Mediterranean diet and cognitive decline over time in an elderly Mediterranean population

Supplementary Table S1

Table S1 Multinomial logistic-regression-derived odds ratios(ORs)a and 95% confidence intervals (CI) of the change in MMSE by Mediterranean diet components, among 401 individuals. EPIC-Greece cohort.

Change in MMSE (-4 to -1) vs ≥ 0
OR (95% CI) per 1 SD* increment / p / Change in MMSE ≤-5 vs ≥0
OR (95% CI) per 1 SD* increment / p
Vegetables / 0.85 (0.61, 1.18) / 0.330 / 0.29 (0.14, 0.60) / 0.001
Legumes / 0.92 (0.71, 1.19) / 0.521 / 1.04 (0.66, 1.63) / 0.879
Fruits and nuts / 0.95 (0.74, 1.21) / 0.665 / 0.93 (0.60, 1.43) / 0.731
Diary products / 0.94 (0.72, 1.23) / 0.657 / 1.04 (0.66, 1.62) / 0.878
Cereals / 0.95 (0.71, 1.27) / 0.715 / 0.95 (0.57, 1.58) / 0.852
Meat / 1.14 (0.88, 1.48) / 0.333 / 1.12 (0.71, 1.77) / 0.631
Fish / 0.91 (0.72, 1.15) / 0.418 / 1.03 (0.71, 1.51) / 0.869
Alcoholb / 0.75 (0.44, 1.27) / 0.278 / 0.56 (0.23, 1.38) / 0.208
Ratio of monounsaturated to saturated lipids / 1.01 (0.75, 1.35) / 0.970 / 1.34 (0.84, 2.15) / 0.218

a Adjusted for gender, age (<70, 70-74, ≥75 years, categorically), years of education (0-5, 6-11,12, ≥12 years, categorically), BMI (<25, 25-30, ≥ 30 kg/m2, categorically), physical activity expressed in MET-hours per day (sex-specific quintiles, ordered),smoking (never, ex, and current smokers of tobacco quantity equivalent to <15 and ≥ 15 cigarettes/day, categorically), diabetes (Yes, No), hypertension (Yes, No), cohabiting (Yes, No)and total energy intake (sex-specific quintiles, ordered) as well as mutually adjusted by all the indicated dietary variables that compose the Mediterranean diet score.

b 10-50 vs <10 or >50 g/day from men and 5-25vs <5 or >25 g/day for women.

*SD: standard deviation of consumption over all subjects (n=401).