CURRICULUM VITAE
Name: Kisaburo Nagamune
Sex: Male
Date of Birth: October 10, 1967
Place of Birth: Hiroshima, Japan
Nationality: Japanese
Marital Status: Married
Present address: (Home) 40N. Kingshighway 8C, St. Louis, MO 63108
(Business) Department of Molecular Microbiology
Washington University School of Medicine
660S. Euclid Avenue, Campus Box 8230, St. Louis, MO63110-1093
(TEL) 314-362-8874
(FAX) 314-286-0060
(E-mail)
Education:
1996 Ph. D. Graduate School of Medicine, Osaka University, Osaka, Japan
(Thesis: Intramolecular chaperone activity of the pro-region of Vibrio cholerae El Tor cytolysin.)
1992 D.V.M. Department of Veterinary Science, College of Agriculture,
Osaka Prefecture University, Osaka, Japan
(Thesis: Gametocytogenesis induction by Berenil in cultured
Plasmodium falciparum.)
1986 Graduated from a High School
Research and professional experience:
2004-Present Postdoctoral Research Scholar
Washington University School of Medicine
1999-Present Research Associate
Department of Immunoregulation
Research Institute for Microbial Diseases, Osaka University
Osaka, Japan
1996-1999 Postdoctoral Research Fellow
Department of Immunoregulation
Research Institute for Microbial Diseases, Osaka University
Osaka, Japan
Membership:
The Japanese Biochemical Society
The Japanese Society of Parasitology
The Molecular Biology Society of Japan
Awards:
Academic Award of Research Institute for Microbial Diseases in 2000
Young Scientist’s Award of The Japanese Society of Parasitology in 2004
Prize for the Best Presentation at the Molecular Parasitology Meeting XV, 2004
LIST OF PUBLICATIONS
1) Ono, T., Ohnishi, Y., Nagamune, K. and Kano, M. “Gametocytogenesis induction by Berenil in cultured Plasmodium falciparum.” Exp. Parasitol. 1993, 77: 74-78.
2) Nagamune, K., Yamamoto, K. and Honda, T. “Cloning and sequencing of a novel hemolysis gene of Vibrio cholerae.” FEMS Microbiol. Lett. 1995, 128: 265-269.
3) Nagamune, K., Yamamoto, K., Naka, A., Matsuyama, J., Miwatani, T. and Honda, T. “In vitro proteolytic processing and activation of the recombinant precursor of El Tor cytolysin/hemolysin (pro-HlyA) of Vibrio cholerae by soluble hemaggultinin/protease of V. cholerae, trypsin and other proteases.” Infect. Immun. 1996, 64. 4655-4658
4) Nagamune, K., Yamamoto, K. and Honda, T. “Intramolecular chaperone activity of the pro-region of Vibrio cholerae El Tor cytolysin.” J. Biol. Chem. 1997, 272. 1338-1343
5) Nagamune, K., Nozaki, T., Maeda, Y., Ohishi, K. Fukuma, T., Hara, T., Schwarz, R.T., Sütterlin, C., Brun, R., Riezman, H. and Kinoshita, T. “Critical roles of glycosylphosphatidylinositol for Trypanosoma brucei.” PNAS 2000, 97. 10336-10341
6) Nagamune, K. and Kinoshita, T. “GPI biosynthetic pathway as a target for antiprotozoan drugs.” Tanpakushitsu Kakusan Koso. 2002, 47. 30-36
7) Ohishi, K., Nagamune, K., Maeda, Y. and Kinoshita, T. “Two subunits of glycosylphosphatidylinositol transamidase, GPI8 and PIG-T, form a functionally important intermolecular disulfide bridge.” J. Biol. Chem. 2003, 278. 13959-13967.
8) Nagamune, K., Ohishi, K., Ashida, H., Hong, Y., Hino, J., Kangawa, K., Inoue, N., Maeda Y., and Kinoshita, T. “GPI transamidase of Trypanosoma brucei has two novel (TTA1 and TTA2) and three common subunits.” PNAS 2003, 100. 10682-10687.
9) Nagamune, K., Acosta-Serrano, A., Uemura, H., Brun, R., Kunz-Renggli, C., Maeda, Y., Ferguson, M.A.J., and Kinoshita, T. “Surface sialic acids taken from the host allow trypanosome survival in tsetse fly vectors.” J. Exp. Med. 2004, 199. 1445-1450
10) Kubata, B.K., Nagamune, K., Murakami, N., Merkel, P., Kabututu, Z., Martin, S.K., Kalulu, T.M., Mustakuk, H., Yoshida, M., Ohnishi-Kameyama, M., Kinoshita, T., Duszenko, M., and Urade, Y. “Kola acuminata proanthocyanidins: a class of anti-trypanosomal compounds effective against Trypanosoma brucei.” Int. J. Parasitol. 2005, 35. 91-103
11) Chini, E.N., Nagamune, K., Wetzel, D.M., and Sibley, L.D. “Evidence that the cADPR signalling pathway controls calcium-mediated microneme secretion in Toxoplasma gondii.” Biochem J. 2005, 389. 269-77.
12) Hong, Y., Nagamune, K., Ohishi, K., Morita, Y.S., Ashida, H., Maeda, Y., and Kinoshita, T. “TbGPI16 is an essential component of GPI transamidase in Trypanosoma brucei.” FEBS Lett. 2006, 580. 603-6.