Curriculum Vitae
Hoda youssef Hassan Huossien
Name: Hoda youssef Hassan Huosien
Family Name: Hassan Forename: Hoda
Nationality: Egyptian
Sex: Female
Date of Birth: December 5, 1948 Place of Birth Aswan, Egypt
Marital Status: Married
Home Address: Nile Street Alexan Appartment No. 1, 13th Flat
Assiut, Egypt.
Telephone Number: (2088)-2328404 Mobile: 01224775986
Fax Number (2088)-332776
Work Address: Departement of Medicinal Chemistry, Faculty of
Pharmacy, AssiutUniversity, Assiut, Egypt.
Current Status: Associate Professor
Languages:
English: Fluent written and spoken
E-mail:,
Education:
1-1972: B.Sc in pharmaceutical sciences, AssiutUniversity with grade excellent with degree of honor.
2-1977: M.Sc. Pharm. Sci. (Pharmaceutical Medicinal Chemistry)
Faculty of Pharmacy, AssiutUniversity, Assiut, Egypt.
Title of the thesis:
Synthesis of new pyridyl acrylic acid derivatives of potential antiprotozoal activity
3-1983: Ph.D.(Pharmaceutical Medicinal Chemistry)
Faculty of Pharmacy, AssiutUniversity, Assiut, Egypt.
Title of the thesis
Synthesis of nitropyridine derivatives as active agents against certain microbes and parasites
Courses as Prerequisite to M.Sc. and Ph.D
1-Instrumental analysis
2-Mathematics and Statistics
3-Physical chemistry
4-Laboratory safety and waste disposal
5-Advanced medicinal chemistry (1)
6-Advanced medicinal chemistry (2)
7-Introduction for synthesis of medicinal agents
8-Advanced pharmaceutical analysis
9-Practical bases of chemical processes and reactions
Studied Abroad
1997 Postdoctoral fellowship for six months in KyotoUniversity with Prof. Nakagawa
Research Interest
Design and synthesis of organic compounds of potential biological activities.
Design, synthesis and investigation of chelating agents.
Prodrug and chemical delivery system.
Studying docking, pharmacophore searching and alignments using computer software (E.g. MOE program).
Teaching:
Teaching of of organic Chemistry First year students AssiutUniversity, (1983- 1984)
Teaching of Pharmaceutical Medicinal Chemistry for third and fourth year students AssiutUniversity.
Teaching of of organic Chemistry Second year students El Minia University, (2000- 2001)
Teaching of Pharmaceutical Medicinal Chemistry for third and fourth year students
El Minia University (2001- 2005).
Teaching of Drug design Medicinal Chemistry for Second, third and fourth year students AlAzharUniversity (2004- 2008).
Supervision on Scientific thesis:
(9 master thesis ) Six are finished and (2 Ph. D thesis all are finished).
Experience Record:
1-Demonstrator from 1/3/1973 of undergraduate courses of pharmaceutical medicinal and organic chemistry as well as analytical pharmaceutical chemistry.
2-Associate lecturer from 7/11/1977 in Faculty of Pharmacy Assiut University, Assiut Egypt
3-Lecturer from 22/5/1983, teaching Organic, pharmaceutical medicinal chemistry to under- and post-graduate students, co supervisor of M. Sc and Ph.D. Thesises.
4-Associate Professor from 12/8/1990, teaching pharmaceutical medicinal chemistry to under- and post-graduate students, co supervisor of M. Sc and Ph.D. Thesises.
5- from 5-12-2008
List of Publication
1- Synthesis and spectroscopic study of some 3- Nitro pyridines
Adel F. Youssef; Hassan H. Farag, H. Youssef
Indian J. of Chemistry, Vol. 15B, 190-191 (1977).
2- Synthesis and biological Activity of 2-methyl-3- Nitro pyridine derivatives
H. H. Farag, A. H. Abdel-Aleem, A. F. Youssef, H. youssef, H. Abdel-Mageed and A. Abdel- Hafez
Egypt. J. Pharm. Sci., Vol. 22, 207-221 (1981).
3-Synthesis of 2-Methyl-3-Nitro-6-Substituted Pyridines as Active Agents AgainstCertain Microbes and Parasites.
A. F. Youssef, H. H. Farag,H. youssef,S.H.Ahmed and A.Abdel-Hafez
XVIII Egytian Conference of Pharmaceutical Sciences, Cairo 24-27 Feb.(1984) Abstracts p.157.
4- Synthesis of Some 2,7-Diazabicyclo(4.1.0) Hepta-3-ene Derivatives with Analgesic and Anticoccidial Activity.
H. H. Farag, A. H. Abdel-Aleem, , H.Y. Hassan, H.A.Hemaiat-Allah,R.A.Abdel-Aaland A.M.EL-Badr.
Bull. Pharm. Sci., AssiutUniversity, Vol. 9(2) pp.105-118 (1986).
5-Spectrophotometric determination of some dibenzazepine drugs by electrophilic coupling . S.A.Hussein, M.E.El-Kommos, H.Y.Hassan and A-M.I.Mohamed,Talanta , Vol.36 (9), 941-944 ( 1989 ).
6-Spectrophotometric determination of some dibenzazepines with picryl chloride. S.A.Hussein , A-M.I.Mohamed and H.Y.Hassan,Talanta, Vol. 36(11), 1147-1149 ( 1989 ).
7-Utility of certain p-acceptors for the spectrophotometric determin-ation of isoniazid. H.Y.Hassan , A-M.I.Mohamed and F.A.Mohamed, Anal.Letters, Vol.23 (4), 617-625 ( 1990 ).
8-Use of 7,7,8,8-tetracyanoquinodimethane for spectrophotometric determination of certain local anaesthetics and procainamide HCl.
A-M.I.Mohamed , H.Y.Hassan , H.A.Mohamed and S.A.Hussein, J.Pharm. Biomed.Anal., Vol.9(7), 525-530 ( 1991 ) .
9- Spectrophotometric determination of some dibenzazepines. H.A. Mohamed , H.Y.Hassan , A-M.I.Mohamed and S.A.Hussein, Anal.Letters,Vol.25(1), 63-71 ( 1992 ) .
10- Studies on synthesis of some quinazolinones bearing different heterocyclic moieties with expected biological activity
Y Hassan, AA Ismaiel, HAH El-Sherief H
Eur J Med Chem 26, 743-748 (1991)
11-Synthesis of ChelatingOxazole Derivatives with Potential Biological Activity
M. M. Sheha,Hoda Y. Hassan,A. F. Youssef,H. I.EL-Betar and S.M.Abdalla
Egypt. J. Pharm. Sci., Vol. 34, 711-730 (1993).
12-Design and synthesis of some new 1H-1,2,4-triazoles of potential anti inflammatory and analgesic activities.
Hoda Y. Hassan, Abdel-Nasser El-Shorbagi, Nawal A. El-Koussi and Ahmed O. Abdel Zaher
Bull. Pharm. Sci., AssiutUniversity, Vol. 17, Part 1, (1994), 27.
13-Synthesis and investigation of MAO inhibitors hydrazones of potential brain-specific delivery.
Nawal A. El-Koussi, Hoda Y. Hassan and Hassan H. Farag
Bull. Pharm. Sci., AssiutUniversity, Vol. 20, Part 2, (1997), 155.
16-Synthesis and investigation of certain 3(5)-substituted-1,2,4-triazol-5(3) carboxylic acid derivatives.
Atef A. Abd-El-Hafez, Hamdy M. Mohamed, Hoda Y. Hassan, Gamal S. El-Karamany, Nawal A. El-Koussi and Adel F. Youssef
Bull. Pharm. Sci., AssiutUniversity, Vol. 20, Part 1, 47 (1997).
17-SAR of HIV Protease Inhibitors: P2 and P3 Structural Requirments
Mahmoud M. Sheha, Shingo Nakata, Hiroshi Enomoto,Tooru Kimura, Tsutomu Mimoto, Naoka Hattori, Nadia M. Mahfouz , Hoda y. Hassan, Adel F. Youssef, Kenchi Akajii and Yoshiaki Kiso
Peptide Chemistry: M. Ohno (Ed.) 349-352 (1994)
18-Synthesis and antimicrobial activity of pyridine bearing thiazoline and thiazolidinone moieties.
Hoda Y. Hassan, Nawal A. El-Koussi and Zeinab S. Farghaly; Chem. Pharm. Bull Vol. 46 No. 5, 863 (1998).
19-Synthesis of certain nitropyridine derivatives bearing 2- thiazolyl hydrazines with expected monoamine oxidase inhibitory activity.
Hoda Y. Hassan,
Bull. Pharm. Sci., AssiutUniversity, Vol. 22, Part 1, 35- 45 (1999).
20-Synthesis and Chelating Properties of Substituted Formyl Pyridine Thiosenicarbazones of Potential Biological Activity
Hoda Y. Hassan,
Bull. Pharm. Sci., AssiutUniversity, Vol. 22, Part 1, 97-108 (1999).
21- Synthesis of Di-and Tripeptide Analogs containing – Ketoamide as a New Core Structure for Inhibition of HIV-1 Protease
Mahmoud M. Sheha, Nadia M Mahfouz , Hoda Y.Hassan, Adel F. Youssef, Tsutoma Mimotob and Yoshiaki Kiso
Eur. J. Med. Chem. 35, 887-894 (2000)
22- Synthesis and antimicrobial activity of certain nitropyridine derivatives
Nawal A. El-Koussi, Samia G. Abdel Moty and Hoda Y. Hassan
Bull. Fac.Sci., AssiutUniversity, 33(2-B), (2004), 9.
23 - Synthesis of 5-phenyl-1-(3-pyridyl)-1H-1,2,4-triazole-3-carboxylic acid
derivatives of potential anti-inflammatory activity.
Safoat Rabea, Nawal-A. El-Koussi, Hoda Y. Hassan and Tarek A. El-Fadel.
Arch. Pharm. Chem.Life Sci., 339, (2006), 7.
24- Fluorinated 1,2,4-triazolo[1,5-a]pyrimidine-6-carboxylic acid derivatives as
antimycobacterial agents.
Hamdy M. Abdel-Rahman, Nawal A. El-Koussi, Hoda Y. Hassan
Arch. Pharm. Chem.Life Sci., 342, (2009) 94.
Solution-Phase Synthesis of Small Shiff Bases
Combinatorial Library with Potential Antitubercular
Activity.
Der Pharma Chemica,2009,1(2), 1-13.
Pharmacophoric model building for antitubercular activity
of the individual Schiff bases of small combinatorial
library.
European Journal of Medicinal Chemistry 2010, 45, 1098-1106
25-Synthesis of substituted dihydropyrimidines as hypotensive agents
Salah A. Abdel-Aziz, Nawal A. El-Koussi, Hoda Y. Hassan , Adel F. Youssef , Magda M. Yousri.
Bull. Pharm. Sci., AssiutUniversity, Vol. 34, Part 2, (2011), 159.
26- Synthesis, biological investigation and molecular docking study of
N-malonyl-1,2-dihydroisoquinoline derivatives as brain specific and
shelf-stable MAO inhibitors
Mohammed K. Abd El-Gaber , *, Hoda Y. Hassan , Nadia M. Mahfouz , Hassan H. Farag and Adnan A. Bekhit
European Journal of Medicinal Chemistry 93 (2015) 481e491
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