannot reproduce, grow and develop, respond to stimuli, take in material and energy from the environment, nor show any adaptation. However, it is organized with a protein coat that surrounds hereditary material. Once inside another living cell, however, the virus takes over the host’s metabolic machinery in order to grow, develop, and reproduce new virus particles. Therefore, is the virus a living or dead organism?

Answer: Scientists do not have a unanimous answer to this question because viruses have characteristics of being both alive and dead. Because viruses are unable to carry out metabolic processes themselves, some scientists prefer to consider viruses activated and inactivated.

2. Explain what is scientifically wrong with the following assertions:

a. I clang bells each day and there are no tigers around my house; therefore clanging bells drives away tigers.

Answer: There is no test with tigers present; therefore there is no cause-and-effect established.

b. If water dousing, homeopathic cures, and so on work for just me but not for anyone else, it is still science.

Answer: Science is not personal; results must be repeatable.

3. Why does evolution explain both the unity and the diversity of life?

Answer: All organisms share the same basic characteristics of life because we all share a common ancestor (unity). During the past 4 billion years, Earth’s environment has changed drastically, and the diversity of life has been shaped by the evolutionary responses of organisms to these changes (diversity).

PART I: CELL BIOLOGY

CHAPTER 2: THE MOLECULES OF CELLS

LEARNING OUTCOMES

2.1 Basic Chemistry
1. Define and give examples of matter.

2. Describe the structure of an atom, including the subatomic particles, their charges, and their location.

3. Know how the periodic table is organized.

4. Explain how isotopes differ.

5. Discuss beneficial and harmful uses for radiation.

2.2 Molecules and Compounds

1. Define a molecule and a compound.

2. Compare and contrast ionic and covalent bonds.

3. Explain why water is a polar molecule and how this enables the formation of hydrogen bonds.

2.3 Chemistry of Water

1. Describe the unique properties of water and the advantages of these properties for life.

2. Be able to define an acid and a base and be able to use the pH scale.

3. Recognize the importance of buffers to living organisms.

2.4 Organic Molecules

1. Distinguish inorganic from organic molecules.

2. Define a functional group.

3. Describe how monomers are joined to form polymers.

2.5 Carbohydrates

1. Recognize the structure of a carbohydrate.

2. Compare and contrast different types of carbohydrates.

2.6 Lipids

1. Describe the structure of the various lipids.

2. List the functions lipids play in our bodies.

2.7 Proteins

1. Describe the monomer unit of a protein and how monomer units are assembled into peptides.

2. Explain the primary, secondary, tertiary, and quaternary structures of a protein and describe the relationship between protein structure and function.

2.8 Nucleic Acids

1. Describe the structure of DNA and RNA.

2. Explain the role of ATP in the cell.

LECTURE OUTLINE

2.1 Basic Chemistry

Matter refers to anything that takes up space and has mass. All matter, both nonliving and living, is composed of certain basic substances called elements.

Atomic Structure

Elements consist of tiny particles called atoms. Protons, neutrons, and electrons make up atoms. All atoms of an element have the same number of protons. This number is called the atomic number.The atomic mass is the sum of an atom’s protons and neutrons.

The PeriodicTable

The periodic table was constructed as a way to group the elements according to certain chemical and physical characteristics.

Isotopes

Isotopes are atoms of the same element that differ in their number of neutrons.

Low Levels of Radiation

The chemical behavior of a radioactive isotope is essentially the same as that of the stable isotopes of an element so you can use small amounts of radioactive isotopes as tracers.

High Levels of Radiation

Radioactive substances in the environment can harm cells, damage DNA, and cause cancer.

Electrons

The number of electrons in the outer shell determines whether an atom reacts with other atoms.

2.2 Molecules and Compounds

A molecule is formed when two or more atoms bond together. When the atoms of two or more different elements bond together, the product is called a compound.

Ionic Bonding

The transfer of electron(s) between atoms results in ions that are held together by an ionic bond, the attraction of negative and positive charges.

Covalent Bonding

A covalent bond results when two atoms share electrons in such a way that each atom has an octet of electrons in the outer shell. Molecules have a three-dimensional shape that often determines their biological function.

Shape of Molecules

The shapes of molecules are necessary to the structural and functional role they play in living things.

Nonpolar and Polar Covalent Bonds

When the sharing of electrons between two atoms is fairly equal, the covalent bond is said to be nonpolar. The unequal sharing of electrons in a covalent bond results in a slightly negative charge and a slightly positive charge, resulting in a polar covalent bond.

Hydrogen Bonding

Polarity within a water molecule causes the hydrogen atoms in one molecule to be attracted to the oxygen atoms in other water molecules, forming a hydrogen bond.

2.3Chemistry of Water

The unique properties of water make it essential to the existence of life.

Properties of Water

The many hydrogen bonds that link water molecules help water absorb heat without a great change in temperature.Water has a high heat of vaporization because hydrogen bonds must be broken before water boils and water molecules vaporize. Water facilitates chemical reactions, both outside and within living systems. Molecules that attract water are said to be hydrophilic, while those that cannot attract water are said to be hydrophobic. Water flows freely and is able to adhere to polar surfaces.The stronger the force between molecules in a liquid, the greater the surface tension. Ice is less dense than liquid water, and therefore ice floats.

Acids and Bases

When water ionizes, it releases an equal number of hydrogen ions and hydroxide ions.

Acid Solutions (High H+ Concentrations)

Acids are substances that dissociate in water, releasing hydrogen ions.

Basic Solutions (Low H+ Concentration)

Bases are substances that either take up hydrogen ions or release hydroxide ions.

pH Scale

The pH scale is used to indicate the acidity or basicity of solutions. The pH scale ranges from 0 to 14.

Buffers and pH

A buffer is a chemical or a combination of chemicals that keeps pH within normal limits. In animals, the pH of body fluids is maintained within a narrow range, or else health suffers.

2.4 Organic Molecules

Organic molecules always contain carbon (C) and hydrogen (H). A functional group is a particular cluster of atoms that always behaves in a certain way. A monomer is a simple organic molecule that exists individually or can link with other monomers to form a polymer. Dehydration and hydrolysis reactions interconnect monomers and polymers.