A.A.2016/2017
INSEGNAMENTO: Pathology and laboratory diagnosis.
Educational objectives / Microbiology and clinical microbiology:
To know the meaning of infection and infectious disease.To know the most important microorganisms responsible of the main infectious diseases.To know the principal techniques regarding antisepsis, disinfection and sterilization, and the means to prevent infections.To know how to take, to transport and to preserve a sample for microbiological diagnosis.To know the main concepts of the antibiotic therapy.To know the main infective complications linked to nursing procedures.
To know the conditions promoting the rise up of infections and the prevention options.
Clinical pathology and transfusional medicine:
Acquire the knowledge necessary for a correct application of diagnostic and laboratory tests for disease prevention, assistance to the patient and health education.
Immunology:
This course is aimed at providing abasic understanding of the cellular and molecular basis of immuneresponsivenessand the roles of the immune system in both maintaining health and contributing to disease.
General Pathology and pathophysiology:
Knowledge of environmental agents (chemical, physical, biological) of damage, cell and tissue damagemechanisms and inflammatory response involved in human disease development.
Basements of molecular mechanisms involved in tumour initiation and progression .
The student should acquire the basic knowledges of pathophysiology of organ failure.
Particularly the student should be able to analytically illustrate the pathophysiology of the cardiovascular, liver and respiratory diseases and diabetes.
Contents / Microbiology and clinical microbiology:
Short accounts on the importance of microorganisms and their classification.
Host-parasite interaction and ways of infection.
General characters of bacteria and viruses and their moltiplication.Main concepts of microbiological diagnosis.Prevention of infections: antisepsis, disinfection, sterilization; vaccines and sera.Chemotherapics and antibiotics; importance of resistance.Main concepts on the pathologies determined by the most important bacteria and viruses.Short accounts on the infections caused by fungi and parasites.
Clinical pathology and transfusional medicine
Variability and test evaluation
Specimens collection
Plasma proteins
Renal function and main renal syndromes
Urinanalysis
Electrolytes
Cardiovascular markers
Clinical pathology of the liver
Coagulation disorders
Hemocrome tests and related disorders.
Icterus
Blood transfusion therapy
Immunological tests and acute phase proteins
Immunology:
The course will introduce the students to the fundamental concepts of modern immunology. The course will cover structure and function of the immune system, antigens and antibodies, complement, genetic basis of the immune response, humoral and cellular immunity, immunological tolerance, organ and tissue transplantation, allergy and autoimmunity.
General Pathology and pathophysiology:
Cell growth adaptation: hypertrophy, hyperplasia, atrophy, dysplasia, metaplasia.
Cell death: necrosis, apoptosis.
Environmental pathology – physical causes: radiation, high and low pressure diseases, hyper/hypothermia. Environmental hazards: drug abuse, smoke, pharmaceutical drugs
Acute and Chronic inflammation. Wound healing Tumours: concept of benignity and malignancy, cancer development (initiation, promotion, progression), aetiology, classification.
The fever. Vascular pathology: arterial hypertension and hypotension, shock, hemorrhages, atherosclerosis, thrombosis, embolism, heart attack. Coronary disease, ischemic cardiomyopathy (stable and unstable angina, myocardial infarction), rheumatic illness. Pathophysiology of the respiratory system (asthma, emphysema, bronchiectasis, chronic obstructive pulmonary disease…) .Liver diseases: acute and chronic insufficiency, encephalopathy, jaundices, alcoholic hepatitis, steatosis and cirrhosis, portal hypertension, ascites. Neurodegenerative diseases. Diabetes type I and II.
Text: / Microbiologyand clinical microbiology:
Materials online on Campusnet.
Principi di microbiologia clinica (Lanciotti, Casa Editrice Ambrosiana, Milano).
Clinical Pathology and trasfusional medicine:
Materials online on Campusnet.
Immunology:
Quaglino, Cavallo, Forni. Le difese immunitarie. Piccin editore
General Pathology and pathophysiology:
Patologia e Fisiopatologia Generale”. Per i corsi di Laurea in Professioni Sanitarie (G.M. Pontieri, Piccin ed.)
Prerequisiti (conoscenze di base che lo studente deve possedere per accedere al corso, nel caso non siano previste indicare “NESSUNA”) / NONE