Mir-7 / Upregulated in pancreatic and stomach cancer.1
Mir-15a / Downregulated in Chronic Lymphocytic Leukemia and pituitary adenoma, induced in the regenerating mouse pancreas.2,3,4
mir-21 / Upregulated in pancreas cancer, glioblastoma, breast cancer, colon cancer, lung cancer, prostate cancer, stomach cancer, hepatocellular carcinoma, uterine leiomyomas, ovarian cancer, cholangiocarcinoma, and cardiac hypertrophy.1,5-12
mir-23a / Upregulated in hepatocellular carcinoma, bladder cancer, breast cancer, pancreatic cancer, stomach cancer, and in cardiac hypertrophy.1,5,7,12,13,14
Mir-23b / Upregulated in hepatocellular carcinoma, bladder cancers, Human uterine leiomyomas, breast cancer, pancreas cancer, and in cardiac hypertrophy. 1,5,7,9,12,13,14
Mir-24 / Upregulated in hepatocellular carcinoma, breast cancer, lymphoma, colon cancer, pancreas cancer, stomach cancer, down in prostate cancer, inhibits erythropoiesis; upregulated in cardiac hypertrophy.1,7,12,13,15
Mir-26a / Downregulated in human thyroid anaplastic carcinomas, modulates late osteoblasts differentiation, up in pancreas cancer. 1,16,17
Mir-26b / Upregulated in bladder cancers, up in pancreas cancer.1,14
Mir-27a / Upregulated in renal cell carcinoma, Human uterine leiomyomas, pancreas cancer, prostate cancer.1,9,14
Mir-30b / Upregulated in pancreas cancer1
Mir-30d / Upregulated in pancreas cancer, prostate cancer, down in human thyroid anaplastic carcinomas, chronic lymphocytic leukemia, lung cancer1,16,18
Mir-93 / Upregulated in hepatocellular carcinoma, pancreas cancer, prostate cancer, down in cardiac hypertrophy.1,12,13
Mir-103 / Upregulated in bladder cancers, pancreatic cancer, stomach cancer.1,5,14
Mir-106a / Up in lung, gastric, colon, pancreas and prostate cancer, hepatocellular carcinoma, T-lymphoma, T-cell leukemia, neuroblastoma, down during megakaryocytopoiesis.1, 13,19,20,21,22
Mir-107 / Upregulated in colon cancer, pancreas cancer, stomach cancer1,5
Mir-125b / Up in pancreas cancer, stomach cancer, up in cardiac hypertrophy, down in human thyroid anaplastic carcinomas, human ovarian cancer, breast cancer, prostate cancer.1,5,710,12,16
Mir-148a / Upregulated in lung cancer, prostate cancer, downregulated in pancreatic cancer.1,5
Mir-148b / Upregulated in lung cancer, prostate cancer, downregulated in pancreatic cancer.1,5
Mir-155 / Upregulated in bad prognosis in Chronic lymphocytic leukemia and lung cancer; upregulated in breast cancer, Hodgkin lymphoma, pediatric Burkitt lymphoma, colon cancer, lung cancer; downregulated in pancreas cancer (1), upregulated in pancreas cancer (5); induced during the macrophage inflammatory response.1,5,7,18,23,24
Mir-181a / Upregulated in breast cancer, pancreas cancer, down in chronic lymphocytic leukemia, glioblastoma; correlates with morphological sub-class of acute myeloid leukaemia; role in T cell development.1,5,7,18,25,26,27,28
Mir-181b / Upregulated in acute lymphoblastic leukemia, breast cancer, pancreas cancer, prostate cancer, downregulated in glioblastoma, downregulated in cardiac hypertrophy.1,5,7,12,,25,29
Mir-181c / Upregulated in pancreas cancer, downregulated in glioblastoma.1,5,25
Mir-191 / Upregulated in stomach cancer, colon cancer, lung cancer, pancreas cancer, prostate cancer.1
Mir-192 / Up in stomach cancer, pancreas cancer, upregulated in diabetic kidney glomeruli.1,30
Mir-195 / Up in Chronic lymphocytic leukemia, up in cardiac hypertrophy, higher in the regenerating mouse pancreas as compared to embryonic day, up in prostate cancer.1,4,12,29
Mir-200a / Upregulated in human ovarian cancer.10
Mir-210 / Upregulated in breast cancer, lung cancer, pancreas cancer, upregulated in patients with preeclampsia and small for gestational age (SGA), downregulated in ovarian cancer.1,5,31,32
Mir-213 / Upregulated in breast cancer, colon cancer, pancreas cancer.1.5,7
Mir-214 / Upregulated in pancreas cancer, prostate cancer, stomach cancer, up in cardiac hypertrophy; modulates Hedgehog signaling to specify muscle cell fate.1,12,33
Mir-373 / Upregulated in testicular germ-cell tumor cell lines.34
Let-7-i / Upregulated in breast cancer.7
Mir-15b / Upregulated in the regenerating mouse pancreas.4
Mir-16 / Downregulated in Chronic Lymphocytic Leukemia, pituitary adenoma and breast cancer; upregulated in lung cancer, prostate cancer, pancreas cancer; upregulated in the regenerating mouse pancreas.1,2,3,4,7
Mir-20a / Upregulated in hepatocellular carcinoma, colon cancer, pancreas cancer, prostate cancer, downregulated during megakaryocytopoiesis.1,13,22
Mir-20b / Upregulated in hepatocellular carcinoma, T cell leukemia, downregulated during megakaryocytopoiesis. 13,20,22
Mir-26b / Upregulated in bladder cancer, up in pancreas cancer. 1,14
Mir-29b / Upregulated in breast cancer, colon cancer, pancreas cancer and prostate cancer, downregulated in cholangiocarcinoma, human uterine leiomyomas; role in insulin resistance.1,7,9,11,35
Mir-30b / Upregulated in pancreas cancer1
Mir-101 / Upregulated in megakaryoblastic leukemic cell lines, up in prostate cancer.1,22
Mir-122a / Downregulated in hepatocellular carcinoma, upregulated in breast cancer.7,13
Mir-141 / Upregulated in human ovarian cancer, cholangiocarcinoma, lung cancer.1,10,11
Mir-195 / Up in Chronic lymphocytic leukemia, up in cardiac hypertrophy, higher in the regenerating mouse pancreas as compared to embryonic day, up in prostate cancer.1,4,12,29
Mir-197 / Downregulated in human uterine leiomyomas.9
Mir-224 / Downregulated in breast cancer, Upregulated in pancreas cancer.1,7
Let-7-a / Downregulated in lung cancer, chronic lymphocytic leukemia, breast cancer, prostate cancer. Upregulated in hepatocellular carcinoma.1,7,13,18
Let-7-c / Downregulated in prostate cancer, role in liver oncogenesis.1,36
Let-7-d / Downregulated in breast cancer, upregulated in prostate cancer.1,7
Let-7-f / Upregulated in renal cell carcinoma, downregulated in breast cancer, promotes angiogenesis.7,14,37
Let-7-g / Upregulated in lung cancer.1

Supplementary References:

1.  Volinia S, Calin GA, Liu CG, Ambs S, Cimmino A, Petrocca F et al A microRNA expression signature of human solid tumors defines cancer gene targets. Proc Natl Acad Sci U S A 2006; 103: 2257-61.

2.  Calin GA, Pekarsky Y, Croce CM. The role of microRNA and other non-coding RNA in the pathogenesis of chronic lymphocytic leukemia. Best Pract Res Clin Haematol. 2007; 20: 425-37.

3.  Bottoni A, Piccin D, Tagliati F, Luchin A, Zatelli MC, degli Uberti EC. miR-15a and miR-16-1 down-regulation in pituitary adenomas. J Cell Physiol. 2005; 204: 280-5.

4.  Joglekar MV, Parekh VS, Mehta S, Bhonde RR, Hardikar AA. MicroRNA profiling of developing and regenerating pancreas reveal post-transcriptional regulation of neurogenin3. Dev Biol. 2007; 311: 603-12.

5.  Bloomston M, Frankel WL, Petrocca F, Volinia S, Alder H, Hagan JP et al MicroRNA expression patterns to differentiate pancreatic adenocarcinoma from normal pancreas and chronic pancreatitis. JAMA 2007; 297: 1901-8.

6.  Chan JA, Krichevsky AM, Kosik KS. MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells. Cancer Res. 2005; 65: 6029-33

7.  Iorio MV, Ferracin M, Liu CG, Veronese A, Spizzo R, Sabbioni S et al MicroRNA gene expression deregulation in human breast cancer. Cancer Res. 2005; 65: 7065-70..

8.  Meng F, Henson R, Wehbe-Janek H, Ghoshal K, Jacob ST, Patel T. MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer. Gastroenterology. 2007; 133: 647-58.

9.  Wang T, Zhang X, Obijuru L, Laser J, Aris V, Lee P et al A micro-RNA signature associated with race, tumor size, and target gene activity in human uterine leiomyomas. Genes Chromosomes Cancer. 2007; 46: 336-47.

10.  Iorio MV, Visone R, Di Leva G, Donati V, Petrocca F, Casalini P et al MicroRNA signatures in human ovarian cancer. Cancer Res. 2007; 67: 8699-707

11.  Meng F, Henson R, Lang M, Wehbe H, Maheshwari S, Mendell JT et al. Involvement of human micro-RNA in growth and response to chemotherapy in human cholangiocarcinoma cell lines. Gastroenterology. 2006; 130: 2113-29

12.  van Rooij E, Sutherland LB, Liu N, Williams AH, McAnally J, Gerard RD et al A signature pattern of stress-responsive microRNAs that can evoke cardiac hypertrophy and heart failure. Proc Natl Acad Sci U S A. 2006; 103: 18255-60.

13.  Kutay H, Bai S, Datta J, Motiwala T, Pogribny I, Frankel W, Jacob ST, Ghoshal K. Downregulation of miR-122 in the rodent and human hepatocellular carcinomas. J Cell Biochem. 2006 Oct 15;99(3):671-8.

14.  Gottardo F, Liu CG, Ferracin M, Calin GA, Fassan M, Bassi P et al Micro-RNA profiling in kidney and bladder cancers. Urol Oncol. 2007; 25: 387-92.

15.  Wang Q, Huang Z, Xue H, Jin C, Ju XL, Han JD et al MicroRNA miR-24 inhibits erythropoiesis by targeting activin type I receptor ALK4. Blood 2007;Sep 28 [Epub ahead of print]

16.  Visone R, Pallante P, Vecchione A, Cirombella R, Ferracin M, Ferraro A et al Specific microRNAs are downregulated in human thyroid anaplastic carcinomas. Oncogene 2007; 26: 7590-5.

17.  Luzi E, Marini F, Carbonell Sala S, Tognarini I, Galli G, Luisa Brandi M. Osteogenic Differentiation of Human Adipose Tissue-Derived Stem Cells is modulated by the miR-26a Targeting the SMAD1 Transcription Factor. J Bone Miner Res. 2007 Oct 8 [Epub ahead of print]

18.  Marton S, Garcia MR, Robello C, Persson H, Trajtenberg F, Pritsch O et al Small RNAs analysis in CLL reveals a deregulation of miRNA expression and novel miRNA candidates of putative relevance in CLL pathogenesis. Leukemia 2007; Nov 8 [Epub ahead of print]

19.  Lum AM, Wang BB, Li L, Channa N, Bartha G, Wabl M. Retroviral activation of the mir-106a microRNA cistron in T lymphoma. Retrovirology 2007; 4:5.

20.  Landais S, Landry S, Legault P, Rassart E. Oncogenic potential of the miR-106-363 cluster and its implication in human T-cell leukemia. Cancer Res. 2007; 67: 5699-707.

21.  Schulte JH, Horn S, Otto T, Samans B, Heukamp LC, Eilers UC et al MYCN regulates oncogenic MicroRNAs in neuroblastoma. Int J Cancer. 2008; 122: 699-704.

22.  Garzon R, Pichiorri F, Palumbo T, Iuliano R, Cimmino A, Aqeilan R MicroRNA fingerprints during human megakaryocytopoiesis. Proc Natl Acad Sci U S A. 2006; 103: 5078-83

23.  Kluiver J, Poppema S, de Jong D, Blokzijl T, Harms G, Jacobs S, Kroesen BJ, van den Berg A. BIC and miR-155 are highly expressed in Hodgkin, primary mediastinal and diffuse large B cell lymphomas. J Pathol. 2005; 207: 243-9.

24.  O'Connell RM, Taganov KD, Boldin MP, Cheng G, Baltimore D. MicroRNA-155 is induced during the macrophage inflammatory response. Proc Natl Acad Sci U S A. 2007; 104: 1604-9.

25.  Ciafrè SA, Galardi S, Mangiola A, Ferracin M, Liu CG, Sabatino G et al Extensive modulation of a set of microRNAs in primary glioblastoma. Biochem Biophys Res Commun. 2005; 334:1351-8.

26.  Debernardi S, Skoulakis S, Molloy G, Chaplin T, Dixon-McIver A, Young BD. MicroRNA miR-181a correlates with morphological sub-class of acute myeloid leukaemia and the expression of its target genes in global genome-wide analysis. Leukemia 2007; 21: 912-6.

27.  Li QJ, Chau J, Ebert PJ, Sylvester G, Min H, Liu G et al miR-181a is an intrinsic modulator of T cell sensitivity and selection. Cell 2007; 129: 147-61.

28.  Neilson JR, Zheng GX, Burge CB, Sharp PA. Dynamic regulation of miRNA expression in ordered stages of cellular development. Genes Dev. 2007; 21: 578-89.

29.  Zanette DL, Rivadavia F, Molfetta GA, Barbuzano FG, Proto-Siqueira R, Silva-Jr WA. miRNA expression profiles in chronic lymphocytic and acute lymphocytic leukemia. Braz J Med Biol Res. 2007; 40: 1435-40

30.  Kato M, Zhang J, Wang M, Lanting L, Yuan H, Rossi JJ, Natarajan R. MicroRNA-192 in diabetic kidney glomeruli and its function in TGF-beta-induced collagen expression via inhibition of E-box repressors. Proc Natl Acad Sci U S A. 2007; 104: 3432-7.

31.  Pineles BL, Romero R, Montenegro D, Tarca AL, Han YM, Kim YM et al Distinct subsets of microRNAs are expressed differentially in the human placentas of patients with preeclampsia. Am J Obstet Gynecol. 2007; 196: 261.e1-6

32.  Giannakakis A, Sandaltzopoulos R, Greshock J, Liang S, Huang J, Hasegawa K et al miR-210 links hypoxia with cell cycle regulation and is deleted in human epithelial ovarian cancer. Cancer Biol Ther. 2007 Nov 14;7(2) [Epub ahead of print]

33.  Flynt AS, Li N, Thatcher EJ, Solnica-Krezel L, Patton JG. Zebrafish miR-214 modulates Hedgehog signaling to specify muscle cell fate. Nat Genet. 2007; 39: 259-63

34.  Voorhoeve PM, le Sage C, Schrier M, Gillis AJ, Stoop H, Nagel R et al A genetic screen implicates miRNA-372 and miRNA-373 as oncogenes in testicular germ cell tumors. Cell 2006; 124: 1169-81.

35.  He A, Zhu L, Gupta N, Chang Y, Fang F. Overexpression of micro ribonucleic acid 29, highly up-regulated in diabetic rats, leads to insulin resistance in 3T3-L1 adipocytes. Mol Endocrinol. 2007; 21: 2785-94.

36.  Shah YM, Morimura K, Yang Q, Tanabe T, Takagi M, Gonzalez FJ. Peroxisome proliferator-activated receptor alpha regulates a microRNA-mediated signaling cascade responsible for hepatocellular proliferation. Mol Cell Biol. 2007; 27: 4238-47

37.  Kuehbacher A, Urbich C, Zeiher AM, Dimmeler S. Role of Dicer and Drosha for endothelial microRNA expression and angiogenesis. Circ Res. 2007; 101: 59-68