* Supplemental Appendix. Detailed List of Tabulated Studiesin Figure 2, As Found in Reference

* Supplemental Appendix.Detailed list of tabulated studiesin Figure 2, as found in Reference [10]. These are numbered according to their order in Figure 2.

1-A. Rossi, G. Bersani, G. Ricci, et al. Intragastric balloon insertion increases the frequency of erosive esophagitis in obese patients ObesSurg, 17 (2007), pp. 1346–1349

2-R. Forlano, A.M. Ippolito, A. Iacobellis, et al. Effect of the BioEntericsintragastric balloon on weight, insulin resistance, and liver steatosis in obese patients GastrointestEndosc, 71 (2010), pp. 927–933

3-A. Loffredo, M. Cappuccio, M. De Luca, et al. Three years experience with the new intragastric balloon, and a preoperative test for success with restrictive surgery ObesSurg, 11 (2001), pp. 330–333

4-M.L. De Castro, M.J. Morales, V. Del Campo, et al. Efficacy, safety, and tolerance of two types of intragastric balloons placed in obese subjects: a double-blind comparative study ObesSurg, 20 (2010), pp. 1642–1646

5-C.-M. Tai, H.-Y. Lin, Y.-C. Yen, et al. Effectiveness of intragastric balloon treatment for obese patients: one-year follow-up after balloon removal ObesSurg, 23 (2013), pp. 2068–2074

6-A. Genco, M. Lorenzo, G. Baglio, et al. Does the intragastric balloon have a predictive role in subsequent LAP-BAND® surgery? Italian multicenter study results at 5-year follow-up SurgObesRelat Dis, 10 (2014), pp. 474–478

7-M. Konopko-Zubrzycka, A. Baniukiewicz, E. Wroblewski, et al. The effect of intragastric balloon on plasma ghrelin, leptin, and adiponectin levels in patients with morbid obesity J ClinEndocrinolMetab, 94 (2009), pp. 1644–1649

8-R.A. Mazure, G. Salgado, P. Villarreal, et al. Intragastric balloon and multidisciplinary team NutrHosp, 24 (2009), pp. 282–287

9-S. de Goederen-van der Meij, R.G.J.M. Pierik, M. Oudkerk Pool, et al. Six months of balloon treatment does not predict the success of gastric banding ObesSurg, 17 (2007), pp. 88–94

10-L. Angrisani, M. Lorenzo, V. Borrelli, et al. Is bariatric surgery necessary after intragastric balloon treatment? ObesSurg, 16 (2006), pp. 1135–1137

11-F. Donadio, L.F. Sburlati, B. Masserini, et al. Metabolic parameters after BioEntericsIntragastric Balloon placement in obese patients J Endocrinol Invest, 32 (2009), pp. 165–168

12-E.M.H. Mathus-Vliegen, G.N.J. TytgatIntragastric balloon for treatment-resistant obesity: safety, tolerance, and efficacy of 1-year balloon treatment followed by a 1-year balloon-free follow-up GastrointestEndosc, 61 (2005), pp. 19–27

13-C. Giardiello, A. Borrelli, E. Silvestri, et al. Air-filled vs water-filled intragastric balloon: a prospective randomized study ObesSurg, 22 (2012), pp. 1916–1919

14-N. Crea, G. Pata, D. Della Casa, et al. Improvement of metabolic syndrome following intragastric balloon: 1 year follow-up analysis ObesSurg, 19 (2009), pp. 1084–1088

15-E.M.H. Mathus-Vliegen, R.I. Eichenberger Fasting and meal-suppressed ghrelin levels before and after intragastric balloons and balloon-induced weight loss ObesSurg, 24 (2014), pp. 85–94

16-M.G. Farina, R. Baratta, A. Nigro, et al. Intragastric balloon in association with lifestyle and/or pharmacotherapy in the long-term management of obesity ObesSurg, 22 (2012), pp. 565–571

17-A. Genco, S. Balducci, V. Bacci, et al. Intragastric balloon or diet alone? A retrospective evaluation ObesSurg, 18 (2008), pp. 989–992

18-A. Genco, M. Cipriano, A. Materia, et al. Laparoscopic sleeve gastrectomy versus intragastric balloon: a case-control study SurgEndosc, 23 (2009), pp. 1849–1853

19-R.M. Tayyem, C. Obondo, A. Ali Short-term outcome and quality of life of endoscopically placed gastric balloon and laparoscopic adjustable gastric band Saudi J Gastroenterol, 17 (2011), pp. 400–405

20-A. Genco, M. Lorenzo, G. Baglio, et al. Does the intragastric balloon have a predictive role in subsequent LAP-BAND® surgery? Italian multicenter study results at 5-year follow-up SurgObesRelat Dis, 10 (2014), pp. 474–478

21-H. Alfalah, B. Philippe, F. Ghazal, et al. Intragastric balloon for preoperative weight reduction in candidates for laparoscopic gastric bypass with massive obesity ObesSurg, 16 (2006), pp. 147–150

22-U.B. Dogan, Y. Gumurdulu, M.S. Akin, et al. Five percent weight lost in the first month of intragastric balloon treatment may be a predictor for long-term weight maintenance ObesSurg, 23 (2013), pp. 892–896

23-F. Mion, B. Napoleon, S. Roman, et al. Effects of intragastric balloon on gastric emptying and plasma ghrelin levels in non-morbid obese patients ObesSurg, 15 (2005), pp. 510–516

24-M. Nikolic, M. Boban, N. Ljubicic, et al. Morbidly obese are ghrelin and leptin hyporesponders with lesser intragastric balloon treatment efficiency: ghrelin and leptin changes in relation to obesity treatment ObesSurg, 21 (2011), pp. 1597–1604

25-O. Khan, S. Irukulla, N. Sanmugalingam, et al. Simultaneous intra-gastric balloon removal and laparoscopic sleeve gastrectomy for the super-super obese patients–a prospective feasibility study ObesSurg, 23 (2013), pp. 585–587

26-Y. Peker, E. Durak, U. OzgurbuzIntragastric balloon treatment for obesity: prospective single-center study findings Obes Facts, 3 (2010), pp. 105–108

27-H. Coskun, O. Bostanci Assessment of the application of the intragastric balloon together with sibutramine: a prospective clinical study ObesSurg, 20 (2010), pp. 1117–1120

28-M.D. Frutos, M.D. Morales, J. Lujan, et al. Intragastric balloon reduces liver volume in super-obese patients, facilitating subsequent laparoscopic gastric bypass ObesSurg, 17 (2007), pp. 150–154

29-D. Stimac, S.K. Majanovic, T. Turk, et al. Intragastric balloon treatment for obesity: results of a large single center prospective study ObesSurg, 21 (2011), pp. 551–555

30-C. Spyropoulos, E. Katsakoulis, N. Mead, et al. Intragastric balloon for high-risk super-obese patients: a prospective analysis of efficacy SurgObesRelat Dis, 3 (2007), pp. 78–83

31-T.S. Papavramidis, V. Grosomanidis, P. Papakostas, et al. Intragastric balloon fundal or antral position affects weight loss and tolerability ObesSurg, 22 (2012), pp. 904–909

32-T.S. Papavramidis, V. Grosomanidis, P. Papakostas, et al. Intragastric balloon fundal or antral position affects weight loss and tolerability ObesSurg, 22 (2012), pp. 904–909 (same as 31).

33-F. Puglisi, N. Antonucci, P. Capuano, et al. Intragastric balloon and binge eating ObesSurg, 17 (2007), pp. 504–509

34-F. Puglisi, N. Antonucci, P. Capuano, et al. Intragastric balloon and binge eating ObesSurg, 17 (2007), pp. 504–509 (same as 33).

35-K. Kotzampassi, E. EleftheriadisIntragastric balloon as an alternative restrictive procedure for morbid obesity Ann Gastroenterol, 19 (2006), pp. 285–288

36-W.N. Abdel-Salam, M. Bekheit, K. Katri, et al. Efficacy of intragastric balloon in obese Egyptian patients and the value of extended liquid diet period in mounting the weight loss J LaparoendoscAdvSurgTechn Part A, 23 (2013), pp. 220–224

37-K. Deliopoulou, A. Konsta, S. Penna, et al. The impact of weight loss on depression status in obese individuals subjected to intragastric balloon treatment ObesSurg, 23 (2013), pp. 669–675

38-K. Deliopoulou, A. Konsta, S. Penna, et al. The impact of weight loss on depression status in obese individuals subjected to intragastric balloon treatment ObesSurg, 23 (2013), pp. 669–675 (same as 37).

39-K. Kotzampassi, A.D. Shrewsbury, P. Papakostas, et al. Looking into the profile of those who succeed in losing weight with an intragastric balloon J LaparoendoscAdvSurgTechn Part A, 24 (2014), pp. 295–301

40-G. Lopez-Nava, M.A. Rubio, S. Prados, et al. BioEntericsintragastric balloon (BIB). Single ambulatory center Spanish experience with 714 consecutive patients treated with one or two consecutive balloons ObesSurg, 21 (2011), pp. 5–9

41-K. Kotzampassi, V. Grosomanidis, P. Papakostas, et al. 500 intragastric balloons: what happens 5 years thereafter? ObesSurg, 22 (2012), pp. 896–903

42-S. Gottig, M. Daskalakis, S. Weiner, et al. Analysis of safety and efficacy of intragastric balloon in extremely obese patients ObesSurg, 19 (2009), pp. 677–683

43-S. Gottig, R.A. Weiner, M. Daskalakis Preoperative weight reduction using the intragastric balloon Obes Facts, 2 (Suppl 1) (2009), pp. 20–23

44-M. Saruc, D. Boler, M. Karaarslan, et al. Intragastric balloon treatment of obesity must be combined with bariatric surgery: a pilot study in Turkey Turk J Gastroenterol, 21 (2010), pp. 333–337