PartA
Haveyou ever taken a medication that yourdoctor warned you would not take effect forafewdays?Inthisactivity,youwillinvestigatewhythat isthecase.
ConsidertheallergymedicineSneeze-B-Gone.Theregularadultdoseis20milligrams.Aswithallmedicines,thebodygraduallyfiltersSneeze-B-Goneoutofthebloodstream.Therateat which the medicine is filtered outis called theflush rate. For Sneeze-B-Gone, theflushrateis30%.Inotherwords, 24hoursafterthe pillistaken,30%ofSneeze-B-Gonehasflushedoutofthebody.
1.If30%of Sneeze-B-Gone hasflushed out of thebody after 24 hours,what percentofSneeze-B-Goneremains?
2.Useyourcalculator’srecursionfeaturetofillinthetablebelow,assumingthatanadult istakingone20-milligramdoseperday.
3.At what valuedoes the amount ofSneeze-B-Goneinthebloodstreamleveloff?How manydays does ittake for that tohappen?
4.Whattypeoffunctioncould modeltheamountofSneeze-B-Goneinthebloodstreamasafunction oftime?Explainyourchoice.
5.WhatwouldyouexpectagraphoftheamountofSneeze-B-Goneinthebloodstreamasafunction oftimetolooklike?Explainyourprediction.
6.Recallthatthegeneralformforexponentialdecayfunctionsisy=a(b)x,where arepresentsthestartingamountofthesubstanceandbrepresentsthe rate ofdecay. Fora20-milligram doseanda30%flushrate,whatexponentialfunctioncoulddescribetheamountofSneeze-B-Gonein thebloodstream(y)asafunctionoftime (x)?(Donotforgetthatbrepresentsthepercentof Sneeze-B-Gonethatremains inthebloodstream.)
7.Since the patient didnot begintaking themedicine untilDay 1, adjustyour function rulebysubtracting1fromtheexponent.Graphthefunctiononyourgraphingcalculator. Sketchyourgraphanddescribeyourviewingwindow.
8.Iftime (x)isgivenintermsofthenumberofdays,whathappenstotheamountofSneeze-B-Gonein the patient’sbloodstream at the start of Day2when the patienttakesasecondpill?Howdoesthisaffectthegraph?
9.Use what you learned aboutstep and piecewise functions in previous activitiesto restrictthedomainofthegraph.Sketchyournewgraph.
10.For Day2,enterthe functiony 340.7x1 intoyourcalculator. Whatdo theconstants34,0.7,and2represent?Sketchthenew graph.
11.Basedonthe functions for Day1 andDay2, write a function fromthe datain your tableforDay3anda functionforDay4.
12.Graphbothofthesenewfunctions.Whatpatternsdoyounotice?Whatdoyouexpect thegraphforDay5tolooklike?
13.TestyourpredictionbywritingafunctionforDay5.
14.REFLECTION:Assumethepatienttakes20milligramsofSneeze-B-Goneeveryday.IfyouextendthegraphtoDay20orbeyond,whatwouldtheminimumamountofSneeze-B-Goneinthebloodstreambe?Themaximumamount?
PartB
1.Supposeapatientrequiresa 30-milligramdoseofSneeze-B-
Gone.Usehomescreenrecursiononyour calculator to fillinthetable.
2.At what valuedoes the amount ofSneeze-B-Goneinthebloodstreamleveloff?How manydays does ittake for that tohappen?
3.Howdoesthefunction ruleforthe20-milligramdosechangefora
30-milligramdose?Writethenew functionrule fortheportionofthegraphbetween Day1 and Day2.
4.Howdoyouthinkthosechangeswouldaffectthegraphofthenew function rule?
5.Useyourgraphingcalculatortotest yourprediction.Sketchyourgraph.
6.WhentheamountofSneeze-B-Goneinthebloodstreamlevelsoffforapatienttakinga30-milligramdailydose,whataretheminimumandmaximumamountsofSneeze-B-Goneinthebloodstreamwithinagivenday?
7.Supposeapatientrequiresa40-milligram doseof Sneeze-B-Gone.Basedon whatyouhaveobservedsofar,whatwouldyouexpectthefunctionruleandgraphtolooklike?
8.Userecursiononyour calculatortofill inthe table.
9.At what valuedoes the amount ofSneeze-B-Goneinthebloodstreamleveloff?How manydays does ittake for that to happen? You mayneedtoextendthe valuesinthe table.
10.Howdoesthefunctionruleforthe30-milligramdosechangewitha40-milligramdose?Writethe new function rule for theportionofthegraphbetween Day 1 andDay2.
11.Howdoyouthinkthosechangeswouldaffectthegraphofthenew function rule?
12.Useyourgraphingcalculatortotestyourprediction.Sketchyourgraph.
13.WhentheamountofSneeze-B-Goneinthebloodstreamlevelsoffforapatienttakinga40-milligramdose,whataretheminimumandmaximumamountsofSneeze-B-Gone inthebloodstreamwithinagivenday?
14.REFLECTION:HowdoesanincreaseindoseaffecttheamountofSneeze-B-Goneinthebloodstreamwhenthe amountlevelsoff?
15.Fillin thetable below.What relationshipsdo younotice?
Dose / FlushRate / Leveled-offAmount / DoseFlushRate20
30
40
16.REFLECTION:If you werea doctor ornurse and youknew that apatientneeded tohaveabout100milligramsofSneeze-B-Goneinhisbloodstreamforthemedicinetobeeffective,whatdosewouldyouprescribe?Explainyourdecision.
17.EXTENSION:Anewcholesterol-loweringmedicinehasaflushrateof50%.Fora
20-milligramdoseofthismedicine,howdothefunctionrulesandgraphcomparetothoseforthe 20-milligramdoseofSneeze-B-Gone witha flushrate of30%?Use yourgraphingcalculatortoinvestigate.Presentyourworktotheclass.