HUMAN PHYSIOLOGY – BSN HS2410 Fall 2012

Human Physiology studies functional processes within our bodies that maintainhomeostasis, an optimal internal environment to support cell life. These processes, achieved by coordinated function of each system, maintains cellular integrity by neural and hormonal control mechanisms. We will explain, integrate and synthesize information rather than simply describe these processes, so that you will achieve a working knowledge of physiology, not just a memory bank of physiological facts. Our objective is to help you acquire an understanding of and an appreciation for organ function and control which will serve you in your clinical studies. E.H. Starling, a famous physiologist of the early 20th century, once remarked, "The physiology of today is the medicine of tomorrow." We will make every effort to demonstrate that this statement is true while sharing with you our knowledge of and enthusiasm for the subject of physiology.

COURSE DIRECTOR: Dr. Raymond E. Shepherd

The Course Director is directly responsible for the supervision and administration of HLSC 2410. Any policy or schedule changes will be formally announced by Dr. Shepherd by mass email to the class.

Members of the teaching staff are:

INSTRUCTORBUILDING OFFICE PHONE emailaddress

Raymond E. Shepherd, PhD (Director)

Jason D. Gardner, PhD (Co-Director)MEB

Jessica M. Bradley, PhD StudentMEB

Nicholas W. Gilpin, PhDMEB

Nicole J. LeCapitaine, PhDMEB

Andrew A. Pellett, PhDN/AH

Andy Pitt, CRNACHNOChildren’s

Barry J. Potter, PhDMEB 7C10

Stefany D. Primeaux, PhDMEB

Flavia M. Souza-Smith,

Xu S. Teng, MD, PhD

John B. Zamjahn, PhDN/AH

Doing well in Physiology will require concentrated effort on your part. You Will Become Involved In Your Own Learning Process! The following tips will enhance your chances for success in this course:

  1. A cursory understanding of the material is only the foundation from which to begin studying. Use the questions in the textbook to help guide you to understanding the physiologic concept presented.
  2. Facts are only memorized; understanding physiology requires integration and application of concepts. Ask yourself what is the primary concept this unit covers! Then study to understand the application of that concept to physiologic regulation.
  3. Read carefully the assigned and relevant readings in the text before class sessions.
  4. Take your own notes during lectures. As soon after the lecture as possible, integrate your notes with the textbook (note tables and figures) and other lecture material. Look at the material from different angles. Set aside your prejudices about this course and the material so that you can have an entirely new experience with your learning.
  5. Form a study group and review this material by making one study partner “teach” the group. You don’t really get the understanding of physiology until you help another understand physiology.
  6. Apply facts and concepts presented in the lecture to the clinical scenarios presented in the textbook. I like to exercise as a clinical scenario because we can easily visualize that activity.

LECTURES, ATTENDANCE, TEXTBOOK

Lectures: Human Physiology, HS2410, meets Tues 8-10AM (LR#1) and Fri 8-10AM (LR#2), Nursing-Allied Health Bldg. Class begins at 8 AM!Lectures support and supplement the textbook. The textbook will help you understand basic physiological concepts so you can apply them to nursing care. Achieve a working knowledge of physiology; don’t just memorize physiological facts.

Textbook: Human Physiology: Mechanisms of Body Function by Widmaier, Raff, and Strang, 12th edition (McGraw-Hill: ISBN0073378100). Our PPT slides are NOT the textbook. You are responsible for the text materialIN ADDITION to what we present in class.READ THE BOOK!

Laboratory: The ECG (MEB-MDL #3) and PFT (MEB-MDL #6) labs are given Tues or Thurs, 1-5 PM. You need attend only one day for each of these labs (AbPsych students must have lab on Tues). These labs are on the 4th floor of the Medical Education Building (MEB). Clinical correlation labs will be presented as a case study (LR#1 N/AH), 1-4PM (all students will meet together for clinical correlation).

Cell Phones:Turn cell phones to vibrate during class; Pleasekeep them out of sight! If an emergency exists where you know you are called, take it out of the classroom. Please! Respect our learning environment!

Electronics: Computersare NOTpermitted to be used in the classroom;YouMAY use an ipad!You MAY record the lecture using a voice recorder! You may NOT video the lecture.

Tutoring: Tutoring from our graduate students MAY beavailable; Contact them, or others, for help!

Students with Disabilities: Students who have authenticated disabilities must petition the Nursing School Administrative Assistant Dean, who will then inform the course director about students who are to receive additional time and/or accommodations for exams or other course functions.

Academic honesty: Use of any unauthorized material or method other than your knowledge and memory to answer questions on an exam or quiz constitutes cheating and will result in failure of that exam and possibly failure of the course. The Dean of the School of Nursing will be notified.

Clickers: Class Key N72203E825; Use for HS2410 Human Physiology Fall2011. Our Institution is listed as: Louisiana State University Health Sciences Center School of Nursing.

EXAMINATIONS AND GRADING

Exam Schedule:Six unit examswill be given during the course. Exam 6 tests Endocrine Physiology, AND will comprehensively test the previous 5 sections. Examinations are scheduled Fridays 12PM – 5 PM (Exam #2 is 12:30-5:30) in the Computer Assisted Testing Lab on the 5th Floor, N/AH, and will be in two assigned groups, one starting at 12 NOON and the other at 2:30 PM. You will have 2 hours to complete the exam once the exam starts.Students with disabilities will be seated in a special testing room at 12PM, and you will be given 3 hr to complete the exam once you start. There will be no extension of time.

Attire and Personal Material: DO NOT wear caps and other headgearduring the exam. Pencil and paper are permitted should you need them. Turn them in to me and SIGN them in my presence before leaving the NSTC! Basic function calculators may be used, if needed! WATER and FOOD are NOTPERMITTED in the Computer Lab! LEAVE CELL PHONES in your book bag! If you expect an emergency call during the exam, silence your cell phone, leave it with the proctor so we can notify you should you receive a call. Book bags and other material MUST be stored in designated storage areas, off the floor, out of the way!

Exam Format: Examinations are multiple-choice questions that utilize clinical scenarios whichwill emphasize understandingof physiologic principles (know and apply facts). Questions from a general clinical scenario will testwhether you understand fundamental concepts we have studied and discussed in class.

Late Arrival for Exam: Exam instructions start at 12:00 and 2:30PM. Get seated rapidly! Exams are limited to exactly 2 hours, and will start AFTER instructions are given. Should you arrive late for the exam, your exam will end at the same time as the other students. Should you arrive one-half hour after the exam starts, you will have missed the exam, and will have to make arrangements to take a make-up exam.

Missing an Exam: Students must have a legitimate excuse for missing an examination. Please inform the Course Director before the exam. If a student misses an exam because of an emergency, informs the course director within 24 hours after the exam has been given, has the necessary legal or medical documentation for the absence,then the student will be offered a make-up exam. Make-up exams may be multiple choice, but more probably will be oral and essay format. Students with a valid excuse must take a “make-up” exam within one week of returning to school. It is the student’s responsibility to schedule this make-up exam! Failure to take the exam or the make-up exam results in a “0” for that exam. THIS DOES NOT APPLY TO QUIZZES!

Exam Reviews: Exams are evaluative, not instructional. We will NOT review exams nor exam questions.

Clicker Quizzes:Clickers are your property. Carry extra batteries! Make certain they work! Be sure they connect with the class computer (number recognized on screen) and with einstruction (quiz recorded under course). Check with einstruction.com every quiz to MAKE SURE your clickers made contact with their site so you receive credit for the quizzes you have taken. Notify me IMMEDIATELY if contact was not made!

Clicker quizzes will be used daily throughout the semester and throughout the class period. Quizzes are given at random in class! They are taken in class, ONLY! One point will be given for attemptingto answer the question; One point will be given for answering that question correctly. All clicker points constitute one exam (Ex#7) for the semester. Ex#7 points are determined by dividing the [[number correct]/[total]] to determine your percent score for that ‘exam.’ If we have 100 clicker quizzes during the semester, and you score 180 of the 200 total points, then, as per this example, your score is 180/200 = 90%. Thus, the points for Exam #7 is 90.

STUDENT EVALUATION:

Exams are graded as percent scores: %Score = [Correct/Total]. No curve will be used to adjust scores.

Final grades are based on your TOTAL percent score (700 pts) from the six exams (600 pts) and the clickers (100 pts). The grading scale is 90-80-70-60 for A-B-C-D respectively. These scores are ABSOLUTE. A final score of 629 is a “B” and a score of 630 is an “A.”

GRADING SYSTEM: Final grades are based on 90% (A), 80% (B), 70% (C), 60% (D), and 59% (F):

ExamPtsFinalPercentageTotal Points

Exam I100A90 – 100630 - 700

Exam II100B80 – 89560 - 629

Exam III100C70 – 79490 - 559

Exam IV 100D60 – 69420 - 489

Exam V100F 59000 –419

Exam VI100

Exam VII (Clickers)100

Total Points700

No.Day/DateTIMETOPICInstructor___

01F 17 Aug8Homeostasis: Maintenance of Internal Environment (Ch 1)Shepherd

02F 17 Aug9Cell Physiology: Cell Function – Metabolism (Ch 3)Shepherd

03 T 21 Aug 8 Cell Physiology: Membranes – Molecular Structure (Ch 3) Primeaux

04 T 21 Aug 9 Cell Physiology: Diffusion, Osmosis (Ch 4) Primeaux

Lab#1 T 21 Aug 1PM Solutes-Solvents-Fluid Compartments (LR #1) Teng

05 F 24 Aug 8 Cell Physiology: Membrane Transport (Ch 4) Primeaux

06 F 24 Aug 9BioCommunication: Electrical Properties of membranes (Ch 4) Primeaux

07 T 28 Aug 8BioCommunication: Action and Graded Potentials (Ch 6) Primeaux

08 T 28 Aug 9BioCommunication: Synapses and signaling (Ch 6) Primeaux

LAB#2 T 28 Aug 1PMFluids and Resuscitation (LR #1) Teng

09 F 31 Aug 8 BioCommunication: Neurotransmitters & Receptors (Ch 5) Primeaux

10 F 31 Aug 9 BioCommunication: Sensory Physiology (Ch 7) Primeaux

Exam #1: 12-5PM FRI, 31 Aug 2012 Lecture 01-08, Lab 1-2 (CAL, N/AH 5th Floor)

11T 04 Sept8BioCommunication: NeuroHumoralCommunication (Ch 6,11)Shepherd

12T 04 Sept9BioCommunication: Control of Body Movement (Ch 10)ShepherdLAB#3 T 04 Sept 1PM CASE STUDY: Botulinus Toxin; Tetanus Toxin (LR#1) Shepherd

13F 07Sept8BioCommunication: Skeletal Muscle Contraction (Ch 9)Shepherd

14F 07Sept9BioCommunication: Skeletal Muscle Contraction (Ch 9)Shepherd

15T 11Sept8BioCommunication: Cardiac and Smooth Muscle (Ch 10)Shepherd

16T 11Sept9BioCommunication: Autonomic Nervous System (Ch 6)Shepherd

LAB#4 T11Sept1PMNeurologic Exam (LR #1)Shepherd

17F 14Sept8BioCommunication: States of Consciousness (Ch 8)Gilpin

18F 14Sept9BioCommunication: Learning and Behavior (Ch 8)Gilpin

19T 18Sept8Cardiovascular: Overall Design and Function (Ch 12)Gardner

20T 18Sept9Cardiovascular: ECG and Electrical activity of the heartGardner

LAB#5 TTh 18&20 Sept1PM ECG Lab (MDL #6)Gardner

21F 21Sept8Cardiovascular: Heart as a Pump (Ch 12)Gardner

22F 21Sept9Cardiovascular: Cardiac Cycle – Wiggers and P/V Gardner

Exam #2: 12:30-5:30PM FRI, 21Sept 2012 Lecture 09-18, Lab 3 (CAL, N/AH 5th Floor)

23T 25 Sept8Cardiovascular: Cardiac Cycle/Cardiac Output (Ch 12)Gardner

24T 25 Sept9Cardiovascular: Vasculature and Microcirculation (Ch 12)Souza-Smith

LAB#6 T25 Sept1PMCASE STUDY: Arrhythmias (LR#1)Gardner

25F 28 Sept8Cardiovascular: Microcirculation and Venous Return (Ch 12)Souza-Smith

26F 28 Sept9Cardiovascular: Control of Cardiovascular FunctionBradley

27T 02 Oct8CV: Blood Components(Ch 12)Potter

28T 02 Oct9CV: Hemostasis (Ch 12)Potter

LAB#7 T02 Oct1PMCV: Regulation of Mean Arterial Blood Pressure (LR #1)Shepherd

29F 05 Oct8CV: Blood Clotting and INR (notes and Ch 18)Potter

30F 05 Oct9CV: Wound Healing (notes and Ch 18)Potter

No.Day/DateTIMETOPIC Instructor

31T 09 Oct8CV: Innate Immunity (Ch 18)Potter

32T 09 Oct9CV: Acquired Immunity (Ch18)Potter

LAB #8 T 09Oct1PMCASE STUDY:Anemias (LR#1)Potter

33F 12 Oct8Respiratory: Mechanics of Breathing (Ch 13)Pellett

34F 12 Oct9Respiration: Lung volumes; Gas Exchange (Ch 13)Pellett

Exam #3: 12-5PM FRI, 12 Oct 2012 Lecture 19-32, Lab 4-5 (CAL, N/AH 5th Floor)

35T 16 Oct8Respiration: Ventilation and Perfusion (Ch 13)Pellett

36T 16 Oct9Respiration: Gas Transport (Ch 13)Pellett

37F 19 Oct8Respiration: Control of Breathing (Ch 13)Pellett

38F 19 Oct9Respiratory: Acid-Base Balance and Arterial Blood GasesPellett

39T 23 Oct8Renal: Renal structure, function, clearance, GFR (Ch 14)LeCapitaine

40T 23 Oct9Renal: Tubular Function I (Ch 14)LeCapitaine

LAB#9TTh23 & 25 Oct 1PMRespiratory Function (MDL 6)Zamjahn

41F 26 Oct8Renal: Tubular Function II (Ch 14)LeCapitaine

42F 26 Oct9Renal: Water Balance (Ch 14)LeCapitaine

43T 30Oct8Renal: Electrolyte Balance (Ch 14)LeCapitaine

44T 30 Oct9Renal: Acid-Base Balance (Ch 14)LeCapitaine

LAB#10 Tue 30 Oct1PMArterial Blood Gases(LR #1)Pitt

45F 02 Nov8GI – Introduction to the GI Tract (Ch 15)Potter

46F 02 Nov9GI – Digestion and Absorption (Ch 15)Potter

Exam #4: 12-5PM FRI, 02Nov 2012 Lecture 33-44, Lab 6-7 (CAL, N/AH 5th Floor)

47T 06 Nov8GI – Cephalic Phase of Digestion (Ch 15)Potter

48T 06 Nov9GI – Gastric Phase of Digestion (Ch 15)Potter

LAB#11 Tue 06 Nov1PMCASE STUDY: Metabolism/Temperature Regulation(LR#1)Shepherd

49F 09 Nov8GI – Intestinal Phase of Digestion (Ch 15)Potter

50F 09 Nov9GI – Hepatobiliary Phase of Digestion (Ch 15)Potter

51T 13 Nov8Endo – Hypothalamic-Pituitary Axis (Ch 11)Shepherd

52T 13 Nov9Endo – Growth Hormone (Ch 11)Shepherd

LAB#12 Tue 13 Nov1PMEndo – Pancreas and Diabetes (Ch 16) (LR #1)Shepherd

53F 16 Nov8Endo –Thyroid Hormone (Ch 11)Shepherd

54F 16 Nov9Endo – Parathyroid Hormone (Ch11)Shepherd

EXAM #5: 12 – 5 PMFri, 16Nov 2012Lecture 45-52, Lab8 (CAL, N/AH 5th Floor)

55T 20 Nov8Endo – Adrenal Cortical Hormones (Ch 11)Shepherd

56T 20 Nov9Endo – Adrenal Medullary Hormones (Ch 11)Shepherd

57T 27 Nov8Endo – Male ReproductionShepherd

58T 27 Nov9Endo – Male ReproductionShepherd

LAB#13 Tue 27 Nov 1PMPhysiologic Reserve – A General Review of the CourseShepherd

EXAM #6: 12- 5 PMTue 30Nov 2012Lecture 1-56, Lab 1-9 (CAL, N/AH 5th Floor)

Mon / Tuesday / Wed / Thu / Friday
Aug / 13 / 14 / 15 / 16 / 17
L01 Homeostasis
L02 Cell Function - Metabolism
20 / 21
L03 Cell Function – Membranes
L04 Diffusion – Osmosis
Lab 1: Solutes-Solvents-Compartments (LR#1) / 22 / 23 / 24
L05 MembraneTransport
L06 Electrical Properties of Membranes
27 / 28
L07 Actionand Graded Potentials
L08 Synapses and Signaling
Lab 2: ResuscitationFluids (LR#1) / 29 / 30 / 31
L09 Neurotransmitters and Receptors
L10 Sensory Physiology
Exam #1: L01-L08, Lab 1-2
Sept / 3 / 04
L11 Neural Communication
L12 Homonal Communication
Lab 3: Botulinus & Tetanus Toxin(LR#1) / 05 / 06 / 07
L13 Skeletal Muscle Contraction
L14 Skeletal Muscle Contraction
10 / 11
L15 Cardiac-Smooth Muscle
L16 Autonomic Nervous System
Lab 4: Neurologic Exam (LR#1) / 12 / 13 / 14
L17 States of Consciousness
L18 Learning and Behavior
17 / 18
L19 CV Overall Design/Function
L20 ECG and Electrical activity
Lab5: ECG (MDL 6) / 19 / 20
Lab: ECG / 21
L21 The Heart as a Pump
L22 Cardiac Cycle – Wiggersand P/V
Exam #2: L09-L18, Lab 3-5
24 / 25
L23 Vasculature and Blood Flow Distribution
L24 Vasculature and Microcirculation
Lab 6: Arrhythmias(LR#1) / 26 / 27 / 28
L25 Venous Return
L26 Control of CV Function
Oct / 01 / 02
L27 Blood
L28 Hemostasis
Lab7: MABP (LR#1) / 03 / 04 / 05
L29 Blood Clotting
L30 Wound Healing
08 / 09
L31 Innate Immunity
L32 Acquired Immunity
Lab8: Anemias(LR#1) / 10 / 11 / 12
L33 Respiratory: Mechanisms of Breathing
L34 Respiratory: Gas Exchange
Exam #3: L19-L30, Lab 6-8
15 / 16
L35 Respiratory: Ventilation/Perfusion
L36 Respiratory: Gas Transport / 17 / 18 / 19
L37 Respiratory: Control of Breathing
L38 Respiratory: Acidosis - Alkalosis
22 / 23
L39 Renal: Structure/ Clearance/Filtration
L40 Renal: Tubular Function
Lab 9: PFT (MDL 6) / 24 / 25
Lab: PFT / 26
L41 Renal: Tubular function
L42 Renal: Water Balance
29 / 30
L43 Renal: Electrolyte Balance
L44 Renal: H+HCO3- Balance
Lab 10: ABG’s (LR#1) / 31 / 01 / 02
L45 Intro to GI Tract
L46 Digestion and Absorption
Exam #4: L31-L44, Lab 9-10
Nov / 05 / 06
L47 GI: Cephalic phase of digestion
L48 GI: Gastric phase of digestion
Lab 11: TemperatureRegulation(LR#1) / 07 / 08 / 09
L49: Intestinal phase of digestion
L50: Hepatobiliary digestion
12 / 13
L51 Hypothalamic-Pituitary Axis
L52 Growth Hormone
Lab 12: Pancreas and Diabetes (LR#1) / 14 / 15 / 16
L53 Thyroid Hormone
L54 Parathyroid Hormone
Exam #5: L45-L52, Lab 11-12
19 / 20
L55 Adrenal Cortical Hormones
L56 Adrenal Medullary Hormones / 21 / 22 - 23
THANKSGIVING
25 / 26
L57 Male Reproduction
L58 Female Reproduction
Lab 13: Physiologic Reserve (LR#1) / 27
Reading
Day / 28 / 30
Exam #6: L01-L58, Lab 1-13

Class Name: HS2410 Fall 2012

Class Key: N72203E825

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