sLORETA workshop

Course Description

The course will center on the functional tomographic method known as standardized low resolution brain electromagnetic tomography (sLORETA). The lessons comprise: (1) introduction to LORETA/sLORETA (2) review of frequency domain analysis techniques (3) statistical methods of analysis (for EEG/ERP and LORETA images) (4) software practice. The emphasis will be on software practice.

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Program

Day I:

Morning session

- Introduction: EEG/ERP source localization, LORETA/sLORETA, validation, applications.

- Getting started with sLORETA I:

* learning about sLORETA options

* preparing electrode coordinate files

* preparing transformation matrix

* inspecting data with the sLORETA explorer

* Quantitative neuroanatomy in sLORETA based on the Talairach atlas

* transforming EEG/ERP data into sLORETA

Lunch

Afternoon session

- Some elements of frequency domain analysis

- Getting started with sLORETA II:

* computing EEG cross-spectra

* exploring EEG cross-spectra

* transforming EEG cross-spectra data into LORETA

- A survey of "Utilities"

Day II

Morning session: ERP data (time domain)

- The “when” question: Exploring and confirming moments in time of significant difference in brain processing between two conditions/tasks (ERP data). Statistics based on scalp measurements: Topographic analysis of variance (TANOVA) using non-parametric randomization.

- The “where” question: Given a significant moment in time (“when”), determine which parts of the cortex are responsible for the differential information processing.

Lunch

Afternoon session: EEG data (frequency domain)

- The “which-frequency” question: Exploring and confirming the frequency bands of significant difference in brain processing between two conditions/tasks.

- The “where” question: Given a significant frequency band, determine which parts of the cortex are responsible for the observed differences.

- General open discussion

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Minimal Requirements

You must bring your own Laptop PC running Win98 or higher, CD ROM drive, 10 GB free hard disk space, 512 MB RAM, 1024x768 graphics with 32768 colors supporting OpenGL.

You must download and install the software before the workshop takes place. If the program does not execute properly, you will not be able to use your laptop during the training course.

You must go through the Tutorial before the workshop takes place, otherwise, you might be responsible for slowing down the presentation to the extent that some major parts of the program will not be explained.

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Lecture style and goals

You are encouraged to interact and interrupt the lectures with comments and questions at any moment. The goals are that you gain an understanding of the principles of the methods, and that you be fully capable of properly using the offered software tools on your own.