NFSC 440 - ADVANCED HUMAN NUTRITION

Fall 2005

Instructor: Katie Silliman, Ph.D., R.D.

Office: Holt Hall 104Phone: 898-6245

Office Hours: Tuesday 2 – 4 PM, Wednesday 1-2 PM, Thursday 2 - 4 PM or by appointment

Prerequisites: NFSC 240 and Chem 350 or Chem 451

E-mail:

Texts: Advanced Nutrition and Human Metabolism, 4th ed., by Gropper, Smith + Groff (REQUIRED)

Supplemental Reader available at Mr. Kopy (REQUIRED) – ask for packet #82

WEB SITE: - this web site will allow you to read the DRI reports, just type “dietary reference intake” in the search window.

Recommended References:

1. A biochemistry textbook

2. A medical physiology textbook

3. For those needing to review biochemistry check out the WEB SITE:

Grading: 3 exams ------300 points

Final (comprehensive) ------150

Internet Product Ad or Article ------10

Outline of product ------20

Critique of claims

made for supplement/CAM ------100

------

580 points

Assignments are due at the beginning of class. Assignments turned in late will have 5 % of the points deducted for EACH day late.

OBJECTIVES:

  • To provide detailed information on the structure, function, digestion, transport, storage, and metabolism of the nutrients.
  • To delineate key metabolic pathways in the utilization of macronutrients as well as the interrelationships among nutrients in metabolism.
  • To have a basic understanding of the physiology of exercise.
  • To identify nutritional requirements (energy and nutrients) and significant food sources of macro- and micro-nutrients.
  • To interpret the basis of human nutrient deficiencies and excesses.
  • To demonstrate comprehension and interpretation of nutrition-related research as reported in scientific publications. This will be accomplished by classroom discussion of a research article and the completion of a written critique of claims made for alternative nutrition and herbal therapies.
  • To provide a basis for evaluation of current and recommended nutritional practices.
  • To become familiar with complementary and alternative nutrition, herbal therapies, and dietary supplements.
  • To become familiar with the role genetics plays in nutrition.
  • To develop interpersonal communication skills and to learn to work effectively as a team member by doing collaborative work.
  • To become proficient at gathering information using current information technologies.

TENTATIVE COURSE SCHEDULE

WEEKTOPICREADINGS

1Overview of the cell1-21; 53-69;

Strategy of metabolic oxidation; ATP281-290

regeneration (riboflavin, niacin)

2Carbohydrates72-101;

Carbohydrate metabolism and Intermediary291-301;

metabolism (pantothenic acid, biotin)243-250;

Fuel use during exercise257-258

3Fiber (Take home quiz)108-120

4Lipids128-162

Lipoproteins and cholesterol

EXAM I - THURS. SEPT. 15th

5 Lipids (Cont.)

Oxidation and synthesis (thiamin)275-281

Product AD or Article Due - THURS. SEPT. 22nd

6Diet and Heart Disease147-151;166-167

7Protein and amino acids172-218;

Protein metabolism (B-6)316-321;

Nutrigenomics168-171;322-324

8Protein quality and requirements218-223; 551-565

Interpreting nutrition research

EXAM II - THURS. OCT. 13th

9Integration and regulation of metabolism230-243; 226-229

10Etiology of Obesity70-71; 161-165; 520-522;

Alcohol metabolism101-105

Outline of Product and References Due -

TUES. OCT. 25th

11Water-soluble vitamins (C, folic acid, B-12)260-273; 301-315

12Fat-soluble vitamins325-367

EXAM III - THURS. NOV. 10th

13Fat-soluble vitamins (cont.)

14Minerals378-407

Critique Due - THURS. DEC. 1st

(oral presentations - THURS)

15Minerals – cont.417-484

(oral presentations - TUES)

FINAL EXAM TUES. DEC. 13th from 2-3:50 pm